Input-specific excitation of olfactory cortex microcircuits.

abstract：:The nematode Caenorhabditis elegans is an ideal organism for studying neural plasticity and animal behaviors. A total of 302 neurons of a C. elegans hermaphrodite have been classified into 118 neuronal groups. This simple neural circuit provides a solid basis for understanding the mechanisms of the brains of higher an...

journal_title：Frontiers in neural circuits

authors： Sasakura H,Tsukada Y,Takagi S,Mori I

更新日期：2013-11-28 00:00:00

abstract：:The primary (S1) and secondary (S2) somatosensory cortices project to several trigeminal sensory nuclei. One putative function of these corticofugal projections is the gating of sensory transmission through the trigeminal principal nucleus (Pr5), and some have proposed that S1 and S2 project differentially to the spin...

journal_title：Frontiers in neural circuits

authors： Smith JB,Watson GD,Alloway KD,Schwarz C,Chakrabarti S

更新日期：2015-09-30 00:00:00

abstract：:The parahippocampal areas including the subiculum, pre- and parasubiculum, and notably the entorhinal cortex (EC) are intimately involved in the generation of limbic seizures in temporal lobe epilepsy. We investigated changes in the expression of 10 major GABAA receptor subunit mRNAs in subfields of the ventral hippoc...

journal_title：Frontiers in neural circuits

authors： Drexel M,Kirchmair E,Sperk G

更新日期：2013-09-18 00:00:00

abstract：:The trace amines (TAs), tryptamine, tyramine, and β-phenylethylamine, are synthesized from precursor amino acids via aromatic-L-amino acid decarboxylase (AADC). We explored their role in the neuromodulation of neonatal rat spinal cord motor circuits. We first showed that the spinal cord contains the substrates for TA ...

journal_title：Frontiers in neural circuits

authors： Gozal EA,O'Neill BE,Sawchuk MA,Zhu H,Halder M,Chou CC,Hochman S

更新日期：2014-11-07 00:00:00

abstract：:The perirhinal (PER) and entorhinal cortex (EC) receive input from the agranular insular cortex (AiP) and the subcortical lateral amygdala (LA) and the main output area is the hippocampus. Information transfer through the PER/EC network however, is not always guaranteed. It is hypothesized that this network actively r...

journal_title：Frontiers in neural circuits

authors： Willems JG,Wadman WJ,Cappaert NL

更新日期：2016-06-14 00:00:00

abstract：:In the past decade, much has been elucidated regarding the functional organization of the axonal connection of olfactory sensory neurons to olfactory bulb (OB) glomeruli. However, the manner in which projection neurons of the OB process odorant input and send this information to higher brain centers remains unclear. H...

journal_title：Frontiers in neural circuits

authors： Nagayama S,Enerva A,Fletcher ML,Masurkar AV,Igarashi KM,Mori K,Chen WR

更新日期：2010-09-23 00:00:00

abstract：:Genetic labeling of neurons with a specific response feature is an emerging technology for precise dissection of brain circuits that are functionally heterogeneous at the single-cell level. While immediate early gene mapping has been widely used for decades to identify brain regions which are activated by external sti...

journal_title：Frontiers in neural circuits

authors： Kawashima T,Okuno H,Bito H

更新日期：2014-04-23 00:00:00

abstract：:In drug users, drug-related cues alone can induce dopamine release in the dorsal striatum. Instructive cues activate inputs to the striatum from both dopaminergic and cholinergic neurons, which are thought to work together to support motor learning and motivated behaviors. Imbalances in these neuromodulatory influence...

journal_title：Frontiers in neural circuits

authors： Crittenden JR,Lacey CJ,Lee T,Bowden HA,Graybiel AM

更新日期：2014-05-28 00:00:00

abstract：:Driven by the increasing channel count of neural probes, there is much effort being directed to creating increasingly scalable electrophysiology data acquisition (DAQ) systems. However, all such systems still rely on personal computers for data storage, and thus are limited by the bandwidth and cost of the computers, ...

journal_title：Frontiers in neural circuits

authors： Kinney JP,Bernstein JG,Meyer AJ,Barber JB,Bolivar M,Newbold B,Scholvin J,Moore-Kochlacs C,Wentz CT,Kopell NJ,Boyden ES

更新日期：2015-09-01 00:00:00

abstract：:[This corrects the article on p. 33 in vol. 8, PMID: 24782714.]. ...

