Increased serum IL-36β and IL-36γ levels in patients with neuromyelitis optica spectrum disorders: association with disease activity.

abstract：BACKGROUND:The two human cerebral hemispheres are continuously interacting, through excitatory and inhibitory influences and one critical structure subserving this interhemispheric balance is the corpus callosum. Interhemispheric neurophysiological abnormalities and intrahemispheric behavioral impairments have been rep...

journal_title：BMC neurology

authors： Fecteau S,Lassonde M,Théoret H

更新日期：2006-06-21 00:00:00

abstract：BACKGROUND:This study aimed to determine the risk of thromboembolic events in patients with junctional bradycardia(JB). METHODS:We retrospectively reviewed electrocardiograms(ECGs) for 380,682 patients. Those with JB on an ECG at least twice over a ≥3-month interval were included for analysis. We additionally included...

journal_title：BMC neurology

authors： Kim GS,Uhm JS,Kim TH,Lee H,Park J,Park JK,Joung B,Pak HN,Lee MH

更新日期：2016-07-25 00:00:00

abstract：BACKGROUND:Chronic fatigue syndrome (CFS) is a disabling condition that affects approximately 800,000 adult Americans. The pathophysiology remains unknown and there are no diagnostic markers or characteristic physical signs or laboratory abnormalities. Most CFS patients complain of unrefreshing sleep and many of the po...

journal_title：BMC neurology

authors： Unger ER,Nisenbaum R,Moldofsky H,Cesta A,Sammut C,Reyes M,Reeves WC

更新日期：2004-04-19 00:00:00

abstract：BACKGROUND:Epigenetics underlying refractory epilepsy is poorly understood. DNA methylation may affect gene expression in epilepsy patients without affecting DNA sequences. Herein, we investigated the association between Carbamazepine-resistant (CBZ-resistant) epilepsy and EPHX1 methylation in a northern Han Chinese po...

journal_title：BMC neurology

authors： Lv Y,Zheng X,Shi M,Wang Z,Cui L

更新日期：2019-06-04 00:00:00

abstract：BACKGROUND:Primary microcephaly is defined as reduced occipital-frontal circumference noticeable before 36 weeks of gestation. Large amount of insults might lead to microcephaly including infections, hypoxia and genetic mutations. More than 16 genes are described in autosomal recessive primary microcephaly. However, th...

journal_title：BMC neurology

authors： Picher-Martel V,Labrie Y,Rivest S,Lace B,Chrestian N

更新日期：2020-02-15 00:00:00

abstract：BACKGROUND:We imaged the corticospinal tract (CST) and corticoreticular pathway (CRP) using diffusion tensor tractography (DTT) to evaluate the cause of muscle weakness in a patient who was exposed to high-voltage electricity. CASE PRESENTATION:A 39-year-old man presented with quadriparesis after high-voltage electric...

journal_title：BMC neurology

authors： Boudier-Revéret M,Hsiao MY,Shyu SG,Chang MC

更新日期：2020-04-13 00:00:00

abstract：BACKGROUND:In order to evaluate the impact of cilostazol on endothelial function, we compared the changes of flow-mediated dilation (FMD) between aspirin and cilostazol groups in patients with acute cerebral ischemia. METHODS:Patients presenting with acute cerebral ischemic events were randomly assigned into aspirin (...

journal_title：BMC neurology

authors： Lee SJ,Lee JS,Choi MH,Lee SE,Shin DH,Hong JM

更新日期：2017-08-29 00:00:00

abstract：BACKGROUND:Assessment of subjective quality of life (QOL) of persons with multiple sclerosis (MS) could facilitate the detection of psychosocial aspects of disease that may otherwise go unrecognized. The objectives of the study were to (i) compare the QOL ratings of relapsing remitting (RRMS) and progressive (PMS) type...

journal_title：BMC neurology

authors： Alshubaili AF,Awadalla AW,Ohaeri JU,Mabrouk AA

更新日期：2007-09-18 00:00:00

abstract：BACKGROUND:The time from injury to surgery (TIS) is critical in the functional recovery of individuals with traumatic acute subdural hematoma (TASDH). However, only few studies have confirmed such notion. METHODS:The data of TASDH patients who were surgically treated in Chia-Yi Christian Hospital between January 2008 ...

journal_title：BMC neurology

authors： Chen SH,Sun JM,Fang WK

更新日期：2020-06-04 00:00:00

abstract：BACKGROUND:Despite substantial research into the topic and valiant surgical efforts, reconstruction of peripheral nerve injury remains a challenging surgery. This study was conducted to evaluate the effectiveness of axonal regeneration of a transected sciatic nerve through a vein conduit containing degenerated skeletal...

