Effects of differences in serum total homocysteine, folate, and vitamin B12 on cognitive impairment in stroke patients.

abstract：BACKGROUND:It has been recently demonstrated that in Frontotemporal Lobar Degeneration (FTLD) memory deficits at presentation are commoner than previously thought. Apolipoprotein E (ApoE) genotype, the major genetic risk factor in sporadic late-onset Alzheimer Disease (AD), modulates cerebral perfusion in late middle-a...

journal_title：BMC neurology

authors： Borroni B,Perani D,Archetti S,Agosti C,Paghera B,Bellelli G,Di Luca M,Padovani A

更新日期：2006-08-24 00:00:00

abstract：BACKGROUND:The aim of this study was to assess the diagnostic accuracy (sensitivity and specificity) of clinical, imaging and motor evoked potentials (MEP) for predicting the short-term prognosis of multiple sclerosis (MS). METHODS:We obtained clinical data, MRI and MEP from a prospective cohort of 51 patients and 20 ...

journal_title：BMC neurology

authors： Bejarano B,Bianco M,Gonzalez-Moron D,Sepulcre J,Goñi J,Arcocha J,Soto O,Del Carro U,Comi G,Leocani L,Villoslada P

更新日期：2011-06-07 00:00:00

abstract：BACKGROUND:Evidence indicates that the continuation of therapy among community-dwelling stroke survivors improves physical function. Community rehabilitation programmes often face limitations in terms of resources. It is imperative to include new motivational interventions to encourage some level of non-clinician manag...

journal_title：BMC neurology

authors： Singh DK,Mohd Nordin NA,Abd Aziz NA,Lim BK,Soh LC

更新日期：2013-12-13 00:00:00

abstract：BACKGROUND:Elevated intracranial pressure from cerebral edema is the major cause of early mortality in acute stroke. Current treatment strategies to limit cerebral edema are not particularly effective. Some novel anti-edema measures have shown promising early findings in experimental stroke models. Vasopressin antagoni...

journal_title：BMC neurology

authors： Hedna VS,Bidari S,Gubernick D,Ansari S,Satriotomo I,Khan AA,Qureshi AI

更新日期：2014-11-18 00:00:00

abstract：BACKGROUND:IncobotulinumtoxinA (Xeomin®) is a botulinum neurotoxin type A with established efficacy in the treatment of upper-limb spasticity in adults. This retrospective case series in a university hospital setting aimed to elucidate the safety and tolerability of incobotulinumtoxinA for treatment of spasticity in ch...

journal_title：BMC neurology

authors： León-Valenzuela A,Palacios JS,Del Pino Algarrada R

更新日期：2020-04-08 00:00:00

abstract：BACKGROUND:Several environmental exposures, including infection with Epstein-Barr virus, low levels of vitamin D and smoking are established risk factors for multiple sclerosis (MS). Also, high hygienic standard and infection with parasites have been proposed to influence MS risk. The aim of this study was to investiga...

journal_title：BMC neurology

authors： Gustavsen MW,Page CM,Moen SM,Bjølgerud A,Berg-Hansen P,Nygaard GO,Sandvik L,Lie BA,Celius EG,Harbo HF

更新日期：2014-10-03 00:00:00

abstract：BACKGROUND:Multiple sclerosis is a chronic, incurable, demyelinating disease that requires long-term treatment. Rates of non-adherence to prescribed therapy of up to 50% have been reported for chronic diseases. Strategies to improve treatment adherence are therefore of the utmost importance. This study will evaluate th...

journal_title：BMC neurology

authors： Zettl UK,Bauer-Steinhusen U,Glaser T,Hechenbichler K,Limmroth V,Study Group.

更新日期：2013-09-06 00:00:00

abstract：BACKGROUND:The study of muscle metabolism by near-infrared spectroscopy (NIRS) has been poorly implemented in multiple sclerosis (MS). Aims of the study were to compare resting muscle oxygen consumption (rmVO2) at gastrocnemius in MS patients and in age-matched healthy controls (HC) measured using NIRS, and to evaluate...

journal_title：BMC neurology

authors： Malagoni AM,Felisatti M,Lamberti N,Basaglia N,Manfredini R,Salvi F,Zamboni P,Manfredini F

更新日期：2013-05-29 00:00:00

abstract：BACKGROUND:Due to lack of any curative therapy for ALS, symptomatic treatment and maintenance of quality of life (QoL) is very important. We aimed to characterize the affected domains of QoL in ALS patients and to identify factors which are associated with reduced QoL and increased depression. METHODS:159 ALS patients...

journal_title：BMC neurology

authors： Körner S,Kollewe K,Abdulla S,Zapf A,Dengler R,Petri S

更新日期：2015-05-16 00:00:00

abstract：BACKGROUND:Patients often report neurocognitive difficulties after neuroborreliosis (NB). The frequency and extent of cognitive problems in European patients have been studied incompletely. METHODS:Sixty patients received a neurological and neuropsychological work-up 6 months or longer after treatment for proven NB. Q...

journal_title：BMC neurology

authors： Schmidt H,Djukic M,Jung K,Holzgraefe M,Dechent P,von Steinbüchel N,Blocher J,Eiffert H,Schmidt-Samoa C

