Characterization of hepatitis C Virus genotype 3a hypervariable region 1 in patients achieved rapid virological response to alpha interferon and ribavirin combination therapy.

abstract：:Cyclooxygenases (COXs) play a significant role in many different viral infections with respect to replication and pathogenesis. Here we investigated the role of COXs in the mouse hepatitis coronavirus (MHV) infection cycle. Blocking COX activity by different inhibitors or by RNA interference affected MHV infection in ...

journal_title：Virology journal

authors： Raaben M,Einerhand AW,Taminiau LJ,van Houdt M,Bouma J,Raatgeep RH,Büller HA,de Haan CA,Rossen JW

更新日期：2007-06-07 00:00:00

abstract：BACKGROUND:There are over 100 known human adenovirus (HAdV) types, which are able to cause a broad variety of different self-limiting but also lethal diseases especially in immunocompromised patients. Only limited information about the pathogenesis and biology of the majority of these virus types is available. In the p...

journal_title：Virology journal

authors： Mese K,Bunz O,Schellhorn S,Volkwein W,Jung D,Gao J,Zhang W,Baiker A,Ehrhardt A

更新日期：2020-04-09 00:00:00

abstract：: Previously, we explored the epidemic pattern and molecular characterization of enteroviruses isolated in Chungnam, Korea from 2005 to 2006. The present study extended these observations to 2008 and 2009. In this study, enteroviruses showed similar seasonal prevalent pattern from summer to fall and age distribution to...

journal_title：Virology journal

authors： Baek K,Yeo S,Lee B,Park K,Song J,Yu J,Rheem I,Kim J,Hwang S,Choi Y,Cheon D,Park J

更新日期：2011-06-13 00:00:00

abstract：BACKGROUND:Porcine circovirus type-2b (PCV2b) is recognized as the etiological agent of the various clinical manifestations of porcine circovirus-associated disease (PCVAD). Previous studies have demonstrated effectiveness of chimeric PCV1-2 vaccines against PCV2b challenge. In this study, the efficacy of inactivated a...

journal_title：Virology journal

authors： Li J,Yu T,Wang X,Zhou J,Gao R,Zhang F,Gao X,Gao S,Liu X

更新日期：2015-07-30 00:00:00

abstract：BACKGROUND:Farmington virus (FARV) is a rhabdovirus that was isolated from a wild bird during an outbreak of epizootic eastern equine encephalitis on a pheasant farm in Connecticut, USA. FINDINGS:Analysis of the nearly complete genome sequence of the prototype CT AN 114 strain indicates that it encodes the five canoni...

journal_title：Virology journal

authors： Palacios G,Forrester NL,Savji N,Travassos da Rosa AP,Guzman H,Detoy K,Popov VL,Walker PJ,Lipkin WI,Vasilakis N,Tesh RB

更新日期：2013-07-01 00:00:00

abstract：:Fatal influenza A virus infection is a major threat to public health throughout the world. Lung macrophages and neutrophils have critical roles for both the pathogenesis and viral clearance of fatal viral infections. These are complicated by the interaction of innate immunity and adaptive immunity against viral infect...

journal_title：Virology journal

authors： Lv J,Hua Y,Wang D,Liu A,An J,Li A,Wang Y,Wang X,Jia N,Jiang Q

更新日期：2014-03-26 00:00:00

abstract：BACKGROUND:Human adenoviruses (Ads) have substantial potential for clinical applications in cancer patients. Conditionally replicating adenoviruses (CRAds) include oncolytic adenoviruses in which expression of the immediate early viral transactivator protein E1A is controlled by a cancer cell-selective promoter. To enh...

journal_title：Virology journal

authors： Fontecedro AC,Lutschg V,Eichhoff O,Dummer R,Greber UF,Hemmi S

更新日期：2010-07-29 00:00:00

abstract：BACKGROUND:The recently sequenced 218 kb genome of morphologically atypical Bacillus thuringiensis phage 0305phi8-36 exhibited only limited detectable homology to known bacteriophages. The only known relative of this phage is a string of phage-like genes called BtI1 in the chromosome of B. thuringiensis israelensis. Th...

journal_title：Virology journal

authors： Hardies SC,Thomas JA,Serwer P

更新日期：2007-10-05 00:00:00

abstract：:The original version of the acknowledgement unfortunately contained a mistake. ...

journal_title：Virology journal

authors： Signer J,Jonsdottir HR,Albrich WC,Strasser M,Züst R,Ryter S,Ackermann-Gäumann R,Lenz N,Siegrist D,Suter A,Schoop R,Engler OB

更新日期：2020-11-09 00:00:00

abstract：BACKGROUND:Hepatitis C Virus (HCV) infected patients are frequently repeatedly exposed to the virus, but very few recombinants between two genotypes have been reported. FINDINGS:We describe the discovery of an HCV recombinant using a method developed in a United States clinical lab for HCV genotyping that employs sequ...