journal_title：BMC neurology

authors： Mohammadi J,Delaviz H,Mohammadi B,Delaviz H,Rad P

更新日期：2016-11-22 00:00:00

abstract：BACKGROUND:Different studies have found diminished cardiac metaiodobenzylguanidine (MIBG) uptake in Lewy body (LB) related conditions (Parkinson's disease (PD) and Lewy body dementia (LBD)). However, delayed heart/mediastinum (d-H/M) ratio diagnostic cutoff points are debated in parkinsonian syndromes. METHODS:We perf...

journal_title：BMC neurology

authors： Lamotte G,Morello R,Lebasnier A,Agostini D,Defer GL

更新日期：2015-05-15 00:00:00

abstract：BACKGROUND:Hemifacial spasm (HFS) is a disabling neurological condition. Vascular tortuosity in HFS patients has not been quantified objectively and its relationship with hypertension and posterior fossa volume (PF) is unknown. In a case control magnetic resonance imaging and angiographic (MRI/A) study, we quantified a...

journal_title：BMC neurology

authors： Edmond EC,Sim SX,Li HH,Tan EK,Chan LL

更新日期：2016-07-29 00:00:00

abstract：BACKGROUND:Economic costs related to treatment of multiple sclerosis (MS) must be justified by health state, quality of life (QOL) and social participation improvement. This study aims to describe correlations between social participation, economic costs, utility and MS-specific QOL in a sample of patients with MS (pwM...

journal_title：BMC neurology

authors： Kwiatkowski A,Marissal JP,Pouyfaucon M,Vermersch P,Hautecoeur P,Dervaux B

更新日期：2014-05-27 00:00:00

abstract：BACKGROUND:To evaluate the relationship between the flow signal intensity of branch arteries distal to the stenosis on 3-dimensional (3D) time-of-flight (TOF) magnetic resonance angiography (MRA) and the risk of stroke recurrence in patients with severe middle cerebral artery (MCA) trunk stenosis. METHODS:We prospecti...

journal_title：BMC neurology

authors： Chen H,Li Z,Hong H,Xing S,Liu G,Zhang A,Tan S,Zhang J,Zeng J

更新日期：2015-09-16 00:00:00

abstract：BACKGROUND:Rett syndrome (RTT) is a severe neurodevelopmental disorder mainly affecting females. One of the main clinical manifestations is hand stereotypies, which is presumed to based on dysfunction rather than on structural impairment. Reflex interictal discharge precipitated by tapping-lips in electroencephalogram ...

journal_title：BMC neurology

authors： Luo X,Li C,Wang X,Yu X,Jiang J

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Adrenomyeloneuropathy (AMN) is one of several phenotypes of the adrenoleukodystrophy spectrum caused by mutations in the ABCD1 gene on the X chromosome. An inflammatory component is part of the disease complex ranging from severe childhood CNS demyelination to spinal cord and peripheral nerve degeneration. ...

journal_title：BMC neurology

authors： Jønch AE,Danielsen ER,Thomsen C,Meden P,Svenstrup K,Nielsen JE

更新日期：2012-09-26 00:00:00

abstract：BACKGROUND:There is need for a cognitive test battery that can be easily used in clinical practice to detect or monitor cognitive performance in patients with multiple sclerosis (MS). In order to conduct, in this patient group, a preliminary investigation of the validity and utility of a brief computerized battery, the...

journal_title：BMC neurology

authors： Edgar C,Jongen PJ,Sanders E,Sindic C,Goffette S,Dupuis M,Jacquerye P,Guillaume D,Reznik R,Wesnes K

更新日期：2011-06-07 00:00:00

abstract：:In clinical neurology, a comprehensive understanding of consciousness has been regarded as an abstract concept--best left to philosophers. However, times are changing and the need to clinically assess consciousness is increasingly becoming a real-world, practical challenge. Current methods for evaluating altered level...

journal_title：BMC neurology

authors： Gawryluk JR,D'Arcy RC,Connolly JF,Weaver DF

更新日期：2010-01-29 00:00:00

abstract：BACKGROUND:Young ischemic stroke patients are common while classification and analysis based upon imaging characteristics are rarely reported. We intend to compare the clinical and MRI characteristics of cerebral stroke induced by intracranial atherosclerosis between young patients with branch occlusive disease (BOD) a...

journal_title：BMC neurology

authors： Zhao ZN,Li XL,Liu JZ,Jiang ZM,Wang AH

更新日期：2018-06-20 00:00:00

abstract：BACKGROUND:In Asia, stroke incidence varies dramatically from country to country. Little is known about stroke incidence in Asians/Pacific Islanders in the US, where regional heterogeneity in Asian/Pacific Islander sub-populations is great. We sought to characterize both the national and regional incidences of first an...

journal_title：BMC neurology

authors： Nguyen-Huynh MN,Johnston SC

更新日期：2005-11-10 00:00:00

abstract：BACKGROUND:Anterior spinal cord herniation (aSCH) is a rare cause of myelopathy which may present as pure motor syndrome and mimic other degenerative diseases of the spinal cord. In slowly progressive cases, diagnosis may be impeded by equivocal imaging results and mistaken for evolving upper motor neuron disease. As e...

