Abstract:
BACKGROUND:B-mode and Color Doppler ultrasonography (CDUS) are the methods of choice for screening and determining the degree of Carotid artery stenosis. The evaluation of stenosis with calcification may be hampered by a common CDUS artifact known as acoustic shadow (AS). Our objective was to assess the change in reliability of CDUS readings in the presence of an AS artifact. METHODS:Single center retrospective observational study. Included were patients with either an AS artifact or high-grade stenosis (defined by peak systolic velocity (PSV) > 240 cm/s) demonstrated in CDUS, and had a CT angiography (CTA) done within 6 months of the sonographic exam. All subjects were identified through the Tel-Aviv Sorasky medical center (TASMC) CDUS unit registry from which clinical information was extracted. CDUS images were manually reviewed grading AS magnitude. All CTAs were reviewed and reconstructed for accurate assessment of percent stenosis and were used as gold standard. RESULTS:The study cohort included 227 consecutive patients (corresponding with 454 internal carotid arteries) meeting inclusion criteria. 43.2% of the arteries (n = 195) had an AS artifact present on CDUS, regardless of percent stenosis, with a large artifact present in 6.7% arteries (n = 30). Older age was significantly related to the presence of AS artifact (p < 0.001). In the study cohort as a whole there was a strong correlation between percent stenosis on CTA and PSV values (Pearson's r 0.672, p < 0.001) regardless of AS existence. The CDUS sensitivity and specificity for predicting severe stenosis were 82 and 73% respectively. The presence of a small AS slightly diminished the correlation between CDUS and CTA results without compromising CDUS reliability. A large AS severely affected the correlation between CDUS and CTA exams (Pearson's r = 0.24, p = 0.27) and reduced CDUS reliability with a sensitivity and specificity of 62%. CONCLUSION:The presence of a large AS severely degrades the accuracy of the routine CDUS measurements. In these cases, the patient should be referred to a CDUS exam including doppler-measurement of periorbital arteries and intracranial arteries in addition to other imaging modalities such as CTA or MRA in order to assess future stroke risk.
journal_name
BMC Neuroljournal_title
BMC neurologyauthors
Seyman EE,Bornstein N,Auriel E,Cohen O,Nissel T,Hallevi Hdoi
10.1186/s12883-019-1405-4subject
Has Abstractpub_date
2019-07-29 00:00:00pages
178issue
1issn
1471-2377pii
10.1186/s12883-019-1405-4journal_volume
19pub_type
杂志文章相关文献
BMC Neurology文献大全abstract:BACKGROUND:The etiologic determinants of stroke in young adults remain a diagnostic challenge in up to one-fourth of cases. Increasing evidences led to consider Fabry's disease (FD) as a possible cause to check up. We aimed at evaluating the prevalence of unrecognized FD in a cohort of patients with juvenile stroke in ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0513-z
更新日期:2015-12-12 00:00:00
abstract:BACKGROUND:Previous epidemiologic studies have examined the association of smoking with amyotrophic lateral sclerosis (ALS) incidence, but their results have been inconsistent. Moreover, limited information exists on the association between smoking and survival in ALS patients. We evaluated the association of smoking w...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-10-6
更新日期:2010-01-14 00:00:00
abstract:BACKGROUND:We imaged the corticospinal tract (CST) and corticoreticular pathway (CRP) using diffusion tensor tractography (DTT) to evaluate the cause of muscle weakness in a patient who was exposed to high-voltage electricity. CASE PRESENTATION:A 39-year-old man presented with quadriparesis after high-voltage electric...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-01707-2
更新日期:2020-04-13 00:00:00
abstract:BACKGROUND:Lumbo-sacral radiculopathy (LSR) is a common musculoskeletal disorder for which patients seek medical care and referrals for advanced imaging. However, accurate diagnosis remains challenging. Neuropathic pain screening questionnaires, clinical neurological examination and magnetic resonance imaging (MRI) are...
