Ets family protein, erg expression in developing and adult mouse tissues by a highly specific monoclonal antibody.

abstract：:Minichromosome Maintenance (MCM) proteins play essential roles in various cancers. We previously reported that MCM7 could be a prognostic biomarker in non-small cell lung cancer (NSCLC). The purpose of current study is to explore roles of other MCM proteins in NSCLC and their correlation with clinico-pathologic parame...

journal_title：Journal of Cancer

authors： Liu YZ,Wang BS,Jiang YY,Cao J,Hao JJ,Zhang Y,Xu X,Cai Y,Wang MR

更新日期：2017-10-09 00:00:00

abstract：BACKGROUND:This study was performed to assess the impact of irradiation on the tissue penetration depth of doxorubicin delivered during Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC). METHODS:Fresh post mortem swine peritoneum was cut into 10 proportional sections. Except for 2 control samples, all received...

journal_title：Journal of Cancer

authors： Khosrawipour V,Giger-Pabst U,Khosrawipour T,Pour YH,Diaz-Carballo D,Förster E,Böse-Ribeiro H,Adamietz IA,Zieren J,Fakhrian K

更新日期：2016-05-07 00:00:00

abstract：:Levels of plasma cell-free DNA (cfDNA) of a large series of children with classical Hodgkin lymphoma (cHL) were evaluated and analyzed at diagnosis and during chemotherapy treatment in relation with clinical characteristics. CfDNA levels in cHL patients were significantly higher compared with controls (p=0.002). CfDNA...

journal_title：Journal of Cancer

authors： Primerano S,Burnelli R,Carraro E,Pillon M,Elia C,Farruggia P,Sala A,Vinti L,Buffardi S,Basso G,Mascarin M,Mussolin L

更新日期：2016-01-12 00:00:00

abstract：:There is limited literature documenting granulocytic sarcoma of the colon. We report a case of a 28 year-old female with a colonic granulocystic sarcoma of the colon as a complication of AML, as it is an important consideration with surgical management of typhilitis. ...

journal_title：Journal of Cancer

authors： Tsikitis VL,Corning C,Henderson J,Rose J

更新日期：2010-07-14 00:00:00

abstract：:Osteosarcoma (OS) is the most common primary bone malignancy, predominately affecting children and adolescents. Due to the introduction of chemotherapy, the 5-year survival rate of OS patients has dramatically improved to 60-70%. Unfortunately, OS patients with recurrence or metastatic disease have less than a 20% cha...

journal_title：Journal of Cancer

authors： Zhang Y,Zhao H,Xu W,Jiang D,Huang L,Li L

更新日期：2019-05-12 00:00:00

abstract：:The alterations of MET have been detected in non-small-cell lung cancer (NSCLC). However, the prognostic impact of MET gene copy number gain (CNG) has not been consistent among studies. We performed this meta-analysis to evaluate the prognostic value of high MET CNG in patients with NSCLC. A systematic computerized se...

journal_title：Journal of Cancer

authors： Kim JH,Kim HS,Kim BJ

更新日期：2018-04-23 00:00:00

abstract：:Peroxisome proliferator-activated receptor gamma (PPARγ), a member of the nuclear receptor superfamily, participates in multiple physiological and pathological processes. Extensive studies have revealed the relationship between PPARγ and various tumors. However, the expression and function of PPARγ in bladder cancer s...

journal_title：Journal of Cancer

authors： Peng T,Wang G,Cheng S,Xiong Y,Cao R,Qian K,Ju L,Wang X,Xiao Y

更新日期：2020-04-06 00:00:00

abstract：:Endometrial and ovarian cancers are two most common cancers affecting women in their post-menopausal years. To date, there are no simple biochemical tests to detect these cancers at early stages. Our previous study has demonstrated that the activity of total proprotein convertases (PCs) is significantly increased in u...

journal_title：Journal of Cancer

authors： Heng S,Stephens AN,Jobling TW,Nie G

更新日期：2016-08-12 00:00:00

abstract：:Background: Lysosome-associated protein transmembrane-4β-35(LAPTM4B-35) has been observed overexpressed in multiple malignant tumors. However, the prognostic value of LAPTM4B-35 remains controversial. Therefore, we conducted a meta-analysis to evaluate the prognostic value of LAPTM4B-35 in human cancers. Methods: The ...

journal_title：Journal of Cancer

authors： Zhou L,Dai C,Tian T,Wang M,Lin S,Deng Y,Xu P,Hao Q,Wu Y,Yang T,Zhu W,Dai Z

更新日期：2018-10-21 00:00:00

abstract：:Background: Esophageal squamous cell carcinoma (ESCC) has been having a high mortality rate in China. Most patients are diagnosed in advanced stages, leading to the poor prognosis and low 5-year survival rate. Detection of precancerous lesions or early cancers is the key to improving this situation. Although previous ...

