Delayed extensive brain edema caused by the growth of a giant basilar apex aneurysm treated with basilar artery obliteration: a case report.

abstract：BACKGROUND:Road traffic accidents are known to be the main cause of traumatic brain injury (TBI). TBI is also a leading cause of death and disability. This study, by means of the idiographic approach (single-case experimental designs using multiple-baseline designs), has examined whether methylphenidate (MPH - trade na...

journal_title：BMC neurology

authors： Al-Adawi S,Al-Naamani A,Jaju S,Al-Farsi YM,Dorvlo ASS,Al-Maashani A,Al-Adawi SSH,Moustafa AA,Al-Sibani N,Essa MM,Burke DT,Qoronfleh MW

更新日期：2020-03-19 00:00:00

abstract：BACKGROUND:Facioscapulohumeral muscular dystrophy (FSHD) is a dominantly-inherited progressive muscular dystrophy caused by de-repression of the DUX4 gene, which causes disease by a toxic-gain-of-function. As molecularly targeted drugs move from preclinical testing into human trials, it is essential that we validate cl...

journal_title：BMC neurology

authors： LoRusso S,Johnson NE,McDermott MP,Eichinger K,Butterfield RJ,Carraro E,Higgs K,Lewis L,Mul K,Sacconi S,Sansone VA,Shieh P,van Engelen B,Wagner K,Wang L,Statland JM,Tawil R,ReSolve Investigators and the FSHD CTRN18.

更新日期：2019-09-10 00:00:00

abstract：BACKGROUND:THK5351 and flortaucipir tau ligands have high affinity for paired helical filament tau, yet diverse off-target bindings have been reported. Recent data support the hypothesis that THK5351 binds to monoamine oxidase B (MAO-B) expressed from reactive astrocytes and that flortaucipir has an affinity toward MAO...

journal_title：BMC neurology

authors： Kim HJ,Cho H,Park S,Jang H,Ryu YH,Choi JY,Moon SH,Oh SJ,Oh M,Na DL,Lyoo CH,Kim EJ,Seeley WW,Kim JS,Choi KC,Seo SW

更新日期：2019-08-29 00:00:00

abstract：BACKGROUND:Past studies found that cerebral developmental venous anomaly (DVA) is often concurrent with cavernous malformation (CM). But the reason of the concurrency remains unknown. The purpose of this study was to confirm whether angioarchitectural factors relate to the concurrence and which angioarchitectural facto...

journal_title：BMC neurology

authors： Yu T,Liu X,Lin X,Bai C,Zhao J,Zhang J,Zhang L,Wu Z,Wang S,Zhao Y,Meng G

更新日期：2016-09-22 00:00:00

abstract：BACKGROUND:Chronic headache (headache ≥ 15 days/month for at least 3 months) affects 2-5% of the general population. Medication overuse contributes to the problem. Medication-overuse headache (MOH) can be identified by using the Severity of Dependence Scale (SDS). A "brief intervention" scheme (BI) has previously been ...

journal_title：BMC neurology

authors： Kristoffersen ES,Straand J,Benth JS,Russell MB,Lundqvist C

更新日期：2012-08-10 00:00:00

abstract：BACKGROUND:Friedreich ataxia is a neurological disease originating from an iron-sulfur cluster enzyme deficiency due to impaired iron handling in the mitochondrion, aconitase being particularly affected. As a mean to counteract disease progression, it has been suggested to chelate free mitochondrial iron. Recent years ...

journal_title：BMC neurology

authors： Goncalves S,Paupe V,Dassa EP,Rustin P

更新日期：2008-06-16 00:00:00

abstract：BACKGROUND:Assessing primary rehabilitation needs in patients with acquired brain injury is a challenge due to case complexity and the heterogeneity of symptoms after brain injury. The Rehabilitation Complexity Scale-Extended (RCS-E) is an instrument used in assessment of rehabilitation complexity in patients with seve...

journal_title：BMC neurology

authors： Maribo T,Pedersen AR,Jensen J,Nielsen JF

更新日期：2016-10-21 00:00:00

abstract：BACKGROUND:The evidence base for the effectiveness of psychological interventions for patients with dissociative non-epileptic seizures (DS) is currently extremely limited, although data from two small pilot randomised controlled trials (RCTs), including from our group, suggest that Cognitive Behavioural Therapy (CBT) ...

journal_title：BMC neurology

authors： Goldstein LH,Mellers JD,Landau S,Stone J,Carson A,Medford N,Reuber M,Richardson M,McCrone P,Murray J,Chalder T

更新日期：2015-06-27 00:00:00

abstract：BACKGROUND:Inflammatory reactions occurring in the brain after ischemia may contribute to secondary damage. In the present study, effects of minocycline, an anti-inflammatory agent, alone or in combination with mild hypothermia on focal embolic cerebral ischemia have been examined. METHODS:Focal ischemic injury was in...

journal_title：BMC neurology

authors： Wang CX,Yang T,Noor R,Shuaib A

更新日期：2002-04-18 00:00:00

abstract：ASBTRACT:BACKGROUND: There are limited neuroprotective treatment options for patients with aneurysmal subarachnoid hemorrhage (SAH). Cerebrolysin, a brain-specific proposed pleiotropic neuroprotective agent, has been suggested to improve global functional outcomes in ischemic stroke. We investigated the efficacy, safet...

