Abstract:
INTRODUCTION AND AIM:Posttraumatic stress disorder (PTSD) is associated with increased medical morbidity, particularly from the autoimmune and cardiovascular diseases. Changes in the endocrine and immune system are key mediators in this process. The aim of our study was to investigate weather hormones (cortisol and prolactin), proinflammatory cytokines (interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α)), components of HPA-axis (lymphocyte expression of glucocorticoid receptor (GR)), immune function (natural killer cell cytotoxicity) and peripheral blood percentages of various lymphocyte subpopulations (T cells, helper T cells, cytotoxic T cells, B cells and natural killer cells) change in patients with posttraumatic stress disorder over time.
journal_name
Acta Neuropsychiatrjournal_title
Acta neuropsychiatricaauthors
Vidović A,Vilibić M,Sabioncello A,Gotovac K,Rabatić S,Folnegović-Šmalc V,Dekaris Ddoi
10.1017/S0924270800032725subject
Has Abstractpub_date
2009-06-01 00:00:00pages
46-50eissn
0924-2708issn
1601-5215pii
S0924270800032725journal_volume
21 Suppl 2pub_type
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