Predictors and long-term outcome of seizures in human immuno-deficiency virus (HIV)-negative cryptococcal meningitis.

abstract：BACKGROUND:The etiologic determinants of stroke in young adults remain a diagnostic challenge in up to one-fourth of cases. Increasing evidences led to consider Fabry's disease (FD) as a possible cause to check up. We aimed at evaluating the prevalence of unrecognized FD in a cohort of patients with juvenile stroke in ...

journal_title：BMC neurology

authors： Fancellu L,Borsini W,Romani I,Pirisi A,Deiana GA,Sechi E,Doneddu PE,Rassu AL,Demurtas R,Scarabotto A,Cassini P,Arbustini E,Sechi G

更新日期：2015-12-12 00:00:00

abstract：BACKGROUND:A fraction of patients with penetrating artery infarction (PAI) experience progressive motor deficit deterioration (PMD). We sought to investigate the role of high-sensitivity C-reactive protein (hs-CRP) at admission in predicting PMD. METHODS:From January 2015 to September 2018, consecutive patients with P...

journal_title：BMC neurology

authors： Gong P,Liu Y,Huang T,Chen W,Jiang T,Gong Y,Lu M,Wang M,Zhang Y,Zhang X,Deng Q,Zhou J

更新日期：2019-12-29 00:00:00

abstract：BACKGROUND:The AD etiology is yet not properly known. Interactions among environmental factors, multiple susceptibility genes and aging, contribute to AD. This study investigates the factors that play role in causing AD and how changes in cellular pathways contribute to AD. METHODS:PUBMED database, MEDLINE database an...

journal_title：BMC neurology

authors： Shafi O

更新日期：2016-11-22 00:00:00

abstract：BACKGROUND:This multicenter, double-blind, placebo-controlled study assessed the efficacy of rotigotine transdermal patch on apathy and motor symptoms in patients with Parkinson's disease (PD). METHODS:Patients with PD-associated apathy (Unified Parkinson's Disease Rating Scale [UPDRS] I item 4 [motivation] ≥2 and pat...

journal_title：BMC neurology

authors： Hauser RA,Slawek J,Barone P,Dohin E,Surmann E,Asgharnejad M,Bauer L

更新日期：2016-06-07 00:00:00

abstract：BACKGROUND:Recent consensus guidelines recommend pregabalin as a first-tier treatment for painful diabetic peripheral neuropathy (DPN). We evaluated the efficacy of pregabalin 600 mg/d (300 mg dosed BID) versus placebo for relieving DPN-associated neuropathic pain, and assessed its safety using objective measures of ne...

journal_title：BMC neurology

authors： Arezzo JC,Rosenstock J,Lamoreaux L,Pauer L

更新日期：2008-09-16 00:00:00

abstract：BACKGROUND:Recent exercise guidelines for people with multiple sclerosis (MS) recommend a minimum of 30 min moderate intensity aerobic exercise and resistance exercise twice per week. This trial compared the secondary outcomes of a combined 10-week guideline based intervention and a Social Cognitive Theory (SCT) educat...

journal_title：BMC neurology

authors： Coote S,Uszynski M,Herring MP,Hayes S,Scarrott C,Newell J,Gallagher S,Larkin A,Motl RW

更新日期：2017-06-24 00:00:00

abstract：BACKGROUND:Active Rehabilitation (AR) is a community peer-based concept for people with spinal cord injury (SCI) that is primarily delivered through brief residential training programmes. Despite a plethora of positive anecdotal evidence of AR programmes as life-changing experiences, the effects of AR-programmes have n...

journal_title：BMC neurology

authors： Divanoglou A,Tasiemski T,Jörgensen S

更新日期：2020-01-11 00:00:00

abstract：BACKGROUND:French Guiana has the highest incidence of ischemic and hemorrhagic stroke of all French territories. However, there is no further information on the epidemiology and management of stroke in French Guiana. Our goal was to describe the characteristics of patients in French Guiana in order to generate hypothes...

journal_title：BMC neurology

authors： Rochemont DR,Mimeau E,Misslin-Tritsch C,Papaix-Puech M,Delmas E,Bejot Y,DeToffol B,Fournel I,Nacher M

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:Myasthenia gravis (MG), an autoimmune neuromuscular disorder, occurs owing to autoantibodies against acetylcholine receptors. MG symptoms can be triggered by various vaccines. Many studies have evaluated the safety and adverse events of the human papillomavirus (HPV) vaccine. Here, we present a life-threaten...

journal_title：BMC neurology

authors： Chung JY,Lee SJ,Shin BS,Kang HG

更新日期：2018-12-28 00:00:00

abstract：BACKGROUND:Facioscapulohumeral muscular dystrophy (FSHD) is a dominantly-inherited progressive muscular dystrophy caused by de-repression of the DUX4 gene, which causes disease by a toxic-gain-of-function. As molecularly targeted drugs move from preclinical testing into human trials, it is essential that we validate cl...

journal_title：BMC neurology

authors： LoRusso S,Johnson NE,McDermott MP,Eichinger K,Butterfield RJ,Carraro E,Higgs K,Lewis L,Mul K,Sacconi S,Sansone VA,Shieh P,van Engelen B,Wagner K,Wang L,Statland JM,Tawil R,ReSolve Investigators and the FSHD CTRN18.

