Abstract：
BACKGROUND:Little is known about HIV-1 subtype distribution in Morocco. Some data suggest an emergence of new HIV subtypes. We conducted phylogenetic analysis on a nationally representative sample of 60 HIV-1 viral specimens collected during 2004-2005 through the Morocco national HIV sentinel surveillance survey. RESULTS:While subtype B is still the most prevalent, 23.3% of samples represented non-B subtypes, the majority of which were classified as CRF02_AG (15%). Molecular clock analysis confirmed that the initial introduction of HIV-1B in Morocco probably came from Europe in the early 1980s. In contrast, the CRF02_AG strain appeared to be introduced from sub-Saharan Africa in two separate events in the 1990s. CONCLUSIONS:Subtype CRF02_AG has been emerging in Morocco since the 1990s. More information about the factors introducing HIV subtype-specific transmission will inform the prevention strategy in the region.
journal_name
AIDS Res Therjournal_title
AIDS research and therapyauthors
Akrim M,Lemrabet S,Elharti E,Gray RR,Tardy JC,Cook RL,Salemi M,Andre P,Azarian T,Aouad REdoi
10.1186/1742-6405-9-5subject
Has Abstractpub_date
2012-02-14 00:00:00pages
5issue
1issn
1742-6405pii
1742-6405-9-5journal_volume
9pub_type
杂志文章abstract：BACKGROUND:As a simplification strategy for treatment-experienced HIV-infected patients who have achieved virologic suppression on a multi-drug, multi-class antiretroviral regimen, the aim of this study was to evaluate the safety, efficacy, and pharmacokinetics of once-daily elvitegravir/cobicistat/emtricitabine/tenofo...
journal_title：AIDS research and therapy
pub_type： 临床试验,杂志文章
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更新日期：2017-11-02 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-2-1
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-5-2
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journal_title：AIDS research and therapy
pub_type： 杂志文章
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doi：10.1186/1742-6405-11-37
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pub_type： 杂志文章
doi：10.1186/1742-6405-9-14
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journal_title：AIDS research and therapy
pub_type： 杂志文章,评审
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journal_title：AIDS research and therapy
pub_type： 杂志文章,评审
doi：10.1186/s12981-017-0173-8
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-8-9
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-3-16
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journal_title：AIDS research and therapy
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doi：10.1186/s12981-018-0212-0
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journal_title：AIDS research and therapy
pub_type： 杂志文章,评审
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/s12981-017-0145-z
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journal_title：AIDS research and therapy
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doi：10.1186/s12981-019-0224-4
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journal_title：AIDS research and therapy
pub_type： 杂志文章
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pub_type： 杂志文章,评审
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journal_title：AIDS research and therapy
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journal_title：AIDS research and therapy
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journal_title：AIDS research and therapy
pub_type： 杂志文章
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/s12981-018-0190-2
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journal_title：AIDS research and therapy
pub_type： 杂志文章
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journal_title：AIDS research and therapy
pub_type： 杂志文章
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journal_title：AIDS research and therapy
pub_type： 杂志文章
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更新日期：2020-05-14 00:00:00
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journal_title：AIDS research and therapy
pub_type： 杂志文章
doi：10.1186/1742-6405-11-25
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