Atypical depression spectrum disorder - neurobiology and treatment.

abstract：OBJECTIVE:To investigate gender differences in psychiatric comorbidity patients diagnosed with attention-deficit hyperactivity disorder (ADHD) as adults. METHODS:Interviews about current ADHD symptoms and psychiatric comorbidity on axis I and II (Structured Clinical Interview for DSM-IV axis I and axis II) were conduc...

journal_title：Acta neuropsychiatrica

authors： Edvinsson D,Lindström E,Bingefors K,Lewander T,Ekselius L

更新日期：2013-06-01 00:00:00

abstract：:Depression is a frequent comorbid disorder of many inflammatory diseases and it is suggested that brain inflammatory processes have a pathogenic role in mood dysregulation. Several immunocompromised patients have been treated with cytokines and long-term treatments have resulted in a variety of neuropsychiatric side-e...

journal_title：Acta neuropsychiatrica

authors： Fekkes D,Van Gool AR

更新日期：2003-02-01 00:00:00

abstract：:In the past decade, neuroimaging research has identified key components in the neural system that underlies bipolar disorder (BD). The ventral prefrontal cortex (VPFC) and amygdala are highly interconnected structures that jointly play a central role in emotional regulation. Numerous research groups have reported prom...

journal_title：Acta neuropsychiatrica

authors： Womer FY,Kalmar JH,Wang F,Blumberg HP

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:ConstaTRE is an open-label, randomised, controlled, relapse prevention trial in patients with stable schizophrenia or schizoaffective disorder switched to risperidone long-acting injectable (RLAI) or oral quetiapine, and was designed to test the hypothesis that injectable antipsychotic treatment with risperid...

journal_title：Acta neuropsychiatrica

authors： Rouillon F,Eriksson L,Burba B,Raboch J,Kaprinis G,Schreiner A

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:The FATIMA study (FAst TItration of quetiapine fumarate in bipolar I MAnia) evaluated the safety, tolerability and efficacy of a rapid dose escalation of quetiapine in acutely ill bipolar I patients experiencing a manic episode. METHODS:In an open-label, phase II pilot study, 29 patients aged 18 years or old...

journal_title：Acta neuropsychiatrica

authors： Constant E,Seghers A,Ranalli E,Ryckmans V,Snauwaert P,Parent M,Vandenhoven G

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:This study used a prospective design and the technique of structural modelling to examine the complex interrelations between psychological factors, immune status and complications after major surgery. METHODS:Twenty-nine women scheduled for elective cholecystectomy were studied prospectively. Information reg...

journal_title：Acta neuropsychiatrica

authors： Vollmer-Conna U,Bird KD,Yeo BW,Truskett PG,Westbrook RF,Wakefield D

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:The mechanisms involved in the dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, especially in the functioning of glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) in depressed patients, are not well elucidated. The objective of this study was to conduct a systematic review of art...

journal_title：Acta neuropsychiatrica

authors： Von Werne Baes C,de Carvalho Tofoli SM,Martins CM,Juruena MF

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to analyse demographic and clinical characteristics, as well as psychiatric diagnoses to identify gender differences in patients with attempted suicide in a Mexican population. METHODS:Between September 2010 and September 2012, 140 suicide attempts were documented in the Depa...

journal_title：Acta neuropsychiatrica

authors： Fresán A,González-Castro TB,Peralta-Jiménez Y,Juárez-Rojop I,Pool-García S,Velázquez-Sánchez MP,López-Narváez L,Tovilla-Zárate CA

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Previous studies suggest that brain serotonin neurotransmission may mediate the actions of lithium carbonate. Acute tryptophan depletion (ATD) reduces brain serotonin and allows the study of this neurotransmitter in patient groups. Serotonin modulates electroencephalographic (EEG) activity, which is abnormal...

journal_title：Acta neuropsychiatrica

authors： Young AH,Hughes JH,Ashton CH

更新日期：2000-09-01 00:00:00

abstract：:For more than 20 years, patients with borderline personality disorder have been treated as in-patients in the UC St-Jozef in Kortenberg, Belgium. The majority of these patients were treated in a psychoanalytical or a behavior therapy ward. During these years, the treatment programs of these wards were gradually adjust...

