Natural Vocalizations in the Mammalian Inferior Colliculus are Broadly Encoded by a Small Number of Independent Multi-Units.

abstract：:Lateral neuronal interactions are known to play important roles in sensory information processing. A center-on surround-off local circuit arrangement has been shown to play a role in mediating contrast enhancement in the visual, auditory, and somatosensory systems. The lateral connectivity and the influence of those c...

journal_title：Frontiers in neural circuits

authors： Kim DH,Chang AY,McTavish TS,Patel HK,Willhite DC

更新日期：2012-05-31 00:00:00

abstract：:"Dye-coupling", whole-mount immunohistochemistry for gap junction channel protein connexin 35 (Cx35), and freeze-fracture replica immunogold labeling (FRIL) reveal an abundance of electrical synapses/gap junctions at glutamatergic mixed synapses in the 14th spinal segment that innervates the adult male gonopodium of W...

journal_title：Frontiers in neural circuits

authors： Serrano-Velez JL,Rodriguez-Alvarado M,Torres-Vazquez II,Fraser SE,Yasumura T,Vanderpool KG,Rash JE,Rosa-Molinar E

更新日期：2014-06-26 00:00:00

abstract：:In this study, we explore the functional role of striatal cholinergic interneurons, hereinafter referred to as tonically active neurons (TANs), via computational modeling; specifically, we investigate the mechanistic relationship between TAN activity and dopamine variations and how changes in this relationship affect ...

journal_title：Frontiers in neural circuits

authors： Kim T,Capps RA,Hamade KC,Barnett WH,Todorov DI,Latash EM,Markin SN,Rybak IA,Molkov YI

更新日期：2019-02-21 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fncir.2018.00028.]. ...

journal_title：Frontiers in neural circuits

authors： Wen TC,Lall S,Pagnotta C,Markward J,Gupta D,Ratnadurai-Giridharan S,Bucci J,Greenwald L,Klugman M,Hill NJ,Carmel JB

更新日期：2018-09-25 00:00:00

abstract：:CORTICAL GABAERGIC INTERNEURONS IN RODENTS ORIGINATE IN THREE SUBCORTICAL REGIONS: the medial ganglionic eminence (MGE), the lateral/caudal ganglionic eminence (LGE/CGE), and the preoptic area (POA). Each of these neuroepithelial precursor domains contributes different interneuron subtypes to the cortex. Neuronal NOS ...

journal_title：Frontiers in neural circuits

authors： Magno L,Oliveira MG,Mucha M,Rubin AN,Kessaris N

更新日期：2012-09-24 00:00:00

abstract：:Local field potentials (LFPs) in cortex reflect synchronous fluctuations in the synaptic activity of local populations of neurons. The power of high frequency (>30 Hz) oscillations in LFPs is locked to the phase of low frequency (<30 Hz) oscillations, an effect known as phase-amplitude coupling (PAC). While PAC has be...

journal_title：Frontiers in neural circuits

authors： Esghaei M,Daliri MR,Treue S

更新日期：2015-12-22 00:00:00

abstract：:Serotonin (5-HT) selectively excites subpopulations of pyramidal neurons in the neocortex via activation of 5-HT2A (2A) receptors coupled to Gq subtype G-protein alpha subunits. Gq-mediated excitatory responses have been attributed primarily to suppression of potassium conductances, including those mediated by KV7 pot...

journal_title：Frontiers in neural circuits

authors： Stephens EK,Baker AL,Gulledge AT

更新日期：2018-01-18 00:00:00

abstract：:Spike-timing dependent plasticity (STDP) is a biologically constrained unsupervised form of learning that potentiates or depresses synaptic connections based on the precise timing of pre-synaptic and post-synaptic firings. The effects of on-going STDP on the topology of evolving model neural networks were assessed in ...

journal_title：Frontiers in neural circuits

authors： Stone DB,Tesche CD

更新日期：2013-04-18 00:00:00

abstract：:Focal cortical dysplasias (FCDs) are a common cause of brain seizures and are often associated with intractable epilepsy. Here we evaluated aberrant brain neurophysiology in an in vivo mouse model of FCD induced by neonatal freeze lesions (FLs) to the right cortical hemisphere (near S1). Linear multi-electrode arrays ...

journal_title：Frontiers in neural circuits

authors： Williams AJ,Zhou C,Sun QQ

更新日期：2016-11-10 00:00:00

abstract：:The nematode Caenorhabditis elegans is an ideal organism for studying neural plasticity and animal behaviors. A total of 302 neurons of a C. elegans hermaphrodite have been classified into 118 neuronal groups. This simple neural circuit provides a solid basis for understanding the mechanisms of the brains of higher an...

