Abstract:
BACKGROUND:Migraine and Attention Deficit and Hyperactivity Disorder (ADHD) have been found to be associated in child and adolescent cohorts; however, the association has not been assessed in adults or otherwise healthy population. Assessing the comorbidity between ADHD and migraine may clarify the etiopathology of both diseases. Thus, the objective is to assess whether migraine (with and without visual disturbances) and ADHD are comorbid disorders. METHODS:Participants from the Danish Blood Donor Study (N = 26,456, age 18-65, 46% female) were assessed for migraine and ADHD using the ASRS ver 1.1 clinically validated questionnaire and self-reported migraine in a cross-sectional study. Logistic regression was used to examine the comorbidity between migraine and ADHD, and their associated endophenotypes. RESULTS:Migraine was strongly associated with ADHD (OR = 1.8, 95% CI = 1.5-2.1), (238/6152 vs 690/19,376). There was a significant interaction between age and gender, with comorbidity increasing with age and female sex. Post-hoc analysis showed that migraine with visual disturbance was generally associated with a marginally higher risk of ADHD and this was independent of ADHD endophenotypes. CONCLUSION:Migraine and ADHD were demonstrated to be comorbid disorders; the association with ADHD was most prominent for participants with migraine with visual disturbances. Future studies will elucidate which genetic and environmental factors contribute to migraine-ADHD comorbidity.
journal_name
BMC Neuroljournal_title
BMC neurologyauthors
Hansen TF,Hoeffding LK,Kogelman L,Haspang TM,Ullum H,Sørensen E,Erikstrup C,Pedersen OB,Nielsen KR,Hjalgrim H,Paarup HM,Werge T,Burgdorf Kdoi
10.1186/s12883-018-1149-6subject
Has Abstractpub_date
2018-10-16 00:00:00pages
147issue
1issn
1471-2377pii
10.1186/s12883-018-1149-6journal_volume
18pub_type
杂志文章相关文献
BMC Neurology文献大全abstract:BACKGROUND:The study aims to assess the therapeutic benefits of motor imagery training in stroke patients with persistent motor weakness. There is evidence to suggest that mental rehearsal of movement can produce effects normally attributed to practising the actual movements. Imagining hand movements could stimulate th...
journal_title:BMC neurology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/1471-2377-6-39
更新日期:2006-10-26 00:00:00
abstract:BACKGROUND:Non-ataxic symptoms of spinocerebellar ataxias (SCAs) vary widely and often overlap with various types of SCAs. Duration and severity of the disease and genetic background may play a role in such phenotypic diversity. We conducted the study in order to study clinical characteristics of common SCAs in Thailan...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-14-75
更新日期:2014-04-05 00:00:00
abstract:BACKGROUND:Infectious basilar artery (BA) aneurysm has been occasionally reported to be generated from meningitis following transcranial operation. However, infectious BA aneurysm formed by intracranial infection after endoscopic endonasal operation has never been reported. CASE PRESENTATION:A 53-year-old man who was ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-01673-9
更新日期:2020-03-14 00:00:00
abstract:BACKGROUND:Periodic alternating ping-pong gaze (PPG) is a rare disease with few reports. To our knowledge, there was no report on anti GQ1b antibody syndrome accompanied by PPG. This paper reported a case of anti GQ1b antibody syndrome with Bickerstaff's Encephalitis (BBE) overlapping classic Guillain-Barre Syndrome (G...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-019-1258-x
更新日期:2019-02-19 00:00:00
abstract:BACKGROUND:BICAMS (Brief International Cognitive Assessment for Multiple Sclerosis) has been recently developed as brief, practical and universal assessment tool for cognitive impairment in MS subjects. It includes the Symbol Digit Modalities Test (SDMT), the California Verbal Learning Test-2 (CVLT2) and the Brief Visu...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-014-0171-6
更新日期:2014-09-10 00:00:00
abstract:BACKGROUND:Seizures are one of the most important neurologic complications of human immuno-deficiency virus (HIV)-negative cryptococcal meningitis. A better understanding of the risk associated factors can help predict those who will require treatment. METHODS:This 22-year retrospective study enrolled 180 patients. Pr...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-014-0208-x
更新日期:2014-10-13 00:00:00
abstract:BACKGROUND:"Anarchic hand" is a rare condition characterised by non-volitional, goal-directed movements of one arm. We report a case with analysis of structural and functional connectivity. CASE PRESENTATION:A 15 year old girl developed intermittent symptoms of intermanual conflict or anarchic hand as a result of trau...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0477-z
更新日期:2015-11-14 00:00:00
abstract:BACKGROUND:Elevated intracranial pressure from cerebral edema is the major cause of early mortality in acute stroke. Current treatment strategies to limit cerebral edema are not particularly effective. Some novel anti-edema measures have shown promising early findings in experimental stroke models. Vasopressin antagoni...
