Effect of Irradiation on Tissue Penetration Depth of Doxorubicin after Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC) in a Novel Ex-Vivo Model.

abstract：PURPOSE:The current study examined quality of life, progression of disease, and survival rate during chemotherapy in newly diagnosed non-small cell lung cancer (NSCLC) patients with depression (n=48) and without depression (n=78). Further, the study explored the hypothesis that the survival benefit resulted from the ch...

journal_title：Journal of Cancer

authors： Chen J,Li W,Cui L,Qian Y,Zhu Y,Gu H,Chen G,Shen Y,Liu Y

更新日期：2015-09-15 00:00:00

abstract：:Non epithelial ovarian tumors represent a small group of rare gynecological cancers but they have a high incidence in young childbearing women. The recent years fertility preservation surgeries have become a common practice in specific ovarian malignancies when the patients wish to maintain their fertility. Specific t...

journal_title：Journal of Cancer

authors： Thomakos N,Malakasis A,Machairiotis N,Zarogoulidis P,Rodolakis A

更新日期：2018-11-24 00:00:00

abstract：:Ovarian cancer is a highly lethal malignancy in the female reproductive system. Platinum drugs, represented by cisplatin, are the first-line chemotherapeutic agents for treatment of various malignancies including ovarian cancer, but drug resistance leads to chemotherapy failure. MicroRNAs emerged as promising molecule...

journal_title：Journal of Cancer

authors： Xiang Y,Chen YJ,Yan YB,Liu Y,Qiu J,Tan RQ,Tian Q,Guan L,Niu SS,Xin HW

更新日期：2020-03-13 00:00:00

abstract：:Mechanistic target of rapamycin (mTOR) plays a critical role in the development of oral squamous cell carcinoma (OSCC), but the underlying mechanisms remain poorly understood. Here we have demonstrated that the expression of osteopontin (OPN) was dramatically up-regulated in OSCC tissues and cell lines. Moreover, redu...

journal_title：Journal of Cancer

authors： Gan N,Zou S,Hang W,Yang D,Zhang X,Yin Y

更新日期：2017-05-12 00:00:00

abstract：:Purpose: To evaluate the detection of gene mutations in bone marrow biopsy and circulating free DNA (cfDNA) from plasma in multiple myeloma (MM). Experimental design: We used cell-free DNA from plasma and bone marrow to test BRAF V600, KRAS G12/G13, NRAS G12/G13 and NRAS Q61 mutations using multiplex assays for drople...

journal_title：Journal of Cancer

authors： Li Q,Huang HJ,Ma J,Wang Y,Cao Z,Karlin-Neumann G,Janku F,Liu Z

更新日期：2020-03-15 00:00:00

abstract：:Purpose: We retrospectively collected consecutive survival data of lung adenosquamous cell carcinoma (ASC) patients with brain metastasis (BM) in our institute and discussed the factors related to prognosis of these patients. Patients and Methods: A total of 42 patients diagnosed as lung ASC with BM between July 1, 20...

journal_title：Journal of Cancer

authors： Pan F,Cui S,Wang W,Gu A,Jiang L

更新日期：2018-09-08 00:00:00

abstract：:Background: The purpose of this study was to examine and compare the prognostic value of different immunization-based scoring systems in patients with soft tissue sarcoma (STS). Methods: We conducted a retrospective study evaluating a cohort of 165 patients diagnosed with STS between July 2007 and July 2014. The relat...

journal_title：Journal of Cancer

authors： Jiang SS,Jiang L,Weng DS,Li YF,Pan QZ,Zhao JJ,Tang Y,Zhou ZW,Xia JC

更新日期：2017-02-25 00:00:00

abstract：PURPOSE:We conducted a meta-analysis to evaluate and compare the short- and long-term results of laparoscopy-assisted colectomy (LAC) and open colectomy (OC) for colon cancer. METHODS:We searched MEDLINE, EMBASE, Science Citation Index, and Cochrane Controlled Trial Register for relevant papers published between Janua...

journal_title：Journal of Cancer

authors： Ohtani H,Tamamori Y,Arimoto Y,Nishiguchi Y,Maeda K,Hirakawa K

更新日期：2012-01-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) is currently one of the most intractable malignancies with a typical scirrhous pattern in histology. Due to its abundant tumor stroma and scant vascularization, chemotherapeutic agents are considered inefficiently permeable to cancer nests, making it highly difficult to cure the...

journal_title：Journal of Cancer

authors： Saito K,Sakaguchi M,Maruyama S,Iioka H,Putranto EW,Sumardika IW,Tomonobu N,Kawasaki T,Homma K,Kondo E

更新日期：2018-07-30 00:00:00

abstract：BACKGROUND:Medullary thyroid cancer (MTC) commonly presents with lymph node (LN) metastases, and has a worse prognosis than papillary thyroid cancer (PTC). Tumor size and LN involvement have been shown to affect stage of disease; however, to our knowledge, ours is the first study that attempts to correlate anterior nec...

