Abstract：
OBJECTIVE:To determine whether serum interleukin (IL)-8 concentration can be measured in patients with ovarian endometrioma and whether this measurement is a useful tool in diagnosing this disease. DESIGN:A controlled clinical study and an in vitro study. SETTING:Department of Obstetrics and Gynecology, Tottori University, Japan. PATIENT(S):Seventy patients with ovarian endometrioma and 21 patients with benign ovarian cyst. INTERVENTION(S):Laparoscopic surgery or laparotomy for ovarian endometriomas or benign ovarian cyst was performed. Preoperative blood samples were obtained. Endometriotic stromal cells obtained from nine patients with endometrioma were cultured. MAIN OUTCOME MEASURE(S):Interleukin-8 concentration in the serum or supernatant of the cell culture was measured with use of ELISA. RESULT(S):The serum concentration of IL-8 in patients with endometrioma was significantly higher than in patients with benign ovarian cyst. The serum IL-8 threshold (25 pg/mL) had a higher sensitivity (71.4%) for diagnosing ovarian endometrioma than did serum CA-125 level. The increased rates of IL-8 concentration in the culture supernatants after adding tumor necrosis factor alpha were significantly higher in patients whose serum IL-8 levels were >or=25 pg/mL than in those with levels <25 pg/mL. CONCLUSION(S):Measuring of serum IL-8 concentration may be a valuable tool in diagnosing endometriosis.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Ohata Y,Harada T,Miyakoda H,Taniguchi F,Iwabe T,Terakawa Ndoi
10.1016/j.fertnstert.2007.07.1355subject
Has Abstractpub_date
2008-10-01 00:00:00pages
994-9issue
4eissn
0015-0282issn
1556-5653pii
S0015-0282(07)03008-7journal_volume
90pub_type
杂志文章abstract：OBJECTIVE:Formin-2 (Fmn2) mutant mice produce oocytes with meiosis I arrest. Our aim was to describe the human FORMIN-2 (FMN2) gene and to identify DNA sequence polymorphisms in patients with unexplained infertility and multiple failed IVF cycles. DESIGN:Institutional review board-approved observational case-control s...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.10.051
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVE:To determine the effects of a low-dose mifepristone regimen on endometrium in the rhesus monkey by endometrial staging and analysis of molecular markers of endometrial receptivity. DESIGN:A prospective, randomized comparative study. SETTING:Academic research environment. ANIMAL(S):Normally cycling rhesus (...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(00)00551-3
更新日期：2000-07-01 00:00:00
abstract：OBJECTIVE:To investigate whether the antiprogestin RU486 acts primarily on the hypothalamus to delay the midcycle gonadotropin surge and thus gain insight into the site(s) of action of P in the control of ovulation. DESIGN:Prospective, crossover, single-blinded clinical study. SETTING:Outpatient clinic in an academic...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(16)56811-3
更新日期：1994-07-01 00:00:00
abstract：OBJECTIVE:To compare the effectiveness and safety of the Filshie Clip and Tubal Ring systems when applied via minilaparotomy and laparoscopy. DESIGN:Prospective, multicenter randomized controlled clinical trial, with postoperative evaluation by a physician who was masked to the operative technique. SETTING:Healthy vo...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0015-0282(00)00696-8
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVE:To assess the minimal effective dose of a GnRH antagonist (Cetrorelix; Asta Medical; Frankfurt, Germany) to prevent premature LH surge in patients undergoing controlled ovarian hyperstimulation (COH) for assisted reproductive technologies. DESIGN:In 69 patients COH was carried out with the association of hMG...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)81407-0
更新日期：1997-05-01 00:00:00
abstract：OBJECTIVE:To present an unusual side effect of therapy for adolescent menorrhagia, with commentary on management options. DESIGN:Case report. SETTING:Tertiary gynecologic center. PATIENT(S):A 13-year-old girl presenting with profuse uterine bleeding. INTERVENTION(S):Dysfunctional uterine bleeding was diagnosed, and...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.07.997
