Neuroticism, alexithymia, negative affect and positive affect as predictors of medically unexplained symptoms in primary care.

Abstract:

BACKGROUND:Somatization has been defined in a number of ways. Despite their differences, these definitions have one element in common, namely the presence of somatic symptoms that cannot be explained (adequately) by organic findings. OBJECTIVE:The primary objectives of the dissertation were to gain a better insight into the concept of somatization, and to study (prospectively) the relationship between neuroticism and alexithymia, two personality traits that have been shown to be related to somatization, the affective state dimensions positive and negative affect (or psychological distress) and medically unexplained symptoms. METHOD:A selective review was conducted regarding conceptual and methodological issues related to somatization. A total number of 318 patients, presenting to their primary care physician with medically unexplained symptoms, participated in the prospective study. Both at baseline and at 6-month follow-up a number of measures were filled out with respect to somatization, neuroticism, alexithymia, negative and positive affect, anxiety and depression. RESULTS:The concept of somatization was clarified, thereby making use of the distinction between presenting and functional somatization. The personality traits neuroticism and alexithymia were found to have an indirect influence on symptom reports. Both the cross-sectional and follow-up data pointed to the importance of positive and negative affect as determinants of (changes in) number of symptoms (over time). Negative affect, together with the alexithymia dimension measuring difficulty identifying feelings, predicted symptom persistence. CONCLUSIONS:The theoretical as well as therapeutic implications of the present paper may give an impetus to new research in the domain of somatization.

journal_name

Acta Neuropsychiatr

journal_title

Acta neuropsychiatrica

authors

De Gucht V

doi

10.1034/j.1601-5215.2002.140404.x

subject

Has Abstract

pub_date

2002-08-01 00:00:00

pages

181-5

issue

4

eissn

0924-2708

issn

1601-5215

pii

S0924270800005044

journal_volume

14

pub_type

杂志文章
  • Stress, depression, quality of life and salivary cortisol levels in community health agents.

    abstract:OBJECTIVE:To determine the prevalence of and factors associated with depression and stress with perceived quality of life and the salivary cortisol levels in Community Health Agent (CHA). Materials and Methods Cross-sectional descriptive study of CHAs in Pelotas-RS, Brazil. Data collection, including sociodemographic i...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2015.58

    authors: Knuth BS,Cocco RA,Radtke VA,Medeiros JR,Oses JP,Wiener CD,Jansen K

    更新日期:2016-06-01 00:00:00

  • Affective temperament in stroke patients.

    abstract:OBJECTIVE:The aims of this study were to determine the dominant affective temperament changes in stroke survivors and whether temperament affects the disability. METHODS:A total of 63 stroke patients were included in this study. Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire was used to...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2008.00335.x

    authors: Kurt E,Karacan I,Ozaras N,Alatas G

    更新日期:2008-12-01 00:00:00

  • Temperament and Character Inventory (TCI) in adolescents with anorexia nervosa.

    abstract:BACKGROUND:Female patients with anorexia nervosa differ significantly from the control women in various dimensions of personality. OBJECTIVE:To investigate the personality dimensions measured with the Temperament and Character Inventory (TCI) in adolescent patients with restrictive-type and bulimic/purging-type anorex...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.0924-2708.2004.00073.x

    authors: Rybakowski F,Slopien A,Zakrzewska M,Hornowska E,Rajewski A

    更新日期:2004-06-01 00:00:00

  • Anxiety and styles of coping with occupational stress resulting from work with 'dangerous' prisoners in prison service officers.

    abstract:OBJECTIVE:Prisoners categorised as 'dangerous' are a category of prisoners that require and/or force into using special measures of caution, protection and security. The aim of the study was to examine the intensity of anxiety (as a state and as a trait) experienced by officers working with 'dangerous' prisoners and st...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2015.31

    authors: Tsirigotis K,Gruszczyński W,Pęczkowski S

    更新日期:2015-10-01 00:00:00

  • Comparing running therapy with physiotraining therapy in the treatment of mood disorders.

    abstract:BACKGROUND:Despite various studies, supportive evidence for the efficacy of exercise in treatment of mental illness is still weak. OBJECTIVE:The aim of this study was to compare two forms of exercise, namely running therapy (RT) and physiotraining therapy (PT), on stationary devices. METHODS:Patients in a day treatme...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2006.00115.x

    authors: Judith Haffmans PM,Kleinsman AC,van Weelden C,Huijbrechts IP,Hoencamp E

    更新日期:2006-06-01 00:00:00

  • Frequency of autoimmune disorders and autoantibodies in patients with neuromyelitis optica.

