Exploring the effects of coexisting amyloid in subcortical vascular cognitive impairment.

abstract：BACKGROUND:Deep brain stimulation of the subthalamic nucleus significantly improves motor function in patients with severe Parkinson's disease. However, the effects on nonmotor aspects remain uncertain. The present study investigated the effects of subthalamic nucleus deep brain stimulation on mood and psychosocial fun...

journal_title：BMC neurology

authors： Kaiser I,Kryspin-Exner I,Brücke T,Volc D,Alesch F

更新日期：2008-11-11 00:00:00

abstract：BACKGROUND:Post-translational modifications (PTMs) generate a tremendous protein diversity from the ~ 20,000 protein-coding genes of the human genome. In chronic pain conditions, exposure to pathological processes in the central nervous system could lead to disease-specific PTMs detectable in the cerebrospinal fluid (C...

journal_title：BMC neurology

authors： Bäckryd E,Edström S,Gerdle B,Ghafouri B

更新日期：2018-08-16 00:00:00

abstract：BACKGROUND:The recent SLEEMSA study that evaluated excessive daytime sleepiness (EDS) in Caucasian patients with multiple system atrophy (MSA) demonstrated that EDS was more frequent in patients (28%) than in healthy subjects (2%). However, the prevalence and determinants of EDS in other ethnic populations have not bee...

journal_title：BMC neurology

authors： Shimohata T,Nakayama H,Tomita M,Ozawa T,Nishizawa M

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Past studies found that cerebral developmental venous anomaly (DVA) is often concurrent with cavernous malformation (CM). But the reason of the concurrency remains unknown. The purpose of this study was to confirm whether angioarchitectural factors relate to the concurrence and which angioarchitectural facto...

journal_title：BMC neurology

authors： Yu T,Liu X,Lin X,Bai C,Zhao J,Zhang J,Zhang L,Wu Z,Wang S,Zhao Y,Meng G

更新日期：2016-09-22 00:00:00

abstract：BACKGROUND:The aim of this study was to examine the hospital readmissions in a 10 year follow-up of a stroke cohort previously studied for acute and subacute complications and to focus on their frequency, their causes and their timing. METHODS:The hospital records of 243 patients, 50% of a cohort of 489 patients acute...

journal_title：BMC neurology

authors： Rohweder G,Salvesen Ø,Ellekjær H,Indredavik B

更新日期：2017-06-19 00:00:00

abstract：BACKGROUND:Different apoptosis pathways activate caspase-3. In a study involving 27 patients with traumatic brain injury (TBI), higher caspase-3 levels were found in contusion brain tissue resected from non-survivors than from survivors. The objective of this study was to determine whether there is an association in TB...

journal_title：BMC neurology

authors： Lorente L,Martín MM,Argueso M,Ramos L,Solé-Violán J,Riaño-Ruiz M,Jiménez A,Borreguero-León JM

更新日期：2015-11-06 00:00:00

abstract：BACKGROUND:Data from different studies suggest a favourable association between pretreatment with statins or hypercholesterolemia and outcome after ischaemic stroke. We examined whether there were differences in in-hospital mortality according to the presence or absence of statin therapy in a large population of first-...

journal_title：BMC neurology

authors： Arboix A,García-Eroles L,Oliveres M,Targa C,Balcells M,Massons J

更新日期：2010-06-18 00:00:00

abstract：BACKGROUND:After discharge from hospital following a stroke, prescriptions of community-based rehabilitation are often downgraded to "maintenance" rehabilitation or discontinued. This classic therapeutic behavior stems from persistent confusion between lesion-induced plasticity, which lasts for the first 6 months essen...

journal_title：BMC neurology

authors： Gracies JM,Pradines M,Ghédira M,Loche CM,Mardale V,Hennegrave C,Gault-Colas C,Audureau E,Hutin E,Baude M,Bayle N,Neurorestore Study Group.

更新日期：2019-03-12 00:00:00

abstract：BACKGROUND:The medical imaging to differentiate World Health Organization (WHO) grade II (ODG2) from III (ODG3) oligodendrogliomas still remains a challenge. We investigated whether combination of machine leaning with radiomics from conventional T1 contrast-enhanced (T1 CE) and fluid attenuated inversion recovery (FLAI...

journal_title：BMC neurology

authors： Zhao SS,Feng XL,Hu YC,Han Y,Tian Q,Sun YZ,Zhang J,Ge XW,Cheng SC,Li XL,Mao L,Shen SN,Yan LF,Cui GB,Wang W

更新日期：2020-02-07 00:00:00

abstract：BACKGROUND:Hemifacial atrophy (Parry-Romberg syndrome) is a relatively rare disease. The etiology of the disease is not clear. Some authors postulate its relation with limited scleroderma linearis. Linear scleroderma "en coup de sabre" is characterized by clinical presence of most commonly one-sided linear syndrome. In...

journal_title：BMC neurology

authors： Bergler-Czop B,Lis-Swiety A,Brzezińska-Wcisło L

更新日期：2009-07-27 00:00:00

abstract：BACKGROUND:Robotic devices are expected to be widely used in various applications including support for the independent mobility of the elderly with muscle weakness and people with impaired motor function as well as support for nursing care that involves heavy laborious work. We evaluated the effects of a hybrid assist...