更新日期：2019-09-10 00:00:00

abstract：BACKGROUND:The WHOQOL-BREF is a frequently used instrument for the assessment of health-related quality of life. Unlike other generic instruments used for the assessment of this construct, little is known about its properties in individuals with headache disorders. The present study examines the reliability and factori...

journal_title：BMC neurology

authors： Brzoska P

更新日期：2020-07-03 00:00:00

abstract：BACKGROUND:Central sensitization is thought to be an important contributing factor in many chronic pain disorders. The Central Sensitization Inventory (CSI) is a patient-reported measure frequently used to assess symptoms related to central sensitization. The aims of the study were to translate and cross-culturally ada...

journal_title：BMC neurology

authors： Sharma S,Jha J,Pathak A,Neblett R

更新日期：2020-07-27 00:00:00

abstract：BACKGROUND:Anticoagulation using vitamin K antagonists (VKAs) significantly reduces the risk of recurrent stroke in stroke patients with atrial fibrillation (AF) and is recommended by guidelines. METHODS:The German Competence NETwork on Atrial Fibrillation established a nationwide prospective registry including 9,574 ...

journal_title：BMC neurology

authors： Haeusler KG,Gerth A,Limbourg T,Tebbe U,Oeff M,Wegscheider K,Treszl A,Ravens U,Meinertz T,Kirchhof P,Breithardt G,Steinbeck G,Nabauer M,AFNET registry investigators.

更新日期：2015-08-05 00:00:00

abstract：BACKGROUND:A number of emerging studies have evaluated clot composition in acute ischemic stroke. Studies of clot composition of embolic strokes of undetermined strokes are lacking. OBJECTIVES:We sought to analyze the RBC to platelet ratios in clots and correlated our findings with stroke etiology. METHODS:This was a...

journal_title：BMC neurology

authors： Nouh A,Mehta T,Hussain M,Song X,Ollenschleger M

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:Patients with ischemic cerebrovascular diseases are more likely to suffer from intracranial aneurysms, and their surgical treatment has a growing controversy in this condition. The current case series was aimed at exploring surgical treatment and perioperative management of intracranial aneurysms in Chinese ...

journal_title：BMC neurology

authors： Zheng Y,Wu C

更新日期：2018-09-14 00:00:00

abstract：BACKGROUND:Machado-Joseph disease (MJD), or spinocerebellar ataxia type 3 (SCA3), is an autosomal dominant neurodegenerative disorder of late onset, which is caused by a CAG repeat expansion in the coding region of the ATXN3 gene. This disease presents clinical heterogeneity, which cannot be completely explained by the...

journal_title：BMC neurology

authors： Bettencourt C,Santos C,Coutinho P,Rizzu P,Vasconcelos J,Kay T,Cymbron T,Raposo M,Heutink P,Lima M

更新日期：2011-10-24 00:00:00

abstract：BACKGROUND:Patients with acute stroke are particularly vulnerable to delirium episodes. Although delirium detection is important, no evidence-based recommendations have been established to date on how these patients should be routinely screened for delirium or which tool should be used for this purpose in this populati...

journal_title：BMC neurology

authors： Mansutti I,Saiani L,Palese A

更新日期：2019-12-02 00:00:00

abstract：BACKGROUND:The disease burden of human immunodeficiency virus (HIV)--acquired immunodeficiency syndrome (AIDS) is highest in sub-Saharan Africa but there are few studies on the associated neurocognitive disorders in this region. The objectives of this study were to determine whether Western neuropsychological (NP) meth...

journal_title：BMC neurology

authors： Kanmogne GD,Kuate CT,Cysique LA,Fonsah JY,Eta S,Doh R,Njamnshi DM,Nchindap E,Franklin DR Jr,Ellis RJ,McCutchan JA,Binam F,Mbanya D,Heaton RK,Njamnshi AK

更新日期：2010-07-13 00:00:00

abstract：BACKGROUND:This study aimed to investigate the prevalence and clinical relevance of chronic cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis (MS) patients and healthy controls using extra- and intracranial colour Doppler sonography. METHODS:We examined 146 MS patients, presenting with a clinically isol...

journal_title：BMC neurology

authors： Lanzillo R,Mancini M,Liuzzi R,Di Donato O,Salvatore E,Maglio V,Vacca G,Amato L,D'Anna G,Brunetti A,Brescia Morra V

更新日期：2013-02-13 00:00:00

abstract：BACKGROUND:Cerebral microvascular abnormality is frequently associated with lacunar and subcortical ischemic lesions. We performed acute and follow-up CT perfusion scans over the first 3 months after ischemic stroke to investigate disturbances of the blood-brain barrier (BBB) and cerebral perfusion in patients with lac...