    abstract:OBJECTIVE:The aim of this study was to report the frequency of autoimmune disorders and autoantibodies in 22 patients with neuromyelitis optica (NMO), as well as whether the seropositivity for autoantibodies differs between anti-aquaporin 4 (AQP4) positive and AQP4 negative NMO patients. METHODS:Demographic, medical r...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2016.49

    authors: Pereira WLCJ,Reiche EMV,Kallaur AP,Oliveira SR,Simão ANC,Lozovoy MAB,Schiavão LJV,Rodrigues PRDVP,Alfieri DF,Flauzino T,Kaimen-Maciel DR

    更新日期:2017-06-01 00:00:00

  • Safety, tolerability and efficacy of a rapid dose escalation of quetiapine in bipolar I mania: the FATIMA study.

    abstract:OBJECTIVE:The FATIMA study (FAst TItration of quetiapine fumarate in bipolar I MAnia) evaluated the safety, tolerability and efficacy of a rapid dose escalation of quetiapine in acutely ill bipolar I patients experiencing a manic episode. METHODS:In an open-label, phase II pilot study, 29 patients aged 18 years or old...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2009.00378.x

    authors: Constant E,Seghers A,Ranalli E,Ryckmans V,Snauwaert P,Parent M,Vandenhoven G

    更新日期:2009-06-01 00:00:00

  • In-patient treatment of borderline personality disorder: convergences and divergences between a psychoanalytical and a cognitive-behavioral approach.

    abstract::For more than 20 years, patients with borderline personality disorder have been treated as in-patients in the UC St-Jozef in Kortenberg, Belgium. The majority of these patients were treated in a psychoanalytical or a behavior therapy ward. During these years, the treatment programs of these wards were gradually adjust...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1034/j.1601-5215.2002.140206.x

    authors: Pieters G,Vermote R

    更新日期:2002-04-01 00:00:00

  • Characterisation and outcome of neuropsychiatric symptoms in patients with anti-NMDAR encephalitis.

    abstract:BACKGROUND:Encephalitis due to anti-N-methyl-D-aspartate receptor antibodies (ANMDARE) is the most frequent immune-mediated encephalitis. It is distinguished by the subacute onset of neuropsychiatric symptoms. OBJECTIVE:To evaluate the characteristic neuropsychiatric symptoms and their outcome in patients diagnosed wi...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2019.46

    authors: Restrepo-Martinez M,Ramirez-Bermudez J,Bayliss L,Espinola-Nadurille M

    更新日期:2020-04-01 00:00:00

  • Interferon, tryptophan and depression.

    abstract::Depression is a frequent comorbid disorder of many inflammatory diseases and it is suggested that brain inflammatory processes have a pathogenic role in mood dysregulation. Several immunocompromised patients have been treated with cytokines and long-term treatments have resulted in a variety of neuropsychiatric side-e...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1034/j.1601-5215.2003.00007.x

    authors: Fekkes D,Van Gool AR

    更新日期:2003-02-01 00:00:00

  • Reduced grey matter volume in frontal and temporal areas in depression: contributions from voxel-based morphometry study.

    abstract:OBJECTIVE:The aim of the current study was to examine whether and to what extent mood disorders, comprising major depression and bipolar disorder, are accompanied by structural changes in the brain as measured using voxel-based morphometry (VBM). METHODS:We performed a VBM study using a 3Т MRI system (GE Discovery 750...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2019.20

    authors: Kandilarova S,Stoyanov D,Sirakov N,Maes M,Specht K

    更新日期:2019-10-01 00:00:00

  • Possible association between G-protein β3 subunit C825T polymorphism and antipsychotic-induced restless legs syndrome in schizophrenia.

    abstract:OBJECTIVE:The incidence of restless legs syndrome (RLS) is presumed to be higher among people with schizophrenia who take antipsychotic medication, most of which blocks the dopamine D2 receptor. The purpose of this study was to determine whether the G-protein β3 subunit (GNB3) C825T polymorphism is associated with anti...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2007.00240.x

    authors: Kang SG,Lee HJ,Choi JE,Park JH,Lee SS,Han C,Kim YK,Kim SH,Lee MS,Joe SH,Jung IK,Kim L

    更新日期:2007-12-01 00:00:00

  • Involvement of NLRP3 inflammasome in schizophrenia-like behaviour in young animals after maternal immune activation.

    abstract:OBJECTIVE:To evaluate the involvement of nod-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome in schizophrenia-like behaviour in young animals exposed to maternal immune activation (MIA). METHODS:To this aim, on the 15th gestational day, the females received an injection of lipopolysaccharides. Whe...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2020.27

    authors: Ventura L,Freiberger V,Thiesen VB,Dias P,Dutra ML,Silva BB,Schlindwein AD,Comim CM