更新日期：2015-08-19 00:00:00

abstract：BACKGROUND:Patients with Mild Cognitive Impairment (MCI) are at high risk of progression to Alzheimer's dementia. Identifying MCI individuals with high likelihood of conversion to dementia and the associated biosignatures has recently received increasing attention in AD research. Different biosignatures for AD (neuroim...

journal_title：BMC neurology

authors： Ye J,Farnum M,Yang E,Verbeeck R,Lobanov V,Raghavan N,Novak G,DiBernardo A,Narayan VA,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2012-06-25 00:00:00

abstract：BACKGROUND:Complications after stroke have been associated with poor outcome. Modern stroke treatment might reduce the occurrence of complications. The aim of this study was to investigate whether the frequency and type of complications during the first week after stroke has changed in patients treated in a stroke unit...

journal_title：BMC neurology

authors： Bovim MR,Askim T,Lydersen S,Fjærtoft H,Indredavik B

更新日期：2016-08-11 00:00:00

abstract：BACKGROUND:A Transient Ischaemic Attack (TIA) bears a high risk of a subsequent ischaemic stroke. Adequate diagnosis of a TIA should be followed immediately by the start of appropriate preventive therapy, including antiplatelets. The diagnosis of a TIA based on symptoms and signs only is notoriously difficult and bioma...

journal_title：BMC neurology

authors： Dolmans LS,Rutten FH,El Bartelink ML,Seppenwoolde G,van Delft S,Kappelle LJ,Hoes AW

更新日期：2015-07-28 00:00:00

abstract：BACKGROUND:Recent consensus guidelines recommend pregabalin as a first-tier treatment for painful diabetic peripheral neuropathy (DPN). We evaluated the efficacy of pregabalin 600 mg/d (300 mg dosed BID) versus placebo for relieving DPN-associated neuropathic pain, and assessed its safety using objective measures of ne...

journal_title：BMC neurology

authors： Arezzo JC,Rosenstock J,Lamoreaux L,Pauer L

更新日期：2008-09-16 00:00:00

abstract：BACKGROUND:Spinal cord infarction (SCI) is rarely caused by vertebral artery dissection (VAD), which is an important cause of posterior circulation stroke in young and middle-aged patients. We report the case of a middle-aged patient without obvious risk factors for atherosclerosis who had SCI from right VAD. CASE PRE...

journal_title：BMC neurology

authors： Meng YY,Dou L,Wang CM,Kong DZ,Wei Y,Wu LS,Yang Y,Zhou HW

更新日期：2019-12-12 00:00:00

abstract：BACKGROUND:Many migraineurs who seek care in headache clinics are refractory to treatment, despite advances in headache therapies. Epidemiology is poorly characterized, because diagnostic criteria for refractory migraine were not available until recently. We aimed to determine the frequency of refractory migraine in pa...

journal_title：BMC neurology

authors： Irimia P,Palma JA,Fernandez-Torron R,Martinez-Vila E

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:This study aimed to investigate the prevalence and clinical relevance of chronic cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis (MS) patients and healthy controls using extra- and intracranial colour Doppler sonography. METHODS:We examined 146 MS patients, presenting with a clinically isol...

journal_title：BMC neurology

authors： Lanzillo R,Mancini M,Liuzzi R,Di Donato O,Salvatore E,Maglio V,Vacca G,Amato L,D'Anna G,Brunetti A,Brescia Morra V

更新日期：2013-02-13 00:00:00

abstract：BACKGROUND:Human serum paraoxonase 1 (PON1) plays a major role in the metabolism of several organophosphorus compounds. The enzyme is encoded by the polymorphic gene PON1, located on chromosome 7q21.3. Aiming to identify genetic variations related to the risk of developing brain tumors, we investigated the putative ass...

journal_title：BMC neurology

authors： Martínez C,Molina JA,Alonso-Navarro H,Jiménez-Jiménez FJ,Agúndez JA,García-Martín E

更新日期：2010-08-19 00:00:00

abstract：BACKGROUND:Active Rehabilitation (AR) is a community peer-based concept for people with spinal cord injury (SCI) that is primarily delivered through brief residential training programmes. Despite a plethora of positive anecdotal evidence of AR programmes as life-changing experiences, the effects of AR-programmes have n...

journal_title：BMC neurology

authors： Divanoglou A,Tasiemski T,Jörgensen S

更新日期：2020-01-11 00:00:00

abstract：BACKGROUND:Clinical reasoning in Neurology is based on general associations which help to deduce the site of the lesion. However, even "golden principles" may occasionally be deceptive. Here, we describe the case of subacute flaccid tetraparesis due to motor cortical lesions. To our knowledge, this is the first report ...

journal_title：BMC neurology

authors： Zeller D,Heidemeier A,Grigoleit GU,Müllges W

更新日期：2017-02-10 00:00:00

abstract：BACKGROUND:Given the increasing emphasis on the community management of spinal cord injury (SCI), strategies that could be developed and implemented in order to empower and engage individuals with SCI in promoting their health and minimizing the risk of health conditions are required. A self-management program could be...