journal_title：BMC neurology

authors： Maeshima S,Osawa A,Nishio D,Hirano Y,Takeda K,Kigawa H,Sankai Y

更新日期：2011-09-27 00:00:00

abstract：BACKGROUND:Nosocomial infection (NI) control is an important issue in neurocritical care due to secondary brain damage and the increased morbidity and mortality of primary acute neurocritical care patients. The primary aim of this study was to determine incidence of nosocomial infections and multidrug-resistant bacteri...

journal_title：BMC neurology

authors： Spatenkova V,Bradac O,Fackova D,Bohunova Z,Suchomel P

更新日期：2018-03-07 00:00:00

abstract：BACKGROUND:"Anarchic hand" is a rare condition characterised by non-volitional, goal-directed movements of one arm. We report a case with analysis of structural and functional connectivity. CASE PRESENTATION:A 15 year old girl developed intermittent symptoms of intermanual conflict or anarchic hand as a result of trau...

journal_title：BMC neurology

authors： Basu AP,Taylor PN,Lowther E,Forsyth EO,Blamire AM,Forsyth RJ

更新日期：2015-11-14 00:00:00

abstract：BACKGROUND:The coexistence of distinct neurodegenerative diseases in single cases has recently attracted greater attention. The phenotypic co-occurrence of progressive supranuclear palsy (PSP) and amyotrophic lateral sclerosis (ALS) has been documented in several cases. That said, the clinicopathological comorbidity of...

journal_title：BMC neurology

authors： Fujita K,Matsubara T,Miyamoto R,Sumikura H,Takeuchi T,Maruyama Saladini K,Kawarai T,Nodera H,Udaka F,Kume K,Morino H,Kawakami H,Hasegawa M,Kaji R,Murayama S,Izumi Y

更新日期：2019-07-18 00:00:00

abstract：BACKGROUND:Sturge-Weber syndrome (SWS) is a rare and sporadic congenital neurocutaneous disorder, that is characterized by facial venous capillary malformation (port-wine birthmark), leptomeningeal venous malformation (angiomatosis), glaucoma, and neurologic problems. SWS can comorbid with other disorders in some patie...

journal_title：BMC neurology

authors： Deng L,Wang D,Ruan N,Fu P

更新日期：2019-05-03 00:00:00

abstract：BACKGROUND:Recent studies suggest that epigenetic factors may play an important role in the pathogenesis of Parkinson's disease (PD). In our previous work, we sequenced the exomes of sixteen patients from eight Chinese PD families using whole exome sequencing technology, consequently three patients from different pedig...

journal_title：BMC neurology

authors： Liao XX,Zhan ZX,Luo YY,Li K,Wang JL,Guo JF,Yan XX,Xia K,Tang BS,Shen L

更新日期：2013-12-11 00:00:00

abstract：BACKGROUND:Post-stroke depression (PSD) is a mood disorder characterized by depression and anhedonia caused by stroke. Metabolomics identified metabolites associated with PSD, but previous studies are based on gas chromatography (GC)/mass spectrometry (MS). This study aimed to perform a liquid chromatography (LC)-MS-ba...

journal_title：BMC neurology

authors： Wang M,Gui X,Wu L,Tian S,Wang H,Xie L,Wu W

更新日期：2020-06-20 00:00:00

abstract：BACKGROUND:Spastic paraplegia, optic atrophy and neuropathy (Spoan syndrome) is an autosomal recessive disease with approximately 70 cases recorded in Brazil and Egypt. METHODS:This is a prospective longitudinal study performed with 47 patients affected with Spoan syndrome of seven communities of Rio Grande do Norte (...

journal_title：BMC neurology

authors： Galvão CRC,Cavalcante PMA,Olinda R,Graciani Z,Zatz M,Kok F,Santos S,Lancman S

更新日期：2019-10-27 00:00:00

abstract：BACKGROUND:To describe the clinical phenotype of paroxysmal extreme pain disorder, an autosomal dominant condition in four members in one family with the mutation NM_002977.3:c.3892G > T (p.Val1298Phe) in the SCN9A gene. Clinical examinations and details from members of one Polish family were collected, including age a...

journal_title：BMC neurology

authors： Stępień A,Sałacińska D,Staszewski J,Durka-Kęsy M,Dobrogowski J

更新日期：2020-05-13 00:00:00

abstract：BACKGROUND:Complaints of unrefreshing sleep are a prominent component of chronic fatigue syndrome (CFS); yet, polysomnographic studies have not consistently documented sleep abnormalities in CFS patients. We conducted this study to determine whether alterations in objective sleep characteristics are associated with sub...

journal_title：BMC neurology

authors： Majer M,Jones JF,Unger ER,Youngblood LS,Decker MJ,Gurbaxani B,Heim C,Reeves WC

