Embryo disposition: choices made by patients and donor oocyte recipients.

Abstract:

OBJECTIVE:To compare final embryo disposition between patients and donor oocyte recipients. DESIGN:Retrospective study. SETTING:Private infertility practice. PATIENT(S):Patients undergoing IVF with embryo cryopreservation. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Final cryopreserved embryo disposition. RESULT(S):A total of 1,262 patients using autologous oocytes had 5,417 embryos cryopreserved. A majority either used their embryos (39%) or continued storage (35%). Of 364 patients, who did not use their remaining 1,406 embryos, 77 (21%) donated 290 embryos to other infertile couples, 41 (11%) donated 160 embryos for research, and 246 (68%) discarded 956 embryos. Concurrently, 272 donor oocyte recipients had 1,233 embryos cryopreserved. A majority either used their embryos (40%) or continued storage (23%). Of 110 recipients that did not use their remaining 455 embryos, 62 (56%) donated 280 embryos to other infertile couples, 6 (6%) donated 31 embryos for research, and 42 (38%) discarded 144 embryos. CONCLUSION(S):In our patient population, a higher proportion of patients with infertility ultimately used or stored their cryopreserved embryos for future reproduction compared with donor oocyte recipients. However, recipients were much more likely to donate to other infertile couples and less likely to discard their remaining embryos compared with patients.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Hill GA,Freeman MR

doi

10.1016/j.fertnstert.2010.08.002

subject

Has Abstract

pub_date

2011-03-01 00:00:00

pages

940-3

issue

3

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(10)02223-5

journal_volume

95

pub_type

杂志文章
  • Effect of abnormal hypo-osmotic swelling test on fertilization rate and pregnancy outcome in in vitro fertilization cycles.

    abstract:OBJECTIVE:To assess the value of the hypo-osmotic swelling test in predicting fertilization, pregnancy, implantation, miscarriage, and live birth rates in IVF-ET cycles. DESIGN:Prospective study. SETTING:Academic tertiary referral center for fertility treatment. PATIENTS:Three hundred twenty-six couples having IVF-E...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)58511-2

    authors: Biljan MM,Buckett WM,Taylor CT,Luckas M,Aird I,Kingsland CR,Lewis-Jones DI

    更新日期:1996-09-01 00:00:00

  • Preimplantation genetic diagnosis does not increase pregnancy rates in patients at risk for aneuploidy.

    abstract:OBJECTIVE:To investigate the use of preimplantation genetic diagnosis (PGD) as a method for increasing pregnancy success rates in patients at high risk for aneuploidy. DESIGN:Literature review and discussion of current evidence. CONCLUSION(S):Preimplantation genetic diagnosis selects euploid embryos for transfer in a...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2005.06.045

    authors: Shahine LK,Cedars MI

    更新日期:2006-01-01 00:00:00

  • Detection of implantation-related cytokines in cervicovaginal secretions and peripheral blood of fertile women during ovulatory menstrual cycles.

    abstract:OBJECTIVE:To determine whether cytokines implicated in uterine receptivity are detectable in cervicovaginal secretions and/or serum of fertile women, and whether their concentrations undergo hormonal regulation during the menstrual cycle. DESIGN:Prospective, observational study. SETTING:Academic medical center. PATI...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2004.03.039

    authors: Gargiulo AR,Fichorova RN,Politch JA,Hill JA,Anderson DJ

    更新日期:2004-10-01 00:00:00

  • Echographic study of follicular maturation and ovulation during the normal menstrual cycle.

    abstract::Follicular development was followed by echography during 18 menstrual cycles in 10 women volunteers. Results were correlated with changes in serum hormone levels, basal body temperature curves, and cervical mucus changes. The average follicular growth as measured from the time of echographic visualization was 0.3 cm/d...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)44592-9

    authors: Renaud RL,Macler J,Dervain I,Ehret MC,Aron C,Plas-Roser S,Spira A,Pollack H

