IncobotulinumtoxinA for the treatment of spasticity in children with cerebral palsy - a retrospective case series focusing on dosing and tolerability.

abstract：BACKGROUND:There is need for a cognitive test battery that can be easily used in clinical practice to detect or monitor cognitive performance in patients with multiple sclerosis (MS). In order to conduct, in this patient group, a preliminary investigation of the validity and utility of a brief computerized battery, the...

journal_title：BMC neurology

authors： Edgar C,Jongen PJ,Sanders E,Sindic C,Goffette S,Dupuis M,Jacquerye P,Guillaume D,Reznik R,Wesnes K

更新日期：2011-06-07 00:00:00

abstract：BACKGROUND:Migraine is a highly prevalent disorder. The disability provoked by its attacks results in suffering as well as considerable economic and social losses. The objective of migraine acute treatment is to restore the patient to normal function as quickly and consistently as possible. There are numerous drugs ava...

journal_title：BMC neurology

authors： Krymchantowski AV

更新日期：2004-01-28 00:00:00

abstract：BACKGROUND:Intracranial hemorrhage is a rare but potentially severe complication of spinal surgery. Most reported post-operative ICH cases consist of cerebellar hemorrhage. There are fewer reported cases of supratentorial ICH following spinal surgery. CASE PRESENTATION:A 56-year-old woman underwent spinal surgery comp...

journal_title：BMC neurology

authors： Berry B,Ghannam M,Bell C,Ghazaleh S,Boss S,Streib C,Ezzeddine M

更新日期：2018-12-14 00:00:00

abstract：BACKGROUND:Evidence indicates that the continuation of therapy among community-dwelling stroke survivors improves physical function. Community rehabilitation programmes often face limitations in terms of resources. It is imperative to include new motivational interventions to encourage some level of non-clinician manag...

journal_title：BMC neurology

authors： Singh DK,Mohd Nordin NA,Abd Aziz NA,Lim BK,Soh LC

更新日期：2013-12-13 00:00:00

abstract：BACKGROUND:B-mode and Color Doppler ultrasonography (CDUS) are the methods of choice for screening and determining the degree of Carotid artery stenosis. The evaluation of stenosis with calcification may be hampered by a common CDUS artifact known as acoustic shadow (AS). Our objective was to assess the change in relia...

journal_title：BMC neurology

authors： Seyman EE,Bornstein N,Auriel E,Cohen O,Nissel T,Hallevi H

更新日期：2019-07-29 00:00:00

abstract：BACKGROUND:Sub-cortical vascular ischaemia is the second most common etiology contributing to cognitive impairment in older adults, and is frequently under-diagnosed and under-treated. Although evidence is mounting that exercise has benefits for cognitive function among seniors, very few randomized controlled trials of...

journal_title：BMC neurology

authors： Liu-Ambrose T,Eng JJ,Boyd LA,Jacova C,Davis JC,Bryan S,Lee P,Brasher P,Hsiung GY

更新日期：2010-02-17 00:00:00

abstract：BACKGROUND:A few reliable national data concerning the etiology of non-traumatic spinal cord injury (SCI) in sub-Sahara Africa exists, mainly because of the limitations of diagnostic imaging. These are both expensive and mostly unavailable in several resource-limited settings. Only a few studies have employed the magne...

journal_title：BMC neurology

authors： Musubire AK,Meya DB,Katabira ET,Meyer ACL,Bohjanen PR,Boulware DR,Minja F

更新日期：2019-01-15 00:00:00

abstract：BACKGROUND:Detecting and treating neuropsychological deficits after aneurysmatic subarachnoid hemorrhage (aSAH) play a key role in regaining independence; however, detecting deficits relevant to social and professional reintegration has been difficult and optimal timing of assessments remains unclear. Therefore, we eva...

journal_title：BMC neurology

authors： Walter J,Grutza M,Vogt L,Unterberg A,Zweckberger K

更新日期：2020-11-26 00:00:00

abstract：BACKGROUND:Neurocysticercosis (NC) is one of the most frequent parasitic diseases of the central nervous system. Cysticidal drugs, albendazole and praziquantel, are generally effective when parasites localize in the parenchyma. In contrast, parasites lodged in the subarachnoid basal cisterns are less responsive to trea...

journal_title：BMC neurology

authors： Cárdenas G,Carrillo-Mezo R,Jung H,Sciutto E,Hernandez JL,Fleury A

更新日期：2010-03-04 00:00:00

abstract：BACKGROUND:Machado-Joseph disease (MJD), or spinocerebellar ataxia type 3 (SCA3), is an autosomal dominant neurodegenerative disorder of late onset, which is caused by a CAG repeat expansion in the coding region of the ATXN3 gene. This disease presents clinical heterogeneity, which cannot be completely explained by the...