journal_title：Acta neuropsychiatrica

authors： Pieters G,Vermote R

更新日期：2002-04-01 00:00:00

abstract：:Neuroleptic malignant syndrome (NMS) is associated with the administration of antipsychotic agents and other drugs such as l-dopa, antidepressants, and antihistaminic agents. Unexpected changes in mental status, new-onset catatonia, episodic tachycardia, tachypnea, hypertension, dysarthria, dysphagia, diaphoresis, sia...

journal_title：Acta neuropsychiatrica

authors： Ananth J,Aduri K,Parameswaran S,Gunatilake S

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the involvement of nod-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome in schizophrenia-like behaviour in young animals exposed to maternal immune activation (MIA). METHODS:To this aim, on the 15th gestational day, the females received an injection of lipopolysaccharides. Whe...

journal_title：Acta neuropsychiatrica

authors： Ventura L,Freiberger V,Thiesen VB,Dias P,Dutra ML,Silva BB,Schlindwein AD,Comim CM

更新日期：2020-12-01 00:00:00

abstract：:There has been growing interest in the role of serotonin (5-hydroxytryptamine, 5-HT) in anxiety, including pathological states such as panic disorder. The technique of tryptophan depletion (TD), which causes an acute, temporary and reversible reduction in brain 5-HT levels, is a useful minimally invasive paradigm to a...

journal_title：Acta neuropsychiatrica

authors： Pyle AC,Argyropoulos SV,Nutt DJ

更新日期：2004-04-01 00:00:00

abstract：:A huge number of natural and synthetic compounds modulate the function of the γ-aminobutyric acid type A receptor (GABAA-R) by interacting with several allosteric binding sites which may differ in the various GABAA-R subtypes. The benzodiazepine receptor (BDZ-R) is the most intensively studied allosteric site. It is t...

journal_title：Acta neuropsychiatrica

authors： Vermeulen PJ,Zitman FG

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE:Typical and atypical antipsychotic drugs have been shown to have different clinical, biochemical and behavioural profiles. It is well described that impairment of metabolism, especially in the mitochondria, leads to oxidative stress and neuronal death and has been implicated in the pathogenesis of a number of...

journal_title：Acta neuropsychiatrica

authors： Scaini G,Rochi N,Morais MO,Maggi DD,De-Nês BT,Quevedo J,Streck EL

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Physical hyperactivity has often been described in anorexia nervosa (AN) patients but up until now in-depth research has been scarce. Experience sampling methodology (ESM), a structured diary technique assessing momentary mental state at random times during the day, may be useful in studying hyperactivity in...

journal_title：Acta neuropsychiatrica

authors： Pieters G,Vansteelandt K,Claes L,Probst M,Van Mechelen I,Vandereycken W

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:Psychometric research in the field of alcohol dependence has concentrated on identifying certain (personality) characteristics (i.e. typologies). This paper is aimed to identify such typologies and studies the relation of the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) and Cloninger's temperament-c...

journal_title：Acta neuropsychiatrica

authors： Egger JI,Gringhuis M,Breteler MA,De Mey HR,Wingbermühle E,Derksen JJ,Hilberink S

更新日期：2007-08-01 00:00:00

abstract：:In the past decade, neuroimaging research has identified key components in the neural system that underlies bipolar disorder (BD). The ventral prefrontal cortex (VPFC) and amygdala are highly interconnected structures that jointly play a central role in emotional regulation. Numerous research groups have reported prom...

journal_title：Acta neuropsychiatrica

authors： Womer FY,Kalmar JH,Wang F,Blumberg HP

更新日期：2009-09-23 00:00:00

abstract：BACKGROUND:Female patients with anorexia nervosa differ significantly from the control women in various dimensions of personality. OBJECTIVE:To investigate the personality dimensions measured with the Temperament and Character Inventory (TCI) in adolescent patients with restrictive-type and bulimic/purging-type anorex...

journal_title：Acta neuropsychiatrica

authors： Rybakowski F,Slopien A,Zakrzewska M,Hornowska E,Rajewski A

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:Recent observations demonstrate a significant ameliorative effect of add-on transcranial direct current stimulation (tDCS) on auditory verbal hallucinations (AVHs) in schizophrenia. Of the many SNPs, NRG1 rs35753505 and catechol-o-methyl transferase (COMT) rs4680 polymorphisms have shown to have a strong asso...