journal_title:BMC neurology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12883-019-1333-3
更新日期:2019-05-30 00:00:00
abstract:BACKGROUND:Migraine and Attention Deficit and Hyperactivity Disorder (ADHD) have been found to be associated in child and adolescent cohorts; however, the association has not been assessed in adults or otherwise healthy population. Assessing the comorbidity between ADHD and migraine may clarify the etiopathology of bot...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-018-1149-6
更新日期:2018-10-16 00:00:00
abstract:BACKGROUND:This study aimed to determine the risk of thromboembolic events in patients with junctional bradycardia(JB). METHODS:We retrospectively reviewed electrocardiograms(ECGs) for 380,682 patients. Those with JB on an ECG at least twice over a ≥3-month interval were included for analysis. We additionally included...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0645-9
更新日期:2016-07-25 00:00:00
abstract:BACKGROUND:Autosomal recessive cerebellar ataxias (ARCA) are a group of neurodegenerative disorders characterized by early onset of gait impairment, disturbed limb coordination, dysarthria, and eye movement abnormalities, most likely due to the degeneration of cerebellum, brainstem, and spinal cord. Despite of the rari...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0696-y
更新日期:2016-09-20 00:00:00
abstract:BACKGROUND:Gait ability and cognitive function are interrelated during both normal walking (NW) and dual-task walking (DTW), and gait ability is thus adversely affected by cognitive impairment in both situations. However, this association is insufficiently understood in people with mild cognitive impairment (MCI). Here...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-14-67
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Taste disorder is a common symptom in the general population. Several studies have shown that patients with neurological disorders, such as amyotrophic lateral sclerosis and Parkinson's disease, develop taste disturbance. Facial onset sensory and motor neuronopathy (FOSMN) is a rare disease characterized by ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-01639-x
更新日期:2020-02-29 00:00:00
abstract:BACKGROUND:Facioscapulohumeral muscular dystrophy (FSHD) is a dominantly-inherited progressive muscular dystrophy caused by de-repression of the DUX4 gene, which causes disease by a toxic-gain-of-function. As molecularly targeted drugs move from preclinical testing into human trials, it is essential that we validate cl...
journal_title:BMC neurology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12883-019-1452-x
更新日期:2019-09-10 00:00:00
abstract:BACKGROUND:High adherence to a Mediterranean Diet is associated with reduced incidence and mortality of acute ischemic stroke (AIS) but may also be associated with severity. Our purpose was to investigate the association of adherence to a Mediterranean diet and severity in a prospective hospital register of AIS patient...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-01824-y
更新日期:2020-06-23 00:00:00
abstract:BACKGROUND:Central sensitization is thought to be an important contributing factor in many chronic pain disorders. The Central Sensitization Inventory (CSI) is a patient-reported measure frequently used to assess symptoms related to central sensitization. The aims of the study were to translate and cross-culturally ada...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-01867-1
更新日期:2020-07-27 00:00:00
abstract:BACKGROUND:Elevated intracranial pressure from cerebral edema is the major cause of early mortality in acute stroke. Current treatment strategies to limit cerebral edema are not particularly effective. Some novel anti-edema measures have shown promising early findings in experimental stroke models. Vasopressin antagoni...
journal_title:BMC neurology
pub_type: 杂志文章,评审
doi:10.1186/s12883-014-0213-0
更新日期:2014-11-18 00:00:00
abstract:BACKGROUND:Cognitive disorders, such as memory disturbances, are often observed following a subarachnoid hemorrhage. We present a very rare case where rupture of a posterior cerebral artery aneurysm caused restricted damage to the hippocampus unilaterally, and caused memory disturbances. CASE PRESENTATION:A 56-year-ol...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-14-44
更新日期:2014-03-07 00:00:00
abstract:BACKGROUND:Heterogeneous disease trajectories of mild cognitive impairment (MCI) and dementia are frequently encountered in clinical practice, but there is still insufficient knowledge to understand the reasons and mechanisms causing this heterogeneity. In addition to correlates of the disorder, patient characteristics...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0750-9
更新日期:2016-11-25 00:00:00
abstract:BACKGROUND:Headache is a common complaint in children and adolescents. Recently, an increased prevalence of headache in children and adolescents has been reported. METHODS:We retrospectively reviewed the medical records of children and adolescents attending the Headache Clinic of Daejeon St. Mary's Hospital during the...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-018-1073-9
更新日期:2018-05-21 00:00:00
abstract:BACKGROUND:Different studies have found diminished cardiac metaiodobenzylguanidine (MIBG) uptake in Lewy body (LB) related conditions (Parkinson's disease (PD) and Lewy body dementia (LBD)). However, delayed heart/mediastinum (d-H/M) ratio diagnostic cutoff points are debated in parkinsonian syndromes. METHODS:We perf...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0338-9
