Attention Decreases Phase-Amplitude Coupling, Enhancing Stimulus Discriminability in Cortical Area MT.

abstract：:Acetylcholine and the activation of muscarinic receptors influence the activity of neural networks generating locomotor behavior in the mammalian spinal cord. Using electrical stimulations of the ventral commissure, we show that commissural muscarinic (CM) depolarizations could be induced in lumbar motoneurons. We pro...

journal_title：Frontiers in neural circuits

authors： Bertrand SS,Cazalets JR

更新日期：2011-11-04 00:00:00

abstract：:Parental migration has caused millions of children left behind, especially in China and India. Left-behind children (LBC) have a high risk of mental disorders and may present negative life outcomes in the future. However, little is known whether there are cerebral structural alterations in LBC in relative to those wit...

journal_title：Frontiers in neural circuits

authors： Fu Y,Xiao Y,Du M,Mao C,Fu G,Yang L,Liu X,Sweeney JA,Lui S,Yan Z

更新日期：2019-05-08 00:00:00

abstract：:We have made use of the δ subunit-selective allosteric modulator DS2 (4-chloro-N-[2-(2-thienyl)imidazo[1,2-a]pyridine-3-yl benzamide) to assay the contribution of δ-GABAARs to tonic and phasic conductance changes in the cerebellum, thalamus and neocortex. In cerebellar granule cells, an enhancement of the tonic conduc...

journal_title：Frontiers in neural circuits

authors： Ye Z,McGee TP,Houston CM,Brickley SG

更新日期：2013-12-23 00:00:00

abstract：:Research efforts over the past decades have unraveled both genetic and environmental factors, which contribute to the development of autism spectrum disorders (ASD). It is, to date, largely unknown how different underlying causes result in a common phenotype. However, the individual course of development and the diffe...

journal_title：Frontiers in neural circuits

authors： Schoen M,Asoglu H,Bauer HF,Müller HP,Abaei A,Sauer AK,Zhang R,Song TJ,Bockmann J,Kassubek J,Rasche V,Grabrucker AM,Boeckers TM

更新日期：2019-02-22 00:00:00

abstract：:In addition to their ascending pathways that originate at the receptor cells, all sensory systems are characterized by extensive descending projections. Although the size of these connections often outweighs those that carry information in the ascending auditory pathway, we still have a relatively poor understanding o...

journal_title：Frontiers in neural circuits

authors： Bajo VM,King AJ

更新日期：2013-01-03 00:00:00

abstract：:In drug users, drug-related cues alone can induce dopamine release in the dorsal striatum. Instructive cues activate inputs to the striatum from both dopaminergic and cholinergic neurons, which are thought to work together to support motor learning and motivated behaviors. Imbalances in these neuromodulatory influence...

journal_title：Frontiers in neural circuits

authors： Crittenden JR,Lacey CJ,Lee T,Bowden HA,Graybiel AM

更新日期：2014-05-28 00:00:00

abstract：:Lateral neuronal interactions are known to play important roles in sensory information processing. A center-on surround-off local circuit arrangement has been shown to play a role in mediating contrast enhancement in the visual, auditory, and somatosensory systems. The lateral connectivity and the influence of those c...

journal_title：Frontiers in neural circuits

authors： Kim DH,Chang AY,McTavish TS,Patel HK,Willhite DC

更新日期：2012-05-31 00:00:00

abstract：:How complex natural sounds are represented by the main converging center of the auditory midbrain, the central inferior colliculus, is an open question. We applied neural discrimination to determine the variation of detailed encoding of individual vocalizations across the best frequency gradient of the central inferio...

journal_title：Frontiers in neural circuits

authors： Lyzwa D,Herrmann JM,Wörgötter F

更新日期：2016-02-01 00:00:00

abstract：:The most typical and well known inhibitory action in the cortical microcircuit is a strong inhibition on the target neuron by axo-somatic synapses. However, it has become clear that synaptic inhibition in the cortex is much more diverse and complicated. Firstly, at least ten or more inhibitory non-pyramidal cell subty...

journal_title：Frontiers in neural circuits

authors： Kubota Y,Karube F,Nomura M,Kawaguchi Y

更新日期：2016-04-25 00:00:00

abstract：:mRNP granules at adult central synapses are postulated to regulate local mRNA translation and synapse plasticity. However, they are very poorly characterized in vivo. Here, in Drosophila olfactory synapses, we present early observations and characterization of candidate synaptic mRNP particles, one of which contains a...

