Motor impairment in a rare form of spastic paraplegia (Spoan syndrome): a 10-year follow-up.

abstract：BACKGROUND:Mixed pathology, particularly Alzheimer's disease with cerebrovascular lesions, is reported as the second most common cause of dementia. Research on mixed dementia typically includes people with a primary AD diagnosis and hence, little is known about the effects of co-existing amyloid pathology in people wit...

journal_title：BMC neurology

authors： Dao E,Hsiung GY,Sossi V,Jacova C,Tam R,Dinelle K,Best JR,Liu-Ambrose T

更新日期：2015-10-12 00:00:00

abstract：BACKGROUNDS:Glioma is the most fatal primary brain glioma in central nervous system mainly attributed to its high invasion. Prucalopride, a Serotonin-4 (5-HT4) receptor agonist, has been reported to regulate neurodevelopment. This study aimed to investigate the influence of the Prucalopride on glioma cells and unveil u...

journal_title：BMC neurology

authors： Qiao H,Wang YB,Gao YM,Bi LL

更新日期：2018-06-04 00:00:00

abstract：BACKGROUND:The partial form of the complex regional pain syndrome of the hand type 1 (CRPS 1), involving only 1 to 3 fingers, is a rare condition first described in 1972. The aim of the study is to define more precisely the diagnosis workup and the prognosis of this clinical entity. METHODS:Retrospective study of CRPS...

journal_title：BMC neurology

authors： Konzelmann M,Deriaz O,Luthi F

更新日期：2013-03-18 00:00:00

abstract：BACKGROUND:Almost 40% of stroke patients have a poor outcome at 3 months after the index event. Predictors for stroke outcome in the early acute phase may help to tailor stroke treatment. Infection and inflammation are considered to influence stroke outcome. METHODS:In a prospective multicenter study in Germany and Sp...

journal_title：BMC neurology

authors： Mengel A,Ulm L,Hotter B,Harms H,Piper SK,Grittner U,Montaner J,Meisel C,Meisel A,Hoffmann S

更新日期：2019-07-03 00:00:00

abstract：BACKGROUND:Silent brain infarcts are detected by neuroimaging in up to 20% of asymptomatic patients based on population studies. They are five times more frequent than stroke in general population, and increase significantly both with advancing age and hypertension. Moreover, they are independently associated with the ...

journal_title：BMC neurology

authors： Riba-Llena I,Jarca CI,Mundet X,Tovar JL,Orfila F,López-Rueda A,Nafría C,Fernández JL,Castañé X,Domingo M,Alvarez-Sabín J,Fernández-Cortiñas I,Maisterra O,Montaner J,Delgado P

更新日期：2013-10-02 00:00:00

abstract：BACKGROUND:Association of leukoencephalopathy and atypical mycobacteriosis has been rarely reported. We present a case that is relevant for its unusual presentation and because it may shed further light on the pathogenic mechanisms underlying reversible encephalopathies. CASE REPORT:We report the case of a Hispanic 64...

journal_title：BMC neurology

authors： Oliveira MC,Sato DK,Soares-Neto HR,Lucato LT,Callegaro D,Nitrini R,Medeiros RS,Misu T,Fujihara K,Castro LH

更新日期：2015-09-02 00:00:00

abstract：BACKGROUND:Many migraineurs who seek care in headache clinics are refractory to treatment, despite advances in headache therapies. Epidemiology is poorly characterized, because diagnostic criteria for refractory migraine were not available until recently. We aimed to determine the frequency of refractory migraine in pa...

journal_title：BMC neurology

authors： Irimia P,Palma JA,Fernandez-Torron R,Martinez-Vila E

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Ramsay Hunt syndrome (RHS) is caused by a reactivation of varicella-zoster virus (VZV) infection, and it is characterized by the symptoms of facial paralysis, otalgia, auricular rash, and/or an oral lesion. Elderly patients or immunocompromised patients, deep pain at the initial visit and no prompt treatment...

journal_title：BMC neurology

authors： Liao YM,Lu HF,Xie P,Zhao Y,Han Q,Zhang QX,Zuo XH,Si YN,Bao HG

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND:Assessing primary rehabilitation needs in patients with acquired brain injury is a challenge due to case complexity and the heterogeneity of symptoms after brain injury. The Rehabilitation Complexity Scale-Extended (RCS-E) is an instrument used in assessment of rehabilitation complexity in patients with seve...

journal_title：BMC neurology

authors： Maribo T,Pedersen AR,Jensen J,Nielsen JF

更新日期：2016-10-21 00:00:00

abstract：BACKGROUND:To assess the feasibility of using automated capture of Electronic Medical Record (EMR) data to build predictive models for amyotrophic lateral sclerosis (ALS) outcomes. METHODS:We used an Informatics for Integrating Biology and the Bedside search discovery tool to identify and extract data from 354 ALS pat...