journal_title：BMC neurology

authors： Munce SE,Fehlings MG,Straus SE,Nugaeva N,Jang E,Webster F,Jaglal SB

更新日期：2014-10-21 00:00:00

abstract：BACKGROUND:Facioscapulohumeral muscular dystrophy (FSHD) is a dominantly-inherited progressive muscular dystrophy caused by de-repression of the DUX4 gene, which causes disease by a toxic-gain-of-function. As molecularly targeted drugs move from preclinical testing into human trials, it is essential that we validate cl...

journal_title：BMC neurology

authors： LoRusso S,Johnson NE,McDermott MP,Eichinger K,Butterfield RJ,Carraro E,Higgs K,Lewis L,Mul K,Sacconi S,Sansone VA,Shieh P,van Engelen B,Wagner K,Wang L,Statland JM,Tawil R,ReSolve Investigators and the FSHD CTRN18.

更新日期：2019-09-10 00:00:00

abstract：BACKGROUND:The coexistence of distinct neurodegenerative diseases in single cases has recently attracted greater attention. The phenotypic co-occurrence of progressive supranuclear palsy (PSP) and amyotrophic lateral sclerosis (ALS) has been documented in several cases. That said, the clinicopathological comorbidity of...

journal_title：BMC neurology

authors： Fujita K,Matsubara T,Miyamoto R,Sumikura H,Takeuchi T,Maruyama Saladini K,Kawarai T,Nodera H,Udaka F,Kume K,Morino H,Kawakami H,Hasegawa M,Kaji R,Murayama S,Izumi Y

更新日期：2019-07-18 00:00:00

abstract：BACKGROUND:Dorsolateral medullary infarction is a typical cerebral infarction which is characterized by Wallenberg's syndrome. Neurotrophic keratopathy is an uncommon consequence of dorsolateral medullary infarction. At present, the protocol is aimed to study the dynamic changes in corneal innervation and the ocular su...

journal_title：BMC neurology

authors： Wang J,Liu P,Liu Z,Tian Y,Zhang G,Guo J,Li L,Liu Z,Han Z,Lin W,Lin X,Lu Q,Liu Y,Chang Q,Wu S

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND:Myasthenic crisis is the most serious life-threatening event in generalized myasthenia gravis (MG) patients. The objective of this study was to assess the long-term impact of thymectomy on rate and severity of these attacks in Iranian patients. METHODS:We reviewed the clinical records from 272 myasthenic pa...

journal_title：BMC neurology

authors： Soleimani A,Moayyeri A,Akhondzadeh S,Sadatsafavi M,Tavakoli Shalmani H,Soltanzadeh A

更新日期：2004-09-11 00:00:00

abstract：BACKGROUND:Hemifacial atrophy (Parry-Romberg syndrome) is a relatively rare disease. The etiology of the disease is not clear. Some authors postulate its relation with limited scleroderma linearis. Linear scleroderma "en coup de sabre" is characterized by clinical presence of most commonly one-sided linear syndrome. In...

journal_title：BMC neurology

authors： Bergler-Czop B,Lis-Swiety A,Brzezińska-Wcisło L

更新日期：2009-07-27 00:00:00

abstract：BACKGROUND:Glutamic acid decarboxylase (GAD) is the rate-limiting enzyme for producing γ-aminobutyric acid, and it has been suggested that antibodies against GAD play a role in neurological conditions and type 1 diabetes. However, it is not known whether dementia appears as the sole neurological manifestation associate...

journal_title：BMC neurology

authors： Takagi M,Yamasaki H,Endo K,Yamada T,Kaneko K,Oka Y,Mori E

更新日期：2011-12-21 00:00:00

abstract：BACKGROUND:The impact of comorbidity on multiple sclerosis (MS) is a new area of interest. Limited data on the risk factors of metabolic syndrome (MetS) is currently available. The aim of this study was to estimate the presence of comorbid conditions and MetS in a sample of adult patients with MS. METHODS:A retrospect...

journal_title：BMC neurology

authors： Sicras-Mainar A,Ruíz-Beato E,Navarro-Artieda R,Maurino J

更新日期：2017-07-17 00:00:00

abstract：BACKGROUND:Overweight is reported as a side effect of SDR. The aims were to study the development of weight, height and body mass index (BMI) during five years after SDR. METHODS:This prospective, longitudinal and practice-based study included all 56 children with CP spastic diplegia undergoing SDR from the start in M...

journal_title：BMC neurology

authors： Westbom L,Lundkvist Josenby A,Wagner P,Nordmark E

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Silent brain infarcts are detected by neuroimaging in up to 20% of asymptomatic patients based on population studies. They are five times more frequent than stroke in general population, and increase significantly both with advancing age and hypertension. Moreover, they are independently associated with the ...

journal_title：BMC neurology

authors： Riba-Llena I,Jarca CI,Mundet X,Tovar JL,Orfila F,López-Rueda A,Nafría C,Fernández JL,Castañé X,Domingo M,Alvarez-Sabín J,Fernández-Cortiñas I,Maisterra O,Montaner J,Delgado P

更新日期：2013-10-02 00:00:00