The Growing Evidence for the Importance of the Otoliths in Spatial Memory.

abstract：:Recording of identified neuronal network activity using genetically encoded calcium indicators (GECIs) requires labeling that is cell type-specific and bright enough for the detection of functional signals. However, specificity and strong expression are often not achievable using the same promoter. Here we present a c...

journal_title：Frontiers in neural circuits

authors： Kuhn B,Ozden I,Lampi Y,Hasan MT,Wang SS

更新日期：2012-07-31 00:00:00

abstract：:Dopaminergic (DA) neurons represent <0.01% of neurons in the human brain, but are essential for normal neurological and psychiatric function. The majority of these neurons reside in the ventral midbrain, but they exert their profound influences on brain function through projections to both the cortex and the basal gan...

journal_title：Frontiers in neural circuits

authors： Mani M,Ryan TA

更新日期：2009-06-01 00:00:00

abstract：:Serotonin (5-HT) selectively excites subpopulations of pyramidal neurons in the neocortex via activation of 5-HT2A (2A) receptors coupled to Gq subtype G-protein alpha subunits. Gq-mediated excitatory responses have been attributed primarily to suppression of potassium conductances, including those mediated by KV7 pot...

journal_title：Frontiers in neural circuits

authors： Stephens EK,Baker AL,Gulledge AT

更新日期：2018-01-18 00:00:00

abstract：:Focal cortical dysplasias (FCDs) are a common cause of brain seizures and are often associated with intractable epilepsy. Here we evaluated aberrant brain neurophysiology in an in vivo mouse model of FCD induced by neonatal freeze lesions (FLs) to the right cortical hemisphere (near S1). Linear multi-electrode arrays ...

journal_title：Frontiers in neural circuits

authors： Williams AJ,Zhou C,Sun QQ

更新日期：2016-11-10 00:00:00

abstract：:Optogenetic stimulation of the mouse cortex can be used to generate motor maps that are similar to maps derived from electrode-based stimulation. Here we present a refined set of procedures for repeated light-based motor mapping in ChR2-expressing mice implanted with a bilateral thinned-skull chronic window and a chro...

journal_title：Frontiers in neural circuits

authors： Silasi G,Boyd JD,Ledue J,Murphy TH

更新日期：2013-07-25 00:00:00

abstract：:Recent advances in imaging tools are inspiring zebrafish researchers to tackle ever more ambitious questions in the neurosciences. Behaviorally fundamental conserved neural networks can now be potentially studied using zebrafish from a brain-wide scale to molecular resolution. In this perspective, we offer a roadmap b...

journal_title：Frontiers in neural circuits

authors： Leung LC,Wang GX,Mourrain P

更新日期：2013-04-24 00:00:00

abstract：:We have carried out a Gal4 enhancer trap screen in zebrafish, and have generated 184 stable transgenic lines with interesting expression patterns throughout the nervous system. Of these, three display clear expression in the tectum, each with a distinguishable and stereotyped distribution of Gal4 expressing cells. Det...

journal_title：Frontiers in neural circuits

authors： Scott EK,Baier H

更新日期：2009-10-09 00:00:00

abstract：:The goal of sensory neuroscience is to understand how the brain creates its myriad of representations of the world, and uses these representations to produce perception and behavior. Circuits of neurons in spatially segregated regions of brain tissue have distinct functional specializations, and these regions are conn...

journal_title：Frontiers in neural circuits

authors： Zavitz E,Price NSC

更新日期：2019-01-09 00:00:00

abstract：:The central vocal pathway of the African clawed frog, Xenopus laevis, is a powerful vertebrate model to understand mechanisms underlying central pattern generation. However, fast and efficient methods of introducing exogenous genes into the neurons of adult X. laevis are currently not available. Here, we systematicall...

journal_title：Frontiers in neural circuits

authors： Yamaguchi A,Woller DJ,Rodrigues P

更新日期：2018-10-26 00:00:00

abstract：:Spike-timing dependent plasticity (STDP) is a biologically constrained unsupervised form of learning that potentiates or depresses synaptic connections based on the precise timing of pre-synaptic and post-synaptic firings. The effects of on-going STDP on the topology of evolving model neural networks were assessed in ...

