Low IQ scores in schizophrenia: primary or secondary deficit?

abstract：:In this first part of a review on recent insights into the structure and function of the γ-aminobuty rie acid type A - benzodiazepine receptor system, the γ-aminobutyric acid type A (GABAA) receptor and the different types of benzodiazepine (BDZ) receptors known at this moment are dicussed. GABAA- and BDZ receptors ar...

journal_title：Acta neuropsychiatrica

authors： Vermeulen PJ,Zitman FG

更新日期：1996-09-01 00:00:00

abstract：:A psychofysiological study of the cardiac adaptivity to attention-demanding reaction time tasks demonstrated that children with a lesser variant of the pervasive developmental disorder (DSM-IV: PDDNOS) exhibit less cardiac responsiveness to attention tasks than healthy children do. We studied changes in heart rate var...

journal_title：Acta neuropsychiatrica

authors： Althaus M,Aarnoudse CC,Mulder LJ,Mulder G,Minderaa RB

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:The mechanisms involved in the dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, especially in the functioning of glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) in depressed patients, are not well elucidated. The objective of this study was to conduct a systematic review of art...

journal_title：Acta neuropsychiatrica

authors： Von Werne Baes C,de Carvalho Tofoli SM,Martins CM,Juruena MF

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Encephalitis due to anti-N-methyl-D-aspartate receptor antibodies (ANMDARE) is the most frequent immune-mediated encephalitis. It is distinguished by the subacute onset of neuropsychiatric symptoms. OBJECTIVE:To evaluate the characteristic neuropsychiatric symptoms and their outcome in patients diagnosed wi...

journal_title：Acta neuropsychiatrica

authors： Restrepo-Martinez M,Ramirez-Bermudez J,Bayliss L,Espinola-Nadurille M

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:ConstaTRE is an open-label, randomised, controlled, relapse prevention trial in patients with stable schizophrenia or schizoaffective disorder switched to risperidone long-acting injectable (RLAI) or oral quetiapine, and was designed to test the hypothesis that injectable antipsychotic treatment with risperid...

journal_title：Acta neuropsychiatrica

authors： Rouillon F,Eriksson L,Burba B,Raboch J,Kaprinis G,Schreiner A

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:This study aimed to explore effects of adjunctive treatment with N-acetyl cysteine (NAC) on markers of inflammation and neurogenesis in bipolar depression. METHODS:This is a secondary analysis of a placebo-controlled randomised trial. Serum samples were collected at baseline, week 8, and week 32 of the open-...

journal_title：Acta neuropsychiatrica

authors： Panizzutti B,Bortolasci C,Hasebe K,Kidnapillai S,Gray L,Walder K,Berk M,Mohebbi M,Dodd S,Gama C,Magalhães PV,Cotton SM,Kapczinski F,Bush AI,Malhi GS,Dean OM

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the involvement of nod-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome in schizophrenia-like behaviour in young animals exposed to maternal immune activation (MIA). METHODS:To this aim, on the 15th gestational day, the females received an injection of lipopolysaccharides. Whe...

journal_title：Acta neuropsychiatrica

authors： Ventura L,Freiberger V,Thiesen VB,Dias P,Dutra ML,Silva BB,Schlindwein AD,Comim CM

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to report the frequency of autoimmune disorders and autoantibodies in 22 patients with neuromyelitis optica (NMO), as well as whether the seropositivity for autoantibodies differs between anti-aquaporin 4 (AQP4) positive and AQP4 negative NMO patients. METHODS:Demographic, medical r...

journal_title：Acta neuropsychiatrica

authors： Pereira WLCJ,Reiche EMV,Kallaur AP,Oliveira SR,Simão ANC,Lozovoy MAB,Schiavão LJV,Rodrigues PRDVP,Alfieri DF,Flauzino T,Kaimen-Maciel DR

更新日期：2017-06-01 00:00:00

abstract：:Since the description of SAD the prevalence of this disorder has been of particular interest. The more so, because early studies, indicated the correctness of the on theoretical grounds - expected interaction between latitude and prevalence rate of SAD. More eleborate prevalence studies, mainly in the USA indeed showe...

journal_title：Acta neuropsychiatrica

authors： Mersch PP,Middendorp H,Bouhuys AL,Beersma DG,van den Hoofdakker RH

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:To develop and test a novel fMRI compatible comprehensive and expressive language task that reliably and predictably activates both Wernicke's and Broca's cortical brain regions, respectively, and has utility for the determination of hemispheric language dominance. METHODS:Ten healthy men (seven) and women (...

journal_title：Acta neuropsychiatrica

authors： Berntsen EM,Rasmussen IA,Samuelsen P,Xu J,Haraldseth O,Lagopoulos J,Malhi GS

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:The differentiation between a 'non-organic' depressive episode and an organic depressive disorder on the basis of clinical grounds might be challenging. METHODS:We report a case with an initially typical severe depressive episode without any focal neurological deficits. RESULTS:Only medical history from a t...

journal_title：Acta neuropsychiatrica

authors： Etgen T,Fleissner S

更新日期：2013-08-01 00:00:00

abstract：:BACKGROUND: Aberrant electrophysiological and hemodynamic processing of auditory oddball stimuli is among the most robustly documented findings in patients with schizophrenia. However, no study to date has directly examined linked patterns of electrical and hemodynamic differences in patients and controls. METHODS: I...

journal_title：Acta neuropsychiatrica

authors： Calhoun V,Wu L,Kiehl K,Eichele T,Pearlson G

更新日期：2010-06-01 00:00:00

abstract：:Melatonin is a hormone secreted by the pineal gland mainly during the night. The discovery that this melatonin secretion decreases under the influence of bright light, gave rise to the use of light therapy in some affective disorders. The literature on the relationship between melatonin secretion and mood is reviewed ...

journal_title：Acta neuropsychiatrica

authors： Beullens J

更新日期：1995-09-01 00:00:00

abstract：:The alterations in the inflammatory response system (IRS) appear to be quite different between OCD and anorexia nervosa and are also different from the changes observed in major depression. In anorexia nervosa, there is some evidence for increased production of monocytic cytokines, i.e. tumor necrosis factor-α (TNFα) ...

journal_title：Acta neuropsychiatrica

authors： van West D,Maes M

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:The aim of the current study was to examine whether and to what extent mood disorders, comprising major depression and bipolar disorder, are accompanied by structural changes in the brain as measured using voxel-based morphometry (VBM). METHODS:We performed a VBM study using a 3Т MRI system (GE Discovery 750...

journal_title：Acta neuropsychiatrica

authors： Kandilarova S,Stoyanov D,Sirakov N,Maes M,Specht K

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Recent observations demonstrate a significant ameliorative effect of add-on transcranial direct current stimulation (tDCS) on auditory verbal hallucinations (AVHs) in schizophrenia. Of the many SNPs, NRG1 rs35753505 and catechol-o-methyl transferase (COMT) rs4680 polymorphisms have shown to have a strong asso...

journal_title：Acta neuropsychiatrica

authors： Chhabra H,Shivakumar V,Subbanna M,Kalmady SV,Bose A,Agarwal SM,Sreeraj VS,Dinakaran D,Narayanaswamy JC,Debnath M,Venkatasubramanian G

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:To observe spike activity in electroencephalograms (EEGs), patients with symptomatic partial epilepsy are rarely monitored during the hyperventilation stages. CASE:A 38-year-old woman suffered from a ruptured arteriovenous malformation in the left temporal lobe. One and a half years later, the patient exper...

journal_title：Acta neuropsychiatrica

authors： Asano S,Hara T

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:Post-traumatic stress disorder (PTSD) displays high co-morbidity with major depression and treatment-resistant depression (TRD). Earlier work demonstrated exaggerated depressive-like symptoms in a gene×environment model of TRD and an abrogated response to imipramine. We extended the investigation by studying ...

journal_title：Acta neuropsychiatrica

authors： Brand SJ,Harvey BH

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Ginsenosides, biologically-active components of the root of Panax ginseng, have been reported to have therapeutic benefits in a number of disease states including psychiatric conditions such as major depressive disorder. Our objective was to determine if a standardized commercial ginseng extract, G115®, could...

journal_title：Acta neuropsychiatrica

authors： Terstege DJ,MacDonald DS,Tasker RA

更新日期：2021-01-22 00:00:00

abstract：BACKGROUND:Sleep disorders are widespread among patients with schizophrenia and contribute to adverse clinical outcomes. Antipsychotic drugs exert varying effects on sleep, and the effects of atypical agents may differ from those of conventional neuroleptics. OBJECTIVE:To review the literature on the effects of atypic...

journal_title：Acta neuropsychiatrica

authors： Haffmans PM,Oolders HJ,Hoencamp E,Schreiner A

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:Pain perception is reported to be altered in patients with depression and schizophrenia. However, few studies have investigated the pain perception in patients with bipolar disorders. We therefore aimed to compare pain sensitivity between patients with bipolar disorder, schizophrenia and controls. METHODS:St...

journal_title：Acta neuropsychiatrica

authors： Atik L,Konuk N,Akay O,Ozturk D,Erdogan A

更新日期：2007-10-01 00:00:00

abstract：UNLABELLED:Scheuch K, Bräunig P, Gauggel S, Kliesow K, Sarkar R, Krüger S. Emotional vulnerability and cognitive control in patients with bipolar disorder and their healthy siblings: a pilot study. OBJECTIVE:There is evidence that, even in remission, patients with bipolar disorder (BD) have deficits in cognitive funct...

journal_title：Acta neuropsychiatrica

authors： Houshmand K,Bräunig P,Gauggel S,Kliesow K,Sarkar R,Krüger S

更新日期：2010-04-01 00:00:00

abstract：:Neuroleptic malignant syndrome (NMS) is associated with the administration of antipsychotic agents and other drugs such as l-dopa, antidepressants, and antihistaminic agents. Unexpected changes in mental status, new-onset catatonia, episodic tachycardia, tachypnea, hypertension, dysarthria, dysphagia, diaphoresis, sia...

journal_title：Acta neuropsychiatrica

authors： Ananth J,Aduri K,Parameswaran S,Gunatilake S

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:Long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) are in increasing use in the general population to treat health problems. The objective of the current article is to review the evidence for the rationale and benefit of LCn-3PUFA in the treatment of common psychiatric disorders in children and adoles...

journal_title：Acta neuropsychiatrica

authors： Clayton EH,Hanstock TL,Garg ML,Hazell PL

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Female patients with anorexia nervosa differ significantly from the control women in various dimensions of personality. OBJECTIVE:To investigate the personality dimensions measured with the Temperament and Character Inventory (TCI) in adolescent patients with restrictive-type and bulimic/purging-type anorex...

journal_title：Acta neuropsychiatrica

authors： Rybakowski F,Slopien A,Zakrzewska M,Hornowska E,Rajewski A

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVES:To investigate how individuals with a history of affective disorder use and perceive their use of social media and online dating. METHODS:A questionnaire focusing on affective disorders and the use of social media and online dating was handed out to outpatients from unipolar depression and bipolar disorder ...

journal_title：Acta neuropsychiatrica

authors： Rydahl KFK,Brund RBK,Medici CR,Hansen V,Straarup KN,Straszek SPV,Østergaard SD

更新日期：2020-10-15 00:00:00

abstract：OBJECTIVE:To determine the prevalence of and factors associated with depression and stress with perceived quality of life and the salivary cortisol levels in Community Health Agent (CHA). Materials and Methods Cross-sectional descriptive study of CHAs in Pelotas-RS, Brazil. Data collection, including sociodemographic i...

journal_title：Acta neuropsychiatrica

authors： Knuth BS,Cocco RA,Radtke VA,Medeiros JR,Oses JP,Wiener CD,Jansen K

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:The incidence of restless legs syndrome (RLS) is presumed to be higher among people with schizophrenia who take antipsychotic medication, most of which blocks the dopamine D2 receptor. The purpose of this study was to determine whether the G-protein β3 subunit (GNB3) C825T polymorphism is associated with anti...

journal_title：Acta neuropsychiatrica

authors： Kang SG,Lee HJ,Choi JE,Park JH,Lee SS,Han C,Kim YK,Kim SH,Lee MS,Joe SH,Jung IK,Kim L

更新日期：2007-12-01 00:00:00

abstract：:In two previous letters on an selective serotonin reuptake inhibitor (SSRI) meta-analysis conducted by the Copenhagen Trial Unit at Copenhagen University Hospital, we have commented on a large number of errors, almost all of which have tilted the results in an anti-drug direction, that unfortunately mar this publicati...

journal_title：Acta neuropsychiatrica

authors： Hieronymus F,Lisinski A,Näslund J,Eriksson E

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:Fas (CD95), commonly categorised as a death receptor due to its well-defined role in apoptosis, can paradoxically also promote neuroprotection. We have previously found that defects in Fas signalling render mice highly susceptible to neural degeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mous...

journal_title：Acta neuropsychiatrica

authors： Landau AM,Siegrist-Johnstone R,Desbarats J

更新日期：2012-06-01 00:00:00