Abstract:
:In the mammalian central nervous system, most sensory information passes through primary sensory thalamic nuclei, however the consequence of this remains unclear. Various propositions exist, likening the thalamus to a gate, or a high pass filter. Here, using a simple leaky integrate and fire model based on physiological parameters, we show that the thalamus behaves akin to a low pass filter. Specifically, as individual cells in the thalamus rely on consistent drive to spike, stimuli that is rapidly and continuously changing over time such that it activates sensory cells with different receptive fields are unable to drive thalamic spiking. This means that thalamic encoding is robust to sensory noise, however it induces a lag in sensory representation. Thus, the thalamus stabilizes encoding of sensory information, at the cost of response rate.
journal_name
Front Neural Circuitsjournal_title
Frontiers in neural circuitsauthors
Connelly WM,Laing M,Errington AC,Crunelli Vdoi
10.3389/fncir.2015.00089subject
Has Abstractpub_date
2016-01-14 00:00:00pages
89issn
1662-5110journal_volume
9pub_type
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