Interaction of physical function, quality of life and depression in Amyotrophic lateral sclerosis: characterization of a large patient cohort.

abstract：BACKGROUND:While both hypercapnia and hypocapnia are harmful in patients with subarachnoid hemorrhage (SAH), it is unknown whether high-normal PaCO2 values are better than low-normal values. We hypothesized that high-normal PaCO2 values have more detrimental than beneficial effects on outcome. METHODS:Consecutive pati...

journal_title：BMC neurology

authors： Reiff T,Barthel O,Schönenberger S,Mundiyanapurath S

更新日期：2020-01-20 00:00:00

abstract：BACKGROUND:Cognitive impairment commonly occurs in the acute phase post-stroke, but may persist with over half of all stroke survivors experiencing some form of long-term cognitive deficit. Recent evidence suggests that optimising secondary prevention adherence is a critical factor in preventing recurrent stroke and th...

journal_title：BMC neurology

authors： Mellon L,Brewer L,Hall P,Horgan F,Williams D,Hickey A,ASPIRE-S study group.

更新日期：2015-03-12 00:00:00

abstract：:Following the success of recent endovascular trials, endovascular therapy has emerged as an exciting addition to the arsenal of clinical management of patients with acute ischemic stroke (AIS). In this paper, we present an extensive overview of intravenous and endovascular reperfusion strategies, recent advances in AI...

journal_title：BMC neurology

authors： Bhaskar S,Stanwell P,Cordato D,Attia J,Levi C

更新日期：2018-01-16 00:00:00

abstract：BACKGROUND:The study of muscle metabolism by near-infrared spectroscopy (NIRS) has been poorly implemented in multiple sclerosis (MS). Aims of the study were to compare resting muscle oxygen consumption (rmVO2) at gastrocnemius in MS patients and in age-matched healthy controls (HC) measured using NIRS, and to evaluate...

journal_title：BMC neurology

authors： Malagoni AM,Felisatti M,Lamberti N,Basaglia N,Manfredini R,Salvi F,Zamboni P,Manfredini F

更新日期：2013-05-29 00:00:00

abstract：BACKGROUND:Type 2 Diabetes in Mexico has a high prevalence, 16-87% of patients may experience peripheral neuropathy. Early detection can prevent or halt its progression. The performance of Sudoscan in detecting neuropathy was compared to the Michigan Neuropathy Screening Instrument (MNSI). The aim was to identificate s...

journal_title：BMC neurology

authors： Carbajal-Ramírez A,Hernández-Domínguez JA,Molina-Ayala MA,Rojas-Uribe MM,Chávez-Negrete A

更新日期：2019-05-31 00:00:00

abstract：BACKGROUND:Amyotrophic lateral sclerosis is a rapidly progressive neurodegenerative disorder characterised by loss of motor neurons leading to severe weakness and death from respiratory failure within 3-5 years. Riluzole prolongs survival in ALS. A published report has suggested a dramatic effect of lithium carbonate o...

journal_title：BMC neurology

authors： Al-Chalabi A,Shaw PJ,Young CA,Morrison KE,Murphy C,Thornhill M,Kelly J,Steen IN,Leigh PN,UKMND-LiCALS.

更新日期：2011-09-21 00:00:00

abstract：BACKGROUND:Sturge-Weber syndrome (SWS) is a rare and sporadic congenital neurocutaneous disorder, that is characterized by facial venous capillary malformation (port-wine birthmark), leptomeningeal venous malformation (angiomatosis), glaucoma, and neurologic problems. SWS can comorbid with other disorders in some patie...

journal_title：BMC neurology

authors： Deng L,Wang D,Ruan N,Fu P

更新日期：2019-05-03 00:00:00

abstract：BACKGROUND:Despite substantial research into the topic and valiant surgical efforts, reconstruction of peripheral nerve injury remains a challenging surgery. This study was conducted to evaluate the effectiveness of axonal regeneration of a transected sciatic nerve through a vein conduit containing degenerated skeletal...

journal_title：BMC neurology

authors： Mohammadi J,Delaviz H,Mohammadi B,Delaviz H,Rad P

更新日期：2016-11-22 00:00:00

abstract：BACKGROUND:"Anarchic hand" is a rare condition characterised by non-volitional, goal-directed movements of one arm. We report a case with analysis of structural and functional connectivity. CASE PRESENTATION:A 15 year old girl developed intermittent symptoms of intermanual conflict or anarchic hand as a result of trau...

journal_title：BMC neurology

authors： Basu AP,Taylor PN,Lowther E,Forsyth EO,Blamire AM,Forsyth RJ

更新日期：2015-11-14 00:00:00

abstract：BACKGROUND:Central sensitization is thought to be an important contributing factor in many chronic pain disorders. The Central Sensitization Inventory (CSI) is a patient-reported measure frequently used to assess symptoms related to central sensitization. The aims of the study were to translate and cross-culturally ada...

