Metagenomic analysis of the RNA fraction of the fecal virome indicates high diversity in pigs infected by porcine endemic diarrhea virus in the United States.

abstract：BACKGROUND:The aquatic birnavirus infectious pancreatic necrosis virus (IPNV) causes infectious pancreatic necrosis (IPN), a severe disease in farmed salmonid fish. IPNV has a very broad host range and infects many different species of fish as well as molluscs and crustaceans. Investigation of the host reservoir of a v...

journal_title：Virology journal

authors： Ørpetveit I,Küntziger T,Sindre H,Rimstad E,Dannevig BH

更新日期：2012-10-05 00:00:00

abstract：BACKGROUND:The diseases caused by Rice black streaked dwarf virus (RBSDV) and Southern rice black streaked dwarf virus (SRBSDV) have been occurring epidemically in China and southeastern Asia in recent years. A sensitive, reliable and quantitative method is required to detect and distinguish for RBSDV and SRBSDV in ric...

journal_title：Virology journal

authors： Zhang P,Mar TT,Liu W,Li L,Wang X

更新日期：2013-01-18 00:00:00

abstract：BACKGROUND:Mumps virus (MuV) is a highly infectious paramyxovirus closely related to measles virus (MeV). Despite the availability of a mumps vaccine, outbreaks continue to occur and no treatment options are available. Vitamin A and other naturally occurring retinoids inhibit the replication of MeV in vitro. METHODS:A...

journal_title：Virology journal

authors： Soye KJ,Trottier C,Di Lenardo TZ,Restori KH,Reichman L,Miller WH Jr,Ward BJ

更新日期：2013-11-14 00:00:00

abstract：BACKGROUND:Foot-and-mouth disease (FMD) is an extremely contagious viral disease of cattle, pigs, sheep, goats, and many cloven-hoofed wild animals. FMDV serotypes O and Asia 1 have circulated separately in China during the last fifty years, and eliminating infected animals and vaccination are the main policies to prev...

journal_title：Virology journal

authors： Wu L,Jiang T,Lu ZJ,Yang YM,Sun P,Liang Z,Li D,Fu YF,Cao YM,Liu XT,Liu ZX

更新日期：2011-04-23 00:00:00

abstract：:The NanoSight LM10 with Nanoparticle tracking analysis (NTA) software was evaluated for the quantification of latex particles, adenovirus 5, and influenza virus. The inter-day variability was determined by measuring the same sample over several consecutive days and the method's accuracy was demonstrated by using known...

journal_title：Virology journal

authors： Kramberger P,Ciringer M,Štrancar A,Peterka M

更新日期：2012-11-12 00:00:00

abstract：BACKGROUND:Chronic viral hepatitis B remains a global public health concern. Currently, several drugs, such as lamivudine and telbivudine, are recommended for treatment of patients with chronic hepatitis B. However, there are no conclusive results on the comparison of the efficacy of lamivudine (LAM) and telbivudine (L...

journal_title：Virology journal

authors： Zhao S,Tang L,Fan X,Chen L,Zhou R,Dai X

更新日期：2010-09-03 00:00:00

abstract：:Flaviviruses are small viruses with single-stranded RNA, which include the yellow fever virus, dengue virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, and Zika virus; and are causal agents of the most important emerging diseases that have no available treatment to date. In recent yea...

journal_title：Virology journal

authors： García LL,Padilla L,Castaño JC

更新日期：2017-05-15 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a worldwide public health burden and it is estimated that 185 million people are or have previously been infected worldwide. There is no effective vaccine for prevention of HCV infection; however, a number of drugs are available for the treatment of infection. The availability of d...

journal_title：Virology journal

authors： Jardim ACG,Shimizu JF,Rahal P,Harris M

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:In China, more than 20 million patients with chronic hepatitis B need antiviral treatment. Side effects of antiviral treatment such as renal complications can be problematic, particularly in an aging population. METHODS:The data were retrospectively extracted from the hospital medical charts of five centers...

journal_title：Virology journal

authors： Gu J,Yu G,Zhang X,Zhang S,Cai H,Ye C,Yang Y,Li D,Tong Z,Shen H,Chen H,Ding F,Lai X,Liu J,Xu M,Wu W

更新日期：2021-01-13 00:00:00

abstract：BACKGROUND:Human herpesviruses have been hypothesized as environmental triggers in the development of autoimmune thyroid diseases (AITD), and in particular active human herpesvirus 6A (HHV-6A) infection was detected in thyrocytes of Hashimoto's thyroiditis (HT) patients, who also show specific anti-viral immune respons...

journal_title：Virology journal

authors： Caselli E,D'Accolti M,Soffritti I,Zatelli MC,Rossi R,Degli Uberti E,Di Luca D

更新日期：2017-01-11 00:00:00

abstract：BACKGROUND:A number of gene therapy applications would benefit from vectors capable of expressing multiple genes. In this study we explored the feasibility and efficiency of expressing two or three transgenes in HIV-1 based lentiviral vector. Bicistronic and tricistronic self-inactivating lentiviral vectors were constr...

