Enhanced sensitivity to punctate painful stimuli in female patients with chronic low back pain.

abstract：BACKGROUND:Clinical trials are the hallmark of evidence-based medicine, but recruitment is often challenging, especially in stroke trials investigating patients not being able to give informed consent. In some nations, ethics committees will not approve of inclusion in a clinical study via consent of a legal representa...

journal_title：BMC neurology

authors： Hotter B,Ulm L,Hoffmann S,Katan M,Montaner J,Bustamante A,Meisel A

更新日期：2017-12-04 00:00:00

abstract：BACKGROUND:Gall bladder cancer (GBC) is associated with abdominal pain, lump, nausea, vomiting, and jaundice due to either gall bladder mass or the involved adjacent peritoneal structures. Gall bladder cancer presenting as refractory epilepsy is rare. Here we report a young female GBC patient who presented with an atyp...

journal_title：BMC neurology

authors： Pandey S,Garg RK,Malhotra HS,Uniyal R,Kumar N

更新日期：2019-05-10 00:00:00

abstract：BACKGROUND:Epilepsy is a major complication of stroke. We aimed to establish whether there is an association between intravenous thrombolysis, intra-arterial thrombolysis and post stroke seizure (PSS) development. Improved understanding of the relationship between reperfusion therapies and seizure development may impro...

journal_title：BMC neurology

authors： Naylor J,Thevathasan A,Churilov L,Guo R,Xiong Y,Koome M,Chen Z,Chen Z,Liu X,Kwan P,Campbell BCV

更新日期：2018-05-03 00:00:00

abstract：BACKGROUND:In this paper, seizure types, and epilepsy syndromes are elucidated as per ILAE (2010) classification. A brief outline of the antiepileptic drug regimens used and the outcome of seizure control in a two -year period is presented. The applicability of the ILAE classification in resource limited countries has ...

journal_title：BMC neurology

authors： Mohamed IN,Elseed MA,Mohamed S,Alsir A,Hamid EK,Omer IM,Elsadig SM,Gerais YM,Osman AH,Bakhiet AM,Hamed AA

更新日期：2019-11-15 00:00:00

abstract：BACKGROUND:Mild cognitive impairment (MCI), defined as a transitional zone between normal cognition and dementia, requires a battery of formal neuropsychological tests administered by a trained rater for its diagnosis. The objective of this study was to develop a screening tool for MCI. METHODS:One hundred ninety seve...

journal_title：BMC neurology

authors： Guo QH,Zhou B,Zhao QH,Wang B,Hong Z

更新日期：2012-10-11 00:00:00

abstract：:The term paraproteinemic neuropathy describes a heterogeneous set of neuropathies characterized by the presence of homogeneous immunoglobulin in the serum. An abnormal clonal proliferation of B-lymphocytes or plasma cells, which may or may not occur in the context of a hematologic malignancy, produces the immunoglobul...

journal_title：BMC neurology

authors： Rison RA,Beydoun SR

更新日期：2016-01-28 00:00:00

abstract：BACKGROUND:Detecting and treating neuropsychological deficits after aneurysmatic subarachnoid hemorrhage (aSAH) play a key role in regaining independence; however, detecting deficits relevant to social and professional reintegration has been difficult and optimal timing of assessments remains unclear. Therefore, we eva...

journal_title：BMC neurology

authors： Walter J,Grutza M,Vogt L,Unterberg A,Zweckberger K

更新日期：2020-11-26 00:00:00

abstract：BACKGROUND:In adults, the anastomosis between carotid and vertebrobasilar arteries is usually the posterior communicating artery, sometimes the primitive trigeminal artery. In this case, the basilar artery fed the internal carotid artery through the pontine-to-tentorial artery anastomosis after severe stenosis from tra...

journal_title：BMC neurology

authors： Liu X,Li B,Liu Y,Wu H,Zhang H,Dou L,Liu C

更新日期：2020-03-17 00:00:00

abstract：BACKGROUND:Recent studies suggest that epigenetic factors may play an important role in the pathogenesis of Parkinson's disease (PD). In our previous work, we sequenced the exomes of sixteen patients from eight Chinese PD families using whole exome sequencing technology, consequently three patients from different pedig...