journal_title：Virology journal

authors： Bhattacharya D,Accola MA,Ansari IH,Striker R,Rehrauer WM

更新日期：2011-10-03 00:00:00

abstract：BACKGROUND:To assess the potential effects of telbivudine (LdT) and entecavir (ETV) on renal function in patients with chronic hepatitis B (CHB), we performed a meta-analysis of the relevant data available on these agents to evaluate their effects on the estimated glomerular filtration rate (eGFR) during treatment. ME...

journal_title：Virology journal

authors： Wu X,Cai S,Li Z,Zheng C,Xue X,Zeng J,Peng J

更新日期：2016-04-09 00:00:00

abstract：BACKGROUND:Using a murine model of parainfluenza virus infection (mPIV1 or Sendai virus; SeV), we compared the inflammatory responses to lethal and sub-lethal infections in inbred DBA/2 mice. METHODS:Mice were intranasally inoculated with either 1.6×10(3) or 1.6×10(5) infectious units (IU) of SeV or diluent control. C...

journal_title：Virology journal

authors： Suryadevara M,Bonville CA,Rosenberg HF,Domachowske JB

更新日期：2013-12-21 00:00:00

abstract：:In September 2012, a novel coronavirus was isolated from a patient in Saudi Arabia who had died of an acute respiratory illness and renal failure. The clinical presentation was reminiscent of the outbreak caused by the SARS-coronavirus (SARS-CoV) exactly ten years ago that resulted in over 8000 cases. Sequence analysi...

journal_title：Virology journal

authors： Khan G

更新日期：2013-02-28 00:00:00

abstract：:Members of the genus Cypovirus (family Reoviridae) are common pathogens of insects. These viruses have linear dsRNA genomes divided into 10-11 segments, which have generally been assumed to be monocistronic. Here, bioinformatic evidence is presented for a short overlapping coding sequence (CDS) in the cypovirus genome...

journal_title：Virology journal

authors： Firth AE,Atkins JF

更新日期：2008-05-20 00:00:00

abstract：BACKGROUND:A serological method to simultaneously detect antibodies against infectious laryngotracheitis virus (ILTV) and infectious bronchitis virus (IBV) is imperative for the differential diagnosis and evaluation of antibodies titers after vaccination. METHOD:The microspheres coated with purified recombinant glycop...

journal_title：Virology journal

authors： Wang H,Cong F,Guan J,Xiao L,Zhu Y,Lian Y,Huang R,Chen M,Guo P

更新日期：2018-09-21 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection is a major public health problem with more than 170 million cases of chronic infections worldwide. There is no protective vaccine currently available for HCV, therefore the development of novel strategy to prevent chronic infection is important. We reported earlier that a re...

journal_title：Virology journal

authors： Chandra PK,Hazari S,Poat B,Gunduz F,Prabhu R,Liu G,Burioni R,Clementi M,Garry RF,Dash S

更新日期：2010-06-07 00:00:00

abstract：BACKGROUND:Influenza virus continues to cause significant hospitalization rates in infants and young children. A 2-dose regime of trivalent inactivated vaccine is required to generate protective levels of hemagglutination inhibiting (HAI) antibodies. A vaccine preparation with enhanced immunogenicity is therefore desir...

journal_title：Virology journal

authors： Harris K,Ream R,Gao J,Eichelberger MC

更新日期：2011-05-21 00:00:00

abstract：BACKGROUND:Human papillomaviruses (HPVs), a group of non-enveloped small viruses with double-stranded circular DNA which lead to multiple skin diseases such as benign warts, are commonly seen in clinics. The current HPV detection systems aim mainly at mucosal HPVs, however, an efficient clinical approach for cutaneous ...

journal_title：Virology journal

authors： Wang Y,Ge G,Mao R,Wang Z,Sun YZ,Du YG,Gao XH,Qi RQ,Chen HD

更新日期：2020-07-09 00:00:00

abstract：BACKGROUND:The emergence of influenza viruses resistant to anti-influenza drugs is a threat to global public health. The Korea Centers for Disease Control and Prevention operates the Korea Influenza and Respiratory Viruses Surveillance System (KINRESS) to monitor epidemics of influenza and Severe Acute Respiratory Infe...

journal_title：Virology journal

authors： Kim HM,Lee N,Kim MS,Kang C,Chung YS

更新日期：2020-07-06 00:00:00

abstract：:Lytic bacteriophage 0305phi8-36 forms visually observed aggregates during plaque formation. Aggregates intrinsically lower propagation potential. In the present study, the following observations indicate that lost propagation potential is regained with time: (1) Aggregates sometimes concentrate at the edge of clear pl...

