Social participation in patients with multiple sclerosis: correlations between disability and economic burden.

abstract：BACKGROUND:A few reliable national data concerning the etiology of non-traumatic spinal cord injury (SCI) in sub-Sahara Africa exists, mainly because of the limitations of diagnostic imaging. These are both expensive and mostly unavailable in several resource-limited settings. Only a few studies have employed the magne...

journal_title：BMC neurology

authors： Musubire AK,Meya DB,Katabira ET,Meyer ACL,Bohjanen PR,Boulware DR,Minja F

更新日期：2019-01-15 00:00:00

abstract：BACKGROUND:Intracranial hemorrhage is a rare but potentially severe complication of spinal surgery. Most reported post-operative ICH cases consist of cerebellar hemorrhage. There are fewer reported cases of supratentorial ICH following spinal surgery. CASE PRESENTATION:A 56-year-old woman underwent spinal surgery comp...

journal_title：BMC neurology

authors： Berry B,Ghannam M,Bell C,Ghazaleh S,Boss S,Streib C,Ezzeddine M

更新日期：2018-12-14 00:00:00

abstract：BACKGROUND:Cannabis therapy has been considered an effective treatment for spasticity, although clinical reports of symptom reduction in multiple sclerosis (MS) describe mixed outcomes. Recently introduced therapies of combined Delta9-tetrahydrocannabinol (THC) and cannabidiol (CBD) extracts have potential for symptom ...

journal_title：BMC neurology

authors： Lakhan SE,Rowland M

更新日期：2009-12-04 00:00:00

abstract：BACKGROUND:The genetic epidemiology of ischemic stroke remains relatively unstudied, and information about the genetic epidemiology of ischemic stroke in populations with significant minority representation is currently unavailable. METHODS:The Brain Attack Surveillance in Corpus Christi project (BASIC) is a populatio...

journal_title：BMC neurology

authors： Lisabeth LD,Smith MA,Brown DL,Uchino K,Morgenstern LB

更新日期：2005-10-31 00:00:00

abstract：BACKGROUND:Acute seizures are a common cause of paediatric admissions to hospitals in Africa, and malaria is an important cause of seizures in endemic areas. Malaria has declined in the past decade whilst neonatal admissions have increased, both which may affect the incidence and phenotypes of acute seizures in African...

journal_title：BMC neurology

authors： Serem GK,Newton CR,Kariuki SM

更新日期：2015-10-06 00:00:00

abstract：BACKGROUND:Human serum paraoxonase 1 (PON1) plays a major role in the metabolism of several organophosphorus compounds. The enzyme is encoded by the polymorphic gene PON1, located on chromosome 7q21.3. Aiming to identify genetic variations related to the risk of developing brain tumors, we investigated the putative ass...

journal_title：BMC neurology

authors： Martínez C,Molina JA,Alonso-Navarro H,Jiménez-Jiménez FJ,Agúndez JA,García-Martín E

更新日期：2010-08-19 00:00:00

abstract：BACKGROUND:Chronic low back pain (CLBP) has been shown to be associated with various pathophysiological changes at several level of the sensorimotor system, pointing to a general hypersensitivity in CLBP patients. The aim of the present study was to investigate signs of generalized mechanical pain hypersensitivity in C...

journal_title：BMC neurology

authors： Puta C,Schulz B,Schoeler S,Magerl W,Gabriel B,Gabriel HH,Miltner WH,Weiss T

更新日期：2012-09-21 00:00:00

abstract：BACKGROUND:Several studies suggest that perceived psychosocial stress is associated with increased risk of stroke; however results are inconsistent with regard to definitions and measurement of perceived stress, features of individual study design, study conduct and conclusions drawn and no meta-analysis has yet been p...

journal_title：BMC neurology

authors： Booth J,Connelly L,Lawrence M,Chalmers C,Joice S,Becker C,Dougall N

更新日期：2015-11-12 00:00:00

abstract：BACKGROUND:Primary microcephaly is defined as reduced occipital-frontal circumference noticeable before 36 weeks of gestation. Large amount of insults might lead to microcephaly including infections, hypoxia and genetic mutations. More than 16 genes are described in autosomal recessive primary microcephaly. However, th...

journal_title：BMC neurology

authors： Picher-Martel V,Labrie Y,Rivest S,Lace B,Chrestian N

更新日期：2020-02-15 00:00:00

abstract：BACKGROUND:Epigenetics underlying refractory epilepsy is poorly understood. DNA methylation may affect gene expression in epilepsy patients without affecting DNA sequences. Herein, we investigated the association between Carbamazepine-resistant (CBZ-resistant) epilepsy and EPHX1 methylation in a northern Han Chinese po...

journal_title：BMC neurology

authors： Lv Y,Zheng X,Shi M,Wang Z,Cui L

更新日期：2019-06-04 00:00:00

abstract：BACKGROUND:A fraction of patients with penetrating artery infarction (PAI) experience progressive motor deficit deterioration (PMD). We sought to investigate the role of high-sensitivity C-reactive protein (hs-CRP) at admission in predicting PMD. METHODS:From January 2015 to September 2018, consecutive patients with P...

