Multiple embryonic origins of nitric oxide synthase-expressing GABAergic neurons of the neocortex.

abstract：:The trace amines (TAs), tryptamine, tyramine, and β-phenylethylamine, are synthesized from precursor amino acids via aromatic-L-amino acid decarboxylase (AADC). We explored their role in the neuromodulation of neonatal rat spinal cord motor circuits. We first showed that the spinal cord contains the substrates for TA ...

journal_title：Frontiers in neural circuits

authors： Gozal EA,O'Neill BE,Sawchuk MA,Zhu H,Halder M,Chou CC,Hochman S

更新日期：2014-11-07 00:00:00

abstract：:The perirhinal (PER) and entorhinal cortex (EC) receive input from the agranular insular cortex (AiP) and the subcortical lateral amygdala (LA) and the main output area is the hippocampus. Information transfer through the PER/EC network however, is not always guaranteed. It is hypothesized that this network actively r...

journal_title：Frontiers in neural circuits

authors： Willems JG,Wadman WJ,Cappaert NL

更新日期：2016-06-14 00:00:00

abstract：:mRNP granules at adult central synapses are postulated to regulate local mRNA translation and synapse plasticity. However, they are very poorly characterized in vivo. Here, in Drosophila olfactory synapses, we present early observations and characterization of candidate synaptic mRNP particles, one of which contains a...

journal_title：Frontiers in neural circuits

authors： Hillebrand J,Pan K,Kokaram A,Barbee S,Parker R,Ramaswami M

更新日期：2010-11-03 00:00:00

abstract：:The nematode Caenorhabditis elegans is an ideal organism for studying neural plasticity and animal behaviors. A total of 302 neurons of a C. elegans hermaphrodite have been classified into 118 neuronal groups. This simple neural circuit provides a solid basis for understanding the mechanisms of the brains of higher an...

journal_title：Frontiers in neural circuits

authors： Sasakura H,Tsukada Y,Takagi S,Mori I

更新日期：2013-11-28 00:00:00

abstract：:In the mammalian central nervous system, most sensory information passes through primary sensory thalamic nuclei, however the consequence of this remains unclear. Various propositions exist, likening the thalamus to a gate, or a high pass filter. Here, using a simple leaky integrate and fire model based on physiologic...

journal_title：Frontiers in neural circuits

authors： Connelly WM,Laing M,Errington AC,Crunelli V

更新日期：2016-01-14 00:00:00

abstract：:Dopaminergic (DA) neurons represent <0.01% of neurons in the human brain, but are essential for normal neurological and psychiatric function. The majority of these neurons reside in the ventral midbrain, but they exert their profound influences on brain function through projections to both the cortex and the basal gan...

journal_title：Frontiers in neural circuits

authors： Mani M,Ryan TA

更新日期：2009-06-01 00:00:00

abstract：:We have made use of the δ subunit-selective allosteric modulator DS2 (4-chloro-N-[2-(2-thienyl)imidazo[1,2-a]pyridine-3-yl benzamide) to assay the contribution of δ-GABAARs to tonic and phasic conductance changes in the cerebellum, thalamus and neocortex. In cerebellar granule cells, an enhancement of the tonic conduc...

journal_title：Frontiers in neural circuits

authors： Ye Z,McGee TP,Houston CM,Brickley SG

更新日期：2013-12-23 00:00:00

abstract：:Serotonin (5-HT) selectively excites subpopulations of pyramidal neurons in the neocortex via activation of 5-HT2A (2A) receptors coupled to Gq subtype G-protein alpha subunits. Gq-mediated excitatory responses have been attributed primarily to suppression of potassium conductances, including those mediated by KV7 pot...

journal_title：Frontiers in neural circuits

authors： Stephens EK,Baker AL,Gulledge AT

更新日期：2018-01-18 00:00:00

abstract：:Short-term synaptic plasticity (STP) sets the sensitivity of a synapse to incoming activity and determines the temporal patterns that it best transmits. In "driver" thalamocortical (TC) synaptic populations, STP is dominated by depression during stimulation from rest. However, during ongoing stimulation, lemniscal TC ...

journal_title：Frontiers in neural circuits

authors： Ferrati G,Martini FJ,Maravall M

更新日期：2016-02-23 00:00:00

abstract：:Caspase-3 is a cysteine protease that is most commonly associated with cell death. Recent studies have shown additional roles in mediating cell differentiation, cell proliferation and development of cell morphology. We investigated the role of caspase-3 in the development of chick auditory brainstem nuclei during embr...