journal_title：Frontiers in neural circuits

authors： Stone DB,Tesche CD

更新日期：2013-04-18 00:00:00

abstract：:Short-term synaptic plasticity (STP) sets the sensitivity of a synapse to incoming activity and determines the temporal patterns that it best transmits. In "driver" thalamocortical (TC) synaptic populations, STP is dominated by depression during stimulation from rest. However, during ongoing stimulation, lemniscal TC ...

journal_title：Frontiers in neural circuits

authors： Ferrati G,Martini FJ,Maravall M

更新日期：2016-02-23 00:00:00

abstract：:Complex spatial representations in the hippocampal formation and related cortical areas require input from the head direction system. However, a recurrent finding is that behavior apparently supported by these spatial representations does not appear to require input from generative head direction regions, i.e., latera...

journal_title：Frontiers in neural circuits

authors： Dillingham CM,Vann SD

更新日期：2019-09-13 00:00:00

abstract：:How complex natural sounds are represented by the main converging center of the auditory midbrain, the central inferior colliculus, is an open question. We applied neural discrimination to determine the variation of detailed encoding of individual vocalizations across the best frequency gradient of the central inferio...

journal_title：Frontiers in neural circuits

authors： Lyzwa D,Herrmann JM,Wörgötter F

更新日期：2016-02-01 00:00:00

abstract：:Mitral and tufted cells (MTCs) of the mammalian olfactory bulb are connected via dendrodendritic synapses with inhibitory interneurons in the external plexiform layer. The range, spatial layout, and temporal properties of inhibitory interactions between MTCs mediated by inhibitory interneurons remain unclear. Therefor...

journal_title：Frontiers in neural circuits

authors： Lehmann A,D'Errico A,Vogel M,Spors H

更新日期：2016-03-22 00:00:00

abstract：:"Dye-coupling", whole-mount immunohistochemistry for gap junction channel protein connexin 35 (Cx35), and freeze-fracture replica immunogold labeling (FRIL) reveal an abundance of electrical synapses/gap junctions at glutamatergic mixed synapses in the 14th spinal segment that innervates the adult male gonopodium of W...

journal_title：Frontiers in neural circuits

authors： Serrano-Velez JL,Rodriguez-Alvarado M,Torres-Vazquez II,Fraser SE,Yasumura T,Vanderpool KG,Rash JE,Rosa-Molinar E

更新日期：2014-06-26 00:00:00

abstract：:Every higher-order association cortex receives a variety of synaptic signals from different regions of the brain. How these cortical networks are capable of differentially responding to these various extrinsic synaptic inputs remains unclear. To address this issue, we studied how the basolateral amygdala (BLA) and the...

journal_title：Frontiers in neural circuits

authors： Luna VM,Morozov A

更新日期：2012-09-19 00:00:00

abstract：:Since the discovery of grid cells in rat entorhinal cortex, many models of their hexagonally arrayed spatial firing fields have been suggested. We review the models and organize them according to the mechanisms they use to encode position, update the positional code, read it out in the spatial grid pattern, and learn ...

journal_title：Frontiers in neural circuits

authors： Zilli EA

更新日期：2012-04-18 00:00:00

abstract：:The olfactory system has a unique capacity for recovery from peripheral damage. After injury to the olfactory epithelium (OE), olfactory sensory neurons (OSNs) regenerate and re-converge on target glomeruli of the olfactory bulb (OB). Thus far, this process has been described anatomically for only a few defined popula...

journal_title：Frontiers in neural circuits

authors： Cheung MC,Jang W,Schwob JE,Wachowiak M

更新日期：2014-01-07 00:00:00

abstract：:In the mammalian central nervous system, most sensory information passes through primary sensory thalamic nuclei, however the consequence of this remains unclear. Various propositions exist, likening the thalamus to a gate, or a high pass filter. Here, using a simple leaky integrate and fire model based on physiologic...

journal_title：Frontiers in neural circuits

authors： Connelly WM,Laing M,Errington AC,Crunelli V

更新日期：2016-01-14 00:00:00

abstract：:The most typical and well known inhibitory action in the cortical microcircuit is a strong inhibition on the target neuron by axo-somatic synapses. However, it has become clear that synaptic inhibition in the cortex is much more diverse and complicated. Firstly, at least ten or more inhibitory non-pyramidal cell subty...

journal_title：Frontiers in neural circuits

authors： Kubota Y,Karube F,Nomura M,Kawaguchi Y

更新日期：2016-04-25 00:00:00

abstract：:The integration of the visual stimulus takes place at the level of the neocortex, organized in anatomically distinct and functionally unique areas. Primates, including humans, are heavily dependent on vision, with approximately 50% of their neocortical surface dedicated to visual processing and possess many more visua...