journal_title：BMC neurology

authors： Regensburger M,Schlachetzki JCM,Klekamp J,Doerfler A,Winkler J

更新日期：2020-08-29 00:00:00

abstract：BACKGROUND:Inflammatory reactions occurring in the brain after ischemia may contribute to secondary damage. In the present study, effects of minocycline, an anti-inflammatory agent, alone or in combination with mild hypothermia on focal embolic cerebral ischemia have been examined. METHODS:Focal ischemic injury was in...

journal_title：BMC neurology

authors： Wang CX,Yang T,Noor R,Shuaib A

更新日期：2002-04-18 00:00:00

abstract：BACKGROUND:Spastic paraplegia, optic atrophy and neuropathy (Spoan syndrome) is an autosomal recessive disease with approximately 70 cases recorded in Brazil and Egypt. METHODS:This is a prospective longitudinal study performed with 47 patients affected with Spoan syndrome of seven communities of Rio Grande do Norte (...

journal_title：BMC neurology

authors： Galvão CRC,Cavalcante PMA,Olinda R,Graciani Z,Zatz M,Kok F,Santos S,Lancman S

更新日期：2019-10-27 00:00:00

abstract：BACKGROUND:Robotic devices are expected to be widely used in various applications including support for the independent mobility of the elderly with muscle weakness and people with impaired motor function as well as support for nursing care that involves heavy laborious work. We evaluated the effects of a hybrid assist...

journal_title：BMC neurology

authors： Maeshima S,Osawa A,Nishio D,Hirano Y,Takeda K,Kigawa H,Sankai Y

更新日期：2011-09-27 00:00:00

abstract：BACKGROUND:Non-ataxic symptoms of spinocerebellar ataxias (SCAs) vary widely and often overlap with various types of SCAs. Duration and severity of the disease and genetic background may play a role in such phenotypic diversity. We conducted the study in order to study clinical characteristics of common SCAs in Thailan...

journal_title：BMC neurology

authors： Boonkongchuen P,Pongpakdee S,Jindahra P,Papsing C,Peerapatmongkol P,Wetchaphanphesat S,Paiboonpol S,Dejthevaporn C,Tanprawate S,Nudsasarn A,Jariengprasert C,Muntham D,Ingsathit A,Pulkes T

更新日期：2014-04-05 00:00:00

abstract：BACKGROUND:Many migraineurs who seek care in headache clinics are refractory to treatment, despite advances in headache therapies. Epidemiology is poorly characterized, because diagnostic criteria for refractory migraine were not available until recently. We aimed to determine the frequency of refractory migraine in pa...

journal_title：BMC neurology

authors： Irimia P,Palma JA,Fernandez-Torron R,Martinez-Vila E

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Dementia has been associated with an increased risk of hip fracture. However, little research has been conducted on the impact of dementia on wrist or vertebral fracture development. The aim of this study was to investigate whether dementia is a risk factor for different types of fracture in Taiwan. METHODS...

journal_title：BMC neurology

authors： Wang HK,Hung CM,Lin SH,Tai YC,Lu K,Liliang PC,Lin CW,Lee YC,Fang PH,Chang LC,Li YC

更新日期：2014-09-12 00:00:00

abstract：BACKGROUND:The stability of hypoperfused brain tissue in stroke patients with major artery occlusions is unknown. The purpose of this study was to determine the persistence of a diffusion/perfusion mismatch in patients with ICA or proximal MCA occlusions. METHODS:Fourteen patients with ICA and/or proximal MCA occlusio...

journal_title：BMC neurology

authors： González RG,Hakimelahi R,Schaefer PW,Roccatagliata L,Sorensen AG,Singhal AB

更新日期：2010-02-10 00:00:00

abstract：BACKGROUND:Patients often report neurocognitive difficulties after neuroborreliosis (NB). The frequency and extent of cognitive problems in European patients have been studied incompletely. METHODS:Sixty patients received a neurological and neuropsychological work-up 6 months or longer after treatment for proven NB. Q...

journal_title：BMC neurology

authors： Schmidt H,Djukic M,Jung K,Holzgraefe M,Dechent P,von Steinbüchel N,Blocher J,Eiffert H,Schmidt-Samoa C

更新日期：2015-08-19 00:00:00

abstract：BACKGROUND:The clinical impact of neutralizing antibodies against interferon-beta (NAb) is controversial. Their presence can lead to a decrease in interferon-beta (IFNβ) efficacy. Fatigue reported in patients with multiple sclerosis (MS) may be associated with an unfavorable clinical course. We conducted a prospective ...

journal_title：BMC neurology

authors： Manceau P,Latarche C,Pittion S,Edan G,de Sèze J,Massart C,Debouverie M

更新日期：2014-11-30 00:00:00