journal_title：Frontiers in neural circuits

authors： Sasakura H,Tsukada Y,Takagi S,Mori I

更新日期：2013-11-28 00:00:00

abstract：:The assembly of neural circuits involves multiple sequential steps such as the specification of cell-types, their migration to proper brain locations, morphological and physiological differentiation, and the formation and maturation of synaptic connections. This intricate and often prolonged process is guided by elabo...

journal_title：Frontiers in neural circuits

authors： Paul A,Cai Y,Atwal GS,Huang ZJ

更新日期：2012-06-26 00:00:00

abstract：:Many studies have demonstrated that vestibular sensory input is important for spatial learning and memory. However, it has been unclear what contributions the different parts of the vestibular system - the semi-circular canals and otoliths - make to these processes. The advent of mutant otolith-deficient mice has made...

journal_title：Frontiers in neural circuits

authors： Smith PF

更新日期：2019-10-18 00:00:00

abstract：:We have made use of the δ subunit-selective allosteric modulator DS2 (4-chloro-N-[2-(2-thienyl)imidazo[1,2-a]pyridine-3-yl benzamide) to assay the contribution of δ-GABAARs to tonic and phasic conductance changes in the cerebellum, thalamus and neocortex. In cerebellar granule cells, an enhancement of the tonic conduc...

journal_title：Frontiers in neural circuits

authors： Ye Z,McGee TP,Houston CM,Brickley SG

更新日期：2013-12-23 00:00:00

abstract：:Caspase-3 is a cysteine protease that is most commonly associated with cell death. Recent studies have shown additional roles in mediating cell differentiation, cell proliferation and development of cell morphology. We investigated the role of caspase-3 in the development of chick auditory brainstem nuclei during embr...

journal_title：Frontiers in neural circuits

authors： Rotschafer SE,Allen-Sharpley MR,Cramer KS

更新日期：2016-10-24 00:00:00

abstract：:Mitral and tufted cells (MTCs) of the mammalian olfactory bulb are connected via dendrodendritic synapses with inhibitory interneurons in the external plexiform layer. The range, spatial layout, and temporal properties of inhibitory interactions between MTCs mediated by inhibitory interneurons remain unclear. Therefor...

journal_title：Frontiers in neural circuits

authors： Lehmann A,D'Errico A,Vogel M,Spors H

更新日期：2016-03-22 00:00:00

abstract：:The intracerebral local field potential (LFP) is a measure of brain activity that reflects the highly dynamic flow of information across neural networks. This is a composite signal that receives contributions from multiple neural sources, yet interpreting its nature and significance may be hindered by several confound...

journal_title：Frontiers in neural circuits

authors： Herreras O

更新日期：2016-12-15 00:00:00

abstract：:The integration of the visual stimulus takes place at the level of the neocortex, organized in anatomically distinct and functionally unique areas. Primates, including humans, are heavily dependent on vision, with approximately 50% of their neocortical surface dedicated to visual processing and possess many more visua...

journal_title：Frontiers in neural circuits

authors： Homman-Ludiye J,Bourne JA

更新日期：2014-07-04 00:00:00

abstract：:We investigate the importance of the degree of peripheral or central target differentiation for mouse auditory afferent navigation to the organ of Corti and auditory nuclei in three different mouse models: first, a mouse in which the differentiation of hair cells, but not central auditory nuclei neurons is compromised...

journal_title：Frontiers in neural circuits

authors： Elliott KL,Kersigo J,Pan N,Jahan I,Fritzsch B

更新日期：2017-04-13 00:00:00

abstract：:Research efforts over the past decades have unraveled both genetic and environmental factors, which contribute to the development of autism spectrum disorders (ASD). It is, to date, largely unknown how different underlying causes result in a common phenotype. However, the individual course of development and the diffe...

journal_title：Frontiers in neural circuits

authors： Schoen M,Asoglu H,Bauer HF,Müller HP,Abaei A,Sauer AK,Zhang R,Song TJ,Bockmann J,Kassubek J,Rasche V,Grabrucker AM,Boeckers TM

更新日期：2019-02-22 00:00:00

abstract：:The parahippocampal areas including the subiculum, pre- and parasubiculum, and notably the entorhinal cortex (EC) are intimately involved in the generation of limbic seizures in temporal lobe epilepsy. We investigated changes in the expression of 10 major GABAA receptor subunit mRNAs in subfields of the ventral hippoc...

