Shaping Diversity Into the Brain's Form and Function.

abstract：:We investigate the importance of the degree of peripheral or central target differentiation for mouse auditory afferent navigation to the organ of Corti and auditory nuclei in three different mouse models: first, a mouse in which the differentiation of hair cells, but not central auditory nuclei neurons is compromised...

journal_title：Frontiers in neural circuits

authors： Elliott KL,Kersigo J,Pan N,Jahan I,Fritzsch B

更新日期：2017-04-13 00:00:00

abstract：:Spike-timing dependent plasticity (STDP) is a biologically constrained unsupervised form of learning that potentiates or depresses synaptic connections based on the precise timing of pre-synaptic and post-synaptic firings. The effects of on-going STDP on the topology of evolving model neural networks were assessed in ...

journal_title：Frontiers in neural circuits

authors： Stone DB,Tesche CD

更新日期：2013-04-18 00:00:00

abstract：:In the mammalian central nervous system, most sensory information passes through primary sensory thalamic nuclei, however the consequence of this remains unclear. Various propositions exist, likening the thalamus to a gate, or a high pass filter. Here, using a simple leaky integrate and fire model based on physiologic...

journal_title：Frontiers in neural circuits

authors： Connelly WM,Laing M,Errington AC,Crunelli V

更新日期：2016-01-14 00:00:00

abstract：:CORTICAL GABAERGIC INTERNEURONS IN RODENTS ORIGINATE IN THREE SUBCORTICAL REGIONS: the medial ganglionic eminence (MGE), the lateral/caudal ganglionic eminence (LGE/CGE), and the preoptic area (POA). Each of these neuroepithelial precursor domains contributes different interneuron subtypes to the cortex. Neuronal NOS ...

journal_title：Frontiers in neural circuits

authors： Magno L,Oliveira MG,Mucha M,Rubin AN,Kessaris N

更新日期：2012-09-24 00:00:00

abstract：:"Dye-coupling", whole-mount immunohistochemistry for gap junction channel protein connexin 35 (Cx35), and freeze-fracture replica immunogold labeling (FRIL) reveal an abundance of electrical synapses/gap junctions at glutamatergic mixed synapses in the 14th spinal segment that innervates the adult male gonopodium of W...

journal_title：Frontiers in neural circuits

authors： Serrano-Velez JL,Rodriguez-Alvarado M,Torres-Vazquez II,Fraser SE,Yasumura T,Vanderpool KG,Rash JE,Rosa-Molinar E

更新日期：2014-06-26 00:00:00

abstract：:In the past decade, much has been elucidated regarding the functional organization of the axonal connection of olfactory sensory neurons to olfactory bulb (OB) glomeruli. However, the manner in which projection neurons of the OB process odorant input and send this information to higher brain centers remains unclear. H...

journal_title：Frontiers in neural circuits

authors： Nagayama S,Enerva A,Fletcher ML,Masurkar AV,Igarashi KM,Mori K,Chen WR

更新日期：2010-09-23 00:00:00

abstract：:Driven by the increasing channel count of neural probes, there is much effort being directed to creating increasingly scalable electrophysiology data acquisition (DAQ) systems. However, all such systems still rely on personal computers for data storage, and thus are limited by the bandwidth and cost of the computers, ...

journal_title：Frontiers in neural circuits

authors： Kinney JP,Bernstein JG,Meyer AJ,Barber JB,Bolivar M,Newbold B,Scholvin J,Moore-Kochlacs C,Wentz CT,Kopell NJ,Boyden ES

更新日期：2015-09-01 00:00:00

abstract：:The olfactory system has a unique capacity for recovery from peripheral damage. After injury to the olfactory epithelium (OE), olfactory sensory neurons (OSNs) regenerate and re-converge on target glomeruli of the olfactory bulb (OB). Thus far, this process has been described anatomically for only a few defined popula...

journal_title：Frontiers in neural circuits

authors： Cheung MC,Jang W,Schwob JE,Wachowiak M

更新日期：2014-01-07 00:00:00

abstract：:In this review, we provide a brief overview over the current knowledge about the role of dopamine transmission in the prefrontal cortex during learning and memory. We discuss work in humans, monkeys, rats, and birds in order to provide a basis for comparison across species that might help identify crucial features and...

journal_title：Frontiers in neural circuits

authors： Puig MV,Rose J,Schmidt R,Freund N

更新日期：2014-08-05 00:00:00

abstract：:Homeostatic regulation of REM sleep drive, as measured by an increase in the number of REM sleep transitions, plays a key role in neuronal and behavioral plasticity (i.e., learning and memory). Deficits in REM sleep homeostatic drive (RSHD) are implicated in the development of many neuropsychiatric disorders. Yet, the...

