Method and software for using m-sequences to characterize parallel components of higher-order visual tracking behavior in Drosophila.

abstract：:Dopaminergic (DA) neurons represent <0.01% of neurons in the human brain, but are essential for normal neurological and psychiatric function. The majority of these neurons reside in the ventral midbrain, but they exert their profound influences on brain function through projections to both the cortex and the basal gan...

journal_title：Frontiers in neural circuits

authors： Mani M,Ryan TA

更新日期：2009-06-01 00:00:00

abstract：:Recently, by using a combination of two viral vectors, we developed a technique for pathway-selective and reversible synaptic transmission blockade, and successfully induced a behavioral deficit of dexterous hand movements in macaque monkeys by affecting a population of spinal interneurons. To explore the capacity of ...

journal_title：Frontiers in neural circuits

authors： Sooksawate T,Isa K,Matsui R,Kato S,Kinoshita M,Kobayashi K,Watanabe D,Kobayashi K,Isa T

更新日期：2013-10-11 00:00:00

abstract：:Limbic brain regions drive goal-directed behaviors. These behaviors often require dynamic motor responses, but the functional connectome of limbic structures in the diencephalon that control locomotion is not well known. The A11 region, within the posterior diencephalon has been postulated to contribute to motor funct...

journal_title：Frontiers in neural circuits

authors： Koblinger K,Jean-Xavier C,Sharma S,Füzesi T,Young L,Eaton SEA,Kwok CHT,Bains JS,Whelan PJ

更新日期：2018-10-11 00:00:00

abstract：:Recording of identified neuronal network activity using genetically encoded calcium indicators (GECIs) requires labeling that is cell type-specific and bright enough for the detection of functional signals. However, specificity and strong expression are often not achievable using the same promoter. Here we present a c...

journal_title：Frontiers in neural circuits

authors： Kuhn B,Ozden I,Lampi Y,Hasan MT,Wang SS

更新日期：2012-07-31 00:00:00

abstract：:Recent studies using primary neuronal cultures have revealed important roles of the microRNA pathway in the regulation of neuronal development and morphology. For example, miR-134 is involved in dendritogenesis and spine development in hippocampal neurons by regulating local mRNA translation in dendrites. The in vivo ...

journal_title：Frontiers in neural circuits

authors： Christensen M,Larsen LA,Kauppinen S,Schratt G

更新日期：2010-01-12 00:00:00

abstract：:Two-photon imaging has become a useful tool for optical monitoring of neural circuits, but it requires high laser power and serial scanning of each pixel in a sample. This results in slow imaging rates, limiting the measurements of fast signals such as neuronal activity. To improve the speed and signal-to-noise ratio ...

journal_title：Frontiers in neural circuits

authors： Watson BO,Nikolenko V,Yuste R

更新日期：2009-07-06 00:00:00

abstract：:Short-term synaptic plasticity (STP) sets the sensitivity of a synapse to incoming activity and determines the temporal patterns that it best transmits. In "driver" thalamocortical (TC) synaptic populations, STP is dominated by depression during stimulation from rest. However, during ongoing stimulation, lemniscal TC ...

journal_title：Frontiers in neural circuits

authors： Ferrati G,Martini FJ,Maravall M

更新日期：2016-02-23 00:00:00

abstract：:MRI has been extensively used in neurodegenerative disorders, such as Alzheimer's disease (AD), frontal-temporal dementia (FTD), mild cognitive impairment (MCI), Parkinson's disease (PD), Huntington's disease (HD) and amyotrophic lateral sclerosis (ALS). MRI is important for monitoring the neurodegenerative components...

journal_title：Frontiers in neural circuits

authors： Saar G,Koretsky AP

更新日期：2019-01-07 00:00:00

abstract：:The goal of sensory neuroscience is to understand how the brain creates its myriad of representations of the world, and uses these representations to produce perception and behavior. Circuits of neurons in spatially segregated regions of brain tissue have distinct functional specializations, and these regions are conn...

journal_title：Frontiers in neural circuits

authors： Zavitz E,Price NSC

更新日期：2019-01-09 00:00:00

abstract：:We investigate the importance of the degree of peripheral or central target differentiation for mouse auditory afferent navigation to the organ of Corti and auditory nuclei in three different mouse models: first, a mouse in which the differentiation of hair cells, but not central auditory nuclei neurons is compromised...

