Lineage shift in Indian strains of Dengue virus serotype-3 (Genotype III), evidenced by detection of lineage IV strains in clinical cases from Kerala.

abstract：BACKGROUND:The Hepatitis B Virus X protein (HBx) plays a major role in hepatocellular carcinoma (HCC) development, however, its contribution to tumor invasion and metastasis has not been established so far. Heat shock protein 90 alpha (HSP90alpha) isoform is an ATP-dependent molecular chaperone that maintains the activ...

journal_title：Virology journal

authors： Li W,Miao X,Qi Z,Zeng W,Liang J,Liang Z

更新日期：2010-02-20 00:00:00

abstract：BACKGROUND:Multiple studies proved that miRNAs have a causal role in tumorigenesis. Some miRNAs are regulated by epigenetic alterations in their promoter regions and can be activated by chromatin- modifying drugs. METHODS:We treated cervical cancer cells with 5-aza-2'-deoxycytidine and get a microarray analysis. Dysre...

journal_title：Virology journal

authors： Yao T,Rao Q,Liu L,Zheng C,Xie Q,Liang J,Lin Z

更新日期：2013-06-03 00:00:00

abstract：BACKGROUND:Papillomaviruses (PVs) establish a persistent infection in the proliferating basal cells of the epithelium. The viral genome is replicated and maintained as a low-copy nuclear plasmid in basal keratinocytes. Bovine and human papillomaviruses (BPV and HPV) are known to utilize two viral proteins; E1, a DNA he...

journal_title：Virology journal

authors： Pittayakhajonwut D,Angeletti PC

更新日期：2010-06-10 00:00:00

abstract：:Modified vaccinia virus Ankara (MVA) has become a promising vaccine vector due to its immunogenicity and its proven safety in humans. As a general approach for stringent and rapid selection of recombinant MVA, we assessed marker rescue of the essential viral D4R gene in an engineered deletion mutant that is fully repl...

journal_title：Virology journal

authors： Ricci PS,Schäfer B,Kreil TR,Falkner FG,Holzer GW

更新日期：2011-12-12 00:00:00

abstract：:The TAR RNA of HIV was engineered as an siRNA delivery vehicle to develop a combinatorial therapeutic approach. The TAR backbone was found to be a versatile backbone for expressing siRNAs. Upon expression in human cells, pronounced and specific inhibition of reporter gene expression was observed with TARmiR. The resul...

journal_title：Virology journal

authors： Unwalla HJ,Rossi JJ

更新日期：2010-02-10 00:00:00

abstract：BACKGROUND:Newcastle Disease (ND) is a highly contagious and economically devastating disease of poultry. At present, limited molecular epidemiological data are available regarding the causes of ND outbreaks in vaccinated commercial poultry farms. Knowing the genomic characteristics of Newcastle disease virus (NDV) inf...

journal_title：Virology journal

authors： Umali DV,Ito H,Suzuki T,Shirota K,Katoh H,Ito T

更新日期：2013-11-09 00:00:00

abstract：BACKGROUND:There are over 100 known human adenovirus (HAdV) types, which are able to cause a broad variety of different self-limiting but also lethal diseases especially in immunocompromised patients. Only limited information about the pathogenesis and biology of the majority of these virus types is available. In the p...

journal_title：Virology journal

authors： Mese K,Bunz O,Schellhorn S,Volkwein W,Jung D,Gao J,Zhang W,Baiker A,Ehrhardt A

更新日期：2020-04-09 00:00:00

abstract：BACKGROUND:Patchouli alcohol (PA) is a tricyclic sesquiterpene extracted from Pogostemonis Herba, which is a traditional Chinese medicine used for therapy of inflammatory diseases. Recent studies have shown that PA has various pharmacological activities, including anti-bacterial and anti-viral effects. METHODS:In this...

journal_title：Virology journal

authors： Yu Y,Zhang Y,Wang S,Liu W,Hao C,Wang W

更新日期：2019-12-23 00:00:00

abstract：:Dengue virus (DENV) is a mosquito-borne virus that has four serotypes. Collection of serum from patients is time- and labor- consuming, and presents a high injury risk for infants and children. The genomic and serological diagnosis of imported dengue fever from a urine sample was used as a non-invasive diagnostic meth...

journal_title：Virology journal

authors： Ma X,Zhen W,Yang P,Sun X,Nie W,Zhang L,Xu H,Hu K

更新日期：2014-03-25 00:00:00

abstract：BACKGROUND:Previously, we have reported the isolation and molecular characterization of human Hepatitis C virus genotype 1 (HCV-1) from infected patients. We are now reporting an analysis of HCV obtained from patients infected with HCV genotype 3 (HCV-3) as diagnosed by clinical laboratories. RESULTS:HCV was cultured ...