journal_title：Journal of Cancer

authors： Sun Y,Zhang T,Wu W,Zhao D,Zhang N,Cui Y,Liu Y,Gu J,Lu P,Xue F,Yu J,Wang J

更新日期：2019-06-02 00:00:00

abstract：INTRODUCTION:Bioimpedance is a measure of the electrical properties of biological tissues. In the last two decades bioimpedance has been successfully introduced in clinical diagnosis of cancer. It has been demonstrated that tumoral tissues often show lower bioimpedance values than healthy tissues. The aim of this work ...

journal_title：Journal of Cancer

authors： Tatullo M,Marrelli M,Amantea M,Paduano F,Santacroce L,Gentile S,Scacco S

更新日期：2015-08-20 00:00:00

abstract：:Liver kinase B1 (LKB1) is a critical tumor suppressor that is frequently mutated in human cancers. LKB1 has serine/threonine protein kinase activity, which regulates gene expression by phosphorylation of Yes-Associated protein (YAP). The phosphorylation-dependent YAP shuttling is critically important intracellular mec...

journal_title：Journal of Cancer

authors： He L,Wu MZ,Wang XB,Qiu XS,Wang EH,Wu GP

更新日期：2019-06-09 00:00:00

abstract：:In this bi-institutional study, twenty-three stage IIIC-IV MAGE-A3(+) melanoma patients were vaccinated with M3TK-GML biweekly at three dose levels, with a subsequent phase of vaccinations at the maximum dose level. Anti-MAGE-A3 and anti-TK T cells were assessed by in vitro assay and delayed-type hypersensitivity skin...

journal_title：Journal of Cancer

authors： Russo V,Lunghi F,Fontana R,Bregni M

更新日期：2011-01-01 00:00:00

abstract：:Several randomized studies have been completed in prostate cancer that show a benefit to immediate postoperative treatment in patients undergoing prostatectomy. In one of the studies, there was even a survival advantage. In spite of those positive findings, there has been some reluctance to uniformly offer adjuvant tr...

journal_title：Journal of Cancer

authors： Swanson GP,Basler JW

更新日期：2010-12-07 00:00:00

abstract：:Increasing studies indicate that long noncoding RNA (lncRNA) plays a critical role in aerobic glycolysis of various tumors. However, the contribution of lncRNA in gastric cancer (GC) cell glycolysis is still poorly understood. The objective of this research was to investigate the functional role and mechanism of lncRN...

journal_title：Journal of Cancer

authors： Qian C,Xu Z,Chen L,Wang Y,Yao J

更新日期：2020-08-27 00:00:00

abstract：BACKGROUND AND AIMS:We compared clinicopathologic data and long-term clinical outcomes among patients with non-B and non-C hepatocellular carcinoma (NBNC-HCC) who underwent curative resection (group A, n=129), those with hepatitis B virus-related HCC (group B, n=62) and those with hepatitis C virus-related HCC (group C...

journal_title：Journal of Cancer

authors： Nishikawa H,Arimoto A,Wakasa T,Kita R,Kimura T,Osaki Y

更新日期：2013-07-18 00:00:00

abstract：:We found that microRNA-320a (miR-320a) was an attractive prognostic biomarker in breast cancer (BC) previously, whereas its regulatory mechanism in BC was not well understood. Our aim was to identify miR-320a target gene, examine the clinical relationship between miR-320a and its target, and further explore the functi...

journal_title：Journal of Cancer

authors： Yu J,Wang L,Yang H,Ding D,Zhang L,Wang J,Chen Q,Zou Q,Jin Y,Liu X

更新日期：2016-11-25 00:00:00

abstract：:EGFR mutation of Non-small cell lung cancers (NSCLC) was predominantly seen in Asian population and it was considered as a predictor of responsiveness. Eendothelial nitric oxide synthase (eNOS) plays a vital role in chronic inflammation and carcinogenesis. In this study, we aimed to explore the association between the...

journal_title：Journal of Cancer

authors： Huang CY,Hsieh MJ,Wu WJ,Chiang WL,Liu TC,Yang SF,Tsao TC

更新日期：2018-06-15 00:00:00

abstract：:Objectives: To investigate the role of inflammation-related factors, lymphocyte-to-monocyte ratio (LMR) alone and combined detection with cancer antigen 125 (CA125), in the prognostic assessment of ovarian cancer (OC). Methods: A retrospective clinicopathologic review was performed. The receiver-operating characterist...

journal_title：Journal of Cancer

authors： Tang Y,Hu HQ,Tang FX,Lin D,Shen R,Deng L,Tang YL,Deng LH,Zhou M,Li J,Su B,Xu F

更新日期：2020-03-04 00:00:00

abstract：:Objective: The applicability of the linear quadratic (LQ) model to local control (LC) modeling after hypofractionated radiotherapy to treat lung cancer is highly debated. To date, the differences in predicted outcomes between the LQ model and other radiobiological models, which are characterized by additional dose mod...