journal_title:BMC neurology
pub_type: 杂志文章,评审
doi:10.1186/s12883-014-0213-0
更新日期:2014-11-18 00:00:00
abstract:BACKGROUND:Complaints of unrefreshing sleep are a prominent component of chronic fatigue syndrome (CFS); yet, polysomnographic studies have not consistently documented sleep abnormalities in CFS patients. We conducted this study to determine whether alterations in objective sleep characteristics are associated with sub...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-7-40
更新日期:2007-12-05 00:00:00
abstract:BACKGROUND:Different apoptosis pathways activate caspase-3. In a study involving 27 patients with traumatic brain injury (TBI), higher caspase-3 levels were found in contusion brain tissue resected from non-survivors than from survivors. The objective of this study was to determine whether there is an association in TB...
journal_title:BMC neurology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12883-015-0485-z
更新日期:2015-11-06 00:00:00
abstract:BACKGROUND:The character of upper limb disorder in computer operators is subject to debate. A peripheral nerve-involvement is suggested from the common presence of a triad of symptoms consisting of pain, paraestesiae and subjective weakness, and from physical findings suggesting neuropathy. This study aimed to examine ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-6-40
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Complex Regional Pain Syndrome (CRPS) presents as chronic, continuous pain and sensory, autonomic, and motor abnormalities affecting one or more extremities. People with CRPS can also show changes in their perception of and attention to the affected body part and sensory information in the affected side of s...
journal_title:BMC neurology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12883-020-1604-z
更新日期:2020-02-19 00:00:00
abstract:BACKGROUND:Cognitive impairment commonly occurs in the acute phase post-stroke, but may persist with over half of all stroke survivors experiencing some form of long-term cognitive deficit. Recent evidence suggests that optimising secondary prevention adherence is a critical factor in preventing recurrent stroke and th...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0288-2
更新日期:2015-03-12 00:00:00
abstract:BACKGROUND:Neurogenic orthostatic hypotension (nOH) results from impaired vasoconstriction due to dysfunction of the autonomic nervous system and is commonly associated with Parkinson disease (PD), multiple system atrophy (MSA), and pure autonomic failure. nOH can increase the risk of falls due to symptoms that include...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-018-1129-x
更新日期:2018-08-25 00:00:00
abstract:BACKGROUND:Epigenetics underlying refractory epilepsy is poorly understood. DNA methylation may affect gene expression in epilepsy patients without affecting DNA sequences. Herein, we investigated the association between Carbamazepine-resistant (CBZ-resistant) epilepsy and EPHX1 methylation in a northern Han Chinese po...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-019-1308-4
更新日期:2019-06-04 00:00:00
abstract:BACKGROUND:Autonomic nervous system (ANS) dysfunction is present in up to one third of patients with tetanus. The prognostic value of ANS dysfunction is known in severe tetanus but its value is not well established in mild to moderate tetanus. METHODS:Medical records of all patients admitted with tetanus at two academ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-5-2
更新日期:2005-01-31 00:00:00
abstract:BACKGROUND:Embolectomy is the standard of care in acute ischemic stroke (AIS) caused by large vessel occlusion (LVO). Aim of this study was to compare two techniques: A Direct Aspiration First Pass Technique (ADAPT) and Stent-retriever Assisted Vacuum-locked Extraction (SAVE) stratified by the occluded vessel. METHODS...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-019-1291-9
更新日期:2019-04-15 00:00:00
abstract:BACKGROUND:We imaged the corticospinal tract (CST) and corticoreticular pathway (CRP) using diffusion tensor tractography (DTT) to evaluate the cause of muscle weakness in a patient who was exposed to high-voltage electricity. CASE PRESENTATION:A 39-year-old man presented with quadriparesis after high-voltage electric...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-01707-2
更新日期:2020-04-13 00:00:00
abstract:BACKGROUND:Parkinson's disease, the second most common neurodegenerative disease, is diagnostically defined by motor impairments, but also includes often under-recognized impairments in cognition, mood, sleep, and the autonomic nervous system. These problems can severely affect individuals' quality of life. In our prio...
