Structural connectivity in a paediatric case of anarchic hand syndrome.

Abstract:

BACKGROUND:"Anarchic hand" is a rare condition characterised by non-volitional, goal-directed movements of one arm. We report a case with analysis of structural and functional connectivity. CASE PRESENTATION:A 15 year old girl developed intermittent symptoms of intermanual conflict or anarchic hand as a result of traumatic brain injury during which she sustained a callosal bleed. Resting-state fMRI and DTI tractography were performed at a stage when symptoms had largely resolved. CONCLUSION:Structural connectivity between homologous superior frontal areas and functional connectivity between homologous posterior cingulate areas were significantly reduced, which may have contributed to causation. Tractography demonstrated new indirect connections between supplementary motor areas via the cerebellum, which we propose contributed to symptom resolution.

journal_name

BMC Neurol

journal_title

BMC neurology

authors

Basu AP,Taylor PN,Lowther E,Forsyth EO,Blamire AM,Forsyth RJ

doi

10.1186/s12883-015-0477-z

subject

Has Abstract

pub_date

2015-11-14 00:00:00

pages

234

issn

1471-2377

pii

10.1186/s12883-015-0477-z

journal_volume

15

pub_type

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