Idiopathic inflammatory myopathy comorbid with Sturge-Weber syndrome: a case report.

abstract：BACKGROUND:MS-pathogenesis is known to involve both multiple environmental events, and several independent genetic risk-factors. METHODS:A model of susceptibility is developed and a mathematical analysis undertaken to elucidate the nature of genetic susceptibility to MS and to understand the constraints that are place...

journal_title：BMC neurology

authors： Goodin DS

更新日期：2010-10-28 00:00:00

abstract：BACKGROUND:Headache is a common complaint in children and adolescents. Recently, an increased prevalence of headache in children and adolescents has been reported. METHODS:We retrospectively reviewed the medical records of children and adolescents attending the Headache Clinic of Daejeon St. Mary's Hospital during the...

journal_title：BMC neurology

authors： Jeong YJ,Lee YT,Lee IG,Han JY

更新日期：2018-05-21 00:00:00

abstract：BACKGROUND:A number of emerging studies have evaluated clot composition in acute ischemic stroke. Studies of clot composition of embolic strokes of undetermined strokes are lacking. OBJECTIVES:We sought to analyze the RBC to platelet ratios in clots and correlated our findings with stroke etiology. METHODS:This was a...

journal_title：BMC neurology

authors： Nouh A,Mehta T,Hussain M,Song X,Ollenschleger M

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:The clinical impact of neutralizing antibodies against interferon-beta (NAb) is controversial. Their presence can lead to a decrease in interferon-beta (IFNβ) efficacy. Fatigue reported in patients with multiple sclerosis (MS) may be associated with an unfavorable clinical course. We conducted a prospective ...

journal_title：BMC neurology

authors： Manceau P,Latarche C,Pittion S,Edan G,de Sèze J,Massart C,Debouverie M

更新日期：2014-11-30 00:00:00

abstract：BACKGROUND:The clinical features of Alzheimer's disease (AD) are related to brain network degeneration, and hyperhomocysteinemia is related to greater white matter hyperintensities. We investigated the changes in four diffusion tensor imaging parameters in the white matter of patients with early stage AD, examined thei...

journal_title：BMC neurology

authors： Lee CC,Hsu SW,Huang CW,Chang WN,Chen SF,Wu MK,Chang CC,Hwang LC,Chen PC

更新日期：2017-10-06 00:00:00

abstract：BACKGROUND:Stroke increases the risk of cognitive impairment even several years after the stroke event. The exact mechanisms of post-stroke cognitive decline are unclear, but the immunological response to stroke might play a role. The aims of the StrokeCog study are to examine the associations between immunological res...

journal_title：BMC neurology

authors： Drag LL,Mlynash M,Nassar H,Osborn E,Kim DE,Angst MS,Aghaeepour N,Buckwalter M,Lansberg MG

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:Patients with multiple sclerosis (MS) have a decreased frequency of CD8+ T cells reactive to their own Epstein-Barr virus (EBV) infected B cells. We have proposed that this might predispose to the development of MS by allowing EBV-infected autoreactive B cells to accumulate in the central nervous system. The...

journal_title：BMC neurology

authors： Pender MP,Csurhes PA,Pfluger CM,Burrows SR

更新日期：2011-08-03 00:00:00

abstract：BACKGROUND:Cerebral microvascular abnormality is frequently associated with lacunar and subcortical ischemic lesions. We performed acute and follow-up CT perfusion scans over the first 3 months after ischemic stroke to investigate disturbances of the blood-brain barrier (BBB) and cerebral perfusion in patients with lac...

journal_title：BMC neurology

authors： Yang J,d'Esterre C,Ceruti S,Roversi G,Saletti A,Fainardi E,Lee TY

更新日期：2015-10-22 00:00:00

abstract：BACKGROUND:An Early Supported Discharge (ESD) and rehabilitation from a coordinated team in the home environment is recommended in several high-income countries for patients with mild to moderate symptoms after stroke. Returning home from the hospital takes place very early in Sweden today (12 days post stroke), thus t...

journal_title：BMC neurology

authors： Nordin Å,Sunnerhagen KS,Axelsson ÅB

更新日期：2015-11-16 00:00:00

abstract：BACKGROUND:The etiologic determinants of stroke in young adults remain a diagnostic challenge in up to one-fourth of cases. Increasing evidences led to consider Fabry's disease (FD) as a possible cause to check up. We aimed at evaluating the prevalence of unrecognized FD in a cohort of patients with juvenile stroke in ...

journal_title：BMC neurology

authors： Fancellu L,Borsini W,Romani I,Pirisi A,Deiana GA,Sechi E,Doneddu PE,Rassu AL,Demurtas R,Scarabotto A,Cassini P,Arbustini E,Sechi G