更新日期：2007-12-05 00:00:00

abstract：BACKGROUND:Sciatica is a condition that is characterised by radicular pain in the leg and primarily caused by a herniated lumbar intervertebral disk. In addition to leg pain, patients can experience back pain, leg numbness and leg weakness resulting in decreased productivity and social activity. The majority of sciatic...

journal_title：BMC neurology

authors： Verheijen E,Munts AG,van Haagen O,de Vries D,Dekkers O,van den Hout W,Vleggeert-Lankamp C

更新日期：2019-09-03 00:00:00

abstract：BACKGROUND:Spinal cord infarction (SCI) is rarely caused by vertebral artery dissection (VAD), which is an important cause of posterior circulation stroke in young and middle-aged patients. We report the case of a middle-aged patient without obvious risk factors for atherosclerosis who had SCI from right VAD. CASE PRE...

journal_title：BMC neurology

authors： Meng YY,Dou L,Wang CM,Kong DZ,Wei Y,Wu LS,Yang Y,Zhou HW

更新日期：2019-12-12 00:00:00

abstract：BACKGROUND:Primary familial brain calcification is a rare autosomal dominant or recessive neurodegenerative disease, characterized by bilateral brain calcifications in different areas of the brain. It is a clinically heterogeneous disease and patients are reported to exhibit a wide spectrum of neurological and psychiat...

journal_title：BMC neurology

authors： Mathorne SW,Sørensen K,Fagerberg C,Bode M,Hertz JM

更新日期：2019-04-12 00:00:00

abstract：BACKGROUND:Cerebral venous sinus thrombosis (CVST) is a relatively rare cerebrovascular condition which accounts for 0.5% of all strokes. Risk of CVST has been documented in patients with numerous conditions including central nervous system infections, however, Japanese encephalitis (JE, epidemic encephalitis type B) w...

journal_title：BMC neurology

authors： Jia M,Xiong N,Huang J,Wang Y,Zhang X,Zhang Z,Cao X,Lin Z,Wang T

更新日期：2012-06-19 00:00:00

abstract：BACKGROUND:THK5351 and flortaucipir tau ligands have high affinity for paired helical filament tau, yet diverse off-target bindings have been reported. Recent data support the hypothesis that THK5351 binds to monoamine oxidase B (MAO-B) expressed from reactive astrocytes and that flortaucipir has an affinity toward MAO...

journal_title：BMC neurology

authors： Kim HJ,Cho H,Park S,Jang H,Ryu YH,Choi JY,Moon SH,Oh SJ,Oh M,Na DL,Lyoo CH,Kim EJ,Seeley WW,Kim JS,Choi KC,Seo SW

更新日期：2019-08-29 00:00:00

abstract：BACKGROUND:The Observational Skills Assessment Score (OSAS) measures amount and quality of use of the affected hand in children with unilateral Cerebral Palsy (CP) in bimanual activities and could therefore be a valuable addition to existing assessment tools. The OSAS consists of tasks that are age appropriate and requ...

journal_title：BMC neurology

authors： Speth L,Janssen-Potten Y,Leffers P,Rameckers E,Defesche A,Geers R,Smeets R,Vles H

更新日期：2013-10-21 00:00:00

abstract：BACKGROUND:In adults, the anastomosis between carotid and vertebrobasilar arteries is usually the posterior communicating artery, sometimes the primitive trigeminal artery. In this case, the basilar artery fed the internal carotid artery through the pontine-to-tentorial artery anastomosis after severe stenosis from tra...

journal_title：BMC neurology

authors： Liu X,Li B,Liu Y,Wu H,Zhang H,Dou L,Liu C

更新日期：2020-03-17 00:00:00

abstract：BACKGROUND:Road traffic accidents are known to be the main cause of traumatic brain injury (TBI). TBI is also a leading cause of death and disability. This study, by means of the idiographic approach (single-case experimental designs using multiple-baseline designs), has examined whether methylphenidate (MPH - trade na...

journal_title：BMC neurology

authors： Al-Adawi S,Al-Naamani A,Jaju S,Al-Farsi YM,Dorvlo ASS,Al-Maashani A,Al-Adawi SSH,Moustafa AA,Al-Sibani N,Essa MM,Burke DT,Qoronfleh MW

更新日期：2020-03-19 00:00:00

abstract：BACKGROUND:Partially thrombosed giant aneurysms at the basilar apex (BA) artery are challenging lesions with a poor prognosis if left untreated. Here we describe a rare case of extensive brain edema after growth of a surgically treated and thrombosed giant basilar apex aneurysm. CASE PRESENTATION:We performed a proxim...

journal_title：BMC neurology

authors： García-Pérez D,Panero I,Eiriz C,Moreno LM,Munarriz PM,Paredes I,Lagares A,Alén JF

更新日期：2020-06-06 00:00:00

abstract：BACKGROUND:There is much discourse in healthcare about the importance of client-centred rehabilitation, however in the realm of community-based therapy post-stroke there has been little investigation into the efficacy of goal-directed practice that reflects patients' valued activities. In addition, the effect of active...

journal_title：BMC neurology

authors： Graven C,Brock K,Hill K,Ames D,Cotton S,Joubert L

更新日期：2011-06-18 00:00:00