journal_title：Frontiers in neural circuits

authors： Noudoost B,Clark KL

更新日期：2014-12-02 00:00:00

abstract：:In this review, we provide a brief overview over the current knowledge about the role of dopamine transmission in the prefrontal cortex during learning and memory. We discuss work in humans, monkeys, rats, and birds in order to provide a basis for comparison across species that might help identify crucial features and...

journal_title：Frontiers in neural circuits

authors： Puig MV,Rose J,Schmidt R,Freund N

更新日期：2014-08-05 00:00:00

abstract：:The central vocal pathway of the African clawed frog, Xenopus laevis, is a powerful vertebrate model to understand mechanisms underlying central pattern generation. However, fast and efficient methods of introducing exogenous genes into the neurons of adult X. laevis are currently not available. Here, we systematicall...

journal_title：Frontiers in neural circuits

authors： Yamaguchi A,Woller DJ,Rodrigues P

更新日期：2018-10-26 00:00:00

abstract：:"Dye-coupling", whole-mount immunohistochemistry for gap junction channel protein connexin 35 (Cx35), and freeze-fracture replica immunogold labeling (FRIL) reveal an abundance of electrical synapses/gap junctions at glutamatergic mixed synapses in the 14th spinal segment that innervates the adult male gonopodium of W...

journal_title：Frontiers in neural circuits

authors： Serrano-Velez JL,Rodriguez-Alvarado M,Torres-Vazquez II,Fraser SE,Yasumura T,Vanderpool KG,Rash JE,Rosa-Molinar E

更新日期：2014-06-26 00:00:00

abstract：:How do local circuits in the inferior colliculus (IC) process and transform spectral and temporal sound information? Using a four-tetrode array we examined the functional properties of the IC and metrics of its micro circuitry by recording neural activity from neighboring single neurons in the cat. Spectral and tempor...

journal_title：Frontiers in neural circuits

authors： Chen C,Rodriguez FC,Read HL,Escabí MA

更新日期：2012-09-27 00:00:00

abstract：:Parental migration has caused millions of children left behind, especially in China and India. Left-behind children (LBC) have a high risk of mental disorders and may present negative life outcomes in the future. However, little is known whether there are cerebral structural alterations in LBC in relative to those wit...

journal_title：Frontiers in neural circuits

authors： Fu Y,Xiao Y,Du M,Mao C,Fu G,Yang L,Liu X,Sweeney JA,Lui S,Yan Z

更新日期：2019-05-08 00:00:00

abstract：:A fluorescent voltage sensor protein "Flare" was created from a Kv1.4 potassium channel with YFP situated to report voltage-induced conformational changes in vivo. The RNA virus Sindbis introduced Flare into neurons in the binocular region of visual cortex in rat. Injection sites were selected based on intrinsic optic...

journal_title：Frontiers in neural circuits

authors： Ahrens KF,Heider B,Lee H,Isacoff EY,Siegel RM

更新日期：2012-03-22 00:00:00

abstract：:How complex natural sounds are represented by the main converging center of the auditory midbrain, the central inferior colliculus, is an open question. We applied neural discrimination to determine the variation of detailed encoding of individual vocalizations across the best frequency gradient of the central inferio...

journal_title：Frontiers in neural circuits

authors： Lyzwa D,Herrmann JM,Wörgötter F

更新日期：2016-02-01 00:00:00

abstract：:Recording of identified neuronal network activity using genetically encoded calcium indicators (GECIs) requires labeling that is cell type-specific and bright enough for the detection of functional signals. However, specificity and strong expression are often not achievable using the same promoter. Here we present a c...

journal_title：Frontiers in neural circuits

authors： Kuhn B,Ozden I,Lampi Y,Hasan MT,Wang SS

更新日期：2012-07-31 00:00:00

abstract：:The brain contains a large diversity of unique cell types that use specific genetic programs to control development and instruct the intricate wiring of sensory, motor, and cognitive brain regions. In addition to their cellular diversity and specialized connectivity maps, each region's dedicated function is also expre...

journal_title：Frontiers in neural circuits

authors： Miterko LN,Lackey EP,Heck DH,Sillitoe RV

更新日期：2018-10-10 00:00:00

abstract：:In this study, we explore the functional role of striatal cholinergic interneurons, hereinafter referred to as tonically active neurons (TANs), via computational modeling; specifically, we investigate the mechanistic relationship between TAN activity and dopamine variations and how changes in this relationship affect ...

journal_title：Frontiers in neural circuits

authors： Kim T,Capps RA,Hamade KC,Barnett WH,Todorov DI,Latash EM,Markin SN,Rybak IA,Molkov YI