journal_title:BMC neurology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12883-015-0506-y
更新日期:2015-12-15 00:00:00
abstract:BACKGROUND:Data from different studies suggest a favourable association between pretreatment with statins or hypercholesterolemia and outcome after ischaemic stroke. We examined whether there were differences in in-hospital mortality according to the presence or absence of statin therapy in a large population of first-...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-10-47
更新日期:2010-06-18 00:00:00
abstract:BACKGROUND:Chronic fatigue syndrome (CFS) is a disabling condition that affects approximately 800,000 adult Americans. The pathophysiology remains unknown and there are no diagnostic markers or characteristic physical signs or laboratory abnormalities. Most CFS patients complain of unrefreshing sleep and many of the po...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-4-6
更新日期:2004-04-19 00:00:00
abstract:BACKGROUND:Besides the defining involvement of upper and lower motor neurons, the involvement of extramotor structures has been increasingly acknowledged in amyotrophic lateral sclerosis (ALS). METHODS:Here we investigated a group of 14 mildly to moderately affected ALS patients and 14 age-matched healthy control part...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-13-148
更新日期:2013-10-18 00:00:00
abstract:BACKGROUND:Inflammatory reactions occurring in the brain after ischemia may contribute to secondary damage. In the present study, effects of minocycline, an anti-inflammatory agent, alone or in combination with mild hypothermia on focal embolic cerebral ischemia have been examined. METHODS:Focal ischemic injury was in...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-2-2
更新日期:2002-04-18 00:00:00
abstract:BACKGROUND:The Observational Skills Assessment Score (OSAS) measures amount and quality of use of the affected hand in children with unilateral Cerebral Palsy (CP) in bimanual activities and could therefore be a valuable addition to existing assessment tools. The OSAS consists of tasks that are age appropriate and requ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-13-152
更新日期:2013-10-21 00:00:00
abstract::Following publication of the original article [1], the authors reported an error in Table 2 wherein the item numbering in the first column is wrong. ...
journal_title:BMC neurology
pub_type: 已发布勘误
doi:10.1186/s12883-019-1454-8
更新日期:2019-09-13 00:00:00
abstract:BACKGROUND:Mixed pathology, particularly Alzheimer's disease with cerebrovascular lesions, is reported as the second most common cause of dementia. Research on mixed dementia typically includes people with a primary AD diagnosis and hence, little is known about the effects of co-existing amyloid pathology in people wit...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0459-1
更新日期:2015-10-12 00:00:00
abstract:BACKGROUND:Stroke represents one of the most costly and long-term disabling conditions in adulthood worldwide and there is a need to determine the effectiveness of rehabilitation programs in the late phase after stroke. Limited scientific support exists for training incorporating rhythm and music as well as therapeutic...
journal_title:BMC neurology
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2377-12-141
更新日期:2012-11-21 00:00:00
abstract:BACKGROUND:Post-translational modifications (PTMs) generate a tremendous protein diversity from the ~ 20,000 protein-coding genes of the human genome. In chronic pain conditions, exposure to pathological processes in the central nervous system could lead to disease-specific PTMs detectable in the cerebrospinal fluid (C...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-018-1116-2
更新日期:2018-08-16 00:00:00
abstract:BACKGROUND:In Asia, stroke incidence varies dramatically from country to country. Little is known about stroke incidence in Asians/Pacific Islanders in the US, where regional heterogeneity in Asian/Pacific Islander sub-populations is great. We sought to characterize both the national and regional incidences of first an...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-5-21
更新日期:2005-11-10 00:00:00
abstract:BACKGROUND:There is need for a cognitive test battery that can be easily used in clinical practice to detect or monitor cognitive performance in patients with multiple sclerosis (MS). In order to conduct, in this patient group, a preliminary investigation of the validity and utility of a brief computerized battery, the...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-11-68
更新日期:2011-06-07 00:00:00