journal_title：Frontiers in neural circuits

authors： Datta S,Oliver MD

更新日期：2017-09-14 00:00:00

abstract：:The parahippocampal areas including the subiculum, pre- and parasubiculum, and notably the entorhinal cortex (EC) are intimately involved in the generation of limbic seizures in temporal lobe epilepsy. We investigated changes in the expression of 10 major GABAA receptor subunit mRNAs in subfields of the ventral hippoc...

journal_title：Frontiers in neural circuits

authors： Drexel M,Kirchmair E,Sperk G

更新日期：2013-09-18 00:00:00

abstract：:Multiple components of "γ-oscillations" between 30-170 Hz in the CA1 region of the hippocampus have been described, based on their coherence with oscillations in other brain regions and on their cross-frequency coupling with local θ-oscillations. However, it remains unclear whether the different sub-bands are generate...

journal_title：Frontiers in neural circuits

authors： Balakrishnan S,Pearce RA

更新日期：2015-01-12 00:00:00

abstract：:The ability of light to cause pain is paradoxical. The retina detects light but is devoid of nociceptors while the trigeminal sensory ganglia (TG) contain nociceptors but not photoreceptors. Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) are thought to mediate light-induced pain but...

journal_title：Frontiers in neural circuits

authors： Matynia A,Nguyen E,Sun X,Blixt FW,Parikh S,Kessler J,Pérez de Sevilla Müller L,Habib S,Kim P,Wang ZZ,Rodriguez A,Charles A,Nusinowitz S,Edvinsson L,Barnes S,Brecha NC,Gorin MB

更新日期：2016-08-10 00:00:00

abstract：:Genetic programs controlling ontogeny drive many of the essential connectivity patterns within the brain. Yet it is activity, derived from the experience of interacting with the world, that sculpts the precise circuitry of the central nervous system. Such experience-dependent plasticity has been observed throughout th...

journal_title：Frontiers in neural circuits

authors： Priebe NJ,McGee AW

更新日期：2014-10-02 00:00:00

abstract：:Fluorescent calcium (Ca(2+)) indicator proteins (FCIPs) are promising tools for functional imaging of cellular activity in living animals. However, they have still not reached their full potential for in vivo imaging of neuronal activity due to limitations in expression levels, dynamic range, and sensitivity for repor...

journal_title：Frontiers in neural circuits

authors： Lütcke H,Murayama M,Hahn T,Margolis DJ,Astori S,Zum Alten Borgloh SM,Göbel W,Yang Y,Tang W,Kügler S,Sprengel R,Nagai T,Miyawaki A,Larkum ME,Helmchen F,Hasan MT

更新日期：2010-04-29 00:00:00

abstract：:MRI has been extensively used in neurodegenerative disorders, such as Alzheimer's disease (AD), frontal-temporal dementia (FTD), mild cognitive impairment (MCI), Parkinson's disease (PD), Huntington's disease (HD) and amyotrophic lateral sclerosis (ALS). MRI is important for monitoring the neurodegenerative components...

journal_title：Frontiers in neural circuits

authors： Saar G,Koretsky AP

更新日期：2019-01-07 00:00:00

abstract：:Recently, by using a combination of two viral vectors, we developed a technique for pathway-selective and reversible synaptic transmission blockade, and successfully induced a behavioral deficit of dexterous hand movements in macaque monkeys by affecting a population of spinal interneurons. To explore the capacity of ...

journal_title：Frontiers in neural circuits

authors： Sooksawate T,Isa K,Matsui R,Kato S,Kinoshita M,Kobayashi K,Watanabe D,Kobayashi K,Isa T

更新日期：2013-10-11 00:00:00

abstract：:Serotonin (5-HT) selectively excites subpopulations of pyramidal neurons in the neocortex via activation of 5-HT2A (2A) receptors coupled to Gq subtype G-protein alpha subunits. Gq-mediated excitatory responses have been attributed primarily to suppression of potassium conductances, including those mediated by KV7 pot...

journal_title：Frontiers in neural circuits

authors： Stephens EK,Baker AL,Gulledge AT

更新日期：2018-01-18 00:00:00

abstract：:Many studies have demonstrated that vestibular sensory input is important for spatial learning and memory. However, it has been unclear what contributions the different parts of the vestibular system - the semi-circular canals and otoliths - make to these processes. The advent of mutant otolith-deficient mice has made...

journal_title：Frontiers in neural circuits

authors： Smith PF

更新日期：2019-10-18 00:00:00

abstract：:Water-homeostasis is a fundamental physiological process for terrestrial life. In vertebrates, thirst drives water intake, but the neuronal circuits that connect the physiology of water regulation with emotional context are poorly understood. Vasopressin (VP) is a prominent messenger in this circuit, as well as L-glut...