    更新日期:2020-12-01 00:00:00

  • Melatonine en stemmingsstoornissen.

    abstract::Melatonin is a hormone secreted by the pineal gland mainly during the night. The discovery that this melatonin secretion decreases under the influence of bright light, gave rise to the use of light therapy in some affective disorders. The literature on the relationship between melatonin secretion and mood is reviewed ...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/S0924270800037376

    authors: Beullens J

    更新日期:1995-09-01 00:00:00

  • Depression as first manifestation of a large intracerebral lymphoma.

    abstract:OBJECTIVE:The differentiation between a 'non-organic' depressive episode and an organic depressive disorder on the basis of clinical grounds might be challenging. METHODS:We report a case with an initially typical severe depressive episode without any focal neurological deficits. RESULTS:Only medical history from a t...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2013.19

    authors: Etgen T,Fleissner S

    更新日期:2013-08-01 00:00:00

  • Assessment of the hypothalamic-pituitary-adrenal axis activity: glucocorticoid receptor and mineralocorticoid receptor function in depression with early life stress - a systematic review.

    abstract:OBJECTIVE:The mechanisms involved in the dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, especially in the functioning of glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) in depressed patients, are not well elucidated. The objective of this study was to conduct a systematic review of art...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2011.00610.x

    authors: Von Werne Baes C,de Carvalho Tofoli SM,Martins CM,Juruena MF

    更新日期:2012-02-01 00:00:00

  • Gene polymorphisms and response to transcranial direct current stimulation for auditory verbal hallucinations in schizophrenia.

    abstract:OBJECTIVE:Recent observations demonstrate a significant ameliorative effect of add-on transcranial direct current stimulation (tDCS) on auditory verbal hallucinations (AVHs) in schizophrenia. Of the many SNPs, NRG1 rs35753505 and catechol-o-methyl transferase (COMT) rs4680 polymorphisms have shown to have a strong asso...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2018.4

    authors: Chhabra H,Shivakumar V,Subbanna M,Kalmady SV,Bose A,Agarwal SM,Sreeraj VS,Dinakaran D,Narayanaswamy JC,Debnath M,Venkatasubramanian G

    更新日期:2018-08-01 00:00:00

  • To what extent psychiatric patients feel involved in decision making about their mental health care? Relationships with socio-demographic, clinical, and psychological variables.

    abstract:BACKGROUND:Shared decision making (SDM) is an essential component of patient-centered care, but there is little information about its use in the psychiatric care. OBJECTIVE:To measure to what extent psychiatric patients feel they were involved in the process and steps of decision making about treatment choice and to a...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2014.21

    authors: De las Cuevas C,Peñate W

    更新日期:2014-12-01 00:00:00

  • Hyperventilation-stage electroencephalography in lateral temporal lobe epilepsy.

    abstract:BACKGROUND:To observe spike activity in electroencephalograms (EEGs), patients with symptomatic partial epilepsy are rarely monitored during the hyperventilation stages. CASE:A 38-year-old woman suffered from a ruptured arteriovenous malformation in the left temporal lobe. One and a half years later, the patient exper...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2007.00167.x

    authors: Asano S,Hara T

    更新日期:2007-02-01 00:00:00

  • Predicting medication non-adherence in severe affective disorders.

    abstract::Objective This study explored the utility of the Health Belief Models (HBM) in explaining medication adherence in subjects with severe affective disorders. Method Well established measuring instruments, with confirmed reliability and validity, were used to assess each component of two HBMs and adherence with mood stab...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/S0924270800035584

    authors: Scott J

    更新日期:2000-09-01 00:00:00

  • Effects of acute administration of mazindol on brain energy metabolism in adult mice.

    abstract:OBJECTIVES:Mazindol is a sympathomimetic amine, widely used as an anorectic agent in the treatment of obesity. This drug causes psychostimulant effects because of its pharmacological profile similar to amphetamine, acting like a monoamine reuptake inhibitor. However, the mechanisms underlying the action of mazindol are...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2013.43

    authors: Gonçalves CL,Scaini G,Rezin GT,Jeremias IC,Bez GD,Daufenbach JF,Gomes LM,Ferreira GK,Zugno AI,Streck EL

    更新日期:2014-06-01 00:00:00

  • Immunopathogenesis of multiple sclerosis.