journal_title：BMC neurology

authors： Woo PYM,Ho JWK,Ko NMW,Li RPT,Jian L,Chu ACH,Kwan MCL,Chan Y,Wong AKS,Wong HT,Chan KY,Kwok JCK

更新日期：2020-11-03 00:00:00

abstract：BACKGROUND:Spastic paraplegia, optic atrophy and neuropathy (Spoan syndrome) is an autosomal recessive disease with approximately 70 cases recorded in Brazil and Egypt. METHODS:This is a prospective longitudinal study performed with 47 patients affected with Spoan syndrome of seven communities of Rio Grande do Norte (...

journal_title：BMC neurology

authors： Galvão CRC,Cavalcante PMA,Olinda R,Graciani Z,Zatz M,Kok F,Santos S,Lancman S

更新日期：2019-10-27 00:00:00

abstract：BACKGROUND:A fraction of patients with penetrating artery infarction (PAI) experience progressive motor deficit deterioration (PMD). We sought to investigate the role of high-sensitivity C-reactive protein (hs-CRP) at admission in predicting PMD. METHODS:From January 2015 to September 2018, consecutive patients with P...

journal_title：BMC neurology

authors： Gong P,Liu Y,Huang T,Chen W,Jiang T,Gong Y,Lu M,Wang M,Zhang Y,Zhang X,Deng Q,Zhou J

更新日期：2019-12-29 00:00:00

abstract：BACKGROUND:Infectious basilar artery (BA) aneurysm has been occasionally reported to be generated from meningitis following transcranial operation. However, infectious BA aneurysm formed by intracranial infection after endoscopic endonasal operation has never been reported. CASE PRESENTATION:A 53-year-old man who was ...

journal_title：BMC neurology

authors： Wang X,Chen G,Li M,Liang J,Guo H,Song G,Bao Y

更新日期：2020-03-14 00:00:00

abstract：BACKGROUND:There is conflicting information as to whether antiretroviral drugs with better central nervous system (CNS) penetration (neuroHAART) assist in improving neurocognitive function and suppressing cerebrospinal fluid (CSF) HIV RNA. The current review aims to better synthesise existing literature by using an inn...

journal_title：BMC neurology

authors： Cysique LA,Waters EK,Brew BJ

更新日期：2011-11-22 00:00:00

abstract：BACKGROUND:The WHOQOL-BREF is a frequently used instrument for the assessment of health-related quality of life. Unlike other generic instruments used for the assessment of this construct, little is known about its properties in individuals with headache disorders. The present study examines the reliability and factori...

journal_title：BMC neurology

authors： Brzoska P

更新日期：2020-07-03 00:00:00

abstract：BACKGROUND:Lumbo-sacral radiculopathy (LSR) is a common musculoskeletal disorder for which patients seek medical care and referrals for advanced imaging. However, accurate diagnosis remains challenging. Neuropathic pain screening questionnaires, clinical neurological examination and magnetic resonance imaging (MRI) are...

journal_title：BMC neurology

authors： Tawa N,Diener I,Louw Q,Rhoda A

更新日期：2019-05-30 00:00:00

abstract：BACKGROUND:The basal ganglia (BG) are thought to play an important role in the control of eye movements. Accordingly, the broad variety of subtle oculomotor alterations that has been described in Parkinson's disease (PD) are generally attributed to the dysfunction of the BG dopaminergic system. However, the present stu...

journal_title：BMC neurology

authors： Pinkhardt EH,Jürgens R,Lulé D,Heimrath J,Ludolph AC,Becker W,Kassubek J

更新日期：2012-02-29 00:00:00

abstract：BACKGROUND:Due to lack of any curative therapy for ALS, symptomatic treatment and maintenance of quality of life (QoL) is very important. We aimed to characterize the affected domains of QoL in ALS patients and to identify factors which are associated with reduced QoL and increased depression. METHODS:159 ALS patients...

journal_title：BMC neurology

authors： Körner S,Kollewe K,Abdulla S,Zapf A,Dengler R,Petri S

更新日期：2015-05-16 00:00:00

abstract：BACKGROUND:Mechanical thrombectomy was approved by NICE as a treatment for stroke in 2016. However, most of the evidence is from studies conducted during working hours. Only few centres in the UK perform thrombectomies out-of-hours. The Royal Stoke University Hospital (RSUH) has offered thrombectomies over 24 h (24/7) ...

journal_title：BMC neurology

authors： Weddell J,Parr E,Knight S,Muddegowda G,Natarajan I,Chembala J,Ferdinand P,Ahmad N,Pencz Z,Rana S,Warusevitane A,Jadun C,Nayak S,Hashim Z,Augustine A,Sim J,Roffe C

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Interleukin 36 (IL-36) cytokines belong to the IL-1 family and play an important role in some autoimmune diseases. However, the relationship between IL-36 and neuromyelitis optica spectrum disorders (NMOSD) remains unclear. METHODS:We determined serum IL-36α, IL-36β and IL-36γ levels and assessed correlatio...