更新日期：2015-12-12 00:00:00

abstract：BACKGROUND:Deep vein thrombosis (DVT) is an important complication of ischemic stroke, although the incidence of DVT is regarded as being lower in Asian than in non-Asian patients. Here, we investigated the incidence and factors associated with DVT in Asian patients with ischemic stroke. METHODS:Acute ischemic stroke ...

journal_title：BMC neurology

authors： Ha SH,Kim YJ,Heo SH,Chang DI,Kim BJ

更新日期：2020-06-27 00:00:00

abstract：BACKGROUND:Neuroprotective strategies after cardiopulmonary resuscitation are currently the focus of experimental and clinical research. Levosimendan has been proposed as a promising drug candidate because of its cardioprotective properties, improved haemodynamic effects in vivo and reduced traumatic brain injury in vi...

journal_title：BMC neurology

authors： Roehl AB,Zoremba N,Kipp M,Schiefer J,Goetzenich A,Bleilevens C,Kuehn-Velten N,Tolba R,Rossaint R,Hein M

更新日期：2012-08-24 00:00:00

abstract：BACKGROUND:Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis of unknown cause involving the brain and accompanied by prominent eosinophilia. Intracardiac thrombosis is a major cardiac complication of EGPA that may cause thromboembolism. CASE PRESENTATION:A 53-year-old man presenting wi...

journal_title：BMC neurology

authors： Hira K,Shimura H,Kamata R,Takanashi M,Hashizume A,Takahashi K,Sugiyama M,Izumi H,Hattori N,Urabe T

更新日期：2019-11-15 00:00:00

abstract：BACKGROUND:"Anarchic hand" is a rare condition characterised by non-volitional, goal-directed movements of one arm. We report a case with analysis of structural and functional connectivity. CASE PRESENTATION:A 15 year old girl developed intermittent symptoms of intermanual conflict or anarchic hand as a result of trau...

journal_title：BMC neurology

authors： Basu AP,Taylor PN,Lowther E,Forsyth EO,Blamire AM,Forsyth RJ

更新日期：2015-11-14 00:00:00

abstract：BACKGROUND:Spinal cerebrospinal fluid (CSF) leak can lead to intracranial hypotension and is an important differential diagnosis to consider in patients with sudden-onset chronic daily headaches. Pars interarticularis (PI) fracture is a potential rare cause of suspected spinal CSF leak. METHODS:This is a retrospective...

journal_title：BMC neurology

authors： Chan TLH,Cowan R,Hindiyeh N,Hashmi S,Lanzman B,Carroll I

更新日期：2020-04-29 00:00:00

abstract：BACKGROUND:Dopaminergic neuronal loss begins years before motor symptoms appear in Parkinson disease (PD). Thus, reliable biomarkers for early diagnosis and prognosis of PD are an essential pre-requisite to develop disease modifying therapies. Inflammation-derived oxidative stress is postulated to contribute to nigrost...

journal_title：BMC neurology

authors： Rathnayake D,Chang T,Udagama P

更新日期：2019-04-06 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) is associated with vascular risk factors; brain ischemia facilitates the pathogenesis of AD. Recent studies have suggested that the reduction of AD risk with statin was achieved by decreased amyloidogenic amyloid precursor protein. METHODS:We used mitochondrial transgenic neuronal c...

journal_title：BMC neurology

authors： Jeong JH,Yum KS,Chang JY,Kim M,Ahn JY,Kim S,Lapchak PA,Han MK

更新日期：2015-07-31 00:00:00

abstract：BACKGROUND:Study aimed at investigation of pathogenic role and prognostic value of several selected cerebrospinal fluid acute phase factors that can reflect the severity of ischemic brain damage. METHODS:Ninety five acute ischemic stroke patients were investigated. Ischemic region visualized at the twenty fourth hour ...

journal_title：BMC neurology

authors： Beridze M,Sanikidze T,Shakarishvili R,Intskirveli N,Bornstein NM

更新日期：2011-03-30 00:00:00

abstract：BACKGROUND:Parkinson's disease, the second most common neurodegenerative disease, is diagnostically defined by motor impairments, but also includes often under-recognized impairments in cognition, mood, sleep, and the autonomic nervous system. These problems can severely affect individuals' quality of life. In our prio...

journal_title：BMC neurology

authors： Connor K,Cheng E,Siebens HC,Lee ML,Mittman BS,Ganz DA,Vickrey B

更新日期：2015-12-15 00:00:00

abstract：BACKGROUND:Autonomic nervous system (ANS) dysfunction is present in up to one third of patients with tetanus. The prognostic value of ANS dysfunction is known in severe tetanus but its value is not well established in mild to moderate tetanus. METHODS:Medical records of all patients admitted with tetanus at two academ...