journal_title：BMC neurology

authors： Liao XX,Zhan ZX,Luo YY,Li K,Wang JL,Guo JF,Yan XX,Xia K,Tang BS,Shen L

更新日期：2013-12-11 00:00:00

abstract：BACKGROUND:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a clinically heterogeneous disorder characterized by epileptic seizures, psychosis, dyskinesia, consciousness impairments, and autonomic instability. Symptoms are always various. Sometimes it presents in milder or incomplete forms. We report 4 cases ...

journal_title：BMC neurology

authors： Qin K,Wu W,Huang Y,Xu D,Zhang L,Zheng B,Jiang M,Kou C,Gao J,Li W,Zhang J,Wang S,Luan Y,Yan C,Xu D,Zheng X

更新日期：2017-01-05 00:00:00

abstract：BACKGROUND:To describe the clinical phenotype of paroxysmal extreme pain disorder, an autosomal dominant condition in four members in one family with the mutation NM_002977.3:c.3892G > T (p.Val1298Phe) in the SCN9A gene. Clinical examinations and details from members of one Polish family were collected, including age a...

journal_title：BMC neurology

authors： Stępień A,Sałacińska D,Staszewski J,Durka-Kęsy M,Dobrogowski J

更新日期：2020-05-13 00:00:00

abstract：BACKGROUND:While both hypercapnia and hypocapnia are harmful in patients with subarachnoid hemorrhage (SAH), it is unknown whether high-normal PaCO2 values are better than low-normal values. We hypothesized that high-normal PaCO2 values have more detrimental than beneficial effects on outcome. METHODS:Consecutive pati...

journal_title：BMC neurology

authors： Reiff T,Barthel O,Schönenberger S,Mundiyanapurath S

更新日期：2020-01-20 00:00:00

abstract：BACKGROUND:Patients with multiple sclerosis (MS) have a decreased frequency of CD8+ T cells reactive to their own Epstein-Barr virus (EBV) infected B cells. We have proposed that this might predispose to the development of MS by allowing EBV-infected autoreactive B cells to accumulate in the central nervous system. The...

journal_title：BMC neurology

authors： Pender MP,Csurhes PA,Pfluger CM,Burrows SR

更新日期：2011-08-03 00:00:00

abstract：BACKGROUND:Headache is a common complaint in children and adolescents. Recently, an increased prevalence of headache in children and adolescents has been reported. METHODS:We retrospectively reviewed the medical records of children and adolescents attending the Headache Clinic of Daejeon St. Mary's Hospital during the...

journal_title：BMC neurology

authors： Jeong YJ,Lee YT,Lee IG,Han JY

更新日期：2018-05-21 00:00:00

abstract：BACKGROUND:Late-onset multiple acyl-CoA dehydrogenase deficiency (MADD) is an autosomal recessive inherited disease of metabolic dysfunction clinically characterized by fluctuating proximal muscle weakness, excise intolerance, and dramatic riboflavin responsiveness. Dropped head syndrome can occasionally be observed in...

journal_title：BMC neurology

authors： Peng Y,Zhu M,Zheng J,Zhu Y,Li X,Wei C,Hong D

更新日期：2015-07-24 00:00:00

abstract：BACKGROUND:Elevated intracranial pressure from cerebral edema is the major cause of early mortality in acute stroke. Current treatment strategies to limit cerebral edema are not particularly effective. Some novel anti-edema measures have shown promising early findings in experimental stroke models. Vasopressin antagoni...

journal_title：BMC neurology

authors： Hedna VS,Bidari S,Gubernick D,Ansari S,Satriotomo I,Khan AA,Qureshi AI

更新日期：2014-11-18 00:00:00

abstract：BACKGROUND:Postherpetic neuralgia (PHN) is a painful and difficult to treat complication of acute herpes zoster. Current treatment options provide only partial relief and are often limited by poor tolerability. We evaluated the safety and efficacy of a single 60-minute application of NGX-4010, an 8% capsaicin patch, in...

journal_title：BMC neurology

authors： Webster LR,Tark M,Rauck R,Tobias JK,Vanhove GF

更新日期：2010-10-11 00:00:00

abstract：BACKGROUND:Complaints of unrefreshing sleep are a prominent component of chronic fatigue syndrome (CFS); yet, polysomnographic studies have not consistently documented sleep abnormalities in CFS patients. We conducted this study to determine whether alterations in objective sleep characteristics are associated with sub...