journal_title：BMC neurology

authors： Sharma S,Jha J,Pathak A,Neblett R

更新日期：2020-07-27 00:00:00

abstract：:In clinical neurology, a comprehensive understanding of consciousness has been regarded as an abstract concept--best left to philosophers. However, times are changing and the need to clinically assess consciousness is increasingly becoming a real-world, practical challenge. Current methods for evaluating altered level...

journal_title：BMC neurology

authors： Gawryluk JR,D'Arcy RC,Connolly JF,Weaver DF

更新日期：2010-01-29 00:00:00

abstract：BACKGROUND:Anterior spinal cord herniation (aSCH) is a rare cause of myelopathy which may present as pure motor syndrome and mimic other degenerative diseases of the spinal cord. In slowly progressive cases, diagnosis may be impeded by equivocal imaging results and mistaken for evolving upper motor neuron disease. As e...

journal_title：BMC neurology

authors： Regensburger M,Schlachetzki JCM,Klekamp J,Doerfler A,Winkler J

更新日期：2020-08-29 00:00:00

abstract：BACKGROUND:Recent studies suggest that epigenetic factors may play an important role in the pathogenesis of Parkinson's disease (PD). In our previous work, we sequenced the exomes of sixteen patients from eight Chinese PD families using whole exome sequencing technology, consequently three patients from different pedig...

journal_title：BMC neurology

authors： Liao XX,Zhan ZX,Luo YY,Li K,Wang JL,Guo JF,Yan XX,Xia K,Tang BS,Shen L

更新日期：2013-12-11 00:00:00

abstract：BACKGROUND:The partial form of the complex regional pain syndrome of the hand type 1 (CRPS 1), involving only 1 to 3 fingers, is a rare condition first described in 1972. The aim of the study is to define more precisely the diagnosis workup and the prognosis of this clinical entity. METHODS:Retrospective study of CRPS...

journal_title：BMC neurology

authors： Konzelmann M,Deriaz O,Luthi F

更新日期：2013-03-18 00:00:00

abstract：BACKGROUND:Muscular weakness in myasthenia gravis (MG) is commonly assessed using Quantitative Myasthenia Gravis Score (QMG). More objective and quantitative measures may complement the use of clinical scales and might detect subclinical affection of muscles. We hypothesized that muscular weakness in patients with MG c...

journal_title：BMC neurology

authors： Hoffmann S,Siedler J,Brandt AU,Piper SK,Kohler S,Sass C,Paul F,Reilmann R,Meisel A

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:Cognitive disorders, such as memory disturbances, are often observed following a subarachnoid hemorrhage. We present a very rare case where rupture of a posterior cerebral artery aneurysm caused restricted damage to the hippocampus unilaterally, and caused memory disturbances. CASE PRESENTATION:A 56-year-ol...

journal_title：BMC neurology

authors： Maeshima S,Osawa A,Yamane F,Shimaguchi H,Ochiai I,Yoshihara T,Uemiya N,Kanazawa R,Ishihara S

更新日期：2014-03-07 00:00:00

abstract：BACKGROUND:The character of upper limb disorder in computer operators is subject to debate. A peripheral nerve-involvement is suggested from the common presence of a triad of symptoms consisting of pain, paraestesiae and subjective weakness, and from physical findings suggesting neuropathy. This study aimed to examine ...

journal_title：BMC neurology

authors： Jepsen JR,Thomsen G

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The WHOQOL-BREF is a frequently used instrument for the assessment of health-related quality of life. Unlike other generic instruments used for the assessment of this construct, little is known about its properties in individuals with headache disorders. The present study examines the reliability and factori...

journal_title：BMC neurology

authors： Brzoska P

更新日期：2020-07-03 00:00:00

abstract：BACKGROUND:Friedreich ataxia is a neurological disease originating from an iron-sulfur cluster enzyme deficiency due to impaired iron handling in the mitochondrion, aconitase being particularly affected. As a mean to counteract disease progression, it has been suggested to chelate free mitochondrial iron. Recent years ...

journal_title：BMC neurology

authors： Goncalves S,Paupe V,Dassa EP,Rustin P

更新日期：2008-06-16 00:00:00

abstract：BACKGROUND:Decision-making is an essential function of everyday life. Decision-making under explicit risk requires developing advantageous decision strategies based on fixed outcomes (e.g., probabilities of winning or losing a bet). Decision-making and its neural substrates have been rarely studied in MS. We expected p...

