Safety, tolerability and efficacy of a rapid dose escalation of quetiapine in bipolar I mania: the FATIMA study.

abstract：OBJECTIVE:Recent observations demonstrate a significant ameliorative effect of add-on transcranial direct current stimulation (tDCS) on auditory verbal hallucinations (AVHs) in schizophrenia. Of the many SNPs, NRG1 rs35753505 and catechol-o-methyl transferase (COMT) rs4680 polymorphisms have shown to have a strong asso...

journal_title：Acta neuropsychiatrica

authors： Chhabra H,Shivakumar V,Subbanna M,Kalmady SV,Bose A,Agarwal SM,Sreeraj VS,Dinakaran D,Narayanaswamy JC,Debnath M,Venkatasubramanian G

更新日期：2018-08-01 00:00:00

abstract：:A psychofysiological study of the cardiac adaptivity to attention-demanding reaction time tasks demonstrated that children with a lesser variant of the pervasive developmental disorder (DSM-IV: PDDNOS) exhibit less cardiac responsiveness to attention tasks than healthy children do. We studied changes in heart rate var...

journal_title：Acta neuropsychiatrica

authors： Althaus M,Aarnoudse CC,Mulder LJ,Mulder G,Minderaa RB

更新日期：1999-09-01 00:00:00

abstract：:For more than 20 years, patients with borderline personality disorder have been treated as in-patients in the UC St-Jozef in Kortenberg, Belgium. The majority of these patients were treated in a psychoanalytical or a behavior therapy ward. During these years, the treatment programs of these wards were gradually adjust...

journal_title：Acta neuropsychiatrica

authors： Pieters G,Vermote R

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:The mechanisms involved in the dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, especially in the functioning of glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) in depressed patients, are not well elucidated. The objective of this study was to conduct a systematic review of art...

journal_title：Acta neuropsychiatrica

authors： Von Werne Baes C,de Carvalho Tofoli SM,Martins CM,Juruena MF

更新日期：2012-02-01 00:00:00

abstract：:Biological schizophrenia research has been dominated by the dopamine hypothesis for decades, but in recent years a more diversified view has gained increasing attention. Several neurotransmitters are now being discussed, and especially their interaction in complex circuitries. The demonstration of an atypical profile ...

journal_title：Acta neuropsychiatrica

authors： Carlsson A

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Studies on the determinants of the quality of life (QOL) after stroke bring differing results depending on the applied concept of QOL. This may lead to confusion about the contribution of various factors to the post-stroke QOL. OBJECTIVE:The aim of the study was: (i) to investigate functional and psychologi...

journal_title：Acta neuropsychiatrica

authors： Jaracz K,Jaracz J,Kozubski W,Rybakowski JK

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVES:Disturbances in the noradrenergic system, including alterations in the densities of α2-adrenoceptors, are posited to be involved in the pathophysiology of depression. In this study, we investigate the binding of α2-adrenoceptors in regions relevant to depression in an animal model of depression. METHODS:Usi...

journal_title：Acta neuropsychiatrica

authors： Lillethorup TP,Iversen P,Wegener G,Doudet DJ,Landau AM

更新日期：2015-12-01 00:00:00

abstract：:Over the past 25 years much effort has been put into the research of the relationship between neuropsychiatric disorders and the concentrations of CSF-monoamine metabolites. Most of this research has beenfocused on the relation between CSF-concentrations of 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HV...

journal_title：Acta neuropsychiatrica

authors： Verhoeven WM

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVE:Fas (CD95), commonly categorised as a death receptor due to its well-defined role in apoptosis, can paradoxically also promote neuroprotection. We have previously found that defects in Fas signalling render mice highly susceptible to neural degeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mous...

journal_title：Acta neuropsychiatrica

authors： Landau AM,Siegrist-Johnstone R,Desbarats J

更新日期：2012-06-01 00:00:00

abstract：:Melatonin is a hormone secreted by the pineal gland mainly during the night. The discovery that this melatonin secretion decreases under the influence of bright light, gave rise to the use of light therapy in some affective disorders. The literature on the relationship between melatonin secretion and mood is reviewed ...

