Comparison of clinical characteristics and survival after surgery in patients with non-B and non-C hepatocellular carcinoma and hepatitis virus-related hepatocellular carcinoma.

abstract：:Objective: Pancreatic cancer (PC) is a malignant tumor with limited therapeutic choices and extremely poor prognosis. Personalized therapy based on gene alternations is a promising choice. Considering tumor heterogeneity, the practice of ctDNA analysis has drawn the attention. Here, we try to assess the applicability ...

journal_title：Journal of Cancer

authors： Li H,Di Y,Li J,Jiang Y,He H,Yao L,Gu J,Lu J,Song J,Chen S,Cai S,Jin C,Yuan Z,Fu D

更新日期：2020-04-27 00:00:00

abstract：:We hypothesised that the blood levels of immune cells would be related to the progression of colorectal cancer and regional lymph node metastasis. We investigated the association between the blood levels of immune cells and regional lymph node metastasis in colorectal cancer patients. Patients with American Joint Comm...

journal_title：Journal of Cancer

authors： Lee JY,Seo EH,Oh CS,Paik JH,Hwang DY,Lee SH,Kim SH

更新日期：2017-05-10 00:00:00

abstract：:Objectives: Lung cancer in young adults is a distinct disease with particular socioeconomic implications. This study aimed to clarify the clinicopathological characteristics, best interventions, and outcomes of this distinctive entity. Methods: A retrospective review of patients with lung cancer was performed in our i...

journal_title：Journal of Cancer

authors： Liu B,Quan X,Xu C,Lv J,Li C,Dong L,Liu M

更新日期：2019-06-09 00:00:00

abstract：:Background: Heavy metal pollution in farm soils is a grave concern in Taiwan. Previously, we found the incidence of oral cancer (OC) correlated positively with levels of nickel and arsenic in farm soils. Many OC patients have a second malignancy, among which esophageal cancer (EC) is the most common one in Taiwan. Obj...

journal_title：Journal of Cancer

authors： Lee CP,Lee YH,Lian IB,Su CC

更新日期：2016-08-06 00:00:00

abstract：:Colorectal cancer (CRC) is considered to be closely associated with alteration of intestinal microorganisms. The purpose of present study was to investigate the distribution of gut microbiota in the distinction of microbiota dysbiosis between two disease syndromes called Zheng-Qi-Kui-Xu(ZQKX) and Xie-Du-Yong-Sheng (XD...

journal_title：Journal of Cancer

authors： Wang P,Ding S,Sun L,Feng Y,Guo K,Zhu Y,Huang D,Ruan S

更新日期：2020-10-23 00:00:00

abstract：:Alternative splicing plays critical roles in many disease processes and splicing dysregulation is a hallmark of cancer. The different splicing isoforms may have significantly different effects on the malignant progression of cancer. Checkpoint kinase 1 (CHK1) is a serine/threonine kinase and regulates DNA damage respo...

journal_title：Journal of Cancer

authors： Hu G,Wang S,Wang Y,Gao Y,Zhu H,Liu M,Xu N,Wang L

更新日期：2020-01-17 00:00:00

abstract：:Tissue-derived RNA, DNA and protein samples become more and more crucial for molecular detection in clinical research, personalized and targeted cancer therapy. This study evaluated how to biobanking colorectal tissues through examining the influences of cold ischemic time and freeze-thaw cycles on RNA, DNA and protei...

journal_title：Journal of Cancer

authors： Fan XJ,Huang Y,Wu PH,Yin XK,Yu XH,Fu XH,Feng LL,Wang YL,Yi HJ,Chen ZT,Yin JX,Zhang DL,Feng WX,Bai SM,Kim T,Mills GB,Lu YL,Wan XB,Wang L

更新日期：2019-08-27 00:00:00

abstract：:Lung cancer is the most common malignancy in China and is associated with a poor survival rate amongst Han Chinese. The high mortality is largely attributed to late-stage diagnosis, when treatment is largely ineffective. Identification of genetic variants could potentially assist with earlier diagnosis and thus more e...

journal_title：Journal of Cancer

authors： Hu W,Tang CH,Chen HT,Zhao J,Jin L,Kang L,Wu Y,Ying P,Wang CQ,Su CM

更新日期：2019-06-02 00:00:00

abstract：:Objectives: LncRNA associated with microvascular invasion in hepatocellular carcinoma (lncRNA MVIH) is a newly discovered long non-coding RNA that aberrantly up-regulates and holds prognostic value in various tumors. The aim of the review and meta-analysis is to assess its prognostic potential and functions in maligna...

journal_title：Journal of Cancer

authors： Zhang Y,Lin S,Yang X,Zhang X

更新日期：2019-02-26 00:00:00

abstract：:Purpose Neuroblastoma is an embryonic solid tumor derived from the progenitors of the sympathetic nervous system. More than half of the patients developed metastatic disease at the time of initial diagnosis and had poor outcome with current therapeutic approaches. In recent years, some obligate and facultative anaerob...