journal_title：BMC neurology

authors： Yang J,d'Esterre C,Ceruti S,Roversi G,Saletti A,Fainardi E,Lee TY

更新日期：2015-10-22 00:00:00

abstract：BACKGROUND:Room tilt illusion (RTI) is a rare symptom of higher vestibular dysfunction, consisting of a transient vertical rotation of the visual scene in the sagittal or coronal plane, most often 90o or 180o, without any alteration in shape, size and color of objects. CASE PRESENTATION:A 63-year-old woman with a hist...

journal_title：BMC neurology

authors： Arntzen K,Alstadhaug KB

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:There is much discourse in healthcare about the importance of client-centred rehabilitation, however in the realm of community-based therapy post-stroke there has been little investigation into the efficacy of goal-directed practice that reflects patients' valued activities. In addition, the effect of active...

journal_title：BMC neurology

authors： Graven C,Brock K,Hill K,Ames D,Cotton S,Joubert L

更新日期：2011-06-18 00:00:00

abstract：BACKGROUND:Tinnitus is a result of hyper-activity/hyper-synchrony of auditory neurons coding the tinnitus frequency, which has developed to synchronous mass activity owing the lack of inhibition. We assume that removal of exactly these frequency components from an auditory stimulus will cause the brain to reorganize ar...

journal_title：BMC neurology

authors： Pantev C,Rudack C,Stein A,Wunderlich R,Engell A,Lau P,Wollbrink A,Shaykevich A

更新日期：2014-03-02 00:00:00

abstract：BACKGROUND:Assessment of subjective quality of life (QOL) of persons with multiple sclerosis (MS) could facilitate the detection of psychosocial aspects of disease that may otherwise go unrecognized. The objectives of the study were to (i) compare the QOL ratings of relapsing remitting (RRMS) and progressive (PMS) type...

journal_title：BMC neurology

authors： Alshubaili AF,Awadalla AW,Ohaeri JU,Mabrouk AA

更新日期：2007-09-18 00:00:00

abstract：BACKGROUND:Intracranial hemorrhage in central nervous system lymphoma is extremely rare. T2*-weighted gradient-echo magnetic resonance imaging is of particularly use in detecting silent hemorrhage as hypointense signals due to the deposition of paramagnetic hemosiderin or mineralization. Multifocal hemosiderin depositi...

journal_title：BMC neurology

authors： Yang XZ,Ni J,Cui LY

更新日期：2014-09-25 00:00:00

abstract：BACKGROUND:Complaints of unrefreshing sleep are a prominent component of chronic fatigue syndrome (CFS); yet, polysomnographic studies have not consistently documented sleep abnormalities in CFS patients. We conducted this study to determine whether alterations in objective sleep characteristics are associated with sub...

journal_title：BMC neurology

authors： Majer M,Jones JF,Unger ER,Youngblood LS,Decker MJ,Gurbaxani B,Heim C,Reeves WC

更新日期：2007-12-05 00:00:00

abstract：BACKGROUND:Tumor location served as an important prognostic factor in glioma patients was considered to postulate molecular features according to cell origin theory. However, anatomic distribution of unique molecular subtypes was not widely investigated. The relationship between molecular phenotype and histological sub...

journal_title：BMC neurology

authors： Tang Q,Lian Y,Yu J,Wang Y,Shi Z,Chen L

更新日期：2017-09-15 00:00:00

abstract：:The advent of early absorption, distribution, metabolism, excretion, and toxicity (ADMET) screening has increased the attrition rate of weak drug candidates early in the drug-discovery process, and decreased the proportion of compounds failing in clinical trials for ADMET reasons. This paper reviews the history of ADM...

journal_title：BMC neurology

authors： Tsaioun K,Bottlaender M,Mabondzo A,Alzheimer's Drug Discovery Foundation.

更新日期：2009-06-12 00:00:00

abstract：BACKGROUND:Epilepsy is a major complication of stroke. We aimed to establish whether there is an association between intravenous thrombolysis, intra-arterial thrombolysis and post stroke seizure (PSS) development. Improved understanding of the relationship between reperfusion therapies and seizure development may impro...

journal_title：BMC neurology

authors： Naylor J,Thevathasan A,Churilov L,Guo R,Xiong Y,Koome M,Chen Z,Chen Z,Liu X,Kwan P,Campbell BCV

更新日期：2018-05-03 00:00:00

abstract：BACKGROUND:Volume isotropic turbo spin-echo acquisition (VISTA) is a new method similar to the 3D black-blood imaging method that enables visualization of a intramural hematoma. T1-VISTA has recently been applied in the diagnosis of intracranial arterial dissection. However, the identification of an intramural hematoma...

journal_title：BMC neurology

authors： Ishitsuka K,Sakaki Y,Sakai S,Uwatoko T,Aibe H,Ago T,Kitazono T,Sugimori H

更新日期：2016-07-29 00:00:00