journal_title：Journal of Cancer

authors： Lu JY,Lin Z,Lin PX,Huang BT

更新日期：2019-08-08 00:00:00

abstract：:Mechanistic target of rapamycin (mTOR) plays a critical role in the development of oral squamous cell carcinoma (OSCC), but the underlying mechanisms remain poorly understood. Here we have demonstrated that the expression of osteopontin (OPN) was dramatically up-regulated in OSCC tissues and cell lines. Moreover, redu...

journal_title：Journal of Cancer

authors： Gan N,Zou S,Hang W,Yang D,Zhang X,Yin Y

更新日期：2017-05-12 00:00:00

abstract：:Purpose: To evaluate long-term survival trends after primary total laryngectomy (TL) for locally advanced laryngeal carcinoma (LC). Methods: A total of 2094 patients diagnosed with locally advanced LC and underwent primary TL (1992-2011, at least 5-year follow-up) in the Surveillance, Epidemiology, and End Results (SE...

journal_title：Journal of Cancer

authors： Lin Z,Lin H,Chen Y,Xu Y,Chen X,Fan H,Wu X,Ke X,Lin C

更新日期：2021-01-01 00:00:00

abstract：:As a crucial event involved in the metastasis and relapse of esophageal cancer, c-Met overexpression has been considered as one of the culprits responsible for the failure in patients who received radiochemotherapy. Since c-Met has been confirmed to be pivotal for cell survival, proliferation and migration, little is ...

journal_title：Journal of Cancer

authors： Chen GZ,Dai WS,Zhu HC,Song HM,Yang X,Wang YD,Min H,Lu Q,Liu S,Sun XC,Zeng XN

更新日期：2017-03-12 00:00:00

abstract：:Butyrate, a product of dietary fiber and a histone deacetylase inhibitor, induces apoptosis of colorectal cancer cells; this effect of butyrate is in part mediated by its ability to hyperactivate Wnt signaling, and may in part explain the preventive action of dietary fiber against colorectal cancer. However, the mecha...

journal_title：Journal of Cancer

authors： Bordonaro M

更新日期：2020-01-01 00:00:00

abstract：:RBP7 is a member of the cellular retinol-binding protein (CRBP) family and previous data suggested a link between CRBPs and the malignant transformation of colon cancer cells. Here, we investigated the potential of RBP7 as a predictive biomarker for patients with colon cancer and determined its functional relevance fo...

journal_title：Journal of Cancer

authors： Elmasry M,Brandl L,Engel J,Jung A,Kirchner T,Horst D

更新日期：2019-08-27 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide. However, science has not yet been able to substantially improve the prognosis of lung cancer patients. Accumulating evidence suggests that microRNAs (miRNAs) are key players in the regulation of tumor development and metastasis....

journal_title：Journal of Cancer

authors： Li Y,Zhang H,Dong Y,Fan Y,Li Y,Zhao C,Wang C,Liu J,Li X,Dong M,Liu H,Chen J

更新日期：2017-06-30 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the sixth most common tumor worldwide. The relationship between the gene methylation accumulation and HCC has been widely studied. In our study, we used the Sequenom EpiTYPER assay to investigate the methylation levels of the RASA3 in 164 HCC samples and paired adjacent non-cancerous ...

journal_title：Journal of Cancer

authors： Lin H,Fan X,He L,Zhou D

更新日期：2018-05-25 00:00:00

abstract：:Purpose: The aberrant of fibroblast growth factors and their receptors (FGF/FGFR) is an emerging target in the treatment of solid tumors. This study aimed to explore the landscape of FGF/FGFR alterations in a large cohort of cancer patients. Material and Methods: The formalin-fixed paraffin-embedded specimens of cance...

journal_title：Journal of Cancer

authors： Zuo W,He Y,Li W,Wu H,Zhao Z,Zhang Y,Chen S,Yin Y

更新日期：2020-09-23 00:00:00

abstract：OBJECTIVE:To elucidate the oncologic behavior of Micropapillary Urothelial Bladder Carcinoma (MPBC), a rare aggressive variant histology. METHODS:All MPBC patients in SEER 17 database were compared with those with traditional urothelial carcinoma (UC). Kaplan-Meier curves were used to determine OS and CSS. A Cox propo...

journal_title：Journal of Cancer

authors： Vourganti S,Harbin A,Singer EA,Shuch B,Metwalli AR,Agarwal PK

更新日期：2013-05-06 00:00:00

abstract：:Colorectal cancer (CRC) is the fifth leading cause of cancer-related death in China. The incidence of Chinese CRC has increased dramatically with the changes of dietary and lifestyle. However, the genetic landscape of Chinese colorectal cancer mutation is still poorly understood. In this study, we have performed whole...

journal_title：Journal of Cancer

authors： Ma R,Jing C,Zhang Y,Cao H,Liu S,Wang Z,Chen D,Zhang J,Wu Y,Wu J,Feng J

更新日期：2020-01-01 00:00:00