The prospects of new antipsychotic principles.

abstract：:Immunopathogenesis of multiple sclerosis is a complex process involving T cell mediated autoimmunity at initial stage of disease. A long standing view that Th1 cells are critical for early inflammatory development of lesions is challenging by recent findings that Th1 helper cells with Th17 phenotype are even more impo...

journal_title：Acta neuropsychiatrica

authors： Brinar V

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To review the literature comparing electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS) for major depression. METHODS:Data from the six randomised, prospective studies were agglutinated into one data set. Special attention was given to the methods of both TMS and ECT as well as data pe...

journal_title：Acta neuropsychiatrica

authors： Rasmussen KG

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:This study used a prospective design and the technique of structural modelling to examine the complex interrelations between psychological factors, immune status and complications after major surgery. METHODS:Twenty-nine women scheduled for elective cholecystectomy were studied prospectively. Information reg...

journal_title：Acta neuropsychiatrica

authors： Vollmer-Conna U,Bird KD,Yeo BW,Truskett PG,Westbrook RF,Wakefield D

更新日期：2009-08-01 00:00:00

abstract：:Depressive syndromes are a group of heterogeneous disorders. Atypical depression (AD) with reversed vegetative signs, such as hyperphagia or hypersomnia, is traditionally neglected, demonstrated by the fact that in the most widely used depression scales, such as the Hamilton Depression Scale (HAMD), melancholic sympto...

journal_title：Acta neuropsychiatrica

authors： Murck H

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:The aims of this study were to determine the dominant affective temperament changes in stroke survivors and whether temperament affects the disability. METHODS:A total of 63 stroke patients were included in this study. Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire was used to...

journal_title：Acta neuropsychiatrica

authors： Kurt E,Karacan I,Ozaras N,Alatas G

更新日期：2008-12-01 00:00:00

abstract：:Most forms of behaviour whether normal or abnormal, show a tendency to run in families. However, these can range from symptoms of dementia and movement disorder caused by the comparatively rare autosomal dominant Huntington's disease to common everyday aspects of behaviour such as religious persuasion or career choice...

journal_title：Acta neuropsychiatrica

authors： McGuffin P

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVES:Disturbances in the noradrenergic system, including alterations in the densities of α2-adrenoceptors, are posited to be involved in the pathophysiology of depression. In this study, we investigate the binding of α2-adrenoceptors in regions relevant to depression in an animal model of depression. METHODS:Usi...

journal_title：Acta neuropsychiatrica

authors： Lillethorup TP,Iversen P,Wegener G,Doudet DJ,Landau AM

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Female patients with anorexia nervosa differ significantly from the control women in various dimensions of personality. OBJECTIVE:To investigate the personality dimensions measured with the Temperament and Character Inventory (TCI) in adolescent patients with restrictive-type and bulimic/purging-type anorex...

journal_title：Acta neuropsychiatrica

authors： Rybakowski F,Slopien A,Zakrzewska M,Hornowska E,Rajewski A

更新日期：2004-06-01 00:00:00

abstract：:Het is al lang bekend dat het optreden van ontwikke-lingsmijlpalen sterk van baby tot baby kan verschillen. Theorieën of modellen die daarentegen een strakke timing, gepaard gaande met geringe individuele verschillen, voor ontwikkelingsverschijnselen postuleren, hebben dan ook een zware bewijslast te torsen. Het model...

journal_title：Acta neuropsychiatrica

authors： van Geert P,de Weerth C

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVES:To investigate how individuals with a history of affective disorder use and perceive their use of social media and online dating. METHODS:A questionnaire focusing on affective disorders and the use of social media and online dating was handed out to outpatients from unipolar depression and bipolar disorder ...

journal_title：Acta neuropsychiatrica

authors： Rydahl KFK,Brund RBK,Medici CR,Hansen V,Straarup KN,Straszek SPV,Østergaard SD

更新日期：2020-10-15 00:00:00

abstract：OBJECTIVE:Prisoners categorised as 'dangerous' are a category of prisoners that require and/or force into using special measures of caution, protection and security. The aim of the study was to examine the intensity of anxiety (as a state and as a trait) experienced by officers working with 'dangerous' prisoners and st...

journal_title：Acta neuropsychiatrica

authors： Tsirigotis K,Gruszczyński W,Pęczkowski S

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:Schizoaffective disorder is a disease with both affective and psychotic symptoms. In this study, we aimed to compare oxidative metabolism markers of schizoaffective disorder, bipolar disorder and schizophrenic patients. Furthermore, we also aimed to investigate whether schizoaffective disorder could be differ...

journal_title：Acta neuropsychiatrica

authors： Bulbul F,Virit O,Alpak G,Unal A,Bulut M,Kaya MC,Altindag A,Celik H,Savas HA

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of and factors associated with depression and stress with perceived quality of life and the salivary cortisol levels in Community Health Agent (CHA). Materials and Methods Cross-sectional descriptive study of CHAs in Pelotas-RS, Brazil. Data collection, including sociodemographic i...

journal_title：Acta neuropsychiatrica

authors： Knuth BS,Cocco RA,Radtke VA,Medeiros JR,Oses JP,Wiener CD,Jansen K

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:The incidence of restless legs syndrome (RLS) is presumed to be higher among people with schizophrenia who take antipsychotic medication, most of which blocks the dopamine D2 receptor. The purpose of this study was to determine whether the G-protein β3 subunit (GNB3) C825T polymorphism is associated with anti...

journal_title：Acta neuropsychiatrica

authors： Kang SG,Lee HJ,Choi JE,Park JH,Lee SS,Han C,Kim YK,Kim SH,Lee MS,Joe SH,Jung IK,Kim L

更新日期：2007-12-01 00:00:00

abstract：:The alterations in the inflammatory response system (IRS) appear to be quite different between OCD and anorexia nervosa and are also different from the changes observed in major depression. In anorexia nervosa, there is some evidence for increased production of monocytic cytokines, i.e. tumor necrosis factor-α (TNFα) ...

journal_title：Acta neuropsychiatrica

authors： van West D,Maes M

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:To investigate oxidative stress parameters [total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), paraoxonase (PON), arylesterase (ARE) and thiol-disulphide homeostasis] in patients who were diagnosed as having somatic symptom disorder in accordance with Diagnostic and Stat...

journal_title：Acta neuropsychiatrica

authors： Kabadayi Sahin E,Caykoylu A,Senat A,Erel O

更新日期：2018-12-18 00:00:00

abstract：OBJECTIVE:There is clear evidence of a genetic component in major depression, and several studies indicate that neuropeptide Y (NPY) could play an important role in the pathophysiology of the disease. A well-known polymorphism encoding the substitution of leucine to proline in the signal peptide sequence of NPY (Leu7Pr...

journal_title：Acta neuropsychiatrica

authors： Koefoed P,Woldbye DP,Hansen TV,Eplov LF,Christiansen SH,Mors O,Kessing LV,Werge T,Kaipio K,Pesonen U,Fahmy T,Mellerup E,Jakobsen KD,Hansen ES,Knudsen GM,Bukh JD,Bock C,Lindberg C,Kristensen AS,Dam H,Nordentoft M,

更新日期：2012-04-01 00:00:00

abstract：:The elucidation of sleep regulation is not an easy task. On one side, there is a multitude of solid yet disparate data, on the other side, the topic is tempting for engaging in wild speculation, particularly with respect to the functions of sleep. Models may exert a moderating influence by mediating between the two ex...

journal_title：Acta neuropsychiatrica

authors： Borbély AA

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to report the frequency of autoimmune disorders and autoantibodies in 22 patients with neuromyelitis optica (NMO), as well as whether the seropositivity for autoantibodies differs between anti-aquaporin 4 (AQP4) positive and AQP4 negative NMO patients. METHODS:Demographic, medical r...

journal_title：Acta neuropsychiatrica

authors： Pereira WLCJ,Reiche EMV,Kallaur AP,Oliveira SR,Simão ANC,Lozovoy MAB,Schiavão LJV,Rodrigues PRDVP,Alfieri DF,Flauzino T,Kaimen-Maciel DR

更新日期：2017-06-01 00:00:00

abstract：:In the past decade, neuroimaging research has identified key components in the neural system that underlies bipolar disorder (BD). The ventral prefrontal cortex (VPFC) and amygdala are highly interconnected structures that jointly play a central role in emotional regulation. Numerous research groups have reported prom...

journal_title：Acta neuropsychiatrica

authors： Womer FY,Kalmar JH,Wang F,Blumberg HP

更新日期：2009-09-23 00:00:00

abstract：BACKGROUND:Encephalitis due to anti-N-methyl-D-aspartate receptor antibodies (ANMDARE) is the most frequent immune-mediated encephalitis. It is distinguished by the subacute onset of neuropsychiatric symptoms. OBJECTIVE:To evaluate the characteristic neuropsychiatric symptoms and their outcome in patients diagnosed wi...

journal_title：Acta neuropsychiatrica

authors： Restrepo-Martinez M,Ramirez-Bermudez J,Bayliss L,Espinola-Nadurille M

更新日期：2020-04-01 00:00:00

abstract：UNLABELLED:Scheuch K, Bräunig P, Gauggel S, Kliesow K, Sarkar R, Krüger S. Emotional vulnerability and cognitive control in patients with bipolar disorder and their healthy siblings: a pilot study. OBJECTIVE:There is evidence that, even in remission, patients with bipolar disorder (BD) have deficits in cognitive funct...

journal_title：Acta neuropsychiatrica

authors： Houshmand K,Bräunig P,Gauggel S,Kliesow K,Sarkar R,Krüger S

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:ConstaTRE is an open-label, randomised, controlled, relapse prevention trial in patients with stable schizophrenia or schizoaffective disorder switched to risperidone long-acting injectable (RLAI) or oral quetiapine, and was designed to test the hypothesis that injectable antipsychotic treatment with risperid...

journal_title：Acta neuropsychiatrica

authors： Rouillon F,Eriksson L,Burba B,Raboch J,Kaprinis G,Schreiner A

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Recognition memory dysfunction has been frequently reported in schizophrenic populations, and has been linked with the development of delusions and thought disorder. A range of neuropsychological abnormalities have also been documented in the biological asymptomatic relatives of patients with schizophrenia; ...

journal_title：Acta neuropsychiatrica

authors： Edelstyn NM,Drakeford J,Oyebode F,Findlay CD

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:Fas (CD95), commonly categorised as a death receptor due to its well-defined role in apoptosis, can paradoxically also promote neuroprotection. We have previously found that defects in Fas signalling render mice highly susceptible to neural degeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mous...

journal_title：Acta neuropsychiatrica

authors： Landau AM,Siegrist-Johnstone R,Desbarats J

更新日期：2012-06-01 00:00:00

abstract：:Fatigue is a common problem; when chronic and disabling, subjects can be categorized as having chronic fatigue syndrome (CFS). Whilst it is most likely a multifactorial condition of biopsychosocial origin, the nature of the pathophysiological component remains unclear. There has been a wealth of interest in the possib...

journal_title：Acta neuropsychiatrica

authors： Cleare AJ

更新日期：2003-12-01 00:00:00

abstract：:BACKGROUND: Aberrant electrophysiological and hemodynamic processing of auditory oddball stimuli is among the most robustly documented findings in patients with schizophrenia. However, no study to date has directly examined linked patterns of electrical and hemodynamic differences in patients and controls. METHODS: I...

journal_title：Acta neuropsychiatrica

authors： Calhoun V,Wu L,Kiehl K,Eichele T,Pearlson G

更新日期：2010-06-01 00:00:00

abstract：:A huge number of natural and synthetic compounds modulate the function of the γ-aminobutyric acid type A receptor (GABAA-R) by interacting with several allosteric binding sites which may differ in the various GABAA-R subtypes. The benzodiazepine receptor (BDZ-R) is the most intensively studied allosteric site. It is t...

journal_title：Acta neuropsychiatrica

authors： Vermeulen PJ,Zitman FG

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE:Pain perception is reported to be altered in patients with depression and schizophrenia. However, few studies have investigated the pain perception in patients with bipolar disorders. We therefore aimed to compare pain sensitivity between patients with bipolar disorder, schizophrenia and controls. METHODS:St...

journal_title：Acta neuropsychiatrica

authors： Atik L,Konuk N,Akay O,Ozturk D,Erdogan A

更新日期：2007-10-01 00:00:00

abstract：:Neuroleptic malignant syndrome (NMS) is associated with the administration of antipsychotic agents and other drugs such as l-dopa, antidepressants, and antihistaminic agents. Unexpected changes in mental status, new-onset catatonia, episodic tachycardia, tachypnea, hypertension, dysarthria, dysphagia, diaphoresis, sia...

journal_title：Acta neuropsychiatrica

authors： Ananth J,Aduri K,Parameswaran S,Gunatilake S

更新日期：2004-08-01 00:00:00