The association between high-sensitivity C-reactive protein at admission and progressive motor deficits in patients with penetrating artery infarctions.

abstract：BACKGROUND:Autosomal recessive cerebellar ataxias (ARCA) are a group of neurodegenerative disorders characterized by early onset of gait impairment, disturbed limb coordination, dysarthria, and eye movement abnormalities, most likely due to the degeneration of cerebellum, brainstem, and spinal cord. Despite of the rari...

journal_title：BMC neurology

authors： Lu C,Zheng YC,Dong Y,Li HF

更新日期：2016-09-20 00:00:00

abstract：BACKGROUND:Human cytomegalovirus (CMV) is an ubiquitous pathogen capable of modulating the host immune system. Immune dysfunction is common during CMV infection and includes autoimmune phenomena. Here we focus on a case of primary CMV infection associated with encephalopathy in a patient with a rudimentary spleen. We d...

journal_title：BMC neurology

authors： Xu X,Bergman P,Willows T,Tammik C,Sund M,Hökfelt T,Söderberg-Naucler C,Varani S

更新日期：2012-09-04 00:00:00

abstract：BACKGROUND:Periodic alternating ping-pong gaze (PPG) is a rare disease with few reports. To our knowledge, there was no report on anti GQ1b antibody syndrome accompanied by PPG. This paper reported a case of anti GQ1b antibody syndrome with Bickerstaff's Encephalitis (BBE) overlapping classic Guillain-Barre Syndrome (G...

journal_title：BMC neurology

authors： Han J,Xie Y,Yan H,Cao Y,HongmeiWang,Cao D

更新日期：2019-02-19 00:00:00

abstract：BACKGROUND:Clinical trials are the hallmark of evidence-based medicine, but recruitment is often challenging, especially in stroke trials investigating patients not being able to give informed consent. In some nations, ethics committees will not approve of inclusion in a clinical study via consent of a legal representa...

journal_title：BMC neurology

authors： Hotter B,Ulm L,Hoffmann S,Katan M,Montaner J,Bustamante A,Meisel A

更新日期：2017-12-04 00:00:00

abstract：BACKGROUND:Non-ataxic symptoms of spinocerebellar ataxias (SCAs) vary widely and often overlap with various types of SCAs. Duration and severity of the disease and genetic background may play a role in such phenotypic diversity. We conducted the study in order to study clinical characteristics of common SCAs in Thailan...

journal_title：BMC neurology

authors： Boonkongchuen P,Pongpakdee S,Jindahra P,Papsing C,Peerapatmongkol P,Wetchaphanphesat S,Paiboonpol S,Dejthevaporn C,Tanprawate S,Nudsasarn A,Jariengprasert C,Muntham D,Ingsathit A,Pulkes T

更新日期：2014-04-05 00:00:00

abstract：BACKGROUND:Different apoptosis pathways activate caspase-3. In a study involving 27 patients with traumatic brain injury (TBI), higher caspase-3 levels were found in contusion brain tissue resected from non-survivors than from survivors. The objective of this study was to determine whether there is an association in TB...

journal_title：BMC neurology

authors： Lorente L,Martín MM,Argueso M,Ramos L,Solé-Violán J,Riaño-Ruiz M,Jiménez A,Borreguero-León JM

更新日期：2015-11-06 00:00:00

abstract：BACKGROUND:Patients with Mild Cognitive Impairment (MCI) are at high risk of progression to Alzheimer's dementia. Identifying MCI individuals with high likelihood of conversion to dementia and the associated biosignatures has recently received increasing attention in AD research. Different biosignatures for AD (neuroim...

journal_title：BMC neurology

authors： Ye J,Farnum M,Yang E,Verbeeck R,Lobanov V,Raghavan N,Novak G,DiBernardo A,Narayan VA,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2012-06-25 00:00:00

abstract：BACKGROUND:Cognitive impairment commonly occurs in the acute phase post-stroke, but may persist with over half of all stroke survivors experiencing some form of long-term cognitive deficit. Recent evidence suggests that optimising secondary prevention adherence is a critical factor in preventing recurrent stroke and th...

journal_title：BMC neurology

authors： Mellon L,Brewer L,Hall P,Horgan F,Williams D,Hickey A,ASPIRE-S study group.

更新日期：2015-03-12 00:00:00

abstract：BACKGROUND:Falls frequency increases with age and particularly in neurogeriatric cohorts. The interplay between eye movements and locomotion may contribute substantially to the occurrence of falls, but is hardly investigated. This paper provides an overview of current approaches to simultaneously measure eye and body m...

journal_title：BMC neurology

authors： Srulijes K,Mack DJ,Klenk J,Schwickert L,Ihlen EA,Schwenk M,Lindemann U,Meyer M,Srijana KC,Hobert MA,Brockmann K,Wurster I,Pomper JK,Synofzik M,Schneider E,Ilg U,Berg D,Maetzler W,Becker C

更新日期：2015-10-09 00:00:00

abstract：BACKGROUND:The reliable and efficient measurement of spinal cord atrophy is of growing interest in monitoring disease progression in multiple sclerosis (MS). METHODS:We compared T1- and T2-weighted MRI for measuring cervical spinal cord volume in 31 patients with MS and 18 age-matched controls (NC) from T1-weighted gr...