journal_title：Frontiers in neural circuits

authors： Zhang L,Hernández VS,Vázquez-Juárez E,Chay FK,Barrio RA

更新日期：2016-03-31 00:00:00

abstract：:The characterization of the subthreshold, ongoing activity in cortical neurons has been the focus of numerous studies. This activity, described as spontaneous slow waves in membrane potential, has been observed in a span of species in diverse cortical and subcortical areas. We here characterized membrane potential flu...

journal_title：Frontiers in neural circuits

authors： Yaron-Jakoubovitch A,Koch C,Segev I,Yarom Y

更新日期：2013-07-11 00:00:00

abstract：:Open-source software development has skyrocketed in part due to community tools like github.com, which allows publication of code as well as the ability to create branches and push accepted modifications back to the original repository. As the number and size of EM-based datasets increases, the connectomics community ...

journal_title：Frontiers in neural circuits

authors： Katz WT,Plaza SM

更新日期：2019-02-05 00:00:00

abstract：:The trace amines (TAs), tryptamine, tyramine, and β-phenylethylamine, are synthesized from precursor amino acids via aromatic-L-amino acid decarboxylase (AADC). We explored their role in the neuromodulation of neonatal rat spinal cord motor circuits. We first showed that the spinal cord contains the substrates for TA ...

journal_title：Frontiers in neural circuits

authors： Gozal EA,O'Neill BE,Sawchuk MA,Zhu H,Halder M,Chou CC,Hochman S

更新日期：2014-11-07 00:00:00

abstract：:Local field potentials (LFPs) in cortex reflect synchronous fluctuations in the synaptic activity of local populations of neurons. The power of high frequency (>30 Hz) oscillations in LFPs is locked to the phase of low frequency (<30 Hz) oscillations, an effect known as phase-amplitude coupling (PAC). While PAC has be...

journal_title：Frontiers in neural circuits

authors： Esghaei M,Daliri MR,Treue S

更新日期：2015-12-22 00:00:00

abstract：:The primary (S1) and secondary (S2) somatosensory cortices project to several trigeminal sensory nuclei. One putative function of these corticofugal projections is the gating of sensory transmission through the trigeminal principal nucleus (Pr5), and some have proposed that S1 and S2 project differentially to the spin...

journal_title：Frontiers in neural circuits

authors： Smith JB,Watson GD,Alloway KD,Schwarz C,Chakrabarti S

更新日期：2015-09-30 00:00:00

abstract：:Every higher-order association cortex receives a variety of synaptic signals from different regions of the brain. How these cortical networks are capable of differentially responding to these various extrinsic synaptic inputs remains unclear. To address this issue, we studied how the basolateral amygdala (BLA) and the...

journal_title：Frontiers in neural circuits

authors： Luna VM,Morozov A

更新日期：2012-09-19 00:00:00

abstract：:Acetylcholine and the activation of muscarinic receptors influence the activity of neural networks generating locomotor behavior in the mammalian spinal cord. Using electrical stimulations of the ventral commissure, we show that commissural muscarinic (CM) depolarizations could be induced in lumbar motoneurons. We pro...

journal_title：Frontiers in neural circuits

authors： Bertrand SS,Cazalets JR

更新日期：2011-11-04 00:00:00

abstract：:How complex natural sounds are represented by the main converging center of the auditory midbrain, the central inferior colliculus, is an open question. We applied neural discrimination to determine the variation of detailed encoding of individual vocalizations across the best frequency gradient of the central inferio...

journal_title：Frontiers in neural circuits

authors： Lyzwa D,Herrmann JM,Wörgötter F

更新日期：2016-02-01 00:00:00

abstract：:The medial part of the olfactory tubercle (OT) is a brain structure located at the interface of the reward and olfactory system. It is closely related to pheromone-rewards, natural reinforcement, addiction and many other behaviors. However, the structure of the anatomic circuitry of the medial part of the OT is still ...

journal_title：Frontiers in neural circuits

authors： Zhang Z,Zhang H,Wen P,Zhu X,Wang L,Liu Q,Wang J,He X,Wang H,Xu F

更新日期：2017-07-28 00:00:00

abstract：:The human cerebral cortex is highly convoluted as convex gyri and concave sulci. In the past decades, extensive studies have consistently revealed substantial differences between gyri and sulci in terms of genetics, anatomy, morphology, axonal fiber connections, and function. Although interesting findings have been re...

journal_title：Frontiers in neural circuits

authors： Yang S,Zhao Z,Cui H,Zhang T,Zhao L,He Z,Liu H,Guo L,Liu T,Becker B,Kendrick KM,Jiang X

更新日期：2019-05-15 00:00:00