journal_title：Frontiers in neural circuits

authors： Hillebrand J,Pan K,Kokaram A,Barbee S,Parker R,Ramaswami M

更新日期：2010-11-03 00:00:00

abstract：:Recording of identified neuronal network activity using genetically encoded calcium indicators (GECIs) requires labeling that is cell type-specific and bright enough for the detection of functional signals. However, specificity and strong expression are often not achievable using the same promoter. Here we present a c...

journal_title：Frontiers in neural circuits

authors： Kuhn B,Ozden I,Lampi Y,Hasan MT,Wang SS

更新日期：2012-07-31 00:00:00

abstract：:The brain contains a large diversity of unique cell types that use specific genetic programs to control development and instruct the intricate wiring of sensory, motor, and cognitive brain regions. In addition to their cellular diversity and specialized connectivity maps, each region's dedicated function is also expre...

journal_title：Frontiers in neural circuits

authors： Miterko LN,Lackey EP,Heck DH,Sillitoe RV

更新日期：2018-10-10 00:00:00

abstract：:Complex spatial representations in the hippocampal formation and related cortical areas require input from the head direction system. However, a recurrent finding is that behavior apparently supported by these spatial representations does not appear to require input from generative head direction regions, i.e., latera...

journal_title：Frontiers in neural circuits

authors： Dillingham CM,Vann SD

更新日期：2019-09-13 00:00:00

abstract：:Serotonin (5-HT) selectively excites subpopulations of pyramidal neurons in the neocortex via activation of 5-HT2A (2A) receptors coupled to Gq subtype G-protein alpha subunits. Gq-mediated excitatory responses have been attributed primarily to suppression of potassium conductances, including those mediated by KV7 pot...

journal_title：Frontiers in neural circuits

authors： Stephens EK,Baker AL,Gulledge AT

更新日期：2018-01-18 00:00:00

abstract：:The characterization of the subthreshold, ongoing activity in cortical neurons has been the focus of numerous studies. This activity, described as spontaneous slow waves in membrane potential, has been observed in a span of species in diverse cortical and subcortical areas. We here characterized membrane potential flu...

journal_title：Frontiers in neural circuits

authors： Yaron-Jakoubovitch A,Koch C,Segev I,Yarom Y

更新日期：2013-07-11 00:00:00

abstract：:Since the discovery of grid cells in rat entorhinal cortex, many models of their hexagonally arrayed spatial firing fields have been suggested. We review the models and organize them according to the mechanisms they use to encode position, update the positional code, read it out in the spatial grid pattern, and learn ...

journal_title：Frontiers in neural circuits

authors： Zilli EA

更新日期：2012-04-18 00:00:00

abstract：:Methods of functional connectivity are applied ubiquitously in studies involving non-invasive whole-brain signals, but may be not optimal for exploring the propagation of the steady-state responses, which are strong oscillatory patterns of neurodynamics evoked by periodic stimulation. In our study, we explore a functi...

journal_title：Frontiers in neural circuits

authors： Vakorin VA,Ross B,Doesburg SM,Ribary U,McIntosh AR

更新日期：2019-01-15 00:00:00

abstract：:FOXP2 is a transcription factor functionally relevant for learned vocalizations in humans and songbirds. In songbirds, FoxP2 mRNA expression in the medium spiny neurons of the basal ganglia song nucleus Area X is developmentally regulated and varies with singing conditions in different social contexts. How individual ...

journal_title：Frontiers in neural circuits

authors： Thompson CK,Schwabe F,Schoof A,Mendoza E,Gampe J,Rochefort C,Scharff C

更新日期：2013-02-28 00:00:00

abstract：:In the past decade, much has been elucidated regarding the functional organization of the axonal connection of olfactory sensory neurons to olfactory bulb (OB) glomeruli. However, the manner in which projection neurons of the OB process odorant input and send this information to higher brain centers remains unclear. H...

journal_title：Frontiers in neural circuits

authors： Nagayama S,Enerva A,Fletcher ML,Masurkar AV,Igarashi KM,Mori K,Chen WR

更新日期：2010-09-23 00:00:00

abstract：:The intracerebral local field potential (LFP) is a measure of brain activity that reflects the highly dynamic flow of information across neural networks. This is a composite signal that receives contributions from multiple neural sources, yet interpreting its nature and significance may be hindered by several confound...