    更新日期:1980-03-01 00:00:00

  • Current understanding of somatic stem cells in leiomyoma formation.

    abstract:OBJECTIVE:To provide a detailed summary of current scientific knowledge of somatic stem cells (SSCs) in murine and human myometrium and their putative implication in leiomyoma formation, as well as to establish new therapeutic options. DESIGN:Pubmed and Scholar One manuscripts were used to identify the most relevant s...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2014.04.051

    authors: Mas A,Cervello I,Gil-Sanchis C,Simón C

    更新日期:2014-09-01 00:00:00

  • Increased antimüllerian hormone levels and other reproductive endocrine changes in adult male relatives of women with polycystic ovary syndrome.

    abstract:OBJECTIVE:To investigate for differences in reproductive hormone levels in male relatives of women with polycystic ovary syndrome (PCOS). DESIGN:Cross-sectional study. SETTING:Academic medical center. PATIENT(S):Sixty-three fathers and 66 brothers of women with PCOS as well as two groups of control men of comparable...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2016.03.029

    authors: Torchen LC,Kumar A,Kalra B,Savjani G,Sisk R,Legro RS,Dunaif A

    更新日期:2016-07-01 00:00:00

  • A modified embryo cryopreservation method increases post-thaw survival with a concomitant increase in implantation.

    abstract:OBJECTIVE:To achieve maximum post-thaw survival of frozen embryos. DESIGN:Historical controlled study. SETTING:Hospital-based fertility center. PATIENT(S):One hundred forty-five patients whose embryos were frozen and thawed according to the standard method, and 56 patients whose embryos were frozen and thawed accord...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2005.04.054

    authors: Kattera S,Chen C

    更新日期:2005-11-01 00:00:00

  • A prospective, randomized study comparing laparoscopic ovarian cystectomy versus fenestration and coagulation in patients with endometriomas.

    abstract:OBJECTIVE:To determine the difference between two laparoscopic methods for the management of endometriomas with regard to recurrence of signs and symptoms and pregnancy rate. DESIGN:Prospective, randomized clinical trial. SETTING:Infertility and gynecologic endoscopy units of two medical university hospitals. PATIEN...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.fertnstert.2004.04.067

    authors: Alborzi S,Momtahan M,Parsanezhad ME,Dehbashi S,Zolghadri J,Alborzi S

    更新日期:2004-12-01 00:00:00

  • Gonadal structures in a fetus with complete androgen insensitivity syndrome and persistent Müllerian derivatives: comparison with normal fetal development.

    abstract:OBJECTIVE:To report a case of complete androgen insensitivity syndrome (CAIS) with Müllerian duct persistence. DESIGN:Case report. SETTING:Academic hospital. PATIENT(S):A case of CAIS at 20 weeks' gestational age, and three male and one female 20-week-old fetuses for comparison. INTERVENTION(S):DNA screening for an...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2010.09.028

    authors: Corbetta S,Muzza M,Avagliano L,Bulfamante G,Gaetti L,Eller-Vainicher C,Beck-Peccoz P,Spada A

    更新日期:2011-03-01 00:00:00

  • Using semen flow cytometry to evaluate association of ploidy status and chromatin condensation of spermatozoa with conventional semen parameters: clinical application in intrauterine insemination.

    abstract:OBJECTIVE:To evaluate the association between the ploidy status and the nuclear chromatin condensation of spermatozoa with conventional semen parameters by using semen flow cytometry (SFC). The prognostic value of SFC on the successful outcome of intrauterine insemination (IUI) was examined. DESIGN:Prospective study. ...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.fertnstert.2010.05.012

    authors: Lazaros L,Kaponis A,Vartholomatos G,Hatzi E,Botsari S,Plachouras N,Makrydimas G,Zikopoulos K,Sofikitis N,Georgiou I

    更新日期:2011-01-01 00:00:00

  • Postmolar gestational trophoblastic neoplasia: beyond the traditional risk factors.