journal_title：BMC neurology

authors： Bettencourt C,Santos C,Coutinho P,Rizzu P,Vasconcelos J,Kay T,Cymbron T,Raposo M,Heutink P,Lima M

更新日期：2011-10-24 00:00:00

abstract：BACKGROUND:Although the precise etiology of multiple sclerosis is largely unknown, there is some speculation that a prior history of surgery may be associated with the subsequent risk for developing the disease. Therefore, we aimed to examine surgery as a risk factor for the diagnosis of multiple sclerosis. METHODS:We...

journal_title：BMC neurology

authors： Lunny C,Knopp-Sihota JA,Fraser SN

更新日期：2013-05-06 00:00:00

abstract：BACKGROUND:Stroke survivors encounter emotional problems in the chronic phase after stroke. Post-stroke depressive symptoms have major impact on health-related quality of life (HRQol) and lead to increased hospitalization and therefore substantial healthcare costs. We present a cost-effectiveness and cost-utility evalu...

journal_title：BMC neurology

authors： van Eeden M,Kootker JA,Evers SM,van Heugten CM,Geurts AC,van Mastrigt GA

更新日期：2015-12-29 00:00:00

abstract：BACKGROUND:Active Rehabilitation (AR) is a community peer-based concept for people with spinal cord injury (SCI) that is primarily delivered through brief residential training programmes. Despite a plethora of positive anecdotal evidence of AR programmes as life-changing experiences, the effects of AR-programmes have n...

journal_title：BMC neurology

authors： Divanoglou A,Tasiemski T,Jörgensen S

更新日期：2020-01-11 00:00:00

abstract：BACKGROUND:Among patients with relapsing-remitting multiple sclerosis, relapses are associated with increased disability and decreased quality of life. Relapses are commonly treated with corticosteroids or left untreated. We aimed to better understand patient perceptions of the adequacy of corticosteroids in resolving ...

journal_title：BMC neurology

authors： Nickerson M,Marrie RA

更新日期：2013-09-10 00:00:00

abstract：BACKGROUND:Osteogenesis imperfecta (OI) is a heterogeneous group of inherited disorders that occur owing to the abnormalities in type 1 collagen, and is characterized by increased bone fragility and other extraskeletal manifestations. We report the case of a patient who was diagnosed with OI following subarachnoid hemo...

journal_title：BMC neurology

authors： Hirohata T,Miyawaki S,Mizutani A,Iwakami T,Yamada S,Nishido H,Suzuki Y,Miyamoto S,Hoya K,Murakami M,Matsuno A

更新日期：2014-07-23 00:00:00

abstract：BACKGROUND:Presently, for patients presenting with suspected Normal Pressure Hydrocephalus (NPH) who undergo temporary drainage of cerebrospinal fluid (CSF) there is no defined model to differentiate chance improvement form clinical significance change at the individual patient level. To address this lack of informatio...

journal_title：BMC neurology

authors： Davis A,Yasar S,Emerman I,Gulyani S,Khingelova K,Rao A,Manthripragada L,Luciano M,Moghekar A

更新日期：2020-04-16 00:00:00

abstract：BACKGROUND:Cerebral venous sinus thrombosis or stenosis (here collectively referred to as cerebral venous sinus occlusion, CVSO) can cause chronically-elevated intracranial pressure (ICP). Patients may have no neurological symptoms other than visual impairment, secondary to bilateral papilledema. Correctly recognizing ...

journal_title：BMC neurology

authors： Zhao T,Wang G,Dai J,Liu Y,Wang Y,Li S

更新日期：2018-09-29 00:00:00

abstract：BACKGROUND:Hemifacial spasm (HFS) is a disabling neurological condition. Vascular tortuosity in HFS patients has not been quantified objectively and its relationship with hypertension and posterior fossa volume (PF) is unknown. In a case control magnetic resonance imaging and angiographic (MRI/A) study, we quantified a...

journal_title：BMC neurology

authors： Edmond EC,Sim SX,Li HH,Tan EK,Chan LL

更新日期：2016-07-29 00:00:00

abstract：BACKGROUND:Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants for the treatment of depression in patients with Parkinson's Disease (PD) but data on their efficacy are controversial. METHODS:We conducted a systematic review and meta-analysis of randomized controlled trials ...

journal_title：BMC neurology

authors： Skapinakis P,Bakola E,Salanti G,Lewis G,Kyritsis AP,Mavreas V

更新日期：2010-06-21 00:00:00

abstract：BACKGROUND:To investigate the prognostic value of hyponatremia, defined as serum sodium level < 135 mEq/L, in radiation-induced brain necrosis (RN) patients. METHODS:We performed a retrospective analysis of the RN patients (The patients included in our study had a history of primary cancers including nasopharyngeal ca...