journal_title：Frontiers in neural circuits

authors： Herreras O

更新日期：2016-12-15 00:00:00

abstract：:The goal of sensory neuroscience is to understand how the brain creates its myriad of representations of the world, and uses these representations to produce perception and behavior. Circuits of neurons in spatially segregated regions of brain tissue have distinct functional specializations, and these regions are conn...

journal_title：Frontiers in neural circuits

authors： Zavitz E,Price NSC

更新日期：2019-01-09 00:00:00

abstract：:Defensive behavioral responses are essential for survival in threating situations. The superior colliculus (SC) has been implicated in the generation of defensive behaviors elicited by visual, tactile and auditory stimuli. Furthermore, substantia nigra pars reticulata (SNr) neurons are known to exert a modulatory effe...

journal_title：Frontiers in neural circuits

authors： Almada RC,Genewsky AJ,Heinz DE,Kaplick PM,Coimbra NC,Wotjak CT

更新日期：2018-05-07 00:00:00

abstract：:We have carried out a Gal4 enhancer trap screen in zebrafish, and have generated 184 stable transgenic lines with interesting expression patterns throughout the nervous system. Of these, three display clear expression in the tectum, each with a distinguishable and stereotyped distribution of Gal4 expressing cells. Det...

journal_title：Frontiers in neural circuits

authors： Scott EK,Baier H

更新日期：2009-10-09 00:00:00

abstract：:Open-source software development has skyrocketed in part due to community tools like github.com, which allows publication of code as well as the ability to create branches and push accepted modifications back to the original repository. As the number and size of EM-based datasets increases, the connectomics community ...

journal_title：Frontiers in neural circuits

authors： Katz WT,Plaza SM

更新日期：2019-02-05 00:00:00

abstract：:The parahippocampal areas including the subiculum, pre- and parasubiculum, and notably the entorhinal cortex (EC) are intimately involved in the generation of limbic seizures in temporal lobe epilepsy. We investigated changes in the expression of 10 major GABAA receptor subunit mRNAs in subfields of the ventral hippoc...

journal_title：Frontiers in neural circuits

authors： Drexel M,Kirchmair E,Sperk G

更新日期：2013-09-18 00:00:00

abstract：BACKGROUND:Major depressive disorder (MDD) is a public health problem worldwide. There is increasing interest in using non-invasive therapies such as repetitive transcranial magnetic stimulation (rTMS) to treat MDD. However, the changes induced by rTMS on neural circuits remain poorly characterized. The present study a...

journal_title：Frontiers in neural circuits

authors： Pathak Y,Salami O,Baillet S,Li Z,Butson CR

更新日期：2016-07-29 00:00:00

abstract：:Cortical sensory systems are active with rich patterns of activity during sleep and under light anesthesia. Remarkably, this activity shares many characteristics with those present when the awake brain responds to sensory stimuli. We review two specific forms of such activity: slow-wave activity (SWA) in the adult bra...

journal_title：Frontiers in neural circuits

authors： McVea DA,Murphy TH,Mohajerani MH

更新日期：2016-12-21 00:00:00

abstract：:Fluorescent calcium (Ca(2+)) indicator proteins (FCIPs) are promising tools for functional imaging of cellular activity in living animals. However, they have still not reached their full potential for in vivo imaging of neuronal activity due to limitations in expression levels, dynamic range, and sensitivity for repor...

journal_title：Frontiers in neural circuits

authors： Lütcke H,Murayama M,Hahn T,Margolis DJ,Astori S,Zum Alten Borgloh SM,Göbel W,Yang Y,Tang W,Kügler S,Sprengel R,Nagai T,Miyawaki A,Larkum ME,Helmchen F,Hasan MT

更新日期：2010-04-29 00:00:00

abstract：:MRI has been extensively used in neurodegenerative disorders, such as Alzheimer's disease (AD), frontal-temporal dementia (FTD), mild cognitive impairment (MCI), Parkinson's disease (PD), Huntington's disease (HD) and amyotrophic lateral sclerosis (ALS). MRI is important for monitoring the neurodegenerative components...

journal_title：Frontiers in neural circuits

authors： Saar G,Koretsky AP

更新日期：2019-01-07 00:00:00

abstract：:Recent advances in imaging tools are inspiring zebrafish researchers to tackle ever more ambitious questions in the neurosciences. Behaviorally fundamental conserved neural networks can now be potentially studied using zebrafish from a brain-wide scale to molecular resolution. In this perspective, we offer a roadmap b...

journal_title：Frontiers in neural circuits

authors： Leung LC,Wang GX,Mourrain P

更新日期：2013-04-24 00:00:00