journal_title：Virology journal

authors： Revie D,Alberti MO,Prichard JG,Kelley AS,Salahuddin SZ

更新日期：2010-07-13 00:00:00

abstract：:Measles, caused by measles virus (MeV), is a common infection in children. MeV is a member of the genus Morbillivirus and is most closely related to rinderpest virus (RPV), which is a pathogen of cattle. MeV is thought to have evolved in an environment where cattle and humans lived in close proximity. Understanding th...

journal_title：Virology journal

authors： Furuse Y,Suzuki A,Oshitani H

更新日期：2010-03-04 00:00:00

abstract：BACKGROUND:The amino terminus of the tobacco etch virus (TEV) capsid protein is located on the external surface of infectious TEV particles, as proposed by previous studies and an in silico model. The epsilon amino groups on the exposed lysine residues are available for chemical conjugation to any given protein, and ca...

journal_title：Virology journal

authors： Manuel-Cabrera CA,Márquez-Aguirre A,Rodolfo HG,Ortiz-Lazareno PC,Chavez-Calvillo G,Carrillo-Tripp M,Silva-Rosales L,Gutiérrez-Ortega A

更新日期：2012-03-27 00:00:00

abstract：BACKGROUND:Norovirus (NoV) has been recognized as the leading cause of both outbreaks and sporadic cases of acute gastroenteritis in children and adults worldwide. Stool samples collected from outpatients with clinical symptoms of acute gastroenteritis in all age groups at the First People's Hospital in Huzhou, Huzhou,...

journal_title：Virology journal

authors： Han J,Ji L,Shen Y,Wu X,Xu D,Chen L

更新日期：2015-09-11 00:00:00

abstract：BACKGROUND:Porcine circovirus type 2 (PCV2), the causative agent of postweaning multisystemic wasting syndrome (PMWS), is a serious economic problem in the swine industry. Different genotypes (PCV2a, PCV2b and PCV2d) of the virus are present in the clinical cases in China, and it is necessary to elucidate the pathogeni...

journal_title：Virology journal

authors： Guo LJ,Lu YH,Huang LP,Wei YW,Wu HL,Liu CM

更新日期：2011-06-10 00:00:00

abstract：BACKGROUND:Influenza A virus genomes are comprised of 8 negative strand single-stranded RNA segments and are thought to encode 11 proteins, which are all translated from mRNAs complementary to the genomic strands. Although human, swine and avian influenza A viruses are very similar, cross-species infections are usually...

journal_title：Virology journal

authors： Clifford M,Twigg J,Upton C

更新日期：2009-11-16 00:00:00

abstract：:RNA recombination is one of the two major factors that create RNA genome variability. Assessing its incidence in plant RNA viruses helps understand the formation of new isolates and evaluate the effectiveness of crop protection strategies. To search for recombination in Soybean mosaic virus (SMV), the causal agent of ...

journal_title：Virology journal

authors： Gagarinova AG,Babu M,Strömvik MV,Wang A

更新日期：2008-11-26 00:00:00

abstract：BACKGROUND:The genetic element s2m seems to represent one of very few examples of mobile genetic elements in viruses. The function remains obscure and a scattered taxonomical distribution has been reported by numerous groups. METHODS:We have searched GenBank in order to identify all viral accessions that have s2m(-lik...

journal_title：Virology journal

authors： Tengs T,Kristoffersen AB,Bachvaroff TR,Jonassen CM

更新日期：2013-04-25 00:00:00

abstract：BACKGROUND:Human cytomegalovirus (HCMV) is the most common cause of intrauterine infections worldwide. The toll-like receptors (TLRs) have been reported as important factors in immune response against HCMV. Particularly, TLR2, TLR4 and TLR9 have been shown to be involved in antiviral immunity. Evaluation of the role of...

journal_title：Virology journal

authors： Wujcicka W,Paradowska E,Studzińska M,Wilczyński J,Nowakowska D

更新日期：2017-03-24 00:00:00

abstract：BACKGROUND:Mumps virus is a negative-sense, single stranded RNA virus consisting of a ribonucleocapsid core enveloped by a lipid membrane derived from host cell, which causes mumps disease preventable by vaccination. Since virus lipid envelope and glycosylation pattern are not encoded by the virus but dependent on the ...

journal_title：Virology journal

authors： Brgles M,Bonta M,Šantak M,Jagušić M,Forčić D,Halassy B,Allmaier G,Marchetti-Deschmann M

更新日期：2016-01-14 00:00:00

abstract：BACKGROUND:The addition of N-linked glycans to proteins is normally a cotranslational process that occurs during translocation of the nascent protein to the endoplasmic reticulum. Here, we report on an exception to this rule occurring on the hepatitis B virus (HBV) large L envelope protein that is a subject to co-plus ...

journal_title：Virology journal

authors： Lambert C,Prange R

更新日期：2007-05-30 00:00:00

abstract：BACKGROUND:Cell culture adaptation of very virulent infectious bursal disease virus (vvIBDV) was shown to be mainly associated with the VP2 capsid protein residues 253, 279, and 284. The single mutation A284T proved critical for cell culture tropism, but did not confer efficient virus replication, which at least requir...

