Neurotrophic keratopathy due to dorsolateral medullary infarction (Wallenberg syndrome): case report and literature review.

abstract：BACKGROUND:The autophagic vacuolar myopathies (AVM) are a group of inherited myopathies defined by the presence of autophagic vacuoles in pathological muscle specimens. AVM can be categorized into three groups: acid maltase deficiency, myopathies characterized by autophagic vacuoles with unique sarcolemmal features, an...

journal_title：BMC neurology

authors： Bokuda K,Sugaya K,Tamura S,Miyamoto K,Matsubara S,Komori T

更新日期：2012-11-21 00:00:00

abstract：BACKGROUND:Chronic fatigue syndrome (CFS) is a disabling condition that affects approximately 800,000 adult Americans. The pathophysiology remains unknown and there are no diagnostic markers or characteristic physical signs or laboratory abnormalities. Most CFS patients complain of unrefreshing sleep and many of the po...

journal_title：BMC neurology

authors： Unger ER,Nisenbaum R,Moldofsky H,Cesta A,Sammut C,Reyes M,Reeves WC

更新日期：2004-04-19 00:00:00

abstract：BACKGROUND:Recent consensus guidelines recommend pregabalin as a first-tier treatment for painful diabetic peripheral neuropathy (DPN). We evaluated the efficacy of pregabalin 600 mg/d (300 mg dosed BID) versus placebo for relieving DPN-associated neuropathic pain, and assessed its safety using objective measures of ne...

journal_title：BMC neurology

authors： Arezzo JC,Rosenstock J,Lamoreaux L,Pauer L

更新日期：2008-09-16 00:00:00

abstract：BACKGROUND:Cognitive disorders, such as memory disturbances, are often observed following a subarachnoid hemorrhage. We present a very rare case where rupture of a posterior cerebral artery aneurysm caused restricted damage to the hippocampus unilaterally, and caused memory disturbances. CASE PRESENTATION:A 56-year-ol...

journal_title：BMC neurology

authors： Maeshima S,Osawa A,Yamane F,Shimaguchi H,Ochiai I,Yoshihara T,Uemiya N,Kanazawa R,Ishihara S

更新日期：2014-03-07 00:00:00

abstract：BACKGROUND:Recovery patterns of upper extremity motor function have been described in several longitudinal studies, but most of these studies have had selected samples, short follow up times or insufficient outcomes on motor function. The general understanding is that improvements in upper extremity occur mainly during...

journal_title：BMC neurology

authors： Alt Murphy M,Persson HC,Danielsson A,Broeren J,Lundgren-Nilsson A,Sunnerhagen KS

更新日期：2011-05-25 00:00:00

abstract：BACKGROUND:Recent exercise guidelines for people with multiple sclerosis (MS) recommend a minimum of 30 min moderate intensity aerobic exercise and resistance exercise twice per week. This trial compared the secondary outcomes of a combined 10-week guideline based intervention and a Social Cognitive Theory (SCT) educat...

journal_title：BMC neurology

authors： Coote S,Uszynski M,Herring MP,Hayes S,Scarrott C,Newell J,Gallagher S,Larkin A,Motl RW

更新日期：2017-06-24 00:00:00

abstract：BACKGROUND:Neuromyelitis optica (NMO) includes transverse myelitis, optic neuritis and brain lesions. Recent studies have indicated that the brainstem is an important site of attack in NMO. Longitudinally extensive transverse myelitis (LETM) is an important component of the clinical diagnosis of NMO. The frequency of b...

journal_title：BMC neurology

authors： Asgari N,Skejoe HP,Lillevang ST,Steenstrup T,Stenager E,Kyvik KO

更新日期：2013-04-08 00:00:00

abstract：BACKGROUND:Fatigue is a common complaint in multiple sclerosis (MS) and often interferes with daily functioning. Both clinicians and researchers may need to detect high levels of fatigue impact using a time and effort efficient tool. This study evaluates the psychometric properties of a rapid screening instrument for f...

journal_title：BMC neurology

authors： Kos D,Nagels G,D'Hooghe MB,Duportail M,Kerckhofs E

更新日期：2006-08-17 00:00:00

abstract：BACKGROUND:Cholinesterase inhibitors can delay the progression of Alzheimer's disease (AD). Several clinical trials of the drug in moderate to severe AD have consistently reported clinically positive effects. A combining effect with psychosocial intervention was reported in mild to moderate AD patients. Since a therape...

journal_title：BMC neurology

authors： Meguro K,Ouchi Y,Akanuma K,Meguro M,Kasai M

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:Clinical trials are the hallmark of evidence-based medicine, but recruitment is often challenging, especially in stroke trials investigating patients not being able to give informed consent. In some nations, ethics committees will not approve of inclusion in a clinical study via consent of a legal representa...