journal_title：Journal of Cancer

authors： Ning BT,Yu B,Chan S,Chan JL,Huang JD,Chan GC

更新日期：2017-06-03 00:00:00

abstract：:Apurinic/apyrimidinic endonuclease 1 (APE1) is an essential enzyme in the base excision repair pathway. Epidemiological studies have suggested associations between APE1 rs1760944 polymorphism and cancer risk. This study was aimed to evaluate the relationship between APE1 rs1760944 polymorphism and cancer risk. We sear...

journal_title：Journal of Cancer

authors： Dai ZJ,Wang XJ,Kang AJ,Ma XB,Min WL,Lin S,Zhao Y,Yang PT,Wang M,Kang HF

更新日期：2014-03-13 00:00:00

abstract：:Colorectal cancer (CRC) is an important health issue worldwide, accounting for the third place of cancer incidence. Chronic inflammation, as seen in Crohn's disease and ulcerative colitis, is the most important risk factor for developing CRC, as it favours neoplastic transformation by enhancing epithelial cell turnove...

journal_title：Journal of Cancer

authors： Figueroa-González G,García-Castillo V,Coronel-Hernández J,López-Urrutia E,León-Cabrera S,Arias-Romero LE,Terrazas LI,Rodríguez-Sosa M,Campos-Parra AD,Zúñiga-Calzada E,Lopez-Camarillo C,Morales-González F,Jacobo-Herrera NJ,Pérez

更新日期：2016-07-25 00:00:00

abstract：:Background: To develop and validate a radiomic nomogram incorporating radiomic features with clinical variables for individual local recurrence risk assessment in nasopharyngeal carcinoma (NPC) patients before initial treatment. Methods: One hundred and forty patients were randomly divided into a training cohort (n = ...

journal_title：Journal of Cancer

authors： Zhang L,Zhou H,Gu D,Tian J,Zhang B,Dong D,Mo X,Liu J,Luo X,Pei S,Dong Y,Huang W,Chen Q,Liang C,Lian Z,Zhang S

更新日期：2019-07-10 00:00:00

abstract：:Objective: The applicability of the linear quadratic (LQ) model to local control (LC) modeling after hypofractionated radiotherapy to treat lung cancer is highly debated. To date, the differences in predicted outcomes between the LQ model and other radiobiological models, which are characterized by additional dose mod...

journal_title：Journal of Cancer

authors： Lu JY,Lin Z,Lin PX,Huang BT

更新日期：2019-08-08 00:00:00

abstract：:Non epithelial ovarian tumors represent a small group of rare gynecological cancers but they have a high incidence in young childbearing women. The recent years fertility preservation surgeries have become a common practice in specific ovarian malignancies when the patients wish to maintain their fertility. Specific t...

journal_title：Journal of Cancer

authors： Thomakos N,Malakasis A,Machairiotis N,Zarogoulidis P,Rodolakis A

更新日期：2018-11-24 00:00:00

abstract：:Melanoma is the most aggressive and treatment-resistant form of skin cancer. Curcumol is a Chinese medicinal herb traditionally used as a cancer remedy. However, the molecular mechanisms underlying the anticancer activity of curcumol in melanoma remains largely unknown. In the present study, we observed that Curcumol ...

journal_title：Journal of Cancer

authors： Ning N,Liu S,Liu X,Tian Z,Jiang Y,Yu N,Tan B,Feng H,Feng X,Zou L

更新日期：2020-01-14 00:00:00

abstract：BACKGROUND:We conducted this pooled analysis to investigate the impact of RECIST 1.1 on the selection of target lesions and classification of tumor response, in comparison with RECIST 1.0. Methods : We searched MEDLINE and EMBASE for articles with terms of RECIST 1.0 or RECIST 1.1. We looked into all abstracts and virt...

journal_title：Journal of Cancer

authors： Kim JH,Min SJ,Jang HJ,Cho JW,Kim SH,Kim HS

更新日期：2015-02-25 00:00:00

abstract：:Establishing an applicable preclinical model is vital for translational cancer research. Patient-derived xenograft has been important preclinical model systems and widely used for cancer research. Patient-derived xenograft models that represent the tumors of the patients are necessary to better translate research disc...

journal_title：Journal of Cancer

authors： Chen C,Lin W,Huang Y,Chen X,Wang H,Teng L

更新日期：2021-01-01 00:00:00

abstract：:Background: Surgery for pancreatic cancer with liver metastases (PCL) is not recommended in the international guidelines, and investigation of its clinical significance in patients with PCL is very limited. This study explored whether surgery, especially synchronous resection of the primary tumor and liver metastases ...

journal_title：Journal of Cancer

authors： Su BB,Bai DS,Yu JQ,Zhang C,Jin SJ,Zhou BH,Jiang GQ

更新日期：2021-01-01 00:00:00

abstract：:Tyrosine phosphorylation is an important post-translation modification of proteins that is controlled by tyrosine kinases and phosphatases. Disruption of the balance between the activity of tyrosine kinases and phosphatases may result in diseases. Receptor type protein tyrosine phosphatase epsilon (PTPRE) is closely r...