journal_title：BMC neurology

authors： Kim G,Khalid F,Oommen VV,Tauhid S,Chu R,Horsfield MA,Healy BC,Bakshi R

更新日期：2015-07-31 00:00:00

abstract：BACKGROUND:The cognitive consequences of carbon monoxide (CO) poisoning are well described. However, most studies have been carried out without an ad-hoc group of control subjects. The main aim of this study was to evaluate cognitive and psychiatric outcome after CO exposure during the storm Klaus in the South West of ...

journal_title：BMC neurology

authors： Pages B,Planton M,Buys S,Lemesle B,Birmes P,Barbeau EJ,Maziero S,Cordier L,Cabot C,Puel M,Genestal M,Chollet F,Pariente J

更新日期：2014-07-21 00:00:00

abstract：BACKGROUND:French Guiana has the highest incidence of ischemic and hemorrhagic stroke of all French territories. However, there is no further information on the epidemiology and management of stroke in French Guiana. Our goal was to describe the characteristics of patients in French Guiana in order to generate hypothes...

journal_title：BMC neurology

authors： Rochemont DR,Mimeau E,Misslin-Tritsch C,Papaix-Puech M,Delmas E,Bejot Y,DeToffol B,Fournel I,Nacher M

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:Phase I/II placebo-controlled clinical trials of recombinant Factor VIIa (rFVIIa) suggested that administration of rFVIIa within 4 hours after onset of intracerebral hemorrhage (ICH) is safe, limits ICH growth, and improves outcomes. We sought to determine the cost-effectiveness of rFVIIa for acute ICH treat...

journal_title：BMC neurology

authors： Kissela BM,Eckman MH

更新日期：2008-05-19 00:00:00

abstract：BACKGROUND:Prediction of clinical outcome in the acute stage of ischaemic stroke can be difficult when based on patient characteristics, clinical findings and on non-contrast CT. CT perfusion and CT angiography may provide additional prognostic information and guide treatment in the early stage. We present the study pr...

journal_title：BMC neurology

authors： van Seeters T,Biessels GJ,van der Schaaf IC,Dankbaar JW,Horsch AD,Luitse MJ,Niesten JM,Mali WP,Kappelle LJ,van der Graaf Y,Velthuis BK,DUST investigators.

更新日期：2014-02-25 00:00:00

abstract：BACKGROUND:In the pathogenesis of limbic encephalitis other promoting factors besides the pure existence of autoantibodies are increasingly discussed to play a significant role. This is to our knowledge the first described patient in whom the presence of autoantibodies precedes the manifestation of limbic encephalitis ...

journal_title：BMC neurology

authors： Fauser S,Uttner I,Ariño H,Scherbaum WA,Saiz A,Lewerenz J

更新日期：2015-09-30 00:00:00

abstract：BACKGROUND:Muscular weakness in myasthenia gravis (MG) is commonly assessed using Quantitative Myasthenia Gravis Score (QMG). More objective and quantitative measures may complement the use of clinical scales and might detect subclinical affection of muscles. We hypothesized that muscular weakness in patients with MG c...

journal_title：BMC neurology

authors： Hoffmann S,Siedler J,Brandt AU,Piper SK,Kohler S,Sass C,Paul F,Reilmann R,Meisel A

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:The clinical features of Alzheimer's disease (AD) are related to brain network degeneration, and hyperhomocysteinemia is related to greater white matter hyperintensities. We investigated the changes in four diffusion tensor imaging parameters in the white matter of patients with early stage AD, examined thei...

journal_title：BMC neurology

authors： Lee CC,Hsu SW,Huang CW,Chang WN,Chen SF,Wu MK,Chang CC,Hwang LC,Chen PC

更新日期：2017-10-06 00:00:00

abstract：BACKGROUND:Migraine and Attention Deficit and Hyperactivity Disorder (ADHD) have been found to be associated in child and adolescent cohorts; however, the association has not been assessed in adults or otherwise healthy population. Assessing the comorbidity between ADHD and migraine may clarify the etiopathology of bot...

journal_title：BMC neurology

authors： Hansen TF,Hoeffding LK,Kogelman L,Haspang TM,Ullum H,Sørensen E,Erikstrup C,Pedersen OB,Nielsen KR,Hjalgrim H,Paarup HM,Werge T,Burgdorf K

更新日期：2018-10-16 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate and identify the risk factors for developing a new or enlarged intracranial hemorrhage (ICH) after the placement of an external ventricular drain. METHODS:A single center, nested case-control study of individuals who received an external ventricular drain from Jun...

journal_title：BMC neurology

authors： Rowe AS,Rinehart DR,Lezatte S,Langdon JR

更新日期：2018-03-07 00:00:00

abstract：BACKGROUND:Delayed post-hypoxic leukoencephalopathy (DPHL) is a demyelinating syndrome characterized by neurological relapse after an initial recovery from hypoxic brain injury. We describe a patient with impaired consciousness following DPHL, concurrent with injury of the ascending reticular activating system (ARAS) s...

