The relation between angioarchitectural factors of developmental venous anomaly and concomitant sporadic cavernous malformation.

abstract：BACKGROUND:Primary familial brain calcification is a rare autosomal dominant or recessive neurodegenerative disease, characterized by bilateral brain calcifications in different areas of the brain. It is a clinically heterogeneous disease and patients are reported to exhibit a wide spectrum of neurological and psychiat...

journal_title：BMC neurology

authors： Mathorne SW,Sørensen K,Fagerberg C,Bode M,Hertz JM

更新日期：2019-04-12 00:00:00

abstract：BACKGROUND:The coexistence of distinct neurodegenerative diseases in single cases has recently attracted greater attention. The phenotypic co-occurrence of progressive supranuclear palsy (PSP) and amyotrophic lateral sclerosis (ALS) has been documented in several cases. That said, the clinicopathological comorbidity of...

journal_title：BMC neurology

authors： Fujita K,Matsubara T,Miyamoto R,Sumikura H,Takeuchi T,Maruyama Saladini K,Kawarai T,Nodera H,Udaka F,Kume K,Morino H,Kawakami H,Hasegawa M,Kaji R,Murayama S,Izumi Y

更新日期：2019-07-18 00:00:00

abstract：BACKGROUND:Acute ischemic stroke attack with and without a recent TIA may differ in clinical risk factors, and this may affect treatment outcomes following thrombolytic therapy. We examined whether the odds of exclusion or inclusion for thrombolytic therapy are greater in ischemic stroke with TIA less than 24 h precedi...

journal_title：BMC neurology

authors： Poupore N,Strat D,Mackey T,Snell A,Nathaniel T

更新日期：2020-05-19 00:00:00

abstract：BACKGROUND:Tinnitus is a result of hyper-activity/hyper-synchrony of auditory neurons coding the tinnitus frequency, which has developed to synchronous mass activity owing the lack of inhibition. We assume that removal of exactly these frequency components from an auditory stimulus will cause the brain to reorganize ar...

journal_title：BMC neurology

authors： Pantev C,Rudack C,Stein A,Wunderlich R,Engell A,Lau P,Wollbrink A,Shaykevich A

更新日期：2014-03-02 00:00:00

abstract：BACKGROUND:This study aimed to determine the risk of thromboembolic events in patients with junctional bradycardia(JB). METHODS:We retrospectively reviewed electrocardiograms(ECGs) for 380,682 patients. Those with JB on an ECG at least twice over a ≥3-month interval were included for analysis. We additionally included...

journal_title：BMC neurology

authors： Kim GS,Uhm JS,Kim TH,Lee H,Park J,Park JK,Joung B,Pak HN,Lee MH

更新日期：2016-07-25 00:00:00

abstract：BACKGROUND:Post-stroke depression (PSD) is a mood disorder characterized by depression and anhedonia caused by stroke. Metabolomics identified metabolites associated with PSD, but previous studies are based on gas chromatography (GC)/mass spectrometry (MS). This study aimed to perform a liquid chromatography (LC)-MS-ba...

journal_title：BMC neurology

authors： Wang M,Gui X,Wu L,Tian S,Wang H,Xie L,Wu W

更新日期：2020-06-20 00:00:00

abstract：BACKGROUND:Road traffic accidents are known to be the main cause of traumatic brain injury (TBI). TBI is also a leading cause of death and disability. This study, by means of the idiographic approach (single-case experimental designs using multiple-baseline designs), has examined whether methylphenidate (MPH - trade na...

journal_title：BMC neurology

authors： Al-Adawi S,Al-Naamani A,Jaju S,Al-Farsi YM,Dorvlo ASS,Al-Maashani A,Al-Adawi SSH,Moustafa AA,Al-Sibani N,Essa MM,Burke DT,Qoronfleh MW

更新日期：2020-03-19 00:00:00

abstract：BACKGROUND:The study of muscle metabolism by near-infrared spectroscopy (NIRS) has been poorly implemented in multiple sclerosis (MS). Aims of the study were to compare resting muscle oxygen consumption (rmVO2) at gastrocnemius in MS patients and in age-matched healthy controls (HC) measured using NIRS, and to evaluate...

journal_title：BMC neurology

authors： Malagoni AM,Felisatti M,Lamberti N,Basaglia N,Manfredini R,Salvi F,Zamboni P,Manfredini F

更新日期：2013-05-29 00:00:00

abstract：BACKGROUND:The production of inflammatory cytokines resulting from amyloid β (Aβ) is associated with the initiation of Alzheimer's disease (AD). Atorvastatin (ATV) has been reported to improve AD, however, it is unclear how the anti-inflammatory mechanism is linked with its protection against the impairment of spatial ...

journal_title：BMC neurology

authors： Zhao L,Chen T,Wang C,Li G,Zhi W,Yin J,Wan Q,Chen L

更新日期：2016-02-04 00:00:00

abstract：BACKGROUND:Detecting malingering or exaggeration of impairments in brain function after traumatic brain injury is of increasing importance in neuropsychological assessment. Lawyers involved in brain injury litigation cases routinely coach their clients how to approach neuropsychological testing to their advantage. Thus...