更新日期：2019-02-21 00:00:00

abstract：:A moving visual figure may contain first-order signals defined by variation in mean luminance, as well as second-order signals defined by constant mean luminance and variation in luminance envelope, or higher-order signals that cannot be estimated by taking higher moments of the luminance distribution. Separating thes...

journal_title：Frontiers in neural circuits

authors： Aptekar JW,Keles MF,Mongeau JM,Lu PM,Frye MA,Shoemaker PA

更新日期：2014-10-31 00:00:00

abstract：:Lateral neuronal interactions are known to play important roles in sensory information processing. A center-on surround-off local circuit arrangement has been shown to play a role in mediating contrast enhancement in the visual, auditory, and somatosensory systems. The lateral connectivity and the influence of those c...

journal_title：Frontiers in neural circuits

authors： Kim DH,Chang AY,McTavish TS,Patel HK,Willhite DC

更新日期：2012-05-31 00:00:00

abstract：:Water-homeostasis is a fundamental physiological process for terrestrial life. In vertebrates, thirst drives water intake, but the neuronal circuits that connect the physiology of water regulation with emotional context are poorly understood. Vasopressin (VP) is a prominent messenger in this circuit, as well as L-glut...

journal_title：Frontiers in neural circuits

authors： Zhang L,Hernández VS,Vázquez-Juárez E,Chay FK,Barrio RA

更新日期：2016-03-31 00:00:00

abstract：:Recent evidence suggests that parallel synapses from the same axonal branch onto the same dendritic branch have almost identical strength. It has been proposed that this alignment is only possible through learning rules that integrate activity over long time spans. However, learning mechanisms such as spike-timing-dep...

journal_title：Frontiers in neural circuits

authors： Hartmann C,Miner DC,Triesch J

更新日期：2016-01-13 00:00:00

abstract：:Optogenetic stimulation of the mouse cortex can be used to generate motor maps that are similar to maps derived from electrode-based stimulation. Here we present a refined set of procedures for repeated light-based motor mapping in ChR2-expressing mice implanted with a bilateral thinned-skull chronic window and a chro...

journal_title：Frontiers in neural circuits

authors： Silasi G,Boyd JD,Ledue J,Murphy TH

更新日期：2013-07-25 00:00:00

abstract：:mRNP granules at adult central synapses are postulated to regulate local mRNA translation and synapse plasticity. However, they are very poorly characterized in vivo. Here, in Drosophila olfactory synapses, we present early observations and characterization of candidate synaptic mRNP particles, one of which contains a...

journal_title：Frontiers in neural circuits

authors： Hillebrand J,Pan K,Kokaram A,Barbee S,Parker R,Ramaswami M

更新日期：2010-11-03 00:00:00

abstract：:Limbic brain regions drive goal-directed behaviors. These behaviors often require dynamic motor responses, but the functional connectome of limbic structures in the diencephalon that control locomotion is not well known. The A11 region, within the posterior diencephalon has been postulated to contribute to motor funct...

journal_title：Frontiers in neural circuits

authors： Koblinger K,Jean-Xavier C,Sharma S,Füzesi T,Young L,Eaton SEA,Kwok CHT,Bains JS,Whelan PJ

更新日期：2018-10-11 00:00:00

abstract：:The olfactory system has a unique capacity for recovery from peripheral damage. After injury to the olfactory epithelium (OE), olfactory sensory neurons (OSNs) regenerate and re-converge on target glomeruli of the olfactory bulb (OB). Thus far, this process has been described anatomically for only a few defined popula...

journal_title：Frontiers in neural circuits

authors： Cheung MC,Jang W,Schwob JE,Wachowiak M

更新日期：2014-01-07 00:00:00

abstract：:The firing rates of neurons in primate motor cortex have been related to multiple parameters of voluntary movement. This finding has been corroborated by stimulation-based studies that have mapped complex movements in rodent and primate motor cortex. However, it has been difficult to link the movement tuning of a neur...

journal_title：Frontiers in neural circuits

authors： Harrison TC,Murphy TH

更新日期：2013-01-18 00:00:00

abstract：:The human cerebral cortex is highly convoluted as convex gyri and concave sulci. In the past decades, extensive studies have consistently revealed substantial differences between gyri and sulci in terms of genetics, anatomy, morphology, axonal fiber connections, and function. Although interesting findings have been re...

journal_title：Frontiers in neural circuits

authors： Yang S,Zhao Z,Cui H,Zhang T,Zhao L,He Z,Liu H,Guo L,Liu T,Becker B,Kendrick KM,Jiang X

更新日期：2019-05-15 00:00:00