journal_title：Frontiers in neural circuits

authors： Elliott KL,Kersigo J,Pan N,Jahan I,Fritzsch B

更新日期：2017-04-13 00:00:00

abstract：:The ability of light to cause pain is paradoxical. The retina detects light but is devoid of nociceptors while the trigeminal sensory ganglia (TG) contain nociceptors but not photoreceptors. Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) are thought to mediate light-induced pain but...

journal_title：Frontiers in neural circuits

authors： Matynia A,Nguyen E,Sun X,Blixt FW,Parikh S,Kessler J,Pérez de Sevilla Müller L,Habib S,Kim P,Wang ZZ,Rodriguez A,Charles A,Nusinowitz S,Edvinsson L,Barnes S,Brecha NC,Gorin MB

更新日期：2016-08-10 00:00:00

abstract：:How complex natural sounds are represented by the main converging center of the auditory midbrain, the central inferior colliculus, is an open question. We applied neural discrimination to determine the variation of detailed encoding of individual vocalizations across the best frequency gradient of the central inferio...

journal_title：Frontiers in neural circuits

authors： Lyzwa D,Herrmann JM,Wörgötter F

更新日期：2016-02-01 00:00:00

abstract：:The parahippocampal areas including the subiculum, pre- and parasubiculum, and notably the entorhinal cortex (EC) are intimately involved in the generation of limbic seizures in temporal lobe epilepsy. We investigated changes in the expression of 10 major GABAA receptor subunit mRNAs in subfields of the ventral hippoc...

journal_title：Frontiers in neural circuits

authors： Drexel M,Kirchmair E,Sperk G

更新日期：2013-09-18 00:00:00

abstract：:Since the discovery of grid cells in rat entorhinal cortex, many models of their hexagonally arrayed spatial firing fields have been suggested. We review the models and organize them according to the mechanisms they use to encode position, update the positional code, read it out in the spatial grid pattern, and learn ...

journal_title：Frontiers in neural circuits

authors： Zilli EA

更新日期：2012-04-18 00:00:00

abstract：:Genetic labeling of neurons with a specific response feature is an emerging technology for precise dissection of brain circuits that are functionally heterogeneous at the single-cell level. While immediate early gene mapping has been widely used for decades to identify brain regions which are activated by external sti...

journal_title：Frontiers in neural circuits

authors： Kawashima T,Okuno H,Bito H

更新日期：2014-04-23 00:00:00

abstract：:Complex motor behaviors are thought to be coordinated by networks of brain nuclei that may control different elementary motor programs. Transparent zebrafish larvae offer the opportunity to analyze the functional organization of motor control networks by optical manipulations of neuronal activity during behavior. We e...

journal_title：Frontiers in neural circuits

authors： Fajardo O,Zhu P,Friedrich RW

更新日期：2013-04-17 00:00:00

abstract：:Caspase-3 is a cysteine protease that is most commonly associated with cell death. Recent studies have shown additional roles in mediating cell differentiation, cell proliferation and development of cell morphology. We investigated the role of caspase-3 in the development of chick auditory brainstem nuclei during embr...

journal_title：Frontiers in neural circuits

authors： Rotschafer SE,Allen-Sharpley MR,Cramer KS

更新日期：2016-10-24 00:00:00

abstract：:Lateral neuronal interactions are known to play important roles in sensory information processing. A center-on surround-off local circuit arrangement has been shown to play a role in mediating contrast enhancement in the visual, auditory, and somatosensory systems. The lateral connectivity and the influence of those c...

journal_title：Frontiers in neural circuits

authors： Kim DH,Chang AY,McTavish TS,Patel HK,Willhite DC

更新日期：2012-05-31 00:00:00

abstract：:Defensive behavioral responses are essential for survival in threating situations. The superior colliculus (SC) has been implicated in the generation of defensive behaviors elicited by visual, tactile and auditory stimuli. Furthermore, substantia nigra pars reticulata (SNr) neurons are known to exert a modulatory effe...

journal_title：Frontiers in neural circuits

authors： Almada RC,Genewsky AJ,Heinz DE,Kaplick PM,Coimbra NC,Wotjak CT

更新日期：2018-05-07 00:00:00

abstract：:The nematode Caenorhabditis elegans is an ideal organism for studying neural plasticity and animal behaviors. A total of 302 neurons of a C. elegans hermaphrodite have been classified into 118 neuronal groups. This simple neural circuit provides a solid basis for understanding the mechanisms of the brains of higher an...