journal_title：BMC neurology

authors： Rüsseler J,Brett A,Klaue U,Sailer M,Münte TF

更新日期：2008-10-07 00:00:00

abstract：BACKGROUND:Dopaminergic neuronal loss begins years before motor symptoms appear in Parkinson disease (PD). Thus, reliable biomarkers for early diagnosis and prognosis of PD are an essential pre-requisite to develop disease modifying therapies. Inflammation-derived oxidative stress is postulated to contribute to nigrost...

journal_title：BMC neurology

authors： Rathnayake D,Chang T,Udagama P

更新日期：2019-04-06 00:00:00

abstract：BACKGROUND:Facioscapulohumeral muscular dystrophy (FSHD) is a dominantly-inherited progressive muscular dystrophy caused by de-repression of the DUX4 gene, which causes disease by a toxic-gain-of-function. As molecularly targeted drugs move from preclinical testing into human trials, it is essential that we validate cl...

journal_title：BMC neurology

authors： LoRusso S,Johnson NE,McDermott MP,Eichinger K,Butterfield RJ,Carraro E,Higgs K,Lewis L,Mul K,Sacconi S,Sansone VA,Shieh P,van Engelen B,Wagner K,Wang L,Statland JM,Tawil R,ReSolve Investigators and the FSHD CTRN18.

更新日期：2019-09-10 00:00:00

abstract：BACKGROUND:Adrenomyeloneuropathy (AMN) is one of several phenotypes of the adrenoleukodystrophy spectrum caused by mutations in the ABCD1 gene on the X chromosome. An inflammatory component is part of the disease complex ranging from severe childhood CNS demyelination to spinal cord and peripheral nerve degeneration. ...

journal_title：BMC neurology

authors： Jønch AE,Danielsen ER,Thomsen C,Meden P,Svenstrup K,Nielsen JE

更新日期：2012-09-26 00:00:00

abstract：BACKGROUND:In this paper, seizure types, and epilepsy syndromes are elucidated as per ILAE (2010) classification. A brief outline of the antiepileptic drug regimens used and the outcome of seizure control in a two -year period is presented. The applicability of the ILAE classification in resource limited countries has ...

journal_title：BMC neurology

authors： Mohamed IN,Elseed MA,Mohamed S,Alsir A,Hamid EK,Omer IM,Elsadig SM,Gerais YM,Osman AH,Bakhiet AM,Hamed AA

更新日期：2019-11-15 00:00:00

abstract：BACKGROUND:Myasthenic crisis is the most serious life-threatening event in generalized myasthenia gravis (MG) patients. The objective of this study was to assess the long-term impact of thymectomy on rate and severity of these attacks in Iranian patients. METHODS:We reviewed the clinical records from 272 myasthenic pa...

journal_title：BMC neurology

authors： Soleimani A,Moayyeri A,Akhondzadeh S,Sadatsafavi M,Tavakoli Shalmani H,Soltanzadeh A

更新日期：2004-09-11 00:00:00

abstract：BACKGROUND:DNA methyltransferase 1 (EC 2.1.1.37), encoded by DNMT1 gene, is one of key enzymes in maintaining DNA methylation patterns of the human genome. It plays a crucial role in embryonic development, imprinting and genome stability, cell differentiation. The dysfunction of this group of enzymes can lead to a vari...

journal_title：BMC neurology

authors： Zheng W,Yan Z,He R,Huang Y,Lin A,Huang W,Su Y,Li S,Zhang VW,Xie H

更新日期：2018-10-20 00:00:00

abstract：BACKGROUND:MS-pathogenesis is known to involve both multiple environmental events, and several independent genetic risk-factors. METHODS:A model of susceptibility is developed and a mathematical analysis undertaken to elucidate the nature of genetic susceptibility to MS and to understand the constraints that are place...

journal_title：BMC neurology

authors： Goodin DS

更新日期：2010-10-28 00:00:00

abstract：BACKGROUND:Effective control of (upright) body posture requires a proper representation of body orientation. Stroke patients with pusher syndrome were shown to suffer from severely disturbed perception of own body orientation. They experience their body as oriented 'upright' when actually tilted by nearly 20 degrees to...

journal_title：BMC neurology

authors： Johannsen L,Broetz D,Karnath HO

更新日期：2006-08-23 00:00:00

abstract：BACKGROUND:Carotid rete mirabile (RM) is a meshwork of multiple, freely intercommunicating arterioles that reconstitute the absent or hypoplastic segments of the internal carotid artery (ICA). Carotid RM has been reported to be associated with cerebrovascular diseases. However, it is rarely associated with moyamoya-pat...

journal_title：BMC neurology

authors： Chen H,Hou K,Wang X,Xu K,Yu J

更新日期：2019-04-02 00:00:00

abstract：BACKGROUND:Association of leukoencephalopathy and atypical mycobacteriosis has been rarely reported. We present a case that is relevant for its unusual presentation and because it may shed further light on the pathogenic mechanisms underlying reversible encephalopathies. CASE REPORT:We report the case of a Hispanic 64...