journal_title：Frontiers in neural circuits

authors： Homman-Ludiye J,Bourne JA

更新日期：2014-07-04 00:00:00

abstract：:Multiple components of "γ-oscillations" between 30-170 Hz in the CA1 region of the hippocampus have been described, based on their coherence with oscillations in other brain regions and on their cross-frequency coupling with local θ-oscillations. However, it remains unclear whether the different sub-bands are generate...

journal_title：Frontiers in neural circuits

authors： Balakrishnan S,Pearce RA

更新日期：2015-01-12 00:00:00

abstract：:Neuronal activity is dominated by synaptic inputs from excitatory or inhibitory neural circuits. With the development of in vivo patch-clamp recording, especially in vivo voltage-clamp recording, researchers can not only directly measure neuronal activity, such as spiking responses or membrane potential dynamics, but ...

journal_title：Frontiers in neural circuits

authors： Tao C,Zhang G,Xiong Y,Zhou Y

更新日期：2015-05-22 00:00:00

abstract：:Local field potentials (LFPs) in cortex reflect synchronous fluctuations in the synaptic activity of local populations of neurons. The power of high frequency (>30 Hz) oscillations in LFPs is locked to the phase of low frequency (<30 Hz) oscillations, an effect known as phase-amplitude coupling (PAC). While PAC has be...

journal_title：Frontiers in neural circuits

authors： Esghaei M,Daliri MR,Treue S

更新日期：2015-12-22 00:00:00

abstract：BACKGROUND:Major depressive disorder (MDD) is a public health problem worldwide. There is increasing interest in using non-invasive therapies such as repetitive transcranial magnetic stimulation (rTMS) to treat MDD. However, the changes induced by rTMS on neural circuits remain poorly characterized. The present study a...

journal_title：Frontiers in neural circuits

authors： Pathak Y,Salami O,Baillet S,Li Z,Butson CR

更新日期：2016-07-29 00:00:00

abstract：:A moving visual figure may contain first-order signals defined by variation in mean luminance, as well as second-order signals defined by constant mean luminance and variation in luminance envelope, or higher-order signals that cannot be estimated by taking higher moments of the luminance distribution. Separating thes...

journal_title：Frontiers in neural circuits

authors： Aptekar JW,Keles MF,Mongeau JM,Lu PM,Frye MA,Shoemaker PA

更新日期：2014-10-31 00:00:00

abstract：:The firing rates of neurons in primate motor cortex have been related to multiple parameters of voluntary movement. This finding has been corroborated by stimulation-based studies that have mapped complex movements in rodent and primate motor cortex. However, it has been difficult to link the movement tuning of a neur...

journal_title：Frontiers in neural circuits

authors： Harrison TC,Murphy TH

更新日期：2013-01-18 00:00:00

abstract：:The ability of light to cause pain is paradoxical. The retina detects light but is devoid of nociceptors while the trigeminal sensory ganglia (TG) contain nociceptors but not photoreceptors. Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) are thought to mediate light-induced pain but...

journal_title：Frontiers in neural circuits

authors： Matynia A,Nguyen E,Sun X,Blixt FW,Parikh S,Kessler J,Pérez de Sevilla Müller L,Habib S,Kim P,Wang ZZ,Rodriguez A,Charles A,Nusinowitz S,Edvinsson L,Barnes S,Brecha NC,Gorin MB

更新日期：2016-08-10 00:00:00

abstract：:In addition to their ascending pathways that originate at the receptor cells, all sensory systems are characterized by extensive descending projections. Although the size of these connections often outweighs those that carry information in the ascending auditory pathway, we still have a relatively poor understanding o...

journal_title：Frontiers in neural circuits

authors： Bajo VM,King AJ

更新日期：2013-01-03 00:00:00

abstract：:The medial part of the olfactory tubercle (OT) is a brain structure located at the interface of the reward and olfactory system. It is closely related to pheromone-rewards, natural reinforcement, addiction and many other behaviors. However, the structure of the anatomic circuitry of the medial part of the OT is still ...

journal_title：Frontiers in neural circuits

authors： Zhang Z,Zhang H,Wen P,Zhu X,Wang L,Liu Q,Wang J,He X,Wang H,Xu F

更新日期：2017-07-28 00:00:00