journal_title：Frontiers in neural circuits

authors： Drexel M,Kirchmair E,Sperk G

更新日期：2013-09-18 00:00:00

abstract：:mRNP granules at adult central synapses are postulated to regulate local mRNA translation and synapse plasticity. However, they are very poorly characterized in vivo. Here, in Drosophila olfactory synapses, we present early observations and characterization of candidate synaptic mRNP particles, one of which contains a...

journal_title：Frontiers in neural circuits

authors： Hillebrand J,Pan K,Kokaram A,Barbee S,Parker R,Ramaswami M

更新日期：2010-11-03 00:00:00

abstract：:The firing rates of neurons in primate motor cortex have been related to multiple parameters of voluntary movement. This finding has been corroborated by stimulation-based studies that have mapped complex movements in rodent and primate motor cortex. However, it has been difficult to link the movement tuning of a neur...

journal_title：Frontiers in neural circuits

authors： Harrison TC,Murphy TH

更新日期：2013-01-18 00:00:00

abstract：:The olfactory system has a unique capacity for recovery from peripheral damage. After injury to the olfactory epithelium (OE), olfactory sensory neurons (OSNs) regenerate and re-converge on target glomeruli of the olfactory bulb (OB). Thus far, this process has been described anatomically for only a few defined popula...

journal_title：Frontiers in neural circuits

authors： Cheung MC,Jang W,Schwob JE,Wachowiak M

更新日期：2014-01-07 00:00:00

abstract：:Recent studies using primary neuronal cultures have revealed important roles of the microRNA pathway in the regulation of neuronal development and morphology. For example, miR-134 is involved in dendritogenesis and spine development in hippocampal neurons by regulating local mRNA translation in dendrites. The in vivo ...

journal_title：Frontiers in neural circuits

authors： Christensen M,Larsen LA,Kauppinen S,Schratt G

更新日期：2010-01-12 00:00:00

abstract：:Dopaminergic (DA) neurons represent <0.01% of neurons in the human brain, but are essential for normal neurological and psychiatric function. The majority of these neurons reside in the ventral midbrain, but they exert their profound influences on brain function through projections to both the cortex and the basal gan...

journal_title：Frontiers in neural circuits

authors： Mani M,Ryan TA

更新日期：2009-06-01 00:00:00

abstract：:Cortical sensory systems are active with rich patterns of activity during sleep and under light anesthesia. Remarkably, this activity shares many characteristics with those present when the awake brain responds to sensory stimuli. We review two specific forms of such activity: slow-wave activity (SWA) in the adult bra...

journal_title：Frontiers in neural circuits

authors： McVea DA,Murphy TH,Mohajerani MH

更新日期：2016-12-21 00:00:00

abstract：:Open-source software development has skyrocketed in part due to community tools like github.com, which allows publication of code as well as the ability to create branches and push accepted modifications back to the original repository. As the number and size of EM-based datasets increases, the connectomics community ...

journal_title：Frontiers in neural circuits

authors： Katz WT,Plaza SM

更新日期：2019-02-05 00:00:00

abstract：:Since the discovery of grid cells in rat entorhinal cortex, many models of their hexagonally arrayed spatial firing fields have been suggested. We review the models and organize them according to the mechanisms they use to encode position, update the positional code, read it out in the spatial grid pattern, and learn ...

journal_title：Frontiers in neural circuits

authors： Zilli EA

更新日期：2012-04-18 00:00:00

abstract：:Fluorescent calcium (Ca(2+)) indicator proteins (FCIPs) are promising tools for functional imaging of cellular activity in living animals. However, they have still not reached their full potential for in vivo imaging of neuronal activity due to limitations in expression levels, dynamic range, and sensitivity for repor...

journal_title：Frontiers in neural circuits

authors： Lütcke H,Murayama M,Hahn T,Margolis DJ,Astori S,Zum Alten Borgloh SM,Göbel W,Yang Y,Tang W,Kügler S,Sprengel R,Nagai T,Miyawaki A,Larkum ME,Helmchen F,Hasan MT

更新日期：2010-04-29 00:00:00

abstract：:Neuronal activity is dominated by synaptic inputs from excitatory or inhibitory neural circuits. With the development of in vivo patch-clamp recording, especially in vivo voltage-clamp recording, researchers can not only directly measure neuronal activity, such as spiking responses or membrane potential dynamics, but ...

journal_title：Frontiers in neural circuits

authors： Tao C,Zhang G,Xiong Y,Zhou Y

更新日期：2015-05-22 00:00:00