journal_title：BMC neurology

authors： Liao H,Zhu Z,Rong X,Wang H,Peng Y

更新日期：2018-08-29 00:00:00

abstract：BACKGROUND:MS-pathogenesis is known to involve both multiple environmental events, and several independent genetic risk-factors. METHODS:A model of susceptibility is developed and a mathematical analysis undertaken to elucidate the nature of genetic susceptibility to MS and to understand the constraints that are place...

journal_title：BMC neurology

authors： Goodin DS

更新日期：2010-10-28 00:00:00

abstract：BACKGROUND:The reliable and efficient measurement of spinal cord atrophy is of growing interest in monitoring disease progression in multiple sclerosis (MS). METHODS:We compared T1- and T2-weighted MRI for measuring cervical spinal cord volume in 31 patients with MS and 18 age-matched controls (NC) from T1-weighted gr...

journal_title：BMC neurology

authors： Kim G,Khalid F,Oommen VV,Tauhid S,Chu R,Horsfield MA,Healy BC,Bakshi R

更新日期：2015-07-31 00:00:00

abstract：BACKGROUND:The impact of comorbidity on multiple sclerosis (MS) is a new area of interest. Limited data on the risk factors of metabolic syndrome (MetS) is currently available. The aim of this study was to estimate the presence of comorbid conditions and MetS in a sample of adult patients with MS. METHODS:A retrospect...

journal_title：BMC neurology

authors： Sicras-Mainar A,Ruíz-Beato E,Navarro-Artieda R,Maurino J

更新日期：2017-07-17 00:00:00

abstract：:The advent of early absorption, distribution, metabolism, excretion, and toxicity (ADMET) screening has increased the attrition rate of weak drug candidates early in the drug-discovery process, and decreased the proportion of compounds failing in clinical trials for ADMET reasons. This paper reviews the history of ADM...

journal_title：BMC neurology

authors： Tsaioun K,Bottlaender M,Mabondzo A,Alzheimer's Drug Discovery Foundation.

更新日期：2009-06-12 00:00:00

abstract：BACKGROUND:Sarcoidosis is a multi-organ disease of unknown etiology characterised by the presence of epithelioid granulomas, without caseous necrosis. Systemic sarcoidosis is rare among children, while neurosarcoidosis in children is even rarer whether it is systemic or not. CASE PRESENTATION:We described the case of ...

journal_title：BMC neurology

authors： Shijo K,Moro N,Sasano M,Watanabe M,Yagasaki H,Takahashi S,Homma T,Yoshino A

更新日期：2018-05-29 00:00:00

abstract：BACKGROUND:Deep vein thrombosis (DVT) is an important complication of ischemic stroke, although the incidence of DVT is regarded as being lower in Asian than in non-Asian patients. Here, we investigated the incidence and factors associated with DVT in Asian patients with ischemic stroke. METHODS:Acute ischemic stroke ...

journal_title：BMC neurology

authors： Ha SH,Kim YJ,Heo SH,Chang DI,Kim BJ

更新日期：2020-06-27 00:00:00

abstract：BACKGROUND:Prediction of clinical outcome in the acute stage of ischaemic stroke can be difficult when based on patient characteristics, clinical findings and on non-contrast CT. CT perfusion and CT angiography may provide additional prognostic information and guide treatment in the early stage. We present the study pr...

journal_title：BMC neurology

authors： van Seeters T,Biessels GJ,van der Schaaf IC,Dankbaar JW,Horsch AD,Luitse MJ,Niesten JM,Mali WP,Kappelle LJ,van der Graaf Y,Velthuis BK,DUST investigators.

更新日期：2014-02-25 00:00:00

abstract：BACKGROUND:The autophagic vacuolar myopathies (AVM) are a group of inherited myopathies defined by the presence of autophagic vacuoles in pathological muscle specimens. AVM can be categorized into three groups: acid maltase deficiency, myopathies characterized by autophagic vacuoles with unique sarcolemmal features, an...

journal_title：BMC neurology

authors： Bokuda K,Sugaya K,Tamura S,Miyamoto K,Matsubara S,Komori T

更新日期：2012-11-21 00:00:00

abstract：BACKGROUND:Sturge-Weber syndrome (SWS) is a rare and sporadic congenital neurocutaneous disorder, that is characterized by facial venous capillary malformation (port-wine birthmark), leptomeningeal venous malformation (angiomatosis), glaucoma, and neurologic problems. SWS can comorbid with other disorders in some patie...

journal_title：BMC neurology

authors： Deng L,Wang D,Ruan N,Fu P

更新日期：2019-05-03 00:00:00

abstract：BACKGROUND:Chest pain as the primary manifestation of epilepsy is extremely rare and has only been reported once to date. CASE PRESENTATION:We herein describe a 47-year-old woman with recurrent chest pain for 3 years. The cause of her chest pain remained elusive despite extensive investigations including comprehensive...

journal_title：BMC neurology

authors： Khoo CS,Lee D,Park KM,In Lee B,Kim SE

更新日期：2019-12-30 00:00:00