    abstract::Immunopathogenesis of multiple sclerosis is a complex process involving T cell mediated autoimmunity at initial stage of disease. A long standing view that Th1 cells are critical for early inflammatory development of lesions is challenging by recent findings that Th1 helper cells with Th17 phenotype are even more impo...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/S0924270800032622

    authors: Brinar V

    更新日期:2009-06-01 00:00:00

  • A ventral prefrontal-amygdala neural system in bipolar disorder: a view from neuroimaging research.

    abstract::In the past decade, neuroimaging research has identified key components in the neural system that underlies bipolar disorder (BD). The ventral prefrontal cortex (VPFC) and amygdala are highly interconnected structures that jointly play a central role in emotional regulation. Numerous research groups have reported prom...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2009.00414.x

    authors: Womer FY,Kalmar JH,Wang F,Blumberg HP

    更新日期:2009-10-01 00:00:00

  • Standardised ginseng extract G115® potentiates the antidepressant-like properties of fluoxetine in the forced swim test.

    abstract:OBJECTIVE:Ginsenosides, biologically-active components of the root of Panax ginseng, have been reported to have therapeutic benefits in a number of disease states including psychiatric conditions such as major depressive disorder. Our objective was to determine if a standardized commercial ginseng extract, G115®, could...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2021.2

    authors: Terstege DJ,MacDonald DS,Tasker RA

    更新日期:2021-01-22 00:00:00

  • Recognition memory abnormalities in asymptomatic biological parents of a patient with schizophrenia.

    abstract:BACKGROUND:Recognition memory dysfunction has been frequently reported in schizophrenic populations, and has been linked with the development of delusions and thought disorder. A range of neuropsychological abnormalities have also been documented in the biological asymptomatic relatives of patients with schizophrenia; ...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1034/j.1601-5215.2003.00044.x

    authors: Edelstyn NM,Drakeford J,Oyebode F,Findlay CD

    更新日期:2003-10-01 00:00:00

  • Long chain omega-3 polyunsaturated fatty acids in the treatment of psychiatric illnesses in children and adolescents.

    abstract:OBJECTIVE:Long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) are in increasing use in the general population to treat health problems. The objective of the current article is to review the evidence for the rationale and benefit of LCn-3PUFA in the treatment of common psychiatric disorders in children and adoles...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2007.00189.x

    authors: Clayton EH,Hanstock TL,Garg ML,Hazell PL

    更新日期:2007-04-01 00:00:00

  • Functional recovery results from the risperidone long-acting injectable versus quetiapine relapse prevention trial (ConstaTRE).

    abstract:OBJECTIVE:ConstaTRE is an open-label, randomised, controlled, relapse prevention trial in patients with stable schizophrenia or schizoaffective disorder switched to risperidone long-acting injectable (RLAI) or oral quetiapine, and was designed to test the hypothesis that injectable antipsychotic treatment with risperid...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2013.7

    authors: Rouillon F,Eriksson L,Burba B,Raboch J,Kaprinis G,Schreiner A

    更新日期:2013-10-01 00:00:00

  • Use of social media and online dating among individuals with a history of affective disorder.

    abstract:OBJECTIVES:To investigate how individuals with a history of affective disorder use and perceive their use of social media and online dating. METHODS:A questionnaire focusing on affective disorders and the use of social media and online dating was handed out to outpatients from unipolar depression and bipolar disorder ...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2020.36

    authors: Rydahl KFK,Brund RBK,Medici CR,Hansen V,Straarup KN,Straszek SPV,Østergaard SD

    更新日期:2020-10-15 00:00:00

  • Cardiovasculaire adaptiviteit aan de verrichting van aandachts-taken bij kinderen met contact- en communicatieproblemen.

    abstract::A psychofysiological study of the cardiac adaptivity to attention-demanding reaction time tasks demonstrated that children with a lesser variant of the pervasive developmental disorder (DSM-IV: PDDNOS) exhibit less cardiac responsiveness to attention tasks than healthy children do. We studied changes in heart rate var...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/S092427080003605X

    authors: Althaus M,Aarnoudse CC,Mulder LJ,Mulder G,Minderaa RB

    更新日期:1999-09-01 00:00:00

  • Gender differences in socio-demographic, clinical characteristics and psychiatric diagnosis in/of suicide attempters in a Mexican population.

    abstract:OBJECTIVE:The aim of the present study was to analyse demographic and clinical characteristics, as well as psychiatric diagnoses to identify gender differences in patients with attempted suicide in a Mexican population. METHODS:Between September 2010 and September 2012, 140 suicide attempts were documented in the Depa...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2015.6

    authors: Fresán A,González-Castro TB,Peralta-Jiménez Y,Juárez-Rojop I,Pool-García S,Velázquez-Sánchez MP,López-Narváez L,Tovilla-Zárate CA

    更新日期:2015-06-01 00:00:00