    abstract:OBJECTIVE:To investigate the slope of linear regression of postevacuation serum hCG as an independent risk factor for postmolar gestational trophoblastic neoplasia (GTN). DESIGN:Multicenter retrospective cohort study. SETTING:Academic referral health care centers. PATIENT(S):All subjects with confirmed hydatidiform ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.fertnstert.2015.06.001

    authors: Bakhtiyari M,Mirzamoradi M,Kimyaiee P,Aghaie A,Mansournia MA,Ashrafi-Vand S,Sarfjoo FS

    更新日期:2015-09-01 00:00:00

  • CYP1A1, CYP19, and GSTM1 polymorphisms increase the risk of endometriosis.

    abstract:OBJECTIVE:To investigate the possibility of genetic contribution of CYP1A1, CYP19, GSTM1, and GSTT1 polymorphisms to endometriosis. DESIGN:Genetic polymorphism analysis. SETTING:Case-control study. PATIENT(S):A group of 275 women with sporadic endometriosis was compared with a group of 346 fertile, endometriosis-fre...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(02)04817-3

    authors: Arvanitis DA,Koumantakis GE,Goumenou AG,Matalliotakis IM,Koumantakis EE,Spandidos DA

    更新日期:2003-03-01 00:00:00

  • Importance of the biopsy date in autologous endometrial cocultures for patients with multiple implantation failures.

    abstract:OBJECTIVE:To analyze the effectiveness of autologous endometrial coculture by the cycle day of the endometrial biopsy. DESIGN:Retrospective study. SETTING:University-based IVF center. PATIENT(S):Two hundred eight patients with multiple IVF failures. INTERVENTION(S):Embryos were split and randomly allocated to growt...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0015-0282(02)03134-5

    authors: Spandorfer SD,Barmat LI,Navarro J,Liu HC,Veeck L,Rosenwaks Z

    更新日期:2002-06-01 00:00:00

  • Adult somatic cells to the rescue: nuclear reprogramming and the dispensability of gonadal germ cells.

    abstract::With advances in cancer therapies, survival rates in prepubescent patients have steadily increased. However, a number of these surviving patients have been rendered sterile owing to their rigorous oncologic treatment regimens. In addition to cancer treatments, men and women, who are genetically fertile, can become inf...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2013.11.025

    authors: Easley CA 4th,Latov DR,Simerly CR,Schatten G

    更新日期:2014-01-01 00:00:00

  • Identification and treatment of men with phospholipase Cζ-defective spermatozoa.

    abstract:OBJECTIVE:To identify and treat the gamete responsible for complete fertilization failure with intracytoplasmic sperm injection (ICSI) using a newly proposed assisted gamete treatment (AGT). DESIGN:Prospective cohort study. SETTING:Center for reproductive medicine. PATIENT(S):One-hundred and fourteen couples with an...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2020.04.044

    authors: Cheung S,Xie P,Parrella A,Keating D,Rosenwaks Z,Palermo GD

    更新日期:2020-09-01 00:00:00

  • Progesterone level and progesterone/estradiol ratio on the day of hCG administration: detrimental cutoff levels and new treatment strategy.

    abstract:OBJECTIVE:To identify if there are certain cutoff levels for P and or the P/E(2) ratio on the day of hCG that would be defined as detrimental for occurrence of pregnancy in women with normal ovarian reserve undergoing cleavage-stage embryo transfer (ET). Secondarily, to determine if these same cutoffs might have the sa...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.fertnstert.2010.12.065

    authors: Elgindy EA

    更新日期:2011-04-01 00:00:00

  • Cryptorchidism concordance in monozygotic and dizygotic twin brothers, full brothers, and half-brothers.

    abstract:OBJECTIVE:To study concordance rates of cryptorchidism (undescended testis) in pairs of boys with varying family structure, to evaluate the risk contribution from the intrauterine environment and genetic factors. DESIGN:Population based study of 1,024,500 Danish boys born from January 1, 1973 to December 31, 2004. Cla...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.09.041

    authors: Jensen MS,Toft G,Thulstrup AM,Henriksen TB,Olsen J,Christensen K,Bonde JP

