Atorvastatin in improvement of cognitive impairments caused by amyloid β in mice: involvement of inflammatory reaction.

abstract：BACKGROUND:Seizures are one of the most important neurologic complications of human immuno-deficiency virus (HIV)-negative cryptococcal meningitis. A better understanding of the risk associated factors can help predict those who will require treatment. METHODS:This 22-year retrospective study enrolled 180 patients. Pr...

journal_title：BMC neurology

authors： Hung CW,Chang WN,Kung CT,Tsai NW,Wang HC,Lin WC,Huang CR,Huang CC,Tsai WC,Chang HW,Su YJ,Lin YJ,Cheng BC,Chang YT,Su CM,Lu CH

更新日期：2014-10-13 00:00:00

abstract：BACKGROUND:Spinal cord infarction (SCI) is rarely caused by vertebral artery dissection (VAD), which is an important cause of posterior circulation stroke in young and middle-aged patients. We report the case of a middle-aged patient without obvious risk factors for atherosclerosis who had SCI from right VAD. CASE PRE...

journal_title：BMC neurology

authors： Meng YY,Dou L,Wang CM,Kong DZ,Wei Y,Wu LS,Yang Y,Zhou HW

更新日期：2019-12-12 00:00:00

abstract：BACKGROUND:The clinical features of Alzheimer's disease (AD) are related to brain network degeneration, and hyperhomocysteinemia is related to greater white matter hyperintensities. We investigated the changes in four diffusion tensor imaging parameters in the white matter of patients with early stage AD, examined thei...

journal_title：BMC neurology

authors： Lee CC,Hsu SW,Huang CW,Chang WN,Chen SF,Wu MK,Chang CC,Hwang LC,Chen PC

更新日期：2017-10-06 00:00:00

abstract：BACKGROUND:Almost 40% of stroke patients have a poor outcome at 3 months after the index event. Predictors for stroke outcome in the early acute phase may help to tailor stroke treatment. Infection and inflammation are considered to influence stroke outcome. METHODS:In a prospective multicenter study in Germany and Sp...

journal_title：BMC neurology

authors： Mengel A,Ulm L,Hotter B,Harms H,Piper SK,Grittner U,Montaner J,Meisel C,Meisel A,Hoffmann S

更新日期：2019-07-03 00:00:00

abstract：BACKGROUND:Hemifacial atrophy (Parry-Romberg syndrome) is a relatively rare disease. The etiology of the disease is not clear. Some authors postulate its relation with limited scleroderma linearis. Linear scleroderma "en coup de sabre" is characterized by clinical presence of most commonly one-sided linear syndrome. In...

journal_title：BMC neurology

authors： Bergler-Czop B,Lis-Swiety A,Brzezińska-Wcisło L

更新日期：2009-07-27 00:00:00

abstract：BACKGROUND:While both hypercapnia and hypocapnia are harmful in patients with subarachnoid hemorrhage (SAH), it is unknown whether high-normal PaCO2 values are better than low-normal values. We hypothesized that high-normal PaCO2 values have more detrimental than beneficial effects on outcome. METHODS:Consecutive pati...

journal_title：BMC neurology

authors： Reiff T,Barthel O,Schönenberger S,Mundiyanapurath S

更新日期：2020-01-20 00:00:00

abstract：BACKGROUND:Women have been reported to show more frequent recanalization and better recovery after intravenous (IV) recombinant tissue plasminogen activator (rt-PA) treatment for acute stroke compared with men. To investigate this we studied a series of stroke patients receiving IV rt-PA and undergoing acute transcrani...

journal_title：BMC neurology

authors： Al-hussain F,Hussain MS,Molina C,Uchino K,Shuaib A,Demchuk AM,Alexandrov AV,Saqqur M,CLOTBUST Investigators.

更新日期：2014-03-26 00:00:00

abstract：BACKGROUND:In Asia, stroke incidence varies dramatically from country to country. Little is known about stroke incidence in Asians/Pacific Islanders in the US, where regional heterogeneity in Asian/Pacific Islander sub-populations is great. We sought to characterize both the national and regional incidences of first an...

journal_title：BMC neurology

authors： Nguyen-Huynh MN,Johnston SC

更新日期：2005-11-10 00:00:00

abstract：BACKGROUND:Dorsolateral medullary infarction (Wallenberg syndrome) is rare in clinical practice; however, the subsequent corneal lesions are more uncommon. To our knowledge, only one such case was previously reported. We report a similar case with successful treatment and recovery, and analyse both cases to address the...

journal_title：BMC neurology

authors： Wu S,Li N,Xia F,Sidlauskas K,Lin X,Qian Y,Gao W,Zhang Q

更新日期：2014-12-04 00:00:00

abstract：:The term paraproteinemic neuropathy describes a heterogeneous set of neuropathies characterized by the presence of homogeneous immunoglobulin in the serum. An abnormal clonal proliferation of B-lymphocytes or plasma cells, which may or may not occur in the context of a hematologic malignancy, produces the immunoglobul...