journal_title：BMC neurology

authors： Gong P,Liu Y,Huang T,Chen W,Jiang T,Gong Y,Lu M,Wang M,Zhang Y,Zhang X,Deng Q,Zhou J

更新日期：2019-12-29 00:00:00

abstract：BACKGROUND:There is much discourse in healthcare about the importance of client-centred rehabilitation, however in the realm of community-based therapy post-stroke there has been little investigation into the efficacy of goal-directed practice that reflects patients' valued activities. In addition, the effect of active...

journal_title：BMC neurology

authors： Graven C,Brock K,Hill K,Ames D,Cotton S,Joubert L

更新日期：2011-06-18 00:00:00

abstract：BACKGROUND:Seizures are one of the most important neurologic complications of human immuno-deficiency virus (HIV)-negative cryptococcal meningitis. A better understanding of the risk associated factors can help predict those who will require treatment. METHODS:This 22-year retrospective study enrolled 180 patients. Pr...

journal_title：BMC neurology

authors： Hung CW,Chang WN,Kung CT,Tsai NW,Wang HC,Lin WC,Huang CR,Huang CC,Tsai WC,Chang HW,Su YJ,Lin YJ,Cheng BC,Chang YT,Su CM,Lu CH

更新日期：2014-10-13 00:00:00

abstract：BACKGROUND:Stroke survivors encounter emotional problems in the chronic phase after stroke. Post-stroke depressive symptoms have major impact on health-related quality of life (HRQol) and lead to increased hospitalization and therefore substantial healthcare costs. We present a cost-effectiveness and cost-utility evalu...

journal_title：BMC neurology

authors： van Eeden M,Kootker JA,Evers SM,van Heugten CM,Geurts AC,van Mastrigt GA

更新日期：2015-12-29 00:00:00

abstract：BACKGROUND:Almost 40% of stroke patients have a poor outcome at 3 months after the index event. Predictors for stroke outcome in the early acute phase may help to tailor stroke treatment. Infection and inflammation are considered to influence stroke outcome. METHODS:In a prospective multicenter study in Germany and Sp...

journal_title：BMC neurology

authors： Mengel A,Ulm L,Hotter B,Harms H,Piper SK,Grittner U,Montaner J,Meisel C,Meisel A,Hoffmann S

更新日期：2019-07-03 00:00:00

abstract：BACKGROUND:Post-translational modifications (PTMs) generate a tremendous protein diversity from the ~ 20,000 protein-coding genes of the human genome. In chronic pain conditions, exposure to pathological processes in the central nervous system could lead to disease-specific PTMs detectable in the cerebrospinal fluid (C...

journal_title：BMC neurology

authors： Bäckryd E,Edström S,Gerdle B,Ghafouri B

更新日期：2018-08-16 00:00:00

abstract：BACKGROUND:Limb Girdle Muscular Dystrophy (LGMD), caused by defective α-dystroglycan (α-DG) glycosylation, was recently associated with mutations in Isoprenoid synthase domain-containing (ISPD) and GDP-mannose pyrophosphorylase B (GMPPB) genes. The frequency of ISPD and GMPPB gene mutations in the LGMD population is un...

journal_title：BMC neurology

authors： Magri F,Colombo I,Del Bo R,Previtali S,Brusa R,Ciscato P,Scarlato M,Ronchi D,D'Angelo MG,Corti S,Moggio M,Bresolin N,Comi GP

更新日期：2015-09-24 00:00:00

abstract：BACKGROUND:Multiple pathogenic factors may contribute to the pathophysiology of Alzheimer's disease (AD). Peripheral blood markers have been used to assess biochemical changes associated with AD and mild cognitive impairment (MCI) and involved in their pathophysiology. METHODS:Plasma samples and clinical data were obt...

journal_title：BMC neurology

authors： Kim SM,Song J,Kim S,Han C,Park MH,Koh Y,Jo SA,Kim YY

更新日期：2011-05-12 00:00:00

abstract：BACKGROUND:Clinical trials are the hallmark of evidence-based medicine, but recruitment is often challenging, especially in stroke trials investigating patients not being able to give informed consent. In some nations, ethics committees will not approve of inclusion in a clinical study via consent of a legal representa...

journal_title：BMC neurology

authors： Hotter B,Ulm L,Hoffmann S,Katan M,Montaner J,Bustamante A,Meisel A

更新日期：2017-12-04 00:00:00

abstract：BACKGROUND:Mechanical thrombectomy was approved by NICE as a treatment for stroke in 2016. However, most of the evidence is from studies conducted during working hours. Only few centres in the UK perform thrombectomies out-of-hours. The Royal Stoke University Hospital (RSUH) has offered thrombectomies over 24 h (24/7) ...

journal_title：BMC neurology

authors： Weddell J,Parr E,Knight S,Muddegowda G,Natarajan I,Chembala J,Ferdinand P,Ahmad N,Pencz Z,Rana S,Warusevitane A,Jadun C,Nayak S,Hashim Z,Augustine A,Sim J,Roffe C