journal_title：Journal of Cancer

authors： Guerrero MA,Lindsay S,Suh I,Vriens MR,Khanafshar E,Shen WT,Gosnell J,Kebebew E,Duh QY,Clark OH

更新日期：2011-04-08 00:00:00

abstract：:Purpose: MicroRNAs (miRNAs) are key regulators of the growth and development of a wide range of cancer types such as colorectal cancer (CRC). A number of previously studies have observed that the levels of miR-365a-3p expression are dysregulated in many cancers, but the specific role of this miRNA in CRC and its assoc...

journal_title：Journal of Cancer

authors： Hong YG,Xin C,Zheng H,Huang ZP,Yang Y,Zhou JD,Gao XH,Hao L,Liu QZ,Zhang W,Hao LQ

更新日期：2020-03-26 00:00:00

abstract：:Colorectal cancer (CRC) is the fifth leading cause of cancer-related death in China. The incidence of Chinese CRC has increased dramatically with the changes of dietary and lifestyle. However, the genetic landscape of Chinese colorectal cancer mutation is still poorly understood. In this study, we have performed whole...

journal_title：Journal of Cancer

authors： Ma R,Jing C,Zhang Y,Cao H,Liu S,Wang Z,Chen D,Zhang J,Wu Y,Wu J,Feng J

更新日期：2020-01-01 00:00:00

abstract：:Background: The Aldehyde dehydrogenase 2 (ALDH2) mutant genotypes contain an allele encoding defective ALDH2 with reduced efficacy of alcohol metabolism leading to accumulation of highly toxic and carcinogenic acetaldehyde. It can induce unpleasant "Asian flush syndrome" and associate with increased risk of cancers. H...

journal_title：Journal of Cancer

authors： Huang PH,Hu CC,Chien CH,Chen LW,Chien RN,Lin YS,Chao M,Lin CL,Yeh CT

更新日期：2019-10-03 00:00:00

abstract：:Background: This study aimed to clarify the impact of node involvement (affected to resected nodes) in optimally cytoreduced (residual tumour ≤1cm) stage IIIC/IV ovarian cancer. Methods: 108 consecutive patients with primary stage IIIC/IV ovarian cancer underwent stage-related surgery and got adjuvant platinum-based c...

journal_title：Journal of Cancer

authors： Bachmann C,Bachmann R,Fend F,Wallwiener D

更新日期：2016-11-09 00:00:00

abstract：:Myeloid-derived suppressor cells (MDSCs) have strong immunosuppressive functions and contribute to the formation of the tumor microenvironment. Long non-coding (Lnc) RNAs are highly important factors associated with tumors and may be used as markers for tumor diagnosis, which is valuable for targeted therapy. LncRNA M...

journal_title：Journal of Cancer

authors： Zhou Q,Tang X,Tian X,Tian J,Zhang Y,Ma J,Xu H,Wang S

更新日期：2018-06-14 00:00:00

abstract：UNLABELLED:The mechanism of progression from ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) remains largely unknown. We compared gene expression in tumors with simultaneous DCIS and IDC to decipher how diverse proteins participate in the local invasive process.Twenty frozen tumor specimens with conc...

journal_title：Journal of Cancer

authors： Castellana B,Escuin D,Peiró G,Garcia-Valdecasas B,Vázquez T,Pons C,Pérez-Olabarria M,Barnadas A,Lerma E

更新日期：2012-01-01 00:00:00

abstract：:Background: The transfusion of blood that has been stored for some time was found to be associated with transfusion-related immune modulation (TRIM) responses in cancer patients, which could result in poor clinical outcomes, such as tumor recurrence, metastasis and reduced survival rate. Given the prior observation of...

journal_title：Journal of Cancer

authors： Zhang J,Chen S,Yan Y,Zhu X,Qi Q,Zhang Y,Zhang Q,Xia R

更新日期：2019-06-02 00:00:00

abstract：:Neural invasion (NI) is one of the important routes for local spread of gastric cancer (GC) correlated with poor prognosis. However, the exact cellular characteristics and molecular mechanisms of NI in GC are still unclear. Netrin-1(NTN1) as an axon guidance molecule was firstly found during neural system development....

journal_title：Journal of Cancer

authors： Yin K,Wang L,Xia Y,Dang S,Zhang X,He Z,Xu J,Shang M,Xu Z

更新日期：2019-06-02 00:00:00

abstract：BACKGROUND:Age-adjusted evaluations have explored the possible utility of (HPV test results in women with LSIL Pap. We investigated HPV test results and histopathologic follow-up results of LSIL patients from China's largest CAP-certified laboratory. METHODS:Patients with LSIL between 2011 and 2015 from the Guangzhou ...

journal_title：Journal of Cancer

authors： Zheng B,Yang H,Li Z,Wei G,You J,Liang X,Zhao C

更新日期：2017-07-23 00:00:00

abstract：:Background: Sorafenib has been recommended as the standard therapy for advanced HCC with extrahepatic metastasis. The purpose of this retrospective study was to investigate the difference in overall survival (OS) between treatments with sorafenib combined with regional therapies versus sorafenib monotherapy in hepatoc...