journal_title：BMC neurology

authors： Rison RA,Beydoun SR

更新日期：2016-01-28 00:00:00

abstract：BACKGROUND:Stroke represents one of the most costly and long-term disabling conditions in adulthood worldwide and there is a need to determine the effectiveness of rehabilitation programs in the late phase after stroke. Limited scientific support exists for training incorporating rhythm and music as well as therapeutic...

journal_title：BMC neurology

authors： Bunketorp Käll L,Lundgren-Nilsson Å,Blomstrand C,Pekna M,Pekny M,Nilsson M

更新日期：2012-11-21 00:00:00

abstract：BACKGROUND:The purpose of this study was to examine the prevalence of sleep problems in a community-based sample of patients with Parkinson's disease (PD) in Norway, and their associated factors. METHODS:176 consecutive PD outpatients (41% females) were included in a study of non-motor symptoms, including sleep proble...

journal_title：BMC neurology

authors： Svensson E,Beiske AG,Loge JH,Beiske KK,Sivertsen B

更新日期：2012-08-10 00:00:00

abstract：BACKGROUND:Chronic headache (headache ≥ 15 days/month for at least 3 months) affects 2-5% of the general population. Medication overuse contributes to the problem. Medication-overuse headache (MOH) can be identified by using the Severity of Dependence Scale (SDS). A "brief intervention" scheme (BI) has previously been ...

journal_title：BMC neurology

authors： Kristoffersen ES,Straand J,Benth JS,Russell MB,Lundqvist C

更新日期：2012-08-10 00:00:00

abstract：BACKGROUND:Cognitive impairment commonly occurs in the acute phase post-stroke, but may persist with over half of all stroke survivors experiencing some form of long-term cognitive deficit. Recent evidence suggests that optimising secondary prevention adherence is a critical factor in preventing recurrent stroke and th...

journal_title：BMC neurology

authors： Mellon L,Brewer L,Hall P,Horgan F,Williams D,Hickey A,ASPIRE-S study group.

更新日期：2015-03-12 00:00:00

abstract：BACKGROUND:Although the precise etiology of multiple sclerosis is largely unknown, there is some speculation that a prior history of surgery may be associated with the subsequent risk for developing the disease. Therefore, we aimed to examine surgery as a risk factor for the diagnosis of multiple sclerosis. METHODS:We...

journal_title：BMC neurology

authors： Lunny C,Knopp-Sihota JA,Fraser SN

更新日期：2013-05-06 00:00:00

abstract：BACKGROUND:Only a few case reports and case series dealing with oral and dental health care are available in literature until now. The aim of the present pilot study was to determine the status of dental health in comparison to matched controls and to heighten the neurologists' and dentists' awareness of the oral aspec...

journal_title：BMC neurology

authors： Saft C,Andrich JE,Müller T,Becker J,Jackowski J

更新日期：2013-09-03 00:00:00

abstract：BACKGROUND:To evaluate the relationship between the flow signal intensity of branch arteries distal to the stenosis on 3-dimensional (3D) time-of-flight (TOF) magnetic resonance angiography (MRA) and the risk of stroke recurrence in patients with severe middle cerebral artery (MCA) trunk stenosis. METHODS:We prospecti...

journal_title：BMC neurology

authors： Chen H,Li Z,Hong H,Xing S,Liu G,Zhang A,Tan S,Zhang J,Zeng J

更新日期：2015-09-16 00:00:00

abstract：BACKGROUND:This study aims to investigate the clinical value of two kinds of vestibular-evoked myogenic potentials in patients with sudden sensorineural hearing loss (SSNHL). METHODS:A total of 82 patients were divided into two groups: vertigo group and non-vertigo group. All patients underwent examinations for pure t...

journal_title：BMC neurology

authors： Wang Y,Gu ST,Bao XL,Guo JL

更新日期：2019-12-21 00:00:00

abstract：BACKGROUND:Horizontal gaze palsy with progressive scoliosis (HGPPS) is a rare autosomal recessive congenital anomaly characterized by horizontal gaze limitation and progressive scoliosis. We investigated the underlying pathogenesis by incorporating diffusion tensor imaging and an electrophysiological study. CASE PRESE...

journal_title：BMC neurology

authors： Lin CW,Lo CP,Tu MC

更新日期：2018-05-29 00:00:00

abstract：BACKGROUND:The use of vestibular rehabilitation principles in the management of gaze and postural stability impairments in people with multiple sclerosis (PwMS) has shown promise in pilot work completed in our lab and in a recently published randomized clinical trial (RCT). However, further work is needed to fully quan...

journal_title：BMC neurology

authors： Loyd BJ,Fangman A,Peterson DS,Gappmaier E,Schubert MC,Thackery A,Dibble L