journal_title：BMC neurology

authors： Wasay M,Khealani BA,Talati N,Shamsi R,Syed NA,Salahuddin N

更新日期：2005-01-31 00:00:00

abstract：BACKGROUND:Multiple pathogenic factors may contribute to the pathophysiology of Alzheimer's disease (AD). Peripheral blood markers have been used to assess biochemical changes associated with AD and mild cognitive impairment (MCI) and involved in their pathophysiology. METHODS:Plasma samples and clinical data were obt...

journal_title：BMC neurology

authors： Kim SM,Song J,Kim S,Han C,Park MH,Koh Y,Jo SA,Kim YY

更新日期：2011-05-12 00:00:00

abstract：BACKGROUND:It has been recently demonstrated that in Frontotemporal Lobar Degeneration (FTLD) memory deficits at presentation are commoner than previously thought. Apolipoprotein E (ApoE) genotype, the major genetic risk factor in sporadic late-onset Alzheimer Disease (AD), modulates cerebral perfusion in late middle-a...

journal_title：BMC neurology

authors： Borroni B,Perani D,Archetti S,Agosti C,Paghera B,Bellelli G,Di Luca M,Padovani A

更新日期：2006-08-24 00:00:00

abstract：BACKGROUND:Sciatica is a condition that is characterised by radicular pain in the leg and primarily caused by a herniated lumbar intervertebral disk. In addition to leg pain, patients can experience back pain, leg numbness and leg weakness resulting in decreased productivity and social activity. The majority of sciatic...

journal_title：BMC neurology

authors： Verheijen E,Munts AG,van Haagen O,de Vries D,Dekkers O,van den Hout W,Vleggeert-Lankamp C

更新日期：2019-09-03 00:00:00

abstract：BACKGROUND:Vascular cognitive impairment-no dementia (VCIND) refers to the early or mild cognitive impairment induced by cerebral vascular injury. Research shows that serum total homocysteine (tHcy) level is an independent risk factor for cerebral vascular disease and may be closely related to cognitive function.Curren...

journal_title：BMC neurology

authors： Jiang B,Chen Y,Yao G,Yao C,Zhao H,Jia X,Zhang Y,Ge J,Qiu E,Ding C

更新日期：2014-11-30 00:00:00

abstract：BACKGROUND:Gait ability and cognitive function are interrelated during both normal walking (NW) and dual-task walking (DTW), and gait ability is thus adversely affected by cognitive impairment in both situations. However, this association is insufficiently understood in people with mild cognitive impairment (MCI). Here...

journal_title：BMC neurology

authors： Doi T,Shimada H,Makizako H,Tsutsumimoto K,Uemura K,Anan Y,Suzuki T

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Epidemiology of acute stroke in developing countries differs from that in the developed world, for example, the age at stroke, risk factors, subtypes of stroke and prognosis. Hypertension remains a dominant risk factor and prognostic indicator in patients with stroke in all communities. The risk of stroke is...

journal_title：BMC neurology

authors： Jain S,Namboodri KK,Kumari S,Prabhakar S

更新日期：2004-01-06 00:00:00

abstract：:The advent of early absorption, distribution, metabolism, excretion, and toxicity (ADMET) screening has increased the attrition rate of weak drug candidates early in the drug-discovery process, and decreased the proportion of compounds failing in clinical trials for ADMET reasons. This paper reviews the history of ADM...

journal_title：BMC neurology

authors： Tsaioun K,Bottlaender M,Mabondzo A,Alzheimer's Drug Discovery Foundation.

更新日期：2009-06-12 00:00:00

abstract：BACKGROUND:Phase I/II placebo-controlled clinical trials of recombinant Factor VIIa (rFVIIa) suggested that administration of rFVIIa within 4 hours after onset of intracerebral hemorrhage (ICH) is safe, limits ICH growth, and improves outcomes. We sought to determine the cost-effectiveness of rFVIIa for acute ICH treat...

journal_title：BMC neurology

authors： Kissela BM,Eckman MH

更新日期：2008-05-19 00:00:00

abstract：BACKGROUND:This study aims to investigate the clinical value of two kinds of vestibular-evoked myogenic potentials in patients with sudden sensorineural hearing loss (SSNHL). METHODS:A total of 82 patients were divided into two groups: vertigo group and non-vertigo group. All patients underwent examinations for pure t...

journal_title：BMC neurology

authors： Wang Y,Gu ST,Bao XL,Guo JL

更新日期：2019-12-21 00:00:00

abstract：BACKGROUND:Balanced Steady State Free Precession (b-SSFP) sequences and the newly developed Fast-Spin-Echo (FSE)-sequences enable an optimized visualization of neurovascular compression (NVC) in patients with trigeminal neuralgia (TN). Arterial conflicts are mostly associated with a favorable outcome of microvascular d...

journal_title：BMC neurology

authors： Müller S,Khadhraoui E,Khanafer A,Psychogios M,Rohde V,Tanrikulu L

更新日期：2020-07-14 00:00:00