更新日期：2009-11-01 00:00:00
abstract：:The dietary, behavioral and in vitro methods of sex selection are evaluated for physicians to advise patients who desire to plan the gender of their families, but for whom chorionic villus sampling and elective abortion is unacceptable. A diet based on high potassium and sodium, and low magnesium and calcium for coup...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60000-6
更新日期：1988-07-01 00:00:00
abstract：OBJECTIVE:To report the inheritance of a pericentric inversion in chromosome 7 through the three progenies, congenital hydronephrosis, and recurrent miscarriages in an extended family. DESIGN:Case report. SETTING:Medical Faculty of Cukurova University in Turkey. PATIENT(S):Referred by obstetrics and gynecology clini...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.02.030
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVE:To quantify cytoplasmic maturity on the basis of intracytoplasmic sperm injection (ICSI) injection funnel manifestation and to evaluate influence factors of the latter. DESIGN:Prospective study. SETTING:Private fertility center. PATIENT(S):A total of 31 patients with good ovarian response. INTERVENTION(S)...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2016.06.015
更新日期：2016-10-01 00:00:00
abstract：:This retrospective cohort study compared blastocyst transfers in 136 fresh oocyte donor cycles and 69 autologous cycles using blastocysts derived from culture of thawed bipronuclear oocytes, all with oocytes derived from patients or donors less than 35 years old. The autologous cycles and oocyte donor cycles had simil...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.07.966
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVE:To report a live birth after the transfer of a single blastocyst derived from a human oocyte cryopreserved for 5 years. DESIGN:Case report. SETTING:Private assisted reproduction center. PATIENT(S):A 39-year-old woman with tubal infertility and her partner with male-related infertility. INTERVENTION(S):Ooc...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.01.106
更新日期：2008-11-01 00:00:00
abstract：:With advances in cancer therapies, survival rates in prepubescent patients have steadily increased. However, a number of these surviving patients have been rendered sterile owing to their rigorous oncologic treatment regimens. In addition to cancer treatments, men and women, who are genetically fertile, can become inf...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2013.11.025
更新日期：2014-01-01 00:00:00
abstract：:The effect of administration of a superactive and long-acting analog of luteinizing hormone-releasing hormone (LH-RH), D-Trp6-LH-RH, in doses of 0.05 or 1 microgram/day for 10 days on the hypothalamic-pituitary-gonadal axis was studied in immature female rats. Treatment with a 0.05-microgram dose of analog produced fe...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)44061-6
更新日期：1979-06-01 00:00:00
abstract：OBJECTIVE:To describe a clinical approach to and outcomes of IVF in reproductive-aged cancer survivors receiving targeted cancer therapies. DESIGN:Case report. SETTING:Not applicable. PATIENT(S):The first case is of a female patient with metastatic lung cancer receiving long-term crizotinib, an anaplastic lymphoma k...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2016.08.011
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVE:To investigate hypoestrogenic "inactive phases" (IP) in the follicular phase of the menstrual cycle, with respect to age, reproductive stage, and follicular depletion. DESIGN:Analysis of prospectively collected menstrual bleed and estrone-3-glucuronide data. SETTING:Center for Population and Health, Georget...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2012.07.1101
更新日期：2012-11-01 00:00:00
abstract：:It is suggested that heparin given in the peri-implantation period may improve clinical outcomes in women undergoing assisted reproduction techniques (ART). This systematic review evaluates the use of heparin in subfertile women undergoing ART. ...