journal_title：Frontiers in neural circuits

authors： Rotschafer SE,Allen-Sharpley MR,Cramer KS

更新日期：2016-10-24 00:00:00

abstract：:We have carried out a Gal4 enhancer trap screen in zebrafish, and have generated 184 stable transgenic lines with interesting expression patterns throughout the nervous system. Of these, three display clear expression in the tectum, each with a distinguishable and stereotyped distribution of Gal4 expressing cells. Det...

journal_title：Frontiers in neural circuits

authors： Scott EK,Baier H

更新日期：2009-10-09 00:00:00

abstract：:Lateral neuronal interactions are known to play important roles in sensory information processing. A center-on surround-off local circuit arrangement has been shown to play a role in mediating contrast enhancement in the visual, auditory, and somatosensory systems. The lateral connectivity and the influence of those c...

journal_title：Frontiers in neural circuits

authors： Kim DH,Chang AY,McTavish TS,Patel HK,Willhite DC

更新日期：2012-05-31 00:00:00

abstract：:Since the discovery of grid cells in rat entorhinal cortex, many models of their hexagonally arrayed spatial firing fields have been suggested. We review the models and organize them according to the mechanisms they use to encode position, update the positional code, read it out in the spatial grid pattern, and learn ...

journal_title：Frontiers in neural circuits

authors： Zilli EA

更新日期：2012-04-18 00:00:00

abstract：:The assembly of neural circuits involves multiple sequential steps such as the specification of cell-types, their migration to proper brain locations, morphological and physiological differentiation, and the formation and maturation of synaptic connections. This intricate and often prolonged process is guided by elabo...

journal_title：Frontiers in neural circuits

authors： Paul A,Cai Y,Atwal GS,Huang ZJ

更新日期：2012-06-26 00:00:00

abstract：:Complex motor behaviors are thought to be coordinated by networks of brain nuclei that may control different elementary motor programs. Transparent zebrafish larvae offer the opportunity to analyze the functional organization of motor control networks by optical manipulations of neuronal activity during behavior. We e...

journal_title：Frontiers in neural circuits

authors： Fajardo O,Zhu P,Friedrich RW

更新日期：2013-04-17 00:00:00

abstract：:In drug users, drug-related cues alone can induce dopamine release in the dorsal striatum. Instructive cues activate inputs to the striatum from both dopaminergic and cholinergic neurons, which are thought to work together to support motor learning and motivated behaviors. Imbalances in these neuromodulatory influence...

journal_title：Frontiers in neural circuits

authors： Crittenden JR,Lacey CJ,Lee T,Bowden HA,Graybiel AM

更新日期：2014-05-28 00:00:00

abstract：:Methods of functional connectivity are applied ubiquitously in studies involving non-invasive whole-brain signals, but may be not optimal for exploring the propagation of the steady-state responses, which are strong oscillatory patterns of neurodynamics evoked by periodic stimulation. In our study, we explore a functi...

journal_title：Frontiers in neural circuits

authors： Vakorin VA,Ross B,Doesburg SM,Ribary U,McIntosh AR

更新日期：2019-01-15 00:00:00

abstract：:The olfactory system has a unique capacity for recovery from peripheral damage. After injury to the olfactory epithelium (OE), olfactory sensory neurons (OSNs) regenerate and re-converge on target glomeruli of the olfactory bulb (OB). Thus far, this process has been described anatomically for only a few defined popula...

journal_title：Frontiers in neural circuits

authors： Cheung MC,Jang W,Schwob JE,Wachowiak M

更新日期：2014-01-07 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fncir.2018.00028.]. ...

journal_title：Frontiers in neural circuits

authors： Wen TC,Lall S,Pagnotta C,Markward J,Gupta D,Ratnadurai-Giridharan S,Bucci J,Greenwald L,Klugman M,Hill NJ,Carmel JB

更新日期：2018-09-25 00:00:00

abstract：:Optogenetic stimulation of the mouse cortex can be used to generate motor maps that are similar to maps derived from electrode-based stimulation. Here we present a refined set of procedures for repeated light-based motor mapping in ChR2-expressing mice implanted with a bilateral thinned-skull chronic window and a chro...