journal_title：Acta neuropsychiatrica

authors： Beullens J

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Recognition memory dysfunction has been frequently reported in schizophrenic populations, and has been linked with the development of delusions and thought disorder. A range of neuropsychological abnormalities have also been documented in the biological asymptomatic relatives of patients with schizophrenia; ...

journal_title：Acta neuropsychiatrica

authors： Edelstyn NM,Drakeford J,Oyebode F,Findlay CD

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:The differentiation between a 'non-organic' depressive episode and an organic depressive disorder on the basis of clinical grounds might be challenging. METHODS:We report a case with an initially typical severe depressive episode without any focal neurological deficits. RESULTS:Only medical history from a t...

journal_title：Acta neuropsychiatrica

authors： Etgen T,Fleissner S

更新日期：2013-08-01 00:00:00

abstract：:Depression is a frequent comorbid disorder of many inflammatory diseases and it is suggested that brain inflammatory processes have a pathogenic role in mood dysregulation. Several immunocompromised patients have been treated with cytokines and long-term treatments have resulted in a variety of neuropsychiatric side-e...

journal_title：Acta neuropsychiatrica

authors： Fekkes D,Van Gool AR

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Somatization has been defined in a number of ways. Despite their differences, these definitions have one element in common, namely the presence of somatic symptoms that cannot be explained (adequately) by organic findings. OBJECTIVE:The primary objectives of the dissertation were to gain a better insight in...

journal_title：Acta neuropsychiatrica

authors： De Gucht V

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To review the literature comparing electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS) for major depression. METHODS:Data from the six randomised, prospective studies were agglutinated into one data set. Special attention was given to the methods of both TMS and ECT as well as data pe...

journal_title：Acta neuropsychiatrica

authors： Rasmussen KG

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:We investigated whether the nitric oxide (NO) precursor, L-arginine, can prevent the antidepressant-like action of the fast-acting antidepressant, ketamine, in a genetic rat model of depression, and/or induce changes in the glutamate (Glu)/N-methyl-D-aspartate receptor (NMDAR)/NO/cyclic guanosine monophosphat...

journal_title：Acta neuropsychiatrica

authors： Liebenberg N,Joca S,Wegener G

更新日期：2015-04-01 00:00:00

abstract：:A huge number of natural and synthetic compounds modulate the function of the γ-aminobutyric acid type A receptor (GABAA-R) by interacting with several allosteric binding sites which may differ in the various GABAA-R subtypes. The benzodiazepine receptor (BDZ-R) is the most intensively studied allosteric site. It is t...

journal_title：Acta neuropsychiatrica

authors： Vermeulen PJ,Zitman FG

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Female patients with anorexia nervosa differ significantly from the control women in various dimensions of personality. OBJECTIVE:To investigate the personality dimensions measured with the Temperament and Character Inventory (TCI) in adolescent patients with restrictive-type and bulimic/purging-type anorex...

journal_title：Acta neuropsychiatrica

authors： Rybakowski F,Slopien A,Zakrzewska M,Hornowska E,Rajewski A

更新日期：2004-06-01 00:00:00

abstract：:In the past decade, neuroimaging research has identified key components in the neural system that underlies bipolar disorder (BD). The ventral prefrontal cortex (VPFC) and amygdala are highly interconnected structures that jointly play a central role in emotional regulation. Numerous research groups have reported prom...

journal_title：Acta neuropsychiatrica

authors： Womer FY,Kalmar JH,Wang F,Blumberg HP

更新日期：2009-09-23 00:00:00

abstract：BACKGROUND:Schizophrenia is consistently associated with lower IQ compared to the IQ of control groups, or estimated premorbid IQ. It is not likely that the IQ scores deteriorate during the prodromal phase or first psychotic episode; they are already present before the onset of the prodromal phase and have been detecte...

journal_title：Acta neuropsychiatrica

authors： van Beilen M,Withaar F,van Zomeren AH,van den Bosch R

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:Long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) are in increasing use in the general population to treat health problems. The objective of the current article is to review the evidence for the rationale and benefit of LCn-3PUFA in the treatment of common psychiatric disorders in children and adoles...