journal_title：Fertility and sterility
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.fertnstert.2014.09.005
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:To investigate changes in menstrual cycle hormones and endometrial maturation that may contribute to the decline in fertility with aging. DESIGN:Prospective controlled clinical study. SETTING:Normal human volunteers in an academic research institution. SUBJECTS:Women with regular menstrual cycles. INTERVE...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the predictive value of seminal inhibin B and anti-Müllerian hormone (AMH) on the outcome of testicular sperm extraction (TESE) in patients with nonobstructive azoospermia. DESIGN:Prospective study. SETTING:Reproductive biology department. PATIENT(S):Forty-seven normospermic, 28 oligozoospermic...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.03.032
更新日期：2008-02-01 00:00:00
abstract：OBJECTIVE:To evaluate whether overweight and obesity are related to changes in serum sex hormone concentrations and semen quality. DESIGN:Cross-sectional study. SETTING:Data from five previous population-based environmental studies of semen quality were combined into one database at a university hospital in Denmark. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.07.1292
更新日期：2008-09-01 00:00:00
abstract：:Twelve patients with amenorrhea-galactorrhea and hyperprolactinemia are presented. The mean serum prolactin level was 175 ng/ml (range, 37 to 575 ng/ml). Basal gonadotropin levels were normal in all patients. Serum estradiol levels were normal in three women and reduced in nine. The response to luteinizing hormone-rel...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)42910-9
更新日期：1977-11-01 00:00:00
abstract：OBJECTIVE:To report the case of a patient submitted to laparoscopic bowel resection in whom histology revealed endometriosis and schistosomiasis. DESIGN:Case report. SETTING:Multidisciplinary group practice and teaching hospital. PATIENT(S):A 31-year-old patient with pelvic pain. INTERVENTION(S):Laparoscopic bowel ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.08.068
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:To determine the prevalence of anticardiolipin and antiphophatidylserine antibodies in an IVF population and to correlate their presence and specific isotype with IVF cycle outcome. DESIGN:Retrospective clinical study using stored midfollicular sera for determination of antibody status. SETTING:University h...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)81519-1
更新日期：1997-08-01 00:00:00
abstract：:Elevated endometrial antibody titers were detected in serum and peritoneal fluid of rabbits with experimentally induced endometriosis. Surgical extirpation of implants or suppression with gonadotropin-releasing hormone agonist resulted in decreased endometrial antibody titers, whereas the antibody titers in untreated ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60802-6
更新日期：1989-07-01 00:00:00
abstract：OBJECTIVE:To compare oocyte maturation, fertilization and cleavage rates, and embryonic developmental quality after culture of human immature oocytes from polycystic ovary syndrome (PCOS) patients in human tubal fluid (HTF) or tissue culture medium (TCM) 199. DESIGN:Prospective, randomized, controlled trial. SETTING:...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2007.11.082
更新日期：2009-02-01 00:00:00
abstract：:Antiphospholipid syndrome patients with recurrent miscarriage have an impairment in fibrinolysis demonstrated by prolonged clot lysis time (CLT) that cannot be attributed to differences in thrombin activatable fibrinolysis inhibitor (TAFI) antigen levels. Patients with unexplained recurrent miscarriage have an impairm...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.02.032
更新日期：2010-11-01 00:00:00
abstract：:The initial experience with the use of a portable infusion pump for the delivery of human menopausal gonadotropins (hMG) in the therapy of ovulation dysfunction of women who failed to conceive following (1) either clomiphene citrate (five patients with polycystic ovary syndrome) or danazol (three patients with mild en...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)47352-8
更新日期：1983-10-01 00:00:00
abstract：OBJECTIVE:To compare the ability of peripheral blood monocytes (PBM) and peritoneal macrophages (PM) to mediate the in vitro cytolysis of endometrial cells from eutopic and ectopic endometrium in women with endometriosis. DESIGN:Prospective study of immune function. SETTING:Institute for the Study and Treatment of En...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00062-4
更新日期：1998-06-01 00:00:00
abstract：:Hormone patterns during 113 nonconceptual gonadotropin-induced cycles of 65 infertile anovulatory women were analyzed. All but one women ovulated, i.e., the ovulation rate was 98%. Signs of defective corpus luteum function were observed during 8 cycles, and anovulation occurred in 11 treatment cycles. The duration of ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)47115-3
更新日期：1983-06-01 00:00:00
abstract：OBJECTIVE:To compare final embryo disposition between patients and donor oocyte recipients. DESIGN:Retrospective study. SETTING:Private infertility practice. PATIENT(S):Patients undergoing IVF with embryo cryopreservation. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Final cryopreserved embryo disposition. RESUL...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.08.002
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:To characterize and localize interleukin (IL)-1alpha and IL-1beta in human sperm cells. DESIGN:Prospective and comparative study. SETTING:Andrology clinic of a university hospital. PATIENT(S):Two groups of normogonadotropic men: 17 fertile men (donors with proved fertility) and 8 oligoteratoasthenospermic ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(00)00499-4
更新日期：2000-06-01 00:00:00
