Monoamines and CSF: relevance to neuropsychiatric disorders.

Abstract:

:Over the past 25 years much effort has been put into the research of the relationship between neuropsychiatric disorders and the concentrations of CSF-monoamine metabolites. Most of this research has beenfocused on the relation between CSF-concentrations of 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) and specific symptomatological entities, particularly schizophrenia, Alzheimer's dementia and endogenous depression. It appeared that specific relations between diseases and CSF-concentrations of monoamine metabolites cannot be longer maintained and that a more functional psychopathology should be considered as the future research strategy.

journal_name

Acta Neuropsychiatr

journal_title

Acta neuropsychiatrica

authors

Verhoeven WM

doi

10.1017/S0924270800034785

subject

Has Abstract

pub_date

1992-09-01 00:00:00

pages

47-51

issue

3

eissn

0924-2708

issn

1601-5215

pii

S0924270800034785

journal_volume

4

pub_type

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