更新日期:2015-05-15 00:00:00
abstract:BACKGROUND:Despite substantial research into the topic and valiant surgical efforts, reconstruction of peripheral nerve injury remains a challenging surgery. This study was conducted to evaluate the effectiveness of axonal regeneration of a transected sciatic nerve through a vein conduit containing degenerated skeletal...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0768-z
更新日期:2016-11-22 00:00:00
abstract:BACKGROUND:Hemifacial spasm (HFS) is a disabling neurological condition. Vascular tortuosity in HFS patients has not been quantified objectively and its relationship with hypertension and posterior fossa volume (PF) is unknown. In a case control magnetic resonance imaging and angiographic (MRI/A) study, we quantified a...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0634-z
更新日期:2016-07-29 00:00:00
abstract:BACKGROUND:Effective control of (upright) body posture requires a proper representation of body orientation. Stroke patients with pusher syndrome were shown to suffer from severely disturbed perception of own body orientation. They experience their body as oriented 'upright' when actually tilted by nearly 20 degrees to...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-6-30
更新日期:2006-08-23 00:00:00
abstract:BACKGROUND:Anterior spinal cord herniation (aSCH) is a rare cause of myelopathy which may present as pure motor syndrome and mimic other degenerative diseases of the spinal cord. In slowly progressive cases, diagnosis may be impeded by equivocal imaging results and mistaken for evolving upper motor neuron disease. As e...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-01891-1
更新日期:2020-08-29 00:00:00
abstract:BACKGROUND:Interleukin 36 (IL-36) cytokines belong to the IL-1 family and play an important role in some autoimmune diseases. However, the relationship between IL-36 and neuromyelitis optica spectrum disorders (NMOSD) remains unclear. METHODS:We determined serum IL-36α, IL-36β and IL-36γ levels and assessed correlatio...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-019-1415-2
更新日期:2019-08-05 00:00:00
abstract:BACKGROUND:Few studies on whether etiologic subtype can predict outcome in mild stroke are available. The study aim to explore the effect of different etiologic subtype on prognosis of these patients. METHODS:We prospectively registered consecutive cases of acute ischemic stroke from September. 01, 2009 to August. 31,...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-13-154
更新日期:2013-10-24 00:00:00
abstract:BACKGROUND:Rett syndrome (RTT) is a severe neurodevelopmental disorder mainly affecting females. One of the main clinical manifestations is hand stereotypies, which is presumed to based on dysfunction rather than on structural impairment. Reflex interictal discharge precipitated by tapping-lips in electroencephalogram ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-019-1296-4
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a clinically heterogeneous disorder characterized by epileptic seizures, psychosis, dyskinesia, consciousness impairments, and autonomic instability. Symptoms are always various. Sometimes it presents in milder or incomplete forms. We report 4 cases ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0787-9
更新日期:2017-01-05 00:00:00
abstract:BACKGROUND:Several environmental exposures, including infection with Epstein-Barr virus, low levels of vitamin D and smoking are established risk factors for multiple sclerosis (MS). Also, high hygienic standard and infection with parasites have been proposed to influence MS risk. The aim of this study was to investiga...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-014-0196-x
更新日期:2014-10-03 00:00:00
abstract:BACKGROUND:Post-translational modifications (PTMs) generate a tremendous protein diversity from the ~ 20,000 protein-coding genes of the human genome. In chronic pain conditions, exposure to pathological processes in the central nervous system could lead to disease-specific PTMs detectable in the cerebrospinal fluid (C...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-018-1116-2
更新日期:2018-08-16 00:00:00
abstract:BACKGROUND:Guillain-Barré syndrome (GBS) is an autoimmune condition characterized by peripheral neuropathy. The pathogenesis of GBS is not fully understood, and the mechanism of how intravenous immunoglobulin (IVIG) cures GBS is ambiguous. Herein, we investigated lymphocyte subsets in patients with two major subtypes o...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-014-0202-3
更新日期:2014-10-15 00:00:00
abstract:BACKGROUND:The aim of this study was to assess the diagnostic accuracy (sensitivity and specificity) of clinical, imaging and motor evoked potentials (MEP) for predicting the short-term prognosis of multiple sclerosis (MS). METHODS:We obtained clinical data, MRI and MEP from a prospective cohort of 51 patients and 20 ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-11-67
更新日期:2011-06-07 00:00:00
abstract:BACKGROUND:Our objective was to find which additional factors can influence the favorable result in stroke patients after receiving fibrinolytic and/or endovascular treatment, quantified as a more than 30% improvement of the NIHSS score at 7 days. METHODS:This is a retrospective study to find factors that could influe...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-01990-z
更新日期:2020-11-14 00:00:00