journal_title：Virology journal

authors： Chinnasamy D,Milsom MD,Shaffer J,Neuenfeldt J,Shaaban AF,Margison GP,Fairbairn LJ,Chinnasamy N

更新日期：2006-03-15 00:00:00

abstract：BACKGROUND:Hepatitis C virus roots a chronic liver disease. Currently approved treatment strategy includes administration of alpha interferon and ribavirin combined therapy for 24-48 weeks. One of the predictor of sustained virological response is an early virological response to treatment characterized as rapid respon...

journal_title：Virology journal

authors： Akram M,Idrees M,Hussain A,Afzal S,Ilyas M,Zafar S,Aftab M,Badar S,Khubaib B

更新日期：2011-05-23 00:00:00

abstract：BACKGROUND:Human noroviruses (NoVs) are the main cause of gastroenteritis worldwide. The most commonly detected NoV strains belong to the genetically diverse GII.4 genotype, with new pandemic variants emerging periodically. Despite extensive efforts, NoV investigation has been hampered by the lack of an effective in vi...

journal_title：Virology journal

authors： Carmona-Vicente N,Allen DJ,Rodríguez-Díaz J,Iturriza-Gómara M,Buesa J

更新日期：2016-05-21 00:00:00

abstract：BACKGROUND:Throughout the history of human influenza pandemics, pigs have been considered the most likely "mixing vessel" for reassortment between human and avian influenza viruses (AIVs). However, the replication efficiencies of influenza viruses from various hosts, as well as the expression of sialic acid (Sia) recep...

journal_title：Virology journal

authors： Van Poucke SG,Nicholls JM,Nauwynck HJ,Van Reeth K

更新日期：2010-02-16 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV) is the leading viral pathogen associated with bronchiolitis and lower respiratory tract disease in infants and young children worldwide. The respiratory epithelium is the primary initiator of pulmonary inflammation in RSV infections, which cause significant perturbations of ...

journal_title：Virology journal

authors： Zhao D,Peng D,Li L,Zhang Q,Zhang C

更新日期：2008-10-06 00:00:00

abstract：BACKGROUND:Dengue fever is perhaps the most important viral re-emergent disease especially in tropical and sub-tropical countries, affecting about 50 million people around the world yearly. In Colombia, dengue virus was first detected in 1971 and still remains as a major public health issue. Although four viral serotyp...

journal_title：Virology journal

authors： Méndez JA,Usme-Ciro JA,Domingo C,Rey GJ,Sánchez JA,Tenorio A,Gallego-Gomez JC

更新日期：2012-03-09 00:00:00

abstract：BACKGROUND:Post-transplant lymphoproliferative disorders (PTLD) are serious complications in lung transplant recipients. No consensus on EBV DNAemia levels predictive of PTLD has been reached. In addition, in many instances EBV DNAemia is determined in patients with suggestive symptoms only. METHODS:The characteristic...

journal_title：Virology journal

authors： Baldanti F,Rognoni V,Cascina A,Oggionni T,Tinelli C,Meloni F

更新日期：2011-09-05 00:00:00

abstract：BACKGROUND:The binding of viral-specific antibodies to cell-surface antigens usually results in down modulation of the antigen through redistribution of antigens into patches that subsequently may be internalized by endocytosis or may form caps that can be expelled to the extracellular space. Here, by use of confocal-l...

journal_title：Virology journal

authors： Sarmiento RE,Tirado RG,Valverde LE,Gómez-Garcia B

更新日期：2007-07-03 00:00:00

abstract：:Secondary pneumonia due to Staphylococcus aureus (S. aureus) causes significant morbidity and mortality. The aim of the research was designed a novel DNA vaccine encoding the Mycobacterium tuberculosis secreted antigen Ag85A fused with the influenza A virus (IAV) HA2 protein to provide protection against both influenz...

journal_title：Virology journal

authors： Dai J,Pei D,Wang B,Kuang Y,Ren L,Cao K,Zuo B,Shao J,Li S,Jiang Z,Li H,Li M

更新日期：2013-01-31 00:00:00

abstract：BACKGROUND:Tomato yellow leaf curl virus (TYLCV), a monopartite begomovirus (family Geminiviridae) is responsible for heavy yield losses for tomato production around the globe. In Oman at least five distinct begomoviruses cause disease in tomato, including TYLCV. Unusually, TYLCV infections in Oman are sometimes associ...

journal_title：Virology journal

authors： Ammara Ue,Mansoor S,Saeed M,Amin I,Briddon RW,Al-Sadi AM

更新日期：2015-03-04 00:00:00

abstract：BACKGROUND:Aedes aegypti is a competent arthropod vector of chikungunya virus (CHIKV). The rate at which the virus disseminate in the vector is limited by temperature of their environment which can be an important determinant of geographical and seasonal limits to transmission by the arthropods in the tropics. This stu...