journal_title：Acta neuropsychiatrica

authors： Clayton EH,Hanstock TL,Garg ML,Hazell PL

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of transcranially applied pulsed electromagnetic fields (PEMF) on functional impairments and symptom severity in multiple chemical sensitivity (MCS) patients. METHODS:The study was conducted as a nationwide trial in Denmark using a randomised, parallel-group, double-blind and placebo...

journal_title：Acta neuropsychiatrica

authors： Tran MTD,Skovbjerg S,Arendt-Nielsen L,Christensen KB,Elberling J

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Bacterial meningitis is an infection of the central nervous system characterised by strong inflammatory response. The brain is highly dependent on ATP, and the cell energy is obtained through oxidative phosphorylation, a process which requires the action of various respiratory enzyme complexes and creatine k...

journal_title：Acta neuropsychiatrica

authors： Barichello T,Simões LR,Generoso JS,Carradore MM,Moreira AP,Panatto AP,Costa CS,Filho AS,Jeremias IC,Bez GD,Streck E

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:ConstaTRE is an open-label, randomised, controlled, relapse prevention trial in patients with stable schizophrenia or schizoaffective disorder switched to risperidone long-acting injectable (RLAI) or oral quetiapine, and was designed to test the hypothesis that injectable antipsychotic treatment with risperid...

journal_title：Acta neuropsychiatrica

authors： Rouillon F,Eriksson L,Burba B,Raboch J,Kaprinis G,Schreiner A

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Encephalitis due to anti-N-methyl-D-aspartate receptor antibodies (ANMDARE) is the most frequent immune-mediated encephalitis. It is distinguished by the subacute onset of neuropsychiatric symptoms. OBJECTIVE:To evaluate the characteristic neuropsychiatric symptoms and their outcome in patients diagnosed wi...

journal_title：Acta neuropsychiatrica

authors： Restrepo-Martinez M,Ramirez-Bermudez J,Bayliss L,Espinola-Nadurille M

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:To investigate oxidative stress parameters [total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), paraoxonase (PON), arylesterase (ARE) and thiol-disulphide homeostasis] in patients who were diagnosed as having somatic symptom disorder in accordance with Diagnostic and Stat...

journal_title：Acta neuropsychiatrica

authors： Kabadayi Sahin E,Caykoylu A,Senat A,Erel O

更新日期：2018-12-18 00:00:00

abstract：OBJECTIVE:Typical and atypical antipsychotic drugs have been shown to have different clinical, biochemical and behavioural profiles. It is well described that impairment of metabolism, especially in the mitochondria, leads to oxidative stress and neuronal death and has been implicated in the pathogenesis of a number of...

journal_title：Acta neuropsychiatrica

authors： Scaini G,Rochi N,Morais MO,Maggi DD,De-Nês BT,Quevedo J,Streck EL

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To investigate gender differences in psychiatric comorbidity patients diagnosed with attention-deficit hyperactivity disorder (ADHD) as adults. METHODS:Interviews about current ADHD symptoms and psychiatric comorbidity on axis I and II (Structured Clinical Interview for DSM-IV axis I and axis II) were conduc...

journal_title：Acta neuropsychiatrica

authors： Edvinsson D,Lindström E,Bingefors K,Lewander T,Ekselius L

更新日期：2013-06-01 00:00:00

abstract：:Most forms of behaviour whether normal or abnormal, show a tendency to run in families. However, these can range from symptoms of dementia and movement disorder caused by the comparatively rare autosomal dominant Huntington's disease to common everyday aspects of behaviour such as religious persuasion or career choice...

journal_title：Acta neuropsychiatrica

authors： McGuffin P

更新日期：1999-06-01 00:00:00

abstract：:In the past decade, neuroimaging research has identified key components in the neural system that underlies bipolar disorder (BD). The ventral prefrontal cortex (VPFC) and amygdala are highly interconnected structures that jointly play a central role in emotional regulation. Numerous research groups have reported prom...

journal_title：Acta neuropsychiatrica

authors： Womer FY,Kalmar JH,Wang F,Blumberg HP

更新日期：2009-10-01 00:00:00