journal_title：Virology journal

authors： Ben Abdeljelil N,Khabouchi N,Kassar S,Miled K,Boubaker S,Ghram A,Mardassi H

更新日期：2014-11-25 00:00:00

abstract：BACKGROUND:Papillomaviruses (PVs) infecting artiodactyls are very diverse, and only second in number to PVs infecting primates. PVs associated to lesions in economically important ruminant species have been isolated from cattle and sheep. METHODS:Potential PV DNA from teat lesions of a Damascus goat was isolated, clon...

journal_title：Virology journal

authors： Willemsen A,van den Boom A,Dietz J,Bilge Dagalp S,Dogan F,Bravo IG,Ehrhardt A,Ehrke-Schulz E

更新日期：2020-10-30 00:00:00

abstract：BACKGROUND:ORFV attenuated live vaccines have been the main prophylactic measure against contagious ecthyma in sheep and goats in the last decades, which play an important role in preventing the outbreak of the disease. However, the available vaccines do not induce lasting immunity in sheep and goats. On the other hand...

journal_title：Virology journal

authors： Zhao K,He W,Gao W,Lu H,Han T,Li J,Zhang X,Zhang B,Wang G,Su G,Zhao Z,Song D,Gao F

更新日期：2011-12-29 00:00:00

abstract：BACKGROUND:The pattern recognition receptors (PPRs) are the earliest phase of the host defense against pathogens in genital epithelium, and toll-like receptors (TLRs) are best characterized PPRs mediating innate immune responses. Herpes simplex virus type 2 (HSV-2), a member of herpesviridae family, causes one of the m...

journal_title：Virology journal

authors： Lv X,Wang H,Su A,Xu S,Chu Y

更新日期：2018-11-12 00:00:00

abstract：BACKGROUND:Pseudorabies virus (PRV) of the family Herpesviridae is the causative agent of Aujeszky's disease. Attenuation of PRV by serial passaging in vitro is a well-established method; however, the dynamic variations occurring on viral genome during this process have not been characterized. METHODS:Genome sequencin...

journal_title：Virology journal

authors： Ye C,Wu J,Tong W,Shan T,Cheng X,Xu J,Liang C,Zheng H,Li G,Tong G

更新日期：2018-12-29 00:00:00

abstract：:Porcine Hokovirus (PHoV) was recently discovered in Hong Kong. This new Parvovirus of pigs is closely related to the human Parvoviruses 4 and 5 (PARV4/5) and bovine Hokovirus (BHoV). So far, nothing is known about the presence and prevalence of PHoV in regions of the world other than Hong Kong. A study was initiated t...

journal_title：Virology journal

authors： Adlhoch C,Kaiser M,Ellerbrok H,Pauli G

更新日期：2010-07-25 00:00:00

abstract：BACKGROUND:Norovirus is one of the most common causes of nonbacterial gastroenteritis in humans. Rapid spread by contaminated food and person-to-person transmission through the fecal-oral route are characteristics of norovirus epidemiology and result in high morbidity in vulnerable patient populations. Therefore, detec...

journal_title：Virology journal

authors： Lee SG,Lee SH,Park SW,Suh CI,Jheong WH,Oh S,Paik SY

更新日期：2011-05-26 00:00:00

abstract：:The prevalence of North American orthopoxviruses in nature is unknown and may be more difficult to ascertain due to wide spread use of vaccinia virus recombinant vaccines in the wild. A real time PCR assay was developed to allow for highly sensitive and specific detection of North American orthopoxvirus DNA in animal ...

journal_title：Virology journal

authors： Gallardo-Romero NF,Velasco-Villa A,Weiss SL,Emerson GL,Carroll DS,Hughes CM,Li Y,Karem KL,Damon IK,Olson VA

更新日期：2011-06-20 00:00:00

abstract：BACKGROUND:Torque Teno Virus (TTV) was the first single stranded circular DNA virus to be discovered that infects humans. Although there have been numerous reports regarding the prevalence of TTV from other countries of South Asia, there is severe lack of information regarding its prevalence in Pakistan. Thus the prese...

journal_title：Virology journal

authors： Hussain T,Manzoor S,Waheed Y,Tariq H,Hanif K

更新日期：2012-12-28 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV), human Rhinovirus (HRV) and human Metapneumo Virus (HMPV) are important viral pathogens causing acute respiratory tract infections in the hospitalized patients. Sensitive and accurate detection of RSV, HRV and HMPV is necessary for clinical diagnosis and treatment. RESULTS:...

journal_title：Virology journal

authors： Feng ZS,Zhao L,Wang J,Qiu FZ,Zhao MC,Wang L,Duan SX,Zhang RQ,Chen C,Qi JJ,Fan T,Li GX,Ma XJ

更新日期：2018-10-30 00:00:00