Abstract:
BACKGROUND:Somatization has been defined in a number of ways. Despite their differences, these definitions have one element in common, namely the presence of somatic symptoms that cannot be explained (adequately) by organic findings. OBJECTIVE:The primary objectives of the dissertation were to gain a better insight into the concept of somatization, and to study (prospectively) the relationship between neuroticism and alexithymia, two personality traits that have been shown to be related to somatization, the affective state dimensions positive and negative affect (or psychological distress) and medically unexplained symptoms. METHOD:A selective review was conducted regarding conceptual and methodological issues related to somatization. A total number of 318 patients, presenting to their primary care physician with medically unexplained symptoms, participated in the prospective study. Both at baseline and at 6-month follow-up a number of measures were filled out with respect to somatization, neuroticism, alexithymia, negative and positive affect, anxiety and depression. RESULTS:The concept of somatization was clarified, thereby making use of the distinction between presenting and functional somatization. The personality traits neuroticism and alexithymia were found to have an indirect influence on symptom reports. Both the cross-sectional and follow-up data pointed to the importance of positive and negative affect as determinants of (changes in) number of symptoms (over time). Negative affect, together with the alexithymia dimension measuring difficulty identifying feelings, predicted symptom persistence. CONCLUSIONS:The theoretical as well as therapeutic implications of the present paper may give an impetus to new research in the domain of somatization.
journal_name
Acta Neuropsychiatrjournal_title
Acta neuropsychiatricaauthors
De Gucht Vdoi
10.1034/j.1601-5215.2002.140404.xsubject
Has Abstractpub_date
2002-08-01 00:00:00pages
181-5issue
4eissn
0924-2708issn
1601-5215pii
S0924270800005044journal_volume
14pub_type
杂志文章abstract:OBJECTIVE:To determine the prevalence of and factors associated with depression and stress with perceived quality of life and the salivary cortisol levels in Community Health Agent (CHA). Materials and Methods Cross-sectional descriptive study of CHAs in Pelotas-RS, Brazil. Data collection, including sociodemographic i...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2015.58
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:The aims of this study were to determine the dominant affective temperament changes in stroke survivors and whether temperament affects the disability. METHODS:A total of 63 stroke patients were included in this study. Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire was used to...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2008.00335.x
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Female patients with anorexia nervosa differ significantly from the control women in various dimensions of personality. OBJECTIVE:To investigate the personality dimensions measured with the Temperament and Character Inventory (TCI) in adolescent patients with restrictive-type and bulimic/purging-type anorex...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.0924-2708.2004.00073.x
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abstract:OBJECTIVE:Prisoners categorised as 'dangerous' are a category of prisoners that require and/or force into using special measures of caution, protection and security. The aim of the study was to examine the intensity of anxiety (as a state and as a trait) experienced by officers working with 'dangerous' prisoners and st...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2015.31
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Despite various studies, supportive evidence for the efficacy of exercise in treatment of mental illness is still weak. OBJECTIVE:The aim of this study was to compare two forms of exercise, namely running therapy (RT) and physiotraining therapy (PT), on stationary devices. METHODS:Patients in a day treatme...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2006.00115.x
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to report the frequency of autoimmune disorders and autoantibodies in 22 patients with neuromyelitis optica (NMO), as well as whether the seropositivity for autoantibodies differs between anti-aquaporin 4 (AQP4) positive and AQP4 negative NMO patients. METHODS:Demographic, medical r...
journal_title:Acta neuropsychiatrica
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doi:10.1017/neu.2016.49
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:The FATIMA study (FAst TItration of quetiapine fumarate in bipolar I MAnia) evaluated the safety, tolerability and efficacy of a rapid dose escalation of quetiapine in acutely ill bipolar I patients experiencing a manic episode. METHODS:In an open-label, phase II pilot study, 29 patients aged 18 years or old...