journal_title：Virology journal

authors： Mbaika S,Lutomiah J,Chepkorir E,Mulwa F,Khayeka-Wandabwa C,Tigoi C,Oyoo-Okoth E,Mutisya J,Ng'ang'a Z,Sang R

更新日期：2016-06-29 00:00:00

abstract：BACKGROUND:Enzootic nasal tumor virus (ENTV) is a betaretrovirus of sheep (ENTV-1) and goats (ENTV-2) associated with neoplastic transformation of epithelial cells of the ethmoid turbinate. Confirmation of the role of ENTV in the pathogenesis of enzootic nasal adenocarcinoma (ENA) has yet to be resolved due to the inab...

journal_title：Virology journal

authors： He Y,Zhang Q,Wang J,Zhou M,Fu M,Xu X

更新日期：2017-07-26 00:00:00

abstract：BACKGROUND:To explore the relationship between enteroviruses and hospitalized children with hand, foot and mouth disease (HFMD) complicated with nervous system disease. 234 hospitalized HFMD patients treated in Shengjing Hospital, Liaoning Province were analyzed retrospectively. Based on the presence and severity of ne...

journal_title：Virology journal

authors： Xu W,Liu CF,Yan L,Li JJ,Wang LJ,Qi Y,Cheng RB,Xiong XY

更新日期：2012-01-09 00:00:00

abstract：BACKGROUND:Human enterovirus 71 (EV-71) is known of having caused numerous outbreaks of hand-foot-mouth disease, and other clinical manifestations globally. In 2008, 989 EV-71 strains were isolated in Taiwan. RESULTS:In this study, the genetic and antigenic properties of these strains were analyzed and the genetic div...

journal_title：Virology journal

authors： Huang YP,Lin TL,Hsu LC,Chen YJ,Tseng YH,Hsu CC,Fan WB,Yang JY,Chang FY,Wu HS

更新日期：2010-10-20 00:00:00

abstract：BACKGROUND:The major structural protein of coronaviruses, the membrane (M) protein, can elicit the formation of protective antibodies, but little information is available about the M protein of porcine epidemic diarrhea virus (PEDV). Identification of epitopes on the PEDV M protein will be helpful in the elucidation of...

journal_title：Virology journal

authors： Zhang Z,Chen J,Shi H,Chen X,Shi D,Feng L,Yang B

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Protease inhibitors (PIs) to treat hepatitis C (HCV) virus infection have been approved and others are under development. RESULTS:The aims of this study were to illustrate natural polymorphisms in the HCV protease and measure the frequency of PI resistance mutations in different HCV genotypes from PI-naïve ...

journal_title：Virology journal

authors： Paolucci S,Fiorina L,Piralla A,Gulminetti R,Novati S,Barbarini G,Sacchi P,Gatti M,Dossena L,Baldanti F

更新日期：2012-10-24 00:00:00

abstract：BACKGROUND:T4 phage is a model species that has contributed broadly to our understanding of molecular biology. T4 DNA replication and packaging share various mechanisms with human double-stranded DNA viruses such as herpes virus. The literature indicates that T4-like phage genomes have permuted terminal sequences, and ...

journal_title：Virology journal

authors： Jiang X,Jiang H,Li C,Wang S,Mi Z,An X,Chen J,Tong Y

更新日期：2011-04-27 00:00:00

abstract：BACKGROUND:Using a murine model of parainfluenza virus infection (mPIV1 or Sendai virus; SeV), we compared the inflammatory responses to lethal and sub-lethal infections in inbred DBA/2 mice. METHODS:Mice were intranasally inoculated with either 1.6×10(3) or 1.6×10(5) infectious units (IU) of SeV or diluent control. C...

journal_title：Virology journal

authors： Suryadevara M,Bonville CA,Rosenberg HF,Domachowske JB

更新日期：2013-12-21 00:00:00

abstract：BACKGROUND:Highly-pathogenic avian influenza (HPAI) H5N1 and Newcastle disease (ND) viruses are the two most important poultry viruses in the world, with the ability to cause classic central nervous system dysfunction in poultry and migratory birds. To elucidate the mechanisms of neurovirulence caused by these viruses,...

journal_title：Virology journal

authors： Balasubramaniam VR,Wai TH,Omar AR,Othman I,Hassan SS

更新日期：2012-02-23 00:00:00

abstract：BACKGROUND:The incidence of dengue, an infectious disease caused by dengue virus (DENV), has dramatically increased around the world in recent decades and is becoming a severe public health threat. However, there is currently no specific treatment for dengue fever, and licensed vaccine against dengue is not available. ...

journal_title：Virology journal

authors： Zhang S,Liang M,Gu W,Li C,Miao F,Wang X,Jin C,Zhang L,Zhang F,Zhang Q,Jiang L,Li M,Li D

更新日期：2011-06-30 00:00:00