journal_title：BMC neurology

authors： Karanevich AG,Weisbrod LJ,Jawdat O,Barohn RJ,Gajewski BJ,He J,Statland JM

更新日期：2018-12-14 00:00:00

abstract：BACKGROUND:We aimed to develop a tool, the hemorrhagic transformation (HT) index (HTI), to predict any HT within 14 days after middle cerebral artery (MCA) stroke onset regardless of the intravenous recombinant tissue plasminogen activator (IV rtPA) use. That is especially important in the light of missing evidence-bas...

journal_title：BMC neurology

authors： Kalinin MN,Khasanova DR,Ibatullin MM

更新日期：2017-09-07 00:00:00

abstract：BACKGROUND:The COVID-19 pandemic, which broke out in Wuhan in 2019, has become the global health crisis of our time. Elderly patients with certain fundamental diseases are more likely to develop severe cases. The secondary lesion following viral infection have only rarely been reported. CASE PRESENTATION:We here repor...

journal_title：BMC neurology

authors： Fu B,Chen Y,Li P

更新日期：2021-01-05 00:00:00

abstract：BACKGROUND:Fatigue is a common complaint in multiple sclerosis (MS) and often interferes with daily functioning. Both clinicians and researchers may need to detect high levels of fatigue impact using a time and effort efficient tool. This study evaluates the psychometric properties of a rapid screening instrument for f...

journal_title：BMC neurology

authors： Kos D,Nagels G,D'Hooghe MB,Duportail M,Kerckhofs E

更新日期：2006-08-17 00:00:00

abstract：BACKGROUND:Human serum paraoxonase 1 (PON1) plays a major role in the metabolism of several organophosphorus compounds. The enzyme is encoded by the polymorphic gene PON1, located on chromosome 7q21.3. Aiming to identify genetic variations related to the risk of developing brain tumors, we investigated the putative ass...

journal_title：BMC neurology

authors： Martínez C,Molina JA,Alonso-Navarro H,Jiménez-Jiménez FJ,Agúndez JA,García-Martín E

更新日期：2010-08-19 00:00:00

abstract：BACKGROUND:Dorsolateral medullary infarction (Wallenberg syndrome) is rare in clinical practice; however, the subsequent corneal lesions are more uncommon. To our knowledge, only one such case was previously reported. We report a similar case with successful treatment and recovery, and analyse both cases to address the...

journal_title：BMC neurology

authors： Wu S,Li N,Xia F,Sidlauskas K,Lin X,Qian Y,Gao W,Zhang Q

更新日期：2014-12-04 00:00:00

abstract：BACKGROUND:Migraine and Attention Deficit and Hyperactivity Disorder (ADHD) have been found to be associated in child and adolescent cohorts; however, the association has not been assessed in adults or otherwise healthy population. Assessing the comorbidity between ADHD and migraine may clarify the etiopathology of bot...

journal_title：BMC neurology

authors： Hansen TF,Hoeffding LK,Kogelman L,Haspang TM,Ullum H,Sørensen E,Erikstrup C,Pedersen OB,Nielsen KR,Hjalgrim H,Paarup HM,Werge T,Burgdorf K

更新日期：2018-10-16 00:00:00

abstract：BACKGROUND:High adherence to a Mediterranean Diet is associated with reduced incidence and mortality of acute ischemic stroke (AIS) but may also be associated with severity. Our purpose was to investigate the association of adherence to a Mediterranean diet and severity in a prospective hospital register of AIS patient...

journal_title：BMC neurology

authors： Lavados PM,Mazzon E,Rojo A,Brunser AM,Olavarría VV

更新日期：2020-06-23 00:00:00

abstract：BACKGROUND:Multiple sclerosis is a chronic, incurable, demyelinating disease that requires long-term treatment. Rates of non-adherence to prescribed therapy of up to 50% have been reported for chronic diseases. Strategies to improve treatment adherence are therefore of the utmost importance. This study will evaluate th...

journal_title：BMC neurology

authors： Zettl UK,Bauer-Steinhusen U,Glaser T,Hechenbichler K,Limmroth V,Study Group.

更新日期：2013-09-06 00:00:00

abstract：BACKGROUND:Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants for the treatment of depression in patients with Parkinson's Disease (PD) but data on their efficacy are controversial. METHODS:We conducted a systematic review and meta-analysis of randomized controlled trials ...

journal_title：BMC neurology

authors： Skapinakis P,Bakola E,Salanti G,Lewis G,Kyritsis AP,Mavreas V

更新日期：2010-06-21 00:00:00

abstract：BACKGROUND:Amyotrophic lateral sclerosis is a rapidly progressive neurodegenerative disorder characterised by loss of motor neurons leading to severe weakness and death from respiratory failure within 3-5 years. Riluzole prolongs survival in ALS. A published report has suggested a dramatic effect of lithium carbonate o...

journal_title：BMC neurology

authors： Al-Chalabi A,Shaw PJ,Young CA,Morrison KE,Murphy C,Thornhill M,Kelly J,Steen IN,Leigh PN,UKMND-LiCALS.