journal_title：BMC neurology

authors： Jang SH,Kwon HG

更新日期：2017-07-19 00:00:00

abstract：BACKGROUND:The clinical impact of neutralizing antibodies against interferon-beta (NAb) is controversial. Their presence can lead to a decrease in interferon-beta (IFNβ) efficacy. Fatigue reported in patients with multiple sclerosis (MS) may be associated with an unfavorable clinical course. We conducted a prospective ...

journal_title：BMC neurology

authors： Manceau P,Latarche C,Pittion S,Edan G,de Sèze J,Massart C,Debouverie M

更新日期：2014-11-30 00:00:00

abstract：:An international expert consensus committee recently recommended a brief battery of tests for cognitive evaluation in multiple sclerosis. The Brief International Cognitive Assessment for MS (BICAMS) battery includes tests of mental processing speed and memory. Recognizing that resources for validation will vary intern...

journal_title：BMC neurology

authors： Benedict RH,Amato MP,Boringa J,Brochet B,Foley F,Fredrikson S,Hamalainen P,Hartung H,Krupp L,Penner I,Reder AT,Langdon D

更新日期：2012-07-16 00:00:00

abstract：BACKGROUND:Cerebral microvascular abnormality is frequently associated with lacunar and subcortical ischemic lesions. We performed acute and follow-up CT perfusion scans over the first 3 months after ischemic stroke to investigate disturbances of the blood-brain barrier (BBB) and cerebral perfusion in patients with lac...

journal_title：BMC neurology

authors： Yang J,d'Esterre C,Ceruti S,Roversi G,Saletti A,Fainardi E,Lee TY

更新日期：2015-10-22 00:00:00

abstract：BACKGROUND:Tumor location served as an important prognostic factor in glioma patients was considered to postulate molecular features according to cell origin theory. However, anatomic distribution of unique molecular subtypes was not widely investigated. The relationship between molecular phenotype and histological sub...

journal_title：BMC neurology

authors： Tang Q,Lian Y,Yu J,Wang Y,Shi Z,Chen L

更新日期：2017-09-15 00:00:00

abstract：BACKGROUND:Fatigue is a common complaint in multiple sclerosis (MS) and often interferes with daily functioning. Both clinicians and researchers may need to detect high levels of fatigue impact using a time and effort efficient tool. This study evaluates the psychometric properties of a rapid screening instrument for f...

journal_title：BMC neurology

authors： Kos D,Nagels G,D'Hooghe MB,Duportail M,Kerckhofs E

更新日期：2006-08-17 00:00:00

abstract：BACKGROUND:Sub-cortical vascular ischaemia is the second most common etiology contributing to cognitive impairment in older adults, and is frequently under-diagnosed and under-treated. Although evidence is mounting that exercise has benefits for cognitive function among seniors, very few randomized controlled trials of...

journal_title：BMC neurology

authors： Liu-Ambrose T,Eng JJ,Boyd LA,Jacova C,Davis JC,Bryan S,Lee P,Brasher P,Hsiung GY

更新日期：2010-02-17 00:00:00

abstract：BACKGROUND:Lumbo-sacral radiculopathy (LSR) is a common musculoskeletal disorder for which patients seek medical care and referrals for advanced imaging. However, accurate diagnosis remains challenging. Neuropathic pain screening questionnaires, clinical neurological examination and magnetic resonance imaging (MRI) are...

journal_title：BMC neurology

authors： Tawa N,Diener I,Louw Q,Rhoda A

更新日期：2019-05-30 00:00:00

abstract：BACKGROUND:To investigate the prognostic value of hyponatremia, defined as serum sodium level < 135 mEq/L, in radiation-induced brain necrosis (RN) patients. METHODS:We performed a retrospective analysis of the RN patients (The patients included in our study had a history of primary cancers including nasopharyngeal ca...

journal_title：BMC neurology

authors： Liao H,Zhu Z,Rong X,Wang H,Peng Y

更新日期：2018-08-29 00:00:00

abstract：BACKGROUND:Susac syndrome (SuS) is a rare condition characterized by a clinical triad of sensorineural hearing loss, branch artery occlusion and encephalopathy. This study reports an increased incidence of SuS in Israel. We describe the clinical characteristics of these patients, diagnostic procedures and the use and s...

journal_title：BMC neurology

authors： Wilf-Yarkoni A,Elkayam O,Aizenstein O,Oron Y,Furer V,Zur D,Goldstein M,Barequet D,Hallevi H,Karni A,Habot-Wilner Z,Regev K

更新日期：2020-09-02 00:00:00

abstract：BACKGROUND:The available health resources limit the amount of therapy that may be offered to children with cerebral palsy and the amount of training in each session may be insufficient to drive the neuroplastic changes, which are necessary for functional improvements to take place. The aim of this pilot study was to pr...

journal_title：BMC neurology

authors： Bilde PE,Kliim-Due M,Rasmussen B,Petersen LZ,Petersen TH,Nielsen JB

更新日期：2011-03-09 00:00:00