journal_title：Journal of Cancer

authors： Chen J,Lu S,Zhang Y,Xu L,Chen J,Wang J,Chen M,Zhang R,Zhou Z

更新日期：2018-04-19 00:00:00

abstract：:Objective: The applicability of the linear quadratic (LQ) model to local control (LC) modeling after hypofractionated radiotherapy to treat lung cancer is highly debated. To date, the differences in predicted outcomes between the LQ model and other radiobiological models, which are characterized by additional dose mod...

journal_title：Journal of Cancer

authors： Lu JY,Lin Z,Lin PX,Huang BT

更新日期：2019-08-08 00:00:00

abstract：:In this article, the use of different types of thermotherapies to treat breast cancer is reviewed. While hyperthermia is most commonly used as an adjuvant in combination with radiotherapy, chemotherapy, targeted therapy or cryotherapy to enhance the therapeutic effect of these therapies, thermoablation is usually carr...

journal_title：Journal of Cancer

authors： Alphandéry E

更新日期：2014-05-29 00:00:00

abstract：:Objectives: For patients with multiple small-sized pulmonary cancers, a lobectomy can disrupt future therapeutic options for other lesions. It was recently reported that limited pulmonary resections were not inferior to lobectomy for the management of selected peripheral small-sized pulmonary adenocarcinomas. Patients...

journal_title：Journal of Cancer

authors： Nakagiri T,Nakayama T,Tokunaga T,Takenaka A,Kunoh H,Ishida H,Tomita Y,Nakatsuka SI,Nakamura H,Okami J,Higashiyama M

更新日期：2020-02-20 00:00:00

abstract：:Background: Esophageal squamous cell carcinoma (ESCC) has been having a high mortality rate in China. Most patients are diagnosed in advanced stages, leading to the poor prognosis and low 5-year survival rate. Detection of precancerous lesions or early cancers is the key to improving this situation. Although previous ...

journal_title：Journal of Cancer

authors： Sun Y,Zhang T,Wu W,Zhao D,Zhang N,Cui Y,Liu Y,Gu J,Lu P,Xue F,Yu J,Wang J

更新日期：2019-06-02 00:00:00

abstract：:Oncogenic activation of the ETS Related Gene (ERG) in humans was originally identified in subsets of Ewing sarcomas, myeloid leukemias and, recently, in the majority of prostate cancers. Expression of human ERG protein and consequently its functions in normal and disease states needs to be better understood in light o...

journal_title：Journal of Cancer

authors： Mohamed AA,Tan SH,Mikhalkevich N,Ponniah S,Vasioukhin V,Bieberich CJ,Sesterhenn IA,Dobi A,Srivastava S,Sreenath TL

更新日期：2010-10-25 00:00:00

abstract：:Introduction: Preoperative risk stratification is crucial for clinical treatment of endometrial cancer (EC). This study aimed to establish a model based on magnetic resonance imaging (MRI) and clinical factors for risk classification of EC. Materials and Methods: A total of 102 patients with pathologically proven Stag...

journal_title：Journal of Cancer

authors： Chen J,Gu H,Fan W,Wang Y,Chen S,Chen X,Wang Z

更新日期：2021-01-01 00:00:00

abstract：:Background: miRNAs dysregulate in hepatocellular carcinoma (HCC), showing promise for diagnostic biomarkers which may be found through exploration of differentially expressed miRNAs when comparing HCC and normal liver tissues. Materials and Methods: In the present research, candidate miRNAs were selected and verified ...

journal_title：Journal of Cancer

authors： Ji J,Chen H,Liu XP,Wang YH,Luo CL,Zhang WW,Xie W,Wang FB

更新日期：2018-09-08 00:00:00

abstract：OBJECTIVE(S):To assess skeletal wide fracture location and time of fracture after cancer treatment Study Design: One hundred thirty-nine women diagnosed with breast or gynecologic cancer between 2003 and 2012 that subsequently had a radiologic diagnosis of fracture were identified retrospectively using electronic medic...

journal_title：Journal of Cancer

authors： Hui SK,Arentsen L,Wilcox A,Shanley R,Yee D,Ghebre R

更新日期：2015-01-01 00:00:00

abstract：:Tumor growth depends on angiogenesis, the growth of new blood vessels. Complement factor H (CFH) is a plasma glycoprotein that functions as a regulator of the complement system. The aim of this study is to delineate the role of CFH in angiogenesis. A conditional null allele of the Cfh gene was generated in C57BL/6J mi...

journal_title：Journal of Cancer

authors： Liu J,Hoh J

更新日期：2017-07-15 00:00:00

abstract：:Breast cancer is considered as a heterogeneous disease comprising various types of neoplasms, which involves different profile changes in both mRNA and micro-RNA (miRNA) expression. Extensive studies on mRNA expression in breast tumor have yielded some very interesting findings, some of which have been validated and u...

journal_title：Journal of Cancer

authors： Fu SW,Chen L,Man YG

更新日期：2011-02-24 00:00:00