journal_title：BMC neurology

authors： Majer M,Jones JF,Unger ER,Youngblood LS,Decker MJ,Gurbaxani B,Heim C,Reeves WC

更新日期：2007-12-05 00:00:00

abstract：BACKGROUND:An Early Supported Discharge (ESD) and rehabilitation from a coordinated team in the home environment is recommended in several high-income countries for patients with mild to moderate symptoms after stroke. Returning home from the hospital takes place very early in Sweden today (12 days post stroke), thus t...

journal_title：BMC neurology

authors： Nordin Å,Sunnerhagen KS,Axelsson ÅB

更新日期：2015-11-16 00:00:00

abstract：BACKGROUND:Machado-Joseph disease (MJD), or spinocerebellar ataxia type 3 (SCA3), is an autosomal dominant neurodegenerative disorder of late onset, which is caused by a CAG repeat expansion in the coding region of the ATXN3 gene. This disease presents clinical heterogeneity, which cannot be completely explained by the...

journal_title：BMC neurology

authors： Bettencourt C,Santos C,Coutinho P,Rizzu P,Vasconcelos J,Kay T,Cymbron T,Raposo M,Heutink P,Lima M

更新日期：2011-10-24 00:00:00

abstract：BACKGROUND:A Transient Ischaemic Attack (TIA) bears a high risk of a subsequent ischaemic stroke. Adequate diagnosis of a TIA should be followed immediately by the start of appropriate preventive therapy, including antiplatelets. The diagnosis of a TIA based on symptoms and signs only is notoriously difficult and bioma...

journal_title：BMC neurology

authors： Dolmans LS,Rutten FH,El Bartelink ML,Seppenwoolde G,van Delft S,Kappelle LJ,Hoes AW

更新日期：2015-07-28 00:00:00

abstract：BACKGROUND:Muscle fibrosis characterizes degenerated muscles in muscular dystrophies and in late onset myopathies. Fibrotic muscles often exhibit thickening of the extracellular matrix (ECM). The molecular regulation of this process is not fully understood. In oculopharyngeal muscular dystrophy (OPMD), an expansion of ...

journal_title：BMC neurology

authors： Raz V,Sterrenburg E,Routledge S,Venema A,van der Sluijs BM,Trollet C,Dickson G,van Engelen BG,van der Maarel SM,Antoniou MN

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Previous epidemiologic studies have examined the association of smoking with amyotrophic lateral sclerosis (ALS) incidence, but their results have been inconsistent. Moreover, limited information exists on the association between smoking and survival in ALS patients. We evaluated the association of smoking w...

journal_title：BMC neurology

authors： Alonso A,Logroscino G,Jick SS,Hernán MA

更新日期：2010-01-14 00:00:00

abstract：BACKGROUND:There is conflicting information as to whether antiretroviral drugs with better central nervous system (CNS) penetration (neuroHAART) assist in improving neurocognitive function and suppressing cerebrospinal fluid (CSF) HIV RNA. The current review aims to better synthesise existing literature by using an inn...

journal_title：BMC neurology

authors： Cysique LA,Waters EK,Brew BJ

更新日期：2011-11-22 00:00:00

abstract：BACKGROUND:B-mode and Color Doppler ultrasonography (CDUS) are the methods of choice for screening and determining the degree of Carotid artery stenosis. The evaluation of stenosis with calcification may be hampered by a common CDUS artifact known as acoustic shadow (AS). Our objective was to assess the change in relia...

journal_title：BMC neurology

authors： Seyman EE,Bornstein N,Auriel E,Cohen O,Nissel T,Hallevi H

更新日期：2019-07-29 00:00:00

abstract：:An international expert consensus committee recently recommended a brief battery of tests for cognitive evaluation in multiple sclerosis. The Brief International Cognitive Assessment for MS (BICAMS) battery includes tests of mental processing speed and memory. Recognizing that resources for validation will vary intern...

journal_title：BMC neurology

authors： Benedict RH,Amato MP,Boringa J,Brochet B,Foley F,Fredrikson S,Hamalainen P,Hartung H,Krupp L,Penner I,Reder AT,Langdon D

更新日期：2012-07-16 00:00:00

abstract：BACKGROUND:Intracranial hemorrhage in central nervous system lymphoma is extremely rare. T2*-weighted gