Recognition memory abnormalities in asymptomatic biological parents of a patient with schizophrenia.

Abstract:

BACKGROUND:Recognition memory dysfunction has been frequently reported in schizophrenic populations, and has been linked with the development of delusions and thought disorder. A range of neuropsychological abnormalities have also been documented in the biological asymptomatic relatives of patients with schizophrenia; however, recognition memory has not been one of them. AIM:This study was carried out in order to investigate: (i) verbal and facial recognition memory in terms of accuracy and false alarm rates; and (ii) contributions from the episodic and semantic memory systems to recognition memory, in the biological asymptomatic parents of a reported schizophrenic patient and a set of male and female psychotic controls. RESULTS:Gender differences failed to emerge between the psychotic controls on any of the recognition measures (discrimination accuracy, response bias, hit and false alarm rates, 'remember' and 'know' recognition memory decisions). However, there was evidence of recognition dysfunction in the female relative, and to a lesser extent, in the male. Both parent's recognition memory performance profiles were marked by a pathologically elevated false alarm rate, and an increased dependence 'remember' judgements, i.e. input from the episodic memory system, to drive recognition memory decisions. CONCLUSIONS:These findings are discussed in the context of models of episodic and semantic memory impairment in schizophrenia.

journal_name

Acta Neuropsychiatr

journal_title

Acta neuropsychiatrica

authors

Edelstyn NM,Drakeford J,Oyebode F,Findlay CD

doi

10.1034/j.1601-5215.2003.00044.x

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

296-303

issue

5

eissn

0924-2708

issn

1601-5215

pii

S0924270800004361

journal_volume

15

pub_type

杂志文章
  • The long-term impact of bereavement upon spouse health: a 10-year follow-up.

    abstract:UNLABELLED:Jones MP, Bartrop RW, Forcier L, Penny R. The long-term impact of bereavement upon spouse health: a 10-year follow-up. OBJECTIVES:This study is the first to examine the effect of bereavement of a first-degree family member on subsequent morbidity over a 10-year follow-up period. METHODS:A sample of bereave...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2010.00482.x

    authors: Jones MP,Bartrop RW,Forcier L,Penny R

    更新日期:2010-10-01 00:00:00

  • Depression as first manifestation of a large intracerebral lymphoma.

    abstract:OBJECTIVE:The differentiation between a 'non-organic' depressive episode and an organic depressive disorder on the basis of clinical grounds might be challenging. METHODS:We report a case with an initially typical severe depressive episode without any focal neurological deficits. RESULTS:Only medical history from a t...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2013.19

    authors: Etgen T,Fleissner S

    更新日期:2013-08-01 00:00:00

  • Temperament and Character Inventory (TCI) in adolescents with anorexia nervosa.

    abstract:BACKGROUND:Female patients with anorexia nervosa differ significantly from the control women in various dimensions of personality. OBJECTIVE:To investigate the personality dimensions measured with the Temperament and Character Inventory (TCI) in adolescent patients with restrictive-type and bulimic/purging-type anorex...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.0924-2708.2004.00073.x

    authors: Rybakowski F,Slopien A,Zakrzewska M,Hornowska E,Rajewski A

    更新日期:2004-06-01 00:00:00

  • Predicting medication non-adherence in severe affective disorders.

    abstract::Objective This study explored the utility of the Health Belief Models (HBM) in explaining medication adherence in subjects with severe affective disorders. Method Well established measuring instruments, with confirmed reliability and validity, were used to assess each component of two HBMs and adherence with mood stab...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/S0924270800035584

    authors: Scott J

    更新日期:2000-09-01 00:00:00

  • BDNF and S100B in psychotic disorders: evidence for an association with treatment responsiveness.

    abstract:OBJECTIVE:Brain-derived neurotrophic factor (BDNF) and S100B are involved in brain plasticity processes and their serum levels have been demonstrated to be altered in patients with psychoses. This study aimed to identify subgroups of patients with psychotic disorders across diagnostic boundaries that show a specific sy...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2013.59

    authors: van de Kerkhof NW,Fekkes D,van der Heijden FM,Verhoeven WM

    更新日期:2014-08-01 00:00:00

  • Adjunctive cognitive remediation for schizophrenia using yoga: an open, non-randomized trial.

    abstract::BACKGROUND: Yoga therapy (YT) improves cognitive function in healthy individuals, but its impact on cognitive function among persons with schizophrenia (SZ) has not been investigated. AIMS: Evaluate adjunctive YT for cognitive domains impaired in SZ. METHODS: Patients with SZ received YT or treatment as usual (TAU; ...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2011.00587.x

    authors: Bhatia T,Agarwal A,Shah G,Wood J,Richard J,Gur RE,Gur RC,Nimgaonkar VL,Mazumdar S,Deshpande SN

    更新日期:2012-04-01 00:00:00

  • Effects of acute administration of mazindol on brain energy metabolism in adult mice.

    abstract:OBJECTIVES:Mazindol is a sympathomimetic amine, widely used as an anorectic agent in the treatment of obesity. This drug causes psychostimulant effects because of its pharmacological profile similar to amphetamine, acting like a monoamine reuptake inhibitor. However, the mechanisms underlying the action of mazindol are...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2013.43

    authors: Gonçalves CL,Scaini G,Rezin GT,Jeremias IC,Bez GD,Daufenbach JF,Gomes LM,Ferreira GK,Zugno AI,Streck EL

    更新日期:2014-06-01 00:00:00

  • Involvement of NLRP3 inflammasome in schizophrenia-like behaviour in young animals after maternal immune activation.

    abstract:OBJECTIVE:To evaluate the involvement of nod-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome in schizophrenia-like behaviour in young animals exposed to maternal immune activation (MIA). METHODS:To this aim, on the 15th gestational day, the females received an injection of lipopolysaccharides. Whe...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2020.27

    authors: Ventura L,Freiberger V,Thiesen VB,Dias P,Dutra ML,Silva BB,Schlindwein AD,Comim CM

    更新日期:2020-12-01 00:00:00

  • Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression.

    abstract:OBJECTIVE:There is clear evidence of a genetic component in major depression, and several studies indicate that neuropeptide Y (NPY) could play an important role in the pathophysiology of the disease. A well-known polymorphism encoding the substitution of leucine to proline in the signal peptide sequence of NPY (Leu7Pr...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2011.00600.x

    authors: Koefoed P,Woldbye DP,Hansen TV,Eplov LF,Christiansen SH,Mors O,Kessing LV,Werge T,Kaipio K,Pesonen U,Fahmy T,Mellerup E,Jakobsen KD,Hansen ES,Knudsen GM,Bukh JD,Bock C,Lindberg C,Kristensen AS,Dam H,Nordentoft M,

    更新日期:2012-04-01 00:00:00

  • A ventral prefrontal-amygdala neural system in bipolar disorder: a view from neuroimaging research.

    abstract::In the past decade, neuroimaging research has identified key components in the neural system that underlies bipolar disorder (BD). The ventral prefrontal cortex (VPFC) and amygdala are highly interconnected structures that jointly play a central role in emotional regulation. Numerous research groups have reported prom...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2009.00414.x

    authors: Womer FY,Kalmar JH,Wang F,Blumberg HP

    更新日期:2009-10-01 00:00:00

  • The prospects of new antipsychotic principles.

    abstract::Biological schizophrenia research has been dominated by the dopamine hypothesis for decades, but in recent years a more diversified view has gained increasing attention. Several neurotransmitters are now being discussed, and especially their interaction in complex circuitries. The demonstration of an atypical profile ...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/S0924270800036838

    authors: Carlsson A

    更新日期:1997-06-01 00:00:00

  • Glucocorticoids and glucocorticoid receptors: mediators of fatigue?

    abstract::Fatigue is a common problem; when chronic and disabling, subjects can be categorized as having chronic fatigue syndrome (CFS). Whilst it is most likely a multifactorial condition of biopsychosocial origin, the nature of the pathophysiological component remains unclear. There has been a wealth of interest in the possib...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1046/j.1601-5215.2003.00050.x

    authors: Cleare AJ

    更新日期:2003-12-01 00:00:00

  • Good news regarding SSRI safety in Danish meta-analysis.

    abstract::In two previous letters on an selective serotonin reuptake inhibitor (SSRI) meta-analysis conducted by the Copenhagen Trial Unit at Copenhagen University Hospital, we have commented on a large number of errors, almost all of which have tilted the results in an anti-drug direction, that unfortunately mar this publicati...

    journal_title:Acta neuropsychiatrica

    pub_type: 评论,杂志文章

    doi:10.1017/neu.2019.42

    authors: Hieronymus F,Lisinski A,Näslund J,Eriksson E

    更新日期:2020-02-01 00:00:00

  • Neuroleptic malignant syndrome: risk factors, pathophysiology, and treatment.

    abstract::Neuroleptic malignant syndrome (NMS) is associated with the administration of antipsychotic agents and other drugs such as l-dopa, antidepressants, and antihistaminic agents. Unexpected changes in mental status, new-onset catatonia, episodic tachycardia, tachypnea, hypertension, dysarthria, dysphagia, diaphoresis, sia...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.0924-2708.2004.00085.x

    authors: Ananth J,Aduri K,Parameswaran S,Gunatilake S

    更新日期:2004-08-01 00:00:00

  • Possible association between G-protein β3 subunit C825T polymorphism and antipsychotic-induced restless legs syndrome in schizophrenia.

    abstract:OBJECTIVE:The incidence of restless legs syndrome (RLS) is presumed to be higher among people with schizophrenia who take antipsychotic medication, most of which blocks the dopamine D2 receptor. The purpose of this study was to determine whether the G-protein β3 subunit (GNB3) C825T polymorphism is associated with anti...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2007.00240.x

    authors: Kang SG,Lee HJ,Choi JE,Park JH,Lee SS,Han C,Kim YK,Kim SH,Lee MS,Joe SH,Jung IK,Kim L

    更新日期:2007-12-01 00:00:00

  • Comparing running therapy with physiotraining therapy in the treatment of mood disorders.

    abstract:BACKGROUND:Despite various studies, supportive evidence for the efficacy of exercise in treatment of mental illness is still weak. OBJECTIVE:The aim of this study was to compare two forms of exercise, namely running therapy (RT) and physiotraining therapy (PT), on stationary devices. METHODS:Patients in a day treatme...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2006.00115.x

    authors: Judith Haffmans PM,Kleinsman AC,van Weelden C,Huijbrechts IP,Hoencamp E

    更新日期:2006-06-01 00:00:00

  • Immunopathogenesis of multiple sclerosis.

    abstract::Immunopathogenesis of multiple sclerosis is a complex process involving T cell mediated autoimmunity at initial stage of disease. A long standing view that Th1 cells are critical for early inflammatory development of lesions is challenging by recent findings that Th1 helper cells with Th17 phenotype are even more impo...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/S0924270800032622

    authors: Brinar V

    更新日期:2009-06-01 00:00:00

  • Frequency of autoimmune disorders and autoantibodies in patients with neuromyelitis optica.

    abstract:OBJECTIVE:The aim of this study was to report the frequency of autoimmune disorders and autoantibodies in 22 patients with neuromyelitis optica (NMO), as well as whether the seropositivity for autoantibodies differs between anti-aquaporin 4 (AQP4) positive and AQP4 negative NMO patients. METHODS:Demographic, medical r...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2016.49

    authors: Pereira WLCJ,Reiche EMV,Kallaur AP,Oliveira SR,Simão ANC,Lozovoy MAB,Schiavão LJV,Rodrigues PRDVP,Alfieri DF,Flauzino T,Kaimen-Maciel DR

    更新日期:2017-06-01 00:00:00

  • α2-adrenoceptor binding in Flinders-sensitive line compared with Flinders-resistant line and Sprague-Dawley rats.

    abstract:OBJECTIVES:Disturbances in the noradrenergic system, including alterations in the densities of α2-adrenoceptors, are posited to be involved in the pathophysiology of depression. In this study, we investigate the binding of α2-adrenoceptors in regions relevant to depression in an animal model of depression. METHODS:Usi...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2015.24

    authors: Lillethorup TP,Iversen P,Wegener G,Doudet DJ,Landau AM

    更新日期:2015-12-01 00:00:00

  • In-patient treatment of borderline personality disorder: convergences and divergences between a psychoanalytical and a cognitive-behavioral approach.

    abstract::For more than 20 years, patients with borderline personality disorder have been treated as in-patients in the UC St-Jozef in Kortenberg, Belgium. The majority of these patients were treated in a psychoanalytical or a behavior therapy ward. During these years, the treatment programs of these wards were gradually adjust...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1034/j.1601-5215.2002.140206.x

    authors: Pieters G,Vermote R

    更新日期:2002-04-01 00:00:00

  • Changes in immune and endocrine systems in posttraumatic stress disorder - prospective study.

    abstract:INTRODUCTION AND AIM:Posttraumatic stress disorder (PTSD) is associated with increased medical morbidity, particularly from the autoimmune and cardiovascular diseases. Changes in the endocrine and immune system are key mediators in this process. The aim of our study was to investigate weather hormones (cortisol and pro...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/S0924270800032725

    authors: Vidović A,Vilibić M,Sabioncello A,Gotovac K,Rabatić S,Folnegović-Šmalc V,Dekaris D

    更新日期:2009-06-01 00:00:00

  • Brain 5-HT function in bipolar affective disorder.

    abstract:BACKGROUND:Previous studies suggest that brain serotonin neurotransmission may mediate the actions of lithium carbonate. Acute tryptophan depletion (ATD) reduces brain serotonin and allows the study of this neurotransmitter in patient groups. Serotonin modulates electroencephalographic (EEG) activity, which is abnormal...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/S0924270800035481

    authors: Young AH,Hughes JH,Ashton CH

    更新日期:2000-09-01 00:00:00

  • Interferon, tryptophan and depression.

    abstract::Depression is a frequent comorbid disorder of many inflammatory diseases and it is suggested that brain inflammatory processes have a pathogenic role in mood dysregulation. Several immunocompromised patients have been treated with cytokines and long-term treatments have resulted in a variety of neuropsychiatric side-e...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1034/j.1601-5215.2003.00007.x

    authors: Fekkes D,Van Gool AR

    更新日期:2003-02-01 00:00:00

  • Electroconvulsive therapy versus transcranial magnetic stimulation for major depression: a review with recommendations for future research.

    abstract:OBJECTIVE:To review the literature comparing electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS) for major depression. METHODS:Data from the six randomised, prospective studies were agglutinated into one data set. Special attention was given to the methods of both TMS and ECT as well as data pe...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1111/j.1601-5215.2008.00333.x

    authors: Rasmussen KG

    更新日期:2008-12-01 00:00:00

  • Mediator effects of parameters of inflammation and neurogenesis from a N-acetyl cysteine clinical-trial for bipolar depression.

    abstract:OBJECTIVE:This study aimed to explore effects of adjunctive treatment with N-acetyl cysteine (NAC) on markers of inflammation and neurogenesis in bipolar depression. METHODS:This is a secondary analysis of a placebo-controlled randomised trial. Serum samples were collected at baseline, week 8, and week 32 of the open-...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章,随机对照试验

    doi:10.1017/neu.2018.13

    authors: Panizzutti B,Bortolasci C,Hasebe K,Kidnapillai S,Gray L,Walder K,Berk M,Mohebbi M,Dodd S,Gama C,Magalhães PV,Cotton SM,Kapczinski F,Bush AI,Malhi GS,Dean OM

    更新日期:2018-12-01 00:00:00

  • Integratie van opleiding en onderzoek in de opleiding tot psychiater.

    abstract::In the training program for residents in psychiatry, scientific education and participation in research projects are relatively underdeveloped. This may result in a gap between recently acquired scientific knowledge and its implementation in clinical practice. Since the start of the residency training in psychiatry in...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/S0924270800036310

    authors: Verhoeven WM,Goessens LF,van den Berg YW,Tuinier S

    更新日期:1999-03-01 00:00:00

  • Nitric oxide involvement in the antidepressant-like effect of ketamine in the Flinders sensitive line rat model of depression.

    abstract:OBJECTIVE:We investigated whether the nitric oxide (NO) precursor, L-arginine, can prevent the antidepressant-like action of the fast-acting antidepressant, ketamine, in a genetic rat model of depression, and/or induce changes in the glutamate (Glu)/N-methyl-D-aspartate receptor (NMDAR)/NO/cyclic guanosine monophosphat...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2014.39

    authors: Liebenberg N,Joca S,Wegener G

    更新日期:2015-04-01 00:00:00

  • Functional recovery results from the risperidone long-acting injectable versus quetiapine relapse prevention trial (ConstaTRE).

    abstract:OBJECTIVE:ConstaTRE is an open-label, randomised, controlled, relapse prevention trial in patients with stable schizophrenia or schizoaffective disorder switched to risperidone long-acting injectable (RLAI) or oral quetiapine, and was designed to test the hypothesis that injectable antipsychotic treatment with risperid...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2013.7

    authors: Rouillon F,Eriksson L,Burba B,Raboch J,Kaprinis G,Schreiner A

    更新日期:2013-10-01 00:00:00

  • Associations between C-reactive protein levels and cognition during the first 6 months after acute psychosis.

    abstract:OBJECTIVE:Inverse relationships between the C-reactive protein (CRP) levels and cognitive performance in acute psychosis have been demonstrated. We aimed to investigate how the serum level and initial change of CRP in acutely admitted patients with psychosis was correlated with cognitive performance during a 6-months f...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2018.25

    authors: Fathian F,Løberg EM,Gjestad R,Steen VM,Kroken RA,Jørgensen HA,Johnsen E

    更新日期:2019-02-01 00:00:00

  • Gene polymorphisms and response to transcranial direct current stimulation for auditory verbal hallucinations in schizophrenia.

    abstract:OBJECTIVE:Recent observations demonstrate a significant ameliorative effect of add-on transcranial direct current stimulation (tDCS) on auditory verbal hallucinations (AVHs) in schizophrenia. Of the many SNPs, NRG1 rs35753505 and catechol-o-methyl transferase (COMT) rs4680 polymorphisms have shown to have a strong asso...

    journal_title:Acta neuropsychiatrica

    pub_type: 杂志文章

    doi:10.1017/neu.2018.4

    authors: Chhabra H,Shivakumar V,Subbanna M,Kalmady SV,Bose A,Agarwal SM,Sreeraj VS,Dinakaran D,Narayanaswamy JC,Debnath M,Venkatasubramanian G

    更新日期:2018-08-01 00:00:00