journal_title：BMC neurology

authors： Oliveira MC,Sato DK,Soares-Neto HR,Lucato LT,Callegaro D,Nitrini R,Medeiros RS,Misu T,Fujihara K,Castro LH

更新日期：2015-09-02 00:00:00

abstract：BACKGROUND:Phase I/II placebo-controlled clinical trials of recombinant Factor VIIa (rFVIIa) suggested that administration of rFVIIa within 4 hours after onset of intracerebral hemorrhage (ICH) is safe, limits ICH growth, and improves outcomes. We sought to determine the cost-effectiveness of rFVIIa for acute ICH treat...

journal_title：BMC neurology

authors： Kissela BM,Eckman MH

更新日期：2008-05-19 00:00:00

abstract：BACKGROUND:Epidemiology of acute stroke in developing countries differs from that in the developed world, for example, the age at stroke, risk factors, subtypes of stroke and prognosis. Hypertension remains a dominant risk factor and prognostic indicator in patients with stroke in all communities. The risk of stroke is...

journal_title：BMC neurology

authors： Jain S,Namboodri KK,Kumari S,Prabhakar S

更新日期：2004-01-06 00:00:00

abstract：BACKGROUND:Common carotid artery occlusive disease (CCAOD) could form internal carotid artery steal pathways. Based on the diagnostic results of digital subtraction angiography (DSA), head and neck computed tomography angiography (CTA) was used to find the internal carotid artery stealing pathway after CCAOD. METHODS:...

journal_title：BMC neurology

authors： Wang D,Li Z,Zheng X,Cong H,Zhang T,Wang Z,Wang Y,He J

更新日期：2020-09-03 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea is a common sleep disorder in stroke patients. Obstructive sleep apnea is associated with stroke severity and poor functional outcome. Continuous positive airway pressure seems to improve functional recovery in stroke rehabilitation. To date, the effect of continuous positive airway p...

journal_title：BMC neurology

authors： Aaronson JA,van Bennekom CA,Hofman WF,van Bezeij T,van den Aardweg JG,Groet E,Kylstra WA,Schmand BA

更新日期：2014-02-25 00:00:00

abstract：BACKGROUND:Anterior spinal cord herniation (aSCH) is a rare cause of myelopathy which may present as pure motor syndrome and mimic other degenerative diseases of the spinal cord. In slowly progressive cases, diagnosis may be impeded by equivocal imaging results and mistaken for evolving upper motor neuron disease. As e...

journal_title：BMC neurology

authors： Regensburger M,Schlachetzki JCM,Klekamp J,Doerfler A,Winkler J

更新日期：2020-08-29 00:00:00

abstract：BACKGROUND:Neurogenic orthostatic hypotension (nOH) results from impaired vasoconstriction due to dysfunction of the autonomic nervous system and is commonly associated with Parkinson disease (PD), multiple system atrophy (MSA), and pure autonomic failure. nOH can increase the risk of falls due to symptoms that include...

journal_title：BMC neurology

authors： Claassen DO,Adler CH,Hewitt LA,Gibbons C

更新日期：2018-08-25 00:00:00

abstract：BACKGROUND:The X-linked form of Charcot-Marie-Tooth disease type 1 (CMTX1) is an inherited peripheral neuropathy that arises in patients with mutations in the gap-junction beta-1 gene (GJB1). CASE PRESENTATION:Three young male patients from Southern China with pes cavus experienced multiple episodes of transient centr...

journal_title：BMC neurology

authors： Liang Y,Liu J,Cheng D,Wu Y,Mo L,Huang W

更新日期：2019-12-16 00:00:00

abstract：BACKGROUND:Cerebral amyloid angiopathy (CAA) is characterized by the deposition of ß-amyloid peptides (Aß) in and surrounding the wall of microvasculature in the central nervous system, together with parenchymal amyloid plaques collectively referred to as cerebral amyloidosis, which occurs in the brain commonly among t...

journal_title：BMC neurology

authors： Li JM,Huang LL,Liu F,Tang BS,Yan XX

更新日期：2017-08-25 00:00:00

abstract：BACKGROUND:The study aims to assess the therapeutic benefits of motor imagery training in stroke patients with persistent motor weakness. There is evidence to suggest that mental rehearsal of movement can produce effects normally attributed to practising the actual movements. Imagining hand movements could stimulate th...

journal_title：BMC neurology

authors： Ietswaart M,Johnston M,Dijkerman HC,Scott CL,Joice SA,Hamilton S,Macwalter RS

更新日期：2006-10-26 00:00:00

abstract：BACKGROUND:Recent consensus guidelines recommend pregabalin as a first-tier treatment for painful diabetic peripheral neuropathy (DPN). We evaluated the efficacy of pregabalin 600 mg/d (300 mg dosed BID) versus placebo for relieving DPN-associated neuropathic pain, and assessed its safety using objective measures of ne...

journal_title：BMC neurology

authors： Arezzo JC,Rosenstock J,Lamoreaux L,Pauer L

更新日期：2008-09-16 00:00:00