journal_title：Journal of Cancer

authors： Liang J,Shi J,Wang N,Zhao H,Sun J

更新日期：2019-01-01 00:00:00

abstract：:Objective: Multiple reports have described the proportion of T-regulatory cells (Tregs) in peripheral blood (PB) and tissues in patients with gynecological cancers (GCs) with controversial results. Thus, the aim of this study was to investigate the proportion of Tregs and its prognostic survival role in GCs patients. ...

journal_title：Journal of Cancer

authors： Hu J,Wu X,Huang P,Teng F,Wang Y,Xue F

更新日期：2020-03-05 00:00:00

abstract：:Our previous studies have demonstrated that the compound fuling granule (CFG), a traditional Chinese medicine, suppresses ovarian cancer cell growth, migration and metastasis. However, the underlying mechanisms remain to be fully elucidated. In this study, we found that CFG could induce mitochondrial fragmentation, mi...

journal_title：Journal of Cancer

authors： Ruan S,Zhang Z,Tian X,Huang D,Liu W,Yang B,Shen M,Tao F

更新日期：2018-09-08 00:00:00

abstract：BACKGROUND:The 2010 guidelines by ASCO-CAP have mandated that breast cancer specimens with ≥1% positively staining cells by immunohistochemistry should be considered Estrogen Receptor (ER) positive. This has led to a subclass of low-ER positive (1-10%) breast cancers. We have examined the biology and clinical behavior ...

journal_title：Journal of Cancer

authors： Prabhu JS,Korlimarla A,Desai K,Alexander A,Raghavan R,Anupama C,Dendukuri N,Manjunath S,Correa M,Raman N,Kalamdani A,Prasad M,Gopinath KS,Srinath BS,Sridhar TS

更新日期：2014-01-23 00:00:00

abstract：:Objective: This study aimed to evaluate the therapeutic response of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) with diffusion kurtosis imaging (DKI). Methods: Forty-three patients with fifty-nine hepatic cancer nodules were recruited for this study. All patients were treated b...

journal_title：Journal of Cancer

authors： Yuan ZG,Wang ZY,Xia MY,Li FZ,Li Y,Shen Z,Wang XZ

更新日期：2020-02-10 00:00:00

abstract：:The 21-gene recurrence score (RS) is increasingly being used for patients with early stage, hormone receptor-positive, Her-2-negative breast cancer. However, these results are largely from populations with infiltrating ductal carcinoma (IDC). The clinical value of RS testing in mucinous carcinoma has not been well inv...

journal_title：Journal of Cancer

authors： Wang W,Chen X,Lin L,Fei X,Garfield DH,Hong J,Gao W,Zhu S,Wu J,Huang O,He J,Li Y,Zhu L,Chen W,Shen K

更新日期：2018-08-06 00:00:00

abstract：:Objectives: For patients with multiple small-sized pulmonary cancers, a lobectomy can disrupt future therapeutic options for other lesions. It was recently reported that limited pulmonary resections were not inferior to lobectomy for the management of selected peripheral small-sized pulmonary adenocarcinomas. Patients...

journal_title：Journal of Cancer

authors： Nakagiri T,Nakayama T,Tokunaga T,Takenaka A,Kunoh H,Ishida H,Tomita Y,Nakatsuka SI,Nakamura H,Okami J,Higashiyama M

更新日期：2020-02-20 00:00:00

abstract：:Purpose: Systemic therapy has often been used for patients with advanced hepatocellular carcinoma (HCC). However, due to drug resistance, the use of cytotoxic chemotherapy in the treatment of patients with advanced HCC has typically demonstrated low response rates. Secretory clusterin (sCLU) is expressed in aggressive...

journal_title：Journal of Cancer

authors： Wang X,Zou F,Zhong J,Yue L,Wang F,Wei H,Yang G,Jin T,Dong X,Li J,Xiu P

更新日期：2018-04-06 00:00:00

abstract：:Osteosarcoma (OS) is the most common primary bone malignancy, predominately affecting children and adolescents. Due to the introduction of chemotherapy, the 5-year survival rate of OS patients has dramatically improved to 60-70%. Unfortunately, OS patients with recurrence or metastatic disease have less than a 20% cha...

journal_title：Journal of Cancer

authors： Zhang Y,Zhao H,Xu W,Jiang D,Huang L,Li L

更新日期：2019-05-12 00:00:00

abstract：:Cancer cells express epithelial markers, and when progressing in malignancy they may express markers of the mesenchymal cell type. Therefore an epithelial-mesenchymal transition of the cancer cells is assumed. However the mesenchymal markers can equally well be interpreted as myeloid markers since they are common in b...

journal_title：Journal of Cancer

authors： Schramm HM

更新日期：2014-01-15 00:00:00

abstract：:Background: To identify associated risk factors and develop a predictive nomogram for the early death of metastatic gastric cancer patients. Methods: A total of 4575 patients in the SEER cohort and 220 patients in the Chinese cohort diagnosed with metastatic gastric cancer in our Cancer Center were obtained. Univariat...

journal_title：Journal of Cancer

authors： Zhu Y,Fang X,Wang L,Zhang T,Yu D

更新日期：2020-07-14 00:00:00