journal_title：Frontiers in neural circuits

authors： Sasakura H,Tsukada Y,Takagi S,Mori I

更新日期：2013-11-28 00:00:00

abstract：:The human cerebral cortex is highly convoluted as convex gyri and concave sulci. In the past decades, extensive studies have consistently revealed substantial differences between gyri and sulci in terms of genetics, anatomy, morphology, axonal fiber connections, and function. Although interesting findings have been re...

journal_title：Frontiers in neural circuits

authors： Yang S,Zhao Z,Cui H,Zhang T,Zhao L,He Z,Liu H,Guo L,Liu T,Becker B,Kendrick KM,Jiang X

更新日期：2019-05-15 00:00:00

abstract：:Methods of functional connectivity are applied ubiquitously in studies involving non-invasive whole-brain signals, but may be not optimal for exploring the propagation of the steady-state responses, which are strong oscillatory patterns of neurodynamics evoked by periodic stimulation. In our study, we explore a functi...

journal_title：Frontiers in neural circuits

authors： Vakorin VA,Ross B,Doesburg SM,Ribary U,McIntosh AR

更新日期：2019-01-15 00:00:00

abstract：:In the mammalian central nervous system, most sensory information passes through primary sensory thalamic nuclei, however the consequence of this remains unclear. Various propositions exist, likening the thalamus to a gate, or a high pass filter. Here, using a simple leaky integrate and fire model based on physiologic...

journal_title：Frontiers in neural circuits

authors： Connelly WM,Laing M,Errington AC,Crunelli V

更新日期：2016-01-14 00:00:00

abstract：:In the past decade, much has been elucidated regarding the functional organization of the axonal connection of olfactory sensory neurons to olfactory bulb (OB) glomeruli. However, the manner in which projection neurons of the OB process odorant input and send this information to higher brain centers remains unclear. H...

journal_title：Frontiers in neural circuits

authors： Nagayama S,Enerva A,Fletcher ML,Masurkar AV,Igarashi KM,Mori K,Chen WR

更新日期：2010-09-23 00:00:00

abstract：:Driven by the increasing channel count of neural probes, there is much effort being directed to creating increasingly scalable electrophysiology data acquisition (DAQ) systems. However, all such systems still rely on personal computers for data storage, and thus are limited by the bandwidth and cost of the computers, ...

journal_title：Frontiers in neural circuits

authors： Kinney JP,Bernstein JG,Meyer AJ,Barber JB,Bolivar M,Newbold B,Scholvin J,Moore-Kochlacs C,Wentz CT,Kopell NJ,Boyden ES

更新日期：2015-09-01 00:00:00

abstract：:Optogenetic stimulation of the mouse cortex can be used to generate motor maps that are similar to maps derived from electrode-based stimulation. Here we present a refined set of procedures for repeated light-based motor mapping in ChR2-expressing mice implanted with a bilateral thinned-skull chronic window and a chro...

journal_title：Frontiers in neural circuits

authors： Silasi G,Boyd JD,Ledue J,Murphy TH

更新日期：2013-07-25 00:00:00

abstract：:Spike-timing dependent plasticity (STDP) is a biologically constrained unsupervised form of learning that potentiates or depresses synaptic connections based on the precise timing of pre-synaptic and post-synaptic firings. The effects of on-going STDP on the topology of evolving model neural networks were assessed in ...

journal_title：Frontiers in neural circuits

authors： Stone DB,Tesche CD

更新日期：2013-04-18 00:00:00

abstract：:In addition to their ascending pathways that originate at the receptor cells, all sensory systems are characterized by extensive descending projections. Although the size of these connections often outweighs those that carry information in the ascending auditory pathway, we still have a relatively poor understanding o...

journal_title：Frontiers in neural circuits

authors： Bajo VM,King AJ

更新日期：2013-01-03 00:00:00

abstract：:The primary (S1) and secondary (S2) somatosensory cortices project to several trigeminal sensory nuclei. One putative function of these corticofugal projections is the gating of sensory transmission through the trigeminal principal nucleus (Pr5), and some have proposed that S1 and S2 project differentially to the spin...

journal_title：Frontiers in neural circuits

authors： Smith JB,Watson GD,Alloway KD,Schwarz C,Chakrabarti S

更新日期：2015-09-30 00:00:00

abstract：:Neuronal activity is dominated by synaptic inputs from excitatory or inhibitory neural circuits. With the development of in vivo patch-clamp recording, especially in vivo voltage-clamp recording, researchers can not only directly measure neuronal activity, such as spiking responses or membrane potential dynamics, but ...

journal_title：Frontiers in neural circuits

authors： Tao C,Zhang G,Xiong Y,Zhou Y

更新日期：2015-05-22 00:00:00