journal_title：Frontiers in neural circuits

authors： Silasi G,Boyd JD,Ledue J,Murphy TH

更新日期：2013-07-25 00:00:00

abstract：:Limbic brain regions drive goal-directed behaviors. These behaviors often require dynamic motor responses, but the functional connectome of limbic structures in the diencephalon that control locomotion is not well known. The A11 region, within the posterior diencephalon has been postulated to contribute to motor funct...

journal_title：Frontiers in neural circuits

authors： Koblinger K,Jean-Xavier C,Sharma S,Füzesi T,Young L,Eaton SEA,Kwok CHT,Bains JS,Whelan PJ

更新日期：2018-10-11 00:00:00

abstract：:A fluorescent voltage sensor protein "Flare" was created from a Kv1.4 potassium channel with YFP situated to report voltage-induced conformational changes in vivo. The RNA virus Sindbis introduced Flare into neurons in the binocular region of visual cortex in rat. Injection sites were selected based on intrinsic optic...

journal_title：Frontiers in neural circuits

authors： Ahrens KF,Heider B,Lee H,Isacoff EY,Siegel RM

更新日期：2012-03-22 00:00:00

abstract：:Local field potentials (LFPs) in cortex reflect synchronous fluctuations in the synaptic activity of local populations of neurons. The power of high frequency (>30 Hz) oscillations in LFPs is locked to the phase of low frequency (<30 Hz) oscillations, an effect known as phase-amplitude coupling (PAC). While PAC has be...

journal_title：Frontiers in neural circuits

authors： Esghaei M,Daliri MR,Treue S

更新日期：2015-12-22 00:00:00

abstract：:Recent studies using primary neuronal cultures have revealed important roles of the microRNA pathway in the regulation of neuronal development and morphology. For example, miR-134 is involved in dendritogenesis and spine development in hippocampal neurons by regulating local mRNA translation in dendrites. The in vivo ...

journal_title：Frontiers in neural circuits

authors： Christensen M,Larsen LA,Kauppinen S,Schratt G

更新日期：2010-01-12 00:00:00

abstract：:The central vocal pathway of the African clawed frog, Xenopus laevis, is a powerful vertebrate model to understand mechanisms underlying central pattern generation. However, fast and efficient methods of introducing exogenous genes into the neurons of adult X. laevis are currently not available. Here, we systematicall...

journal_title：Frontiers in neural circuits

authors： Yamaguchi A,Woller DJ,Rodrigues P

更新日期：2018-10-26 00:00:00

abstract：:The firing rates of neurons in primate motor cortex have been related to multiple parameters of voluntary movement. This finding has been corroborated by stimulation-based studies that have mapped complex movements in rodent and primate motor cortex. However, it has been difficult to link the movement tuning of a neur...

journal_title：Frontiers in neural circuits

authors： Harrison TC,Murphy TH

更新日期：2013-01-18 00:00:00

abstract：:[This corrects the article on p. 33 in vol. 8, PMID: 24782714.]. ...

journal_title：Frontiers in neural circuits

authors： Noudoost B,Clark KL

更新日期：2014-12-02 00:00:00

abstract：:Cortical sensory systems are active with rich patterns of activity during sleep and under light anesthesia. Remarkably, this activity shares many characteristics with those present when the awake brain responds to sensory stimuli. We review two specific forms of such activity: slow-wave activity (SWA) in the adult bra...

journal_title：Frontiers in neural circuits

authors： McVea DA,Murphy TH,Mohajerani MH

更新日期：2016-12-21 00:00:00

abstract：:We investigate the importance of the degree of peripheral or central target differentiation for mouse auditory afferent navigation to the organ of Corti and auditory nuclei in three different mouse models: first, a mouse in which the differentiation of hair cells, but not central auditory nuclei neurons is compromised...

journal_title：Frontiers in neural circuits

authors： Elliott KL,Kersigo J,Pan N,Jahan I,Fritzsch B

更新日期：2017-04-13 00:00:00

abstract：:The human cerebral cortex is highly convoluted as convex gyri and concave sulci. In the past decades, extensive studies have consistently revealed substantial differences between gyri and sulci in terms of genetics, anatomy, morphology, axonal fiber connections, and function. Although interesting findings have been re...

journal_title：Frontiers in neural circuits

authors： Yang S,Zhao Z,Cui H,Zhang T,Zhao L,He Z,Liu H,Guo L,Liu T,Becker B,Kendrick KM,Jiang X

更新日期：2019-05-15 00:00:00