更新日期：2019-06-10 00:00:00

abstract：BACKGROUND:Common carotid artery occlusive disease (CCAOD) could form internal carotid artery steal pathways. Based on the diagnostic results of digital subtraction angiography (DSA), head and neck computed tomography angiography (CTA) was used to find the internal carotid artery stealing pathway after CCAOD. METHODS:...

journal_title：BMC neurology

authors： Wang D,Li Z,Zheng X,Cong H,Zhang T,Wang Z,Wang Y,He J

更新日期：2020-09-03 00:00:00

abstract：BACKGROUND:Chronic low back pain (CLBP) has been shown to be associated with various pathophysiological changes at several level of the sensorimotor system, pointing to a general hypersensitivity in CLBP patients. The aim of the present study was to investigate signs of generalized mechanical pain hypersensitivity in C...

journal_title：BMC neurology

authors： Puta C,Schulz B,Schoeler S,Magerl W,Gabriel B,Gabriel HH,Miltner WH,Weiss T

更新日期：2012-09-21 00:00:00

abstract：BACKGROUND:Multiple sclerosis is a chronic, incurable, demyelinating disease that requires long-term treatment. Rates of non-adherence to prescribed therapy of up to 50% have been reported for chronic diseases. Strategies to improve treatment adherence are therefore of the utmost importance. This study will evaluate th...

journal_title：BMC neurology

authors： Zettl UK,Bauer-Steinhusen U,Glaser T,Hechenbichler K,Limmroth V,Study Group.

更新日期：2013-09-06 00:00:00

abstract：BACKGROUND:Decision-making is an essential function of everyday life. Decision-making under explicit risk requires developing advantageous decision strategies based on fixed outcomes (e.g., probabilities of winning or losing a bet). Decision-making and its neural substrates have been rarely studied in MS. We expected p...

journal_title：BMC neurology

authors： Radomski AD,Power C,Purdon SE,Emery DJ,Blevins G,Warren KG,Fujiwara E

更新日期：2015-04-23 00:00:00

abstract：BACKGROUND:Autonomic nervous system (ANS) dysfunction is present in up to one third of patients with tetanus. The prognostic value of ANS dysfunction is known in severe tetanus but its value is not well established in mild to moderate tetanus. METHODS:Medical records of all patients admitted with tetanus at two academ...

journal_title：BMC neurology

authors： Wasay M,Khealani BA,Talati N,Shamsi R,Syed NA,Salahuddin N

更新日期：2005-01-31 00:00:00

abstract：BACKGROUND:Our objective was to find which additional factors can influence the favorable result in stroke patients after receiving fibrinolytic and/or endovascular treatment, quantified as a more than 30% improvement of the NIHSS score at 7 days. METHODS:This is a retrospective study to find factors that could influe...

journal_title：BMC neurology

authors： Tudor R,Iovanescu G,Reisz D,Cornea A,Potre-Oncu C,Tutelca A,Simu M

更新日期：2020-11-14 00:00:00

abstract：BACKGROUND:This study aimed to determine the risk of thromboembolic events in patients with junctional bradycardia(JB). METHODS:We retrospectively reviewed electrocardiograms(ECGs) for 380,682 patients. Those with JB on an ECG at least twice over a ≥3-month interval were included for analysis. We additionally included...

journal_title：BMC neurology

authors： Kim GS,Uhm JS,Kim TH,Lee H,Park J,Park JK,Joung B,Pak HN,Lee MH

更新日期：2016-07-25 00:00:00

abstract：BACKGROUND:The etiologic determinants of stroke in young adults remain a diagnostic challenge in up to one-fourth of cases. Increasing evidences led to consider Fabry's disease (FD) as a possible cause to check up. We aimed at evaluating the prevalence of unrecognized FD in a cohort of patients with juvenile stroke in ...

journal_title：BMC neurology

authors： Fancellu L,Borsini W,Romani I,Pirisi A,Deiana GA,Sechi E,Doneddu PE,Rassu AL,Demurtas R,Scarabotto A,Cassini P,Arbustini E,Sechi G

更新日期：2015-12-12 00:00:00

abstract：BACKGROUND:Detecting and treating neuropsychological deficits after aneurysmatic subarachnoid hemorrhage (aSAH) play a key role in regaining independence; however, detecting deficits relevant to social and professional reintegration has been difficult and optimal timing of assessments remains unclear. Therefore, we eva...

journal_title：BMC neurology

authors： Walter J,Grutza M,Vogt L,Unterberg A,Zweckberger K

更新日期：2020-11-26 00:00:00

abstract：BACKGROUND:Vascular cognitive impairment-no dementia (VCIND) refers to the early or mild cognitive impairment induced by cerebral vascular injury. Research shows that serum total homocysteine (tHcy) level is an independent risk factor for cerebral vascular disease and may be closely related to cognitive function.Curren...

journal_title：BMC neurology

authors： Jiang B,Chen Y,Yao G,Yao C,Zhao H,Jia X,Zhang Y,Ge J,Qiu E,Ding C

更新日期：2014-11-30 00:00:00