journal_title：BMC neurology

authors： Radomski AD,Power C,Purdon SE,Emery DJ,Blevins G,Warren KG,Fujiwara E

更新日期：2015-04-23 00:00:00

abstract：BACKGROUND:Malignant myoepithelioma is a relatively rare malignant tumor occurring most frequently in the salivary glands. A few isolated cases have been described in other locations, including soft tissue, bone, lung, bronchus, oral cavity, nasopharynx, larynx, and maxillary sinus. Malignant myoepithelioma, however, i...

journal_title：BMC neurology

authors： Hong Y,Guo SX,Chen S,Klebe D,Zhang JM,Wu Q

更新日期：2013-05-04 00:00:00

abstract：BACKGROUND:Different apoptosis pathways activate caspase-3. In a study involving 27 patients with traumatic brain injury (TBI), higher caspase-3 levels were found in contusion brain tissue resected from non-survivors than from survivors. The objective of this study was to determine whether there is an association in TB...

journal_title：BMC neurology

authors： Lorente L,Martín MM,Argueso M,Ramos L,Solé-Violán J,Riaño-Ruiz M,Jiménez A,Borreguero-León JM

更新日期：2015-11-06 00:00:00

abstract：BACKGROUND:The two human cerebral hemispheres are continuously interacting, through excitatory and inhibitory influences and one critical structure subserving this interhemispheric balance is the corpus callosum. Interhemispheric neurophysiological abnormalities and intrahemispheric behavioral impairments have been rep...

journal_title：BMC neurology

authors： Fecteau S,Lassonde M,Théoret H

更新日期：2006-06-21 00:00:00

abstract：BACKGROUND:Patients with acute stroke are particularly vulnerable to delirium episodes. Although delirium detection is important, no evidence-based recommendations have been established to date on how these patients should be routinely screened for delirium or which tool should be used for this purpose in this populati...

journal_title：BMC neurology

authors： Mansutti I,Saiani L,Palese A

更新日期：2019-12-02 00:00:00

abstract：BACKGROUND:To evaluate the relationship between the flow signal intensity of branch arteries distal to the stenosis on 3-dimensional (3D) time-of-flight (TOF) magnetic resonance angiography (MRA) and the risk of stroke recurrence in patients with severe middle cerebral artery (MCA) trunk stenosis. METHODS:We prospecti...

journal_title：BMC neurology

authors： Chen H,Li Z,Hong H,Xing S,Liu G,Zhang A,Tan S,Zhang J,Zeng J

更新日期：2015-09-16 00:00:00

abstract：BACKGROUND:Epilepsy is a major complication of stroke. We aimed to establish whether there is an association between intravenous thrombolysis, intra-arterial thrombolysis and post stroke seizure (PSS) development. Improved understanding of the relationship between reperfusion therapies and seizure development may impro...

journal_title：BMC neurology

authors： Naylor J,Thevathasan A,Churilov L,Guo R,Xiong Y,Koome M,Chen Z,Chen Z,Liu X,Kwan P,Campbell BCV

更新日期：2018-05-03 00:00:00

abstract：BACKGROUND:To describe the clinical phenotype of paroxysmal extreme pain disorder, an autosomal dominant condition in four members in one family with the mutation NM_002977.3:c.3892G > T (p.Val1298Phe) in the SCN9A gene. Clinical examinations and details from members of one Polish family were collected, including age a...

journal_title：BMC neurology

authors： Stępień A,Sałacińska D,Staszewski J,Durka-Kęsy M,Dobrogowski J

更新日期：2020-05-13 00:00:00

abstract：BACKGROUND:Glutamic acid decarboxylase (GAD) is the rate-limiting enzyme for producing γ-aminobutyric acid, and it has been suggested that antibodies against GAD play a role in neurological conditions and type 1 diabetes. However, it is not known whether dementia appears as the sole neurological manifestation associate...

journal_title：BMC neurology

authors： Takagi M,Yamasaki H,Endo K,Yamada T,Kaneko K,Oka Y,Mori E

更新日期：2011-12-21 00:00:00

abstract：:Following publication of the original article [1], the authors reported an error in Table 2 wherein the item numbering in the first column is wrong. ...

journal_title：BMC neurology

authors： da Silva ESM,Santos GL,Catai AM,Borstad A,Furtado NPD,Aniceto IAV,Russo TL

更新日期：2019-09-13 00:00:00

abstract：BACKGROUND:Cerebral amyloid angiopathy (CAA) is characterized by the deposition of ß-amyloid peptides (Aß) in and surrounding the wall of microvasculature in the central nervous system, together with parenchymal amyloid plaques collectively referred to as cerebral amyloidosis, which occurs in the brain commonly among t...

journal_title：BMC neurology

authors： Li JM,Huang LL,Liu F,Tang BS,Yan XX

更新日期：2017-08-25 00:00:00