journal_title：BMC neurology

authors： Hotter B,Ulm L,Hoffmann S,Katan M,Montaner J,Bustamante A,Meisel A

更新日期：2017-12-04 00:00:00

abstract：BACKGROUND:In Asia, stroke incidence varies dramatically from country to country. Little is known about stroke incidence in Asians/Pacific Islanders in the US, where regional heterogeneity in Asian/Pacific Islander sub-populations is great. We sought to characterize both the national and regional incidences of first an...

journal_title：BMC neurology

authors： Nguyen-Huynh MN,Johnston SC

更新日期：2005-11-10 00:00:00

abstract：BACKGROUND:Post-stroke depression (PSD) is a mood disorder characterized by depression and anhedonia caused by stroke. Metabolomics identified metabolites associated with PSD, but previous studies are based on gas chromatography (GC)/mass spectrometry (MS). This study aimed to perform a liquid chromatography (LC)-MS-ba...

journal_title：BMC neurology

authors： Wang M,Gui X,Wu L,Tian S,Wang H,Xie L,Wu W

更新日期：2020-06-20 00:00:00

abstract：BACKGROUND:Acceptance and Commitment Therapy (ACT), as a type of behavioral therapy, attempts to respond to changes in people's performance and their relationship to events. ACT can affect sleep quality by providing techniques to enhance the flexibility of patients' thoughts, yet maintaining mindfullness. Therefore, fo...

journal_title：BMC neurology

authors： Salari N,Khazaie H,Hosseinian-Far A,Khaledi-Paveh B,Ghasemi H,Mohammadi M,Shohaimi S

更新日期：2020-08-13 00:00:00

abstract：BACKGROUND:Prevalence of degenerative dementias and dementias associated with cerebrovascular disease is increasing. Dementia is one of the most significant public health problem. In recent years, the role of vascular risk factors (hypertension, diabetes mellitus and hypercholesterolemia) and depression has been evalua...

journal_title：BMC neurology

authors： Fernández Martínez M,Castro Flores J,Pérez de Las Heras S,Mandaluniz Lekumberri A,Gordejuela Menocal M,Zarranz Imirizaldu JJ

更新日期：2008-10-15 00:00:00

abstract：BACKGROUND:DNA methyltransferase 1 (EC 2.1.1.37), encoded by DNMT1 gene, is one of key enzymes in maintaining DNA methylation patterns of the human genome. It plays a crucial role in embryonic development, imprinting and genome stability, cell differentiation. The dysfunction of this group of enzymes can lead to a vari...

journal_title：BMC neurology

authors： Zheng W,Yan Z,He R,Huang Y,Lin A,Huang W,Su Y,Li S,Zhang VW,Xie H

更新日期：2018-10-20 00:00:00

abstract：BACKGROUND:Vascular cognitive impairment-no dementia (VCIND) refers to the early or mild cognitive impairment induced by cerebral vascular injury. Research shows that serum total homocysteine (tHcy) level is an independent risk factor for cerebral vascular disease and may be closely related to cognitive function.Curren...

journal_title：BMC neurology

authors： Jiang B,Chen Y,Yao G,Yao C,Zhao H,Jia X,Zhang Y,Ge J,Qiu E,Ding C

更新日期：2014-11-30 00:00:00

abstract：BACKGROUND:This multicenter, double-blind, placebo-controlled study assessed the efficacy of rotigotine transdermal patch on apathy and motor symptoms in patients with Parkinson's disease (PD). METHODS:Patients with PD-associated apathy (Unified Parkinson's Disease Rating Scale [UPDRS] I item 4 [motivation] ≥2 and pat...

journal_title：BMC neurology

authors： Hauser RA,Slawek J,Barone P,Dohin E,Surmann E,Asgharnejad M,Bauer L

更新日期：2016-06-07 00:00:00

abstract：BACKGROUND:Sub-cortical vascular ischaemia is the second most common etiology contributing to cognitive impairment in older adults, and is frequently under-diagnosed and under-treated. Although evidence is mounting that exercise has benefits for cognitive function among seniors, very few randomized controlled trials of...

journal_title：BMC neurology

authors： Liu-Ambrose T,Eng JJ,Boyd LA,Jacova C,Davis JC,Bryan S,Lee P,Brasher P,Hsiung GY

更新日期：2010-02-17 00:00:00

abstract：BACKGROUND:Women have been reported to show more frequent recanalization and better recovery after intravenous (IV) recombinant tissue plasminogen activator (rt-PA) treatment for acute stroke compared with men. To investigate this we studied a series of stroke patients receiving IV rt-PA and undergoing acute transcrani...

journal_title：BMC neurology

authors： Al-hussain F,Hussain MS,Molina C,Uchino K,Shuaib A,Demchuk AM,Alexandrov AV,Saqqur M,CLOTBUST Investigators.