journal_title：Acta neuropsychiatrica

authors： Chhabra H,Shivakumar V,Subbanna M,Kalmady SV,Bose A,Agarwal SM,Sreeraj VS,Dinakaran D,Narayanaswamy JC,Debnath M,Venkatasubramanian G

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Double depression, the combination of major depression and dysthymia, is associated with poor health-related quality of life (HRQoL) and increased health service utilization. OBJECTIVE:To determine the prevalence of double depression, its associated morbidity and use of health services and antidepressants. ...

journal_title：Acta neuropsychiatrica

authors： Goldney RD,Bain MA

更新日期：2006-10-01 00:00:00

abstract：:The elucidation of sleep regulation is not an easy task. On one side, there is a multitude of solid yet disparate data, on the other side, the topic is tempting for engaging in wild speculation, particularly with respect to the functions of sleep. Models may exert a moderating influence by mediating between the two ex...

journal_title：Acta neuropsychiatrica

authors： Borbély AA

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:Fas (CD95), commonly categorised as a death receptor due to its well-defined role in apoptosis, can paradoxically also promote neuroprotection. We have previously found that defects in Fas signalling render mice highly susceptible to neural degeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mous...

journal_title：Acta neuropsychiatrica

authors： Landau AM,Siegrist-Johnstone R,Desbarats J

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To develop and test a novel fMRI compatible comprehensive and expressive language task that reliably and predictably activates both Wernicke's and Broca's cortical brain regions, respectively, and has utility for the determination of hemispheric language dominance. METHODS:Ten healthy men (seven) and women (...

journal_title：Acta neuropsychiatrica

authors： Berntsen EM,Rasmussen IA,Samuelsen P,Xu J,Haraldseth O,Lagopoulos J,Malhi GS

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:Long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) are in increasing use in the general population to treat health problems. The objective of the current article is to review the evidence for the rationale and benefit of LCn-3PUFA in the treatment of common psychiatric disorders in children and adoles...

journal_title：Acta neuropsychiatrica

authors： Clayton EH,Hanstock TL,Garg ML,Hazell PL

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of and factors associated with depression and stress with perceived quality of life and the salivary cortisol levels in Community Health Agent (CHA). Materials and Methods Cross-sectional descriptive study of CHAs in Pelotas-RS, Brazil. Data collection, including sociodemographic i...

journal_title：Acta neuropsychiatrica

authors： Knuth BS,Cocco RA,Radtke VA,Medeiros JR,Oses JP,Wiener CD,Jansen K

更新日期：2016-06-01 00:00:00

abstract：:Since the description of SAD the prevalence of this disorder has been of particular interest. The more so, because early studies, indicated the correctness of the on theoretical grounds - expected interaction between latitude and prevalence rate of SAD. More eleborate prevalence studies, mainly in the USA indeed showe...

journal_title：Acta neuropsychiatrica

authors： Mersch PP,Middendorp H,Bouhuys AL,Beersma DG,van den Hoofdakker RH

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:The aim of the current study was to examine whether and to what extent mood disorders, comprising major depression and bipolar disorder, are accompanied by structural changes in the brain as measured using voxel-based morphometry (VBM). METHODS:We performed a VBM study using a 3Т MRI system (GE Discovery 750...

journal_title：Acta neuropsychiatrica

authors： Kandilarova S,Stoyanov D,Sirakov N,Maes M,Specht K

更新日期：2019-10-01 00:00:00

abstract：:The alterations in the inflammatory response system (IRS) appear to be quite different between OCD and anorexia nervosa and are also different from the changes observed in major depression. In anorexia nervosa, there is some evidence for increased production of monocytic cytokines, i.e. tumor necrosis factor-α (TNFα) ...

journal_title：Acta neuropsychiatrica

authors： van West D,Maes M

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:Stress can stimulate increased production of oxygen radicals. We investigated the correlations between serum levels of lipid peroxidation markers and those in brain samples in different stress models. METHODS:Animals (n = 96) were divided equally into eight groups: a control group and groups treated with vit...

journal_title：Acta neuropsychiatrica

authors： Celikbilek A,Gocmen AY,Tanik N,Yaras N,Yargicoglu P,Gumuslu S

更新日期：2014-02-01 00:00:00