journal_title：Virology journal

authors： Serwer P,Hayes SJ,Lieman K

更新日期：2007-12-04 00:00:00

abstract：BACKGROUND:Infection with hepatitis B virus (HBV) is major public health concern. The limitations of available antiviral drugs require development of novel approaches to inhibit HBV replication. This study was conducted to identify functional elements and new siRNA target sites within the highly conserved regions of th...

journal_title：Virology journal

authors： Panjaworayan N,Payungporn S,Poovorawan Y,Brown CM

更新日期：2010-09-08 00:00:00

abstract：BACKGROUND:Controversy remains as to whether antiviral agents contribute to renal dysfunction in patients with chronic hepatitis B virus (HBV) infection. Thus, the aim of study was to analyze the changes in renal function of chronic hepatitis B (CHB) patients in response to anti-HBV therapy and the association with tre...

journal_title：Virology journal

authors： Zhang Y,Zhang WL,Pang XW,Wang LX,Wei X,Huang CX,Bai XF,Han S,Liu LN,Lian JQ

更新日期：2017-03-09 00:00:00

abstract：BACKGROUND:One requisite of quantitative reverse transcription PCR (qRT-PCR) is to normalise the data with an internal reference gene that is invariant regardless of treatment, such as virus infection. Several studies have found variability in the expression of commonly used housekeeping genes, such as beta-actin (ACTB...

journal_title：Virology journal

authors： Kuchipudi SV,Tellabati M,Nelli RK,White GA,Perez BB,Sebastian S,Slomka MJ,Brookes SM,Brown IH,Dunham SP,Chang KC

更新日期：2012-10-08 00:00:00

abstract：BACKGROUND:In Europe, the north-south downhill cline frequency of the chemokine receptor CCR5 allele with a 32-bp deletion (CCR5-Delta32) raises interesting questions for evolutionary biologists. We had suggested first that, in the past, the European colonizers, principally Romans, might have been instrumental of a pro...

journal_title：Virology journal

authors： Faure E

更新日期：2008-10-16 00:00:00

abstract：:Dengue virus (DENV) is a mosquito-borne virus that has four serotypes. Collection of serum from patients is time- and labor- consuming, and presents a high injury risk for infants and children. The genomic and serological diagnosis of imported dengue fever from a urine sample was used as a non-invasive diagnostic meth...

journal_title：Virology journal

authors： Ma X,Zhen W,Yang P,Sun X,Nie W,Zhang L,Xu H,Hu K

更新日期：2014-03-25 00:00:00

abstract：:Measles, caused by measles virus (MeV), is a common infection in children. MeV is a member of the genus Morbillivirus and is most closely related to rinderpest virus (RPV), which is a pathogen of cattle. MeV is thought to have evolved in an environment where cattle and humans lived in close proximity. Understanding th...

journal_title：Virology journal

authors： Furuse Y,Suzuki A,Oshitani H

更新日期：2010-03-04 00:00:00

abstract：BACKGROUND:Early in infection, the genome of the influenza A virus, consisting of eight complexes of RNA and proteins (termed viral ribonucleoproteins; vRNPs), enters the nucleus of infected cells for replication. Incoming vRNPs are imported into the nucleus of infected cells using at least two nuclear localization seq...

journal_title：Virology journal

authors： Wu WW,Panté N

更新日期：2009-06-02 00:00:00

abstract：BACKGROUND:H6 subtype influenza viruses were prevalent in domestic poultry and wild birds, which also could pose potential threat to humans. However, little is known about the prevalence of H6 subtype viruses in wild birds in eastern China, a crucial stopover or wintering site for migratory wild birds along the East As...

journal_title：Virology journal

authors： Hu C,Li X,Zhu C,Zhou F,Tang W,Wu D,Li Z,Zhou L,Liu J,Wei X,Cui J,Wang T,He G

更新日期：2020-04-29 00:00:00

abstract：BACKGROUND/AIM:Hepatitis C virus (HCV) has been the subject of intense research and clinical investigation as its major role in human disease has emerged. HCV circulates in vivo as a complex population of different but closely related viral variants, commonly referred to as a quasispecies. The extent to which recombina...

journal_title：Virology journal

authors： Moreno MP,Casane D,López L,Cristina J

更新日期：2006-10-24 00:00:00

abstract：BACKGROUND:Polyomaviruses (PyVs) have a wide range of hosts, from humans to fish, and their effects on hosts vary. The differences in the infection characteristics of PyV with respect to the host are assumed to be influenced by the biochemical function of the LT-Ag protein, which is related to the cytopathic effect and...

journal_title：Virology journal

authors： Cho M,Kim H,Son HS

更新日期：2019-11-14 00:00:00