更新日期：2011-09-21 00:00:00

abstract：BACKGROUND:French Guiana has the highest incidence of ischemic and hemorrhagic stroke of all French territories. However, there is no further information on the epidemiology and management of stroke in French Guiana. Our goal was to describe the characteristics of patients in French Guiana in order to generate hypothes...

journal_title：BMC neurology

authors： Rochemont DR,Mimeau E,Misslin-Tritsch C,Papaix-Puech M,Delmas E,Bejot Y,DeToffol B,Fournel I,Nacher M

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:To describe the clinical phenotype of paroxysmal extreme pain disorder, an autosomal dominant condition in four members in one family with the mutation NM_002977.3:c.3892G > T (p.Val1298Phe) in the SCN9A gene. Clinical examinations and details from members of one Polish family were collected, including age a...

journal_title：BMC neurology

authors： Stępień A,Sałacińska D,Staszewski J,Durka-Kęsy M,Dobrogowski J

更新日期：2020-05-13 00:00:00

abstract：BACKGROUND:In adults, the anastomosis between carotid and vertebrobasilar arteries is usually the posterior communicating artery, sometimes the primitive trigeminal artery. In this case, the basilar artery fed the internal carotid artery through the pontine-to-tentorial artery anastomosis after severe stenosis from tra...

journal_title：BMC neurology

authors： Liu X,Li B,Liu Y,Wu H,Zhang H,Dou L,Liu C

更新日期：2020-03-17 00:00:00

abstract：BACKGROUND:Osteogenesis imperfecta (OI) is a heterogeneous group of inherited disorders that occur owing to the abnormalities in type 1 collagen, and is characterized by increased bone fragility and other extraskeletal manifestations. We report the case of a patient who was diagnosed with OI following subarachnoid hemo...

journal_title：BMC neurology

authors： Hirohata T,Miyawaki S,Mizutani A,Iwakami T,Yamada S,Nishido H,Suzuki Y,Miyamoto S,Hoya K,Murakami M,Matsuno A

更新日期：2014-07-23 00:00:00

abstract：BACKGROUND:Autosomal recessive cerebellar ataxias (ARCA) are a group of neurodegenerative disorders characterized by early onset of gait impairment, disturbed limb coordination, dysarthria, and eye movement abnormalities, most likely due to the degeneration of cerebellum, brainstem, and spinal cord. Despite of the rari...

journal_title：BMC neurology

authors： Lu C,Zheng YC,Dong Y,Li HF

更新日期：2016-09-20 00:00:00

abstract：BACKGROUND:Cerebral amyloid angiopathy (CAA) refers to the deposition of β-amyloid (Aβ) peptides in the wall of brain vasculature, commonly involving capillaries and arterioles. Also being considered a part of CAA is the Aβ deposition in leptomeninge. The cellular origin of angiopathic Aβ and the pathogenic course of C...

journal_title：BMC neurology

authors： Xue ZQ,He ZW,Yu JJ,Cai Y,Qiu WY,Pan A,Gai WP,Cai H,Luo XG,Ma C,Yan XX

更新日期：2015-05-02 00:00:00

abstract：:Following publication of the original article [1], the authors reported an error in Table 2 wherein the item numbering in the first column is wrong. ...

journal_title：BMC neurology

authors： da Silva ESM,Santos GL,Catai AM,Borstad A,Furtado NPD,Aniceto IAV,Russo TL

更新日期：2019-09-13 00:00:00

abstract：BACKGROUND:Stroke increases the risk of cognitive impairment even several years after the stroke event. The exact mechanisms of post-stroke cognitive decline are unclear, but the immunological response to stroke might play a role. The aims of the StrokeCog study are to examine the associations between immunological res...

journal_title：BMC neurology

authors： Drag LL,Mlynash M,Nassar H,Osborn E,Kim DE,Angst MS,Aghaeepour N,Buckwalter M,Lansberg MG

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:Machado-Joseph disease (MJD), or spinocerebellar ataxia type 3 (SCA3), is an autosomal dominant neurodegenerative disorder of late onset, which is caused by a CAG repeat expansion in the coding region of the ATXN3 gene. This disease presents clinical heterogeneity, which cannot be completely explained by the...

journal_title：BMC neurology

authors： Bettencourt C,Santos C,Coutinho P,Rizzu P,Vasconcelos J,Kay T,Cymbron T,Raposo M,Heutink P,Lima M

更新日期：2011-10-24 00:00:00

abstract：BACKGROUND:Complex Regional Pain Syndrome (CRPS) presents as chronic, continuous pain and sensory, autonomic, and motor abnormalities affecting one or more extremities. People with CRPS can also show changes in their perception of and attention to the affected body part and sensory information in the affected side of s...

journal_title：BMC neurology

authors： Halicka M,Vittersø AD,Proulx MJ,Bultitude JH

更新日期：2020-02-19 00:00:00