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Road traffic accidents are known to be the main cause of traumatic brain injury (TBI). TBI is also a leading cause of death and disability. This study, by means of the idiographic approach (single-case experimental designs using multiple-baseline designs), has examined whether methylphenidate (MPH - trade na...

journal_title：BMC neurology

authors： Al-Adawi S,Al-Naamani A,Jaju S,Al-Farsi YM,Dorvlo ASS,Al-Maashani A,Al-Adawi SSH,Moustafa AA,Al-Sibani N,Essa MM,Burke DT,Qoronfleh MW

更新日期：2020-03-19 00:00:00

abstract：BACKGROUND:Myasthenia gravis (MG), an autoimmune neuromuscular disorder, occurs owing to autoantibodies against acetylcholine receptors. MG symptoms can be triggered by various vaccines. Many studies have evaluated the safety and adverse events of the human papillomavirus (HPV) vaccine. Here, we present a life-threaten...

journal_title：BMC neurology

authors： Chung JY,Lee SJ,Shin BS,Kang HG

更新日期：2018-12-28 00:00:00

abstract：BACKGROUND:Muscular weakness in myasthenia gravis (MG) is commonly assessed using Quantitative Myasthenia Gravis Score (QMG). More objective and quantitative measures may complement the use of clinical scales and might detect subclinical affection of muscles. We hypothesized that muscular weakness in patients with MG c...

journal_title：BMC neurology

authors： Hoffmann S,Siedler J,Brandt AU,Piper SK,Kohler S,Sass C,Paul F,Reilmann R,Meisel A

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:Cardioembolic stroke (CES) due to atrial fibrillation (AF) is associated with high stroke mortality. Oral anticoagulation (OAC) reduces stroke mortality, however, the impact of OAC-administration during hospital stay post ischemic stroke on mortality is unclear. We determined whether the timing of OAC initia...

journal_title：BMC neurology

authors： Palm F,Kraus M,Safer A,Wolf J,Becher H,Grau AJ

更新日期：2014-10-08 00:00:00

abstract：BACKGROUND:To assess the feasibility of using automated capture of Electronic Medical Record (EMR) data to build predictive models for amyotrophic lateral sclerosis (ALS) outcomes. METHODS:We used an Informatics for Integrating Biology and the Bedside search discovery tool to identify and extract data from 354 ALS pat...

journal_title：BMC neurology

authors： Karanevich AG,Weisbrod LJ,Jawdat O,Barohn RJ,Gajewski BJ,He J,Statland JM

更新日期：2018-12-14 00:00:00

abstract：:An international expert consensus committee recently recommended a brief battery of tests for cognitive evaluation in multiple sclerosis. The Brief International Cognitive Assessment for MS (BICAMS) battery includes tests of mental processing speed and memory. Recognizing that resources for validation will vary intern...

journal_title：BMC neurology

authors： Benedict RH,Amato MP,Boringa J,Brochet B,Foley F,Fredrikson S,Hamalainen P,Hartung H,Krupp L,Penner I,Reder AT,Langdon D

更新日期：2012-07-16 00:00:00

abstract：BACKGROUND:Anticoagulation using vitamin K antagonists (VKAs) significantly reduces the risk of recurrent stroke in stroke patients with atrial fibrillation (AF) and is recommended by guidelines. METHODS:The German Competence NETwork on Atrial Fibrillation established a nationwide prospective registry including 9,574 ...

journal_title：BMC neurology

authors： Haeusler KG,Gerth A,Limbourg T,Tebbe U,Oeff M,Wegscheider K,Treszl A,Ravens U,Meinertz T,Kirchhof P,Breithardt G,Steinbeck G,Nabauer M,AFNET registry investigators.

更新日期：2015-08-05 00:00:00

abstract：BACKGROUND:Chest pain as the primary manifestation of epilepsy is extremely rare and has only been reported once to date. CASE PRESENTATION:We herein describe a 47-year-old woman with recurrent chest pain for 3 years. The cause of her chest pain remained elusive despite extensive investigations including comprehensive...

journal_title：BMC neurology

authors： Khoo CS,Lee D,Park KM,In Lee B,Kim SE

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND:Active Rehabilitation (AR) is a community peer-based concept for people with spinal cord injury (SCI) that is primarily delivered through brief residential training programmes. Despite a plethora of positive anecdotal evidence of AR programmes as life-changing experiences, the effects of AR-programmes have n...

journal_title：BMC neurology

authors： Divanoglou A,Tasiemski T,Jörgensen S

更新日期：2020-01-11 00:00:00

abstract：BACKGROUND:Spinal muscular atrophy (SMA) is an autosomal recessive disorder that affects the motoneurons of the spinal anterior horn, resulting in hypotonia and muscle weakness. The disease is caused by deletion or mutation in the telomeric copy of SMN gene (SMN1) and clinical severity is in part determined by the copy...

journal_title：BMC neurology

authors： Darbar IA,Plaggert PG,Resende MB,Zanoteli E,Reed UC

更新日期：2011-03-24 00:00:00