journal_title：BMC neurology

authors： Yang CS,Zhang QX,Deng Y,Zhou BJ,Zhang LJ,Li LM,Qi Y,Wang J,Yang L,Shi FD

更新日期：2019-08-05 00:00:00

abstract：BACKGROUND:Malignant myoepithelioma is a relatively rare malignant tumor occurring most frequently in the salivary glands. A few isolated cases have been described in other locations, including soft tissue, bone, lung, bronchus, oral cavity, nasopharynx, larynx, and maxillary sinus. Malignant myoepithelioma, however, i...

journal_title：BMC neurology

authors： Hong Y,Guo SX,Chen S,Klebe D,Zhang JM,Wu Q

更新日期：2013-05-04 00:00:00

abstract：BACKGROUND:Women have been reported to show more frequent recanalization and better recovery after intravenous (IV) recombinant tissue plasminogen activator (rt-PA) treatment for acute stroke compared with men. To investigate this we studied a series of stroke patients receiving IV rt-PA and undergoing acute transcrani...

journal_title：BMC neurology

authors： Al-hussain F,Hussain MS,Molina C,Uchino K,Shuaib A,Demchuk AM,Alexandrov AV,Saqqur M,CLOTBUST Investigators.

更新日期：2014-03-26 00:00:00

abstract：BACKGROUND:Migraine is a highly prevalent disorder. The disability provoked by its attacks results in suffering as well as considerable economic and social losses. The objective of migraine acute treatment is to restore the patient to normal function as quickly and consistently as possible. There are numerous drugs ava...

journal_title：BMC neurology

authors： Krymchantowski AV

更新日期：2004-01-28 00:00:00

abstract：BACKGROUND:Although free radicals have been reported to play a role in the expansion of ischemic brain lesions, the effect of free radical scavengers is still under debate. In this study, the temporal profile of ischemic stroke lesion sizes was assessed for more than one year to evaluate the effect of edaravone which m...

journal_title：BMC neurology

authors： Nakase T,Yoshioka S,Suzuki A

更新日期：2011-03-30 00:00:00

abstract：BACKGROUND:Dorsolateral medullary infarction (Wallenberg syndrome) is rare in clinical practice; however, the subsequent corneal lesions are more uncommon. To our knowledge, only one such case was previously reported. We report a similar case with successful treatment and recovery, and analyse both cases to address the...

journal_title：BMC neurology

authors： Wu S,Li N,Xia F,Sidlauskas K,Lin X,Qian Y,Gao W,Zhang Q

更新日期：2014-12-04 00:00:00

abstract：BACKGROUND:Effective control of (upright) body posture requires a proper representation of body orientation. Stroke patients with pusher syndrome were shown to suffer from severely disturbed perception of own body orientation. They experience their body as oriented 'upright' when actually tilted by nearly 20 degrees to...

journal_title：BMC neurology

authors： Johannsen L,Broetz D,Karnath HO

更新日期：2006-08-23 00:00:00

abstract：BACKGROUND:Embolectomy is the standard of care in acute ischemic stroke (AIS) caused by large vessel occlusion (LVO). Aim of this study was to compare two techniques: A Direct Aspiration First Pass Technique (ADAPT) and Stent-retriever Assisted Vacuum-locked Extraction (SAVE) stratified by the occluded vessel. METHODS...

journal_title：BMC neurology

authors： Brehm A,Maus V,Tsogkas I,Colla R,Hesse AC,Gera RG,Psychogios MN

更新日期：2019-04-15 00:00:00

abstract：BACKGROUND:Active Rehabilitation (AR) is a community peer-based concept for people with spinal cord injury (SCI) that is primarily delivered through brief residential training programmes. Despite a plethora of positive anecdotal evidence of AR programmes as life-changing experiences, the effects of AR-programmes have n...

journal_title：BMC neurology

authors： Divanoglou A,Tasiemski T,Jörgensen S

更新日期：2020-01-11 00:00:00

abstract：BACKGROUND:Anterior spinal cord herniation (aSCH) is a rare cause of myelopathy which may present as pure motor syndrome and mimic other degenerative diseases of the spinal cord. In slowly progressive cases, diagnosis may be impeded by equivocal imaging results and mistaken for evolving upper motor neuron disease. As e...

journal_title：BMC neurology

authors： Regensburger M,Schlachetzki JCM,Klekamp J,Doerfler A,Winkler J

更新日期：2020-08-29 00:00:00

abstract：BACKGROUND:Machado-Joseph disease (MJD), or spinocerebellar ataxia type 3 (SCA3), is an autosomal dominant neurodegenerative disorder of late onset, which is caused by a CAG repeat expansion in the coding region of the ATXN3 gene. This disease presents clinical heterogeneity, which cannot be completely explained by the...

journal_title：BMC neurology

authors： Bettencourt C,Santos C,Coutinho P,Rizzu P,Vasconcelos J,Kay T,Cymbron T,Raposo M,Heutink P,Lima M

更新日期：2011-10-24 00:00:00