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pub_type: 杂志文章
doi:10.1111/j.1601-5215.2009.00378.x
更新日期:2009-06-01 00:00:00
abstract::For more than 20 years, patients with borderline personality disorder have been treated as in-patients in the UC St-Jozef in Kortenberg, Belgium. The majority of these patients were treated in a psychoanalytical or a behavior therapy ward. During these years, the treatment programs of these wards were gradually adjust...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1034/j.1601-5215.2002.140206.x
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:Encephalitis due to anti-N-methyl-D-aspartate receptor antibodies (ANMDARE) is the most frequent immune-mediated encephalitis. It is distinguished by the subacute onset of neuropsychiatric symptoms. OBJECTIVE:To evaluate the characteristic neuropsychiatric symptoms and their outcome in patients diagnosed wi...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2019.46
更新日期:2020-04-01 00:00:00
abstract::Depression is a frequent comorbid disorder of many inflammatory diseases and it is suggested that brain inflammatory processes have a pathogenic role in mood dysregulation. Several immunocompromised patients have been treated with cytokines and long-term treatments have resulted in a variety of neuropsychiatric side-e...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1034/j.1601-5215.2003.00007.x
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVE:The aim of the current study was to examine whether and to what extent mood disorders, comprising major depression and bipolar disorder, are accompanied by structural changes in the brain as measured using voxel-based morphometry (VBM). METHODS:We performed a VBM study using a 3Т MRI system (GE Discovery 750...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2019.20
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:The incidence of restless legs syndrome (RLS) is presumed to be higher among people with schizophrenia who take antipsychotic medication, most of which blocks the dopamine D2 receptor. The purpose of this study was to determine whether the G-protein β3 subunit (GNB3) C825T polymorphism is associated with anti...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2007.00240.x
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the involvement of nod-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome in schizophrenia-like behaviour in young animals exposed to maternal immune activation (MIA). METHODS:To this aim, on the 15th gestational day, the females received an injection of lipopolysaccharides. Whe...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2020.27
更新日期:2020-12-01 00:00:00
abstract::Melatonin is a hormone secreted by the pineal gland mainly during the night. The discovery that this melatonin secretion decreases under the influence of bright light, gave rise to the use of light therapy in some affective disorders. The literature on the relationship between melatonin secretion and mood is reviewed ...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/S0924270800037376
更新日期:1995-09-01 00:00:00
abstract:OBJECTIVE:The differentiation between a 'non-organic' depressive episode and an organic depressive disorder on the basis of clinical grounds might be challenging. METHODS:We report a case with an initially typical severe depressive episode without any focal neurological deficits. RESULTS:Only medical history from a t...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2013.19
更新日期:2013-08-01 00:00:00
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journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2011.00610.x
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:Recent observations demonstrate a significant ameliorative effect of add-on transcranial direct current stimulation (tDCS) on auditory verbal hallucinations (AVHs) in schizophrenia. Of the many SNPs, NRG1 rs35753505 and catechol-o-methyl transferase (COMT) rs4680 polymorphisms have shown to have a strong asso...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
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更新日期:2018-08-01 00:00:00
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journal_title:Acta neuropsychiatrica
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doi:10.1017/neu.2014.21
更新日期:2014-12-01 00:00:00
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journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2007.00167.x
更新日期:2007-02-01 00:00:00
abstract::Objective This study explored the utility of the Health Belief Models (HBM) in explaining medication adherence in subjects with severe affective disorders. Method Well established measuring instruments, with confirmed reliability and validity, were used to assess each component of two HBMs and adherence with mood stab...
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pub_type: 杂志文章
doi:10.1017/S0924270800035584
更新日期:2000-09-01 00:00:00
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journal_title:Acta neuropsychiatrica
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更新日期:2014-06-01 00:00:00
abstract::Immunopathogenesis of multiple sclerosis is a complex process involving T cell mediated autoimmunity at initial stage of disease. A long standing view that Th1 cells are critical for early inflammatory development of lesions is challenging by recent findings that Th1 helper cells with Th17 phenotype are even more impo...
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pub_type: 杂志文章
doi:10.1017/S0924270800032622
更新日期:2009-06-01 00:00:00
abstract::In the past decade, neuroimaging research has identified key components in the neural system that underlies bipolar disorder (BD). The ventral prefrontal cortex (VPFC) and amygdala are highly interconnected structures that jointly play a central role in emotional regulation. Numerous research groups have reported prom...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2009.00414.x
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:Ginsenosides, biologically-active components of the root of Panax ginseng, have been reported to have therapeutic benefits in a number of disease states including psychiatric conditions such as major depressive disorder. Our objective was to determine if a standardized commercial ginseng extract, G115®, could...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2021.2
更新日期:2021-01-22 00:00:00
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journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1034/j.1601-5215.2003.00044.x
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:Long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) are in increasing use in the general population to treat health problems. The objective of the current article is to review the evidence for the rationale and benefit of LCn-3PUFA in the treatment of common psychiatric disorders in children and adoles...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2007.00189.x
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:ConstaTRE is an open-label, randomised, controlled, relapse prevention trial in patients with stable schizophrenia or schizoaffective disorder switched to risperidone long-acting injectable (RLAI) or oral quetiapine, and was designed to test the hypothesis that injectable antipsychotic treatment with risperid...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2013.7
更新日期:2013-10-01 00:00:00
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journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2020.36
更新日期:2020-10-15 00:00:00
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journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/S092427080003605X
更新日期:1999-09-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to analyse demographic and clinical characteristics, as well as psychiatric diagnoses to identify gender differences in patients with attempted suicide in a Mexican population. METHODS:Between September 2010 and September 2012, 140 suicide attempts were documented in the Depa...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2015.6
更新日期:2015-06-01 00:00:00