更新日期：2014-03-26 00:00:00

abstract：BACKGROUND:The COVID-19 pandemic, which broke out in Wuhan in 2019, has become the global health crisis of our time. Elderly patients with certain fundamental diseases are more likely to develop severe cases. The secondary lesion following viral infection have only rarely been reported. CASE PRESENTATION:We here repor...

journal_title：BMC neurology

authors： Fu B,Chen Y,Li P

更新日期：2021-01-05 00:00:00

abstract：BACKGROUND:Adrenomyeloneuropathy (AMN) is one of several phenotypes of the adrenoleukodystrophy spectrum caused by mutations in the ABCD1 gene on the X chromosome. An inflammatory component is part of the disease complex ranging from severe childhood CNS demyelination to spinal cord and peripheral nerve degeneration. ...

journal_title：BMC neurology

authors： Jønch AE,Danielsen ER,Thomsen C,Meden P,Svenstrup K,Nielsen JE

更新日期：2012-09-26 00:00:00

abstract：BACKGROUND:Cubital tunnel syndrome is common nerve compression syndrome among peripheral nerve compression diseases. However, the syndrome caused by intraneural ganglion cysts has been rarely reported. Medical approaches, like ultrasound-guided aspiration and open surgical treatment remain to be discussed. CASE PRESEN...

journal_title：BMC neurology

authors： Li P,Lou D,Lu H

更新日期：2018-12-22 00:00:00

abstract：BACKGROUND:This study aimed to investigate the prevalence and clinical relevance of chronic cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis (MS) patients and healthy controls using extra- and intracranial colour Doppler sonography. METHODS:We examined 146 MS patients, presenting with a clinically isol...

journal_title：BMC neurology

authors： Lanzillo R,Mancini M,Liuzzi R,Di Donato O,Salvatore E,Maglio V,Vacca G,Amato L,D'Anna G,Brunetti A,Brescia Morra V

更新日期：2013-02-13 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) is common and highly heritable with many genes and gene variants associated with AD in one or more studies, including APOE ε2/ε3/ε4. However, the genetic backgrounds for normal cognition, mild cognitive impairment (MCI) and AD in terms of changes in cerebrospinal fluid (CSF) levels o...

journal_title：BMC neurology

authors： Han MR,Schellenberg GD,Wang LS,Alzheimer's Disease Neuroimaging Initiative.

更新日期：2010-10-08 00:00:00

abstract：BACKGROUND:It has been recently demonstrated that in Frontotemporal Lobar Degeneration (FTLD) memory deficits at presentation are commoner than previously thought. Apolipoprotein E (ApoE) genotype, the major genetic risk factor in sporadic late-onset Alzheimer Disease (AD), modulates cerebral perfusion in late middle-a...

journal_title：BMC neurology

authors： Borroni B,Perani D,Archetti S,Agosti C,Paghera B,Bellelli G,Di Luca M,Padovani A

更新日期：2006-08-24 00:00:00

abstract：BACKGROUND:The insular cortex is not routinely removed in modified functional hemispherectomy due to the risk of injury to the main arteries and to deep structures. Our study evaluates the safety and usefulness of applying intraoperative electrocorticography (ECoG) on the insular during the hemispherectomy. METHODS:We...

journal_title：BMC neurology

authors： Kim GH,Seo JH,Baumgartner JE,Ajmal F,Lee KH

更新日期：2017-08-25 00:00:00

abstract：BACKGROUND:Decision-making is an essential function of everyday life. Decision-making under explicit risk requires developing advantageous decision strategies based on fixed outcomes (e.g., probabilities of winning or losing a bet). Decision-making and its neural substrates have been rarely studied in MS. We expected p...

journal_title：BMC neurology

authors： Radomski AD,Power C,Purdon SE,Emery DJ,Blevins G,Warren KG,Fujiwara E

更新日期：2015-04-23 00:00:00

abstract：BACKGROUND:Myotonic dystrophy type 1 (MD1) is one of the most prevalent neuromuscular diseases, yet very little is known about how MD1 affects the lives of couples and how they themselves manage individually and together. To better match health care to their problems, concerns and needs, it is important to understand t...

journal_title：BMC neurology

authors： Cup EH,Kinébanian A,Satink T,Pieterse AJ,Hendricks HT,Oostendorp RA,van der Wilt GJ,van Engelen BG

更新日期：2011-07-13 00:00:00

abstract：BACKGROUND:Prediction of clinical outcome in the acute stage of ischaemic stroke can be difficult when based on patient characteristics, clinical findings and on non-contrast CT. CT perfusion and CT angiography may provide additional prognostic information and guide treatment in the early stage. We present the study pr...

journal_title：BMC neurology

authors： van Seeters T,Biessels GJ,van der Schaaf IC,Dankbaar JW,Horsch AD,Luitse MJ,Niesten JM,Mali WP,Kappelle LJ,van der Graaf Y,Velthuis BK,DUST investigators.

更新日期：2014-02-25 00:00:00

abstract：BACKGROUND:In the pathogenesis of limbic encephalitis other promoting factors besides the pure existence of autoantibodies are increasingly discussed to play a significant role. This is to our knowledge the first described patient in whom the presence of autoantibodies precedes the manifestation of limbic encephalitis ...

journal_title：BMC neurology

authors： Fauser S,Uttner I,Ariño H,Scherbaum WA,Saiz A,Lewerenz J

更新日期：2015-09-30 00:00:00