    更新日期:2010-01-01 00:00:00

  • Clinical evaluation of the effects of combined treatment with bromocriptine and spironolactone in two women with the polycystic ovary syndrome.

    abstract::Two women with the polycystic ovary syndrome were treated with bromocriptine (15 to 20 mg/day) in combination with spironolactone (100 mg/day). In the first woman the combined therapy induced a marked reduction of hirsutism, with ensuing ovulation and pregnancy. In the second woman, who had hyperthecosis and had been ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)45554-8

    authors: Blum I,Bruhis S,Kaufman H

    更新日期:1981-06-01 00:00:00

  • Separation efficiency of a microfluidic sperm sorter to minimize sperm DNA damage.

    abstract:OBJECTIVE:To evaluate whether microfluidic sperm sorters (MFSSs) allow effective recovery of sorted motile sperm without DNA damage compared with the centrifugation and swim-up procedure. DESIGN:Experimental laboratory study. All participants completed questionnaires regarding previous and/or current diseases, surgery...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2015.10.023

    authors: Shirota K,Yotsumoto F,Itoh H,Obama H,Hidaka N,Nakajima K,Miyamoto S

    更新日期:2016-02-01 00:00:00

  • Contrast sonography for uterine cavity assessment: a comparison of conventional two-dimensional with three-dimensional transvaginal ultrasound; a pilot study.

    abstract:OBJECTIVE:To compare conventional two- (2-D) and three-dimensional (3-D) scanning of the uterine cavity with and without saline contrast medium. DESIGN:Observational pilot study. SETTING:University-based fertility service. PATIENT(S):Ten IVF patients requiring uterine cavity assessment. INTERVENTION(S):Two-dimensio...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)58651-8

    authors: Ayida G,Kennedy S,Barlow D,Chamberlain P

    更新日期:1996-11-01 00:00:00

  • Diagnosis and prevalence of persistent chlamydia infection in infertile women: tissue culture, direct antigen detection, and serology.

    abstract::Specimens for chlamydial culture, direct fluorescent antibody (DFA) test, two enzyme immunoassays (EIA) for antigen detection, and serum for chlamydial antibodies were collected from 256 infertile women. Specimens were taken from the tubes during tuboplasty and from the cervix and endometrium during laparoscopy or tub...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Thejls H,Gnarpe J,Lundkvist O,Heimer G,Larsson G,Victor A

    更新日期:1991-02-01 00:00:00

  • Right subclinical varicocele: how to manage in infertile patients with clinical left varicocele?

    abstract::In this prospective study, we compared the results of bilateral varicocelectomy and left varicocelectomy for treatment of infertile patients with subclinical right and clinical left varicoceles with oligoasthenospermia. Because there was more improvement in semen parameters and pregnancy rate in patients who underwent...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2009.05.069

    authors: Elbendary MA,Elbadry AM

    更新日期:2009-12-01 00:00:00

  • Effect of a phosphodiesterase type 3 inhibitor in oocyte maturation medium on subsequent mouse embryo development.

    abstract:OBJECTIVE:To investigate the effect of a phosphodiesterase type 3 inhibitor in oocyte maturation medium on subsequent embryo development. DESIGN:Animal study. SETTING:University laboratory. ANIMAL(S):CD-1 mice. INTERVENTION(S):Immature oocytes were arrested meiotically in medium containing a specific phosphodiester...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.03.041

    authors: Jee BC,Chen HY,Chian RC

    更新日期:2009-05-01 00:00:00

  • Dienogest inhibits Toll-like receptor 4 expression induced by costimulation of lipopolysaccharide and high-mobility group box 1 in endometrial epithelial cells.

    abstract:OBJECTIVE:To investigate the effect of dienogest on the expression of Toll-like receptor (TLR) 4 in human endometrial epithelial cells. DESIGN:Prospective basic research study. SETTING:Pharmaceutical research center. PATIENT(S):None. INTERVENTION(S):Not applicable. MAIN OUTCOME MEASURE(S):TLR4 in the immortalized ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.09.040

    authors: Mita S,Shimizu Y,Notsu T,Imada K,Kyo S

    更新日期:2011-12-01 00:00:00

  • Older first-time mothers and early postpartum depression: a prospective cohort study of women conceiving spontaneously or with assisted reproductive technologies.

    abstract:OBJECTIVE:To evaluate whether older first-time mothers (≥37 years) have higher rates of postpartum depression compared with younger first-time mothers, controlling for mode of conception and known risk factors for postpartum depression. DESIGN:Prospective cohort study. SETTING:Assisted reproductive technology (ART) c...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.fertnstert.2011.08.037

    authors: McMahon CA,Boivin J,Gibson FL,Fisher JR,Hammarberg K,Wynter K,Saunders DM

    更新日期:2011-11-01 00:00:00

  • Pregnancy after in vitro fertilization of human follicular oocytes collected from nonstimulated cycles, their culture in vitro and their transfer in a donor oocyte program.

    abstract::This study describes the results with immature human follicular oocytes harvested from unstimulated ovaries, matured in vitro, fertilized, and transferred to an agonadal recipient. Two hundred seventy immature oocytes were aspirated from 23 ovaries removed for various gynecological indications from August 1988 to Octo...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)54068-0

    authors: Cha KY,Koo JJ,Ko JJ,Choi DH,Han SY,Yoon TK

    更新日期:1991-01-01 00:00:00

  • Y chromosome microdeletions in infertile men with cryptorchidism.

    abstract:OBJECTIVE:To determine whether cryptorchidism associated with azoospermia or oligozoospermia may be due to microdeletions of the Y chromosome. DESIGN:Controlled clinical study. SETTINGS:Division of Medical Genetics and the Andrology Centre, Department of Obstetrics and Gynecology, University Medical Center, Ljubljana...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(03)00375-3

    authors: Kunej T,Zorn B,Peterlin B

    更新日期:2003-06-01 00:00:00

  • Obesity and poor reproductive outcome: the potential role of the endometrium.

    abstract:OBJECTIVE:To analyze the potential role of extraovarian factors such as endometrium in the reproductive outcome of obese patients. DESIGN:Retrospective study. SETTING:University-affiliated infertility clinic, between January 2001 and July 2005. PATIENT(S):Women undergoing a total of 2656 first ovum donation (OD) cyc...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2006.11.162

    authors: Bellver J,Melo MA,Bosch E,Serra V,Remohí J,Pellicer A

    更新日期:2007-08-01 00:00:00

  • Cryostorage of reproductive tissues in the in vitro fertilization laboratory: a committee opinion.

    abstract::This document is designed to assist in vitro fertility clinics in the management of cryopreserved reproductive tissues stored in cryogenic storage (cryostorage) tanks, based upon scientific principles and laboratory experience related to best practice for safe and reliable storage of cryopreserved reproductive tissue....

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2020.06.019

    authors: Practice Committees of the American Society for Reproductive Medicine, Society for Reproductive Biologists and Technologists, and Society for Assisted Reproductive Technology. Electronic address: asrm@asrm.org.

    更新日期:2020-09-01 00:00:00

  • A novel mutation of HOXA13 in a family with hand-foot-genital syndrome and the role of polyalanine expansions in the spectrum of Müllerian fusion anomalies.

    abstract:OBJECTIVE:To report a novel mutation found in a family with hand-foot-genital syndrome (HFGS). To characterize the genetic basis of true HFGS versus presence of non-HFGS-related uterovaginal septa. DESIGN:Case-control study. SETTING:Academic medical center. PATIENT(S):The HFGS patients and family members; women with...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2009.05.057

    authors: Jorgensen EM,Ruman JI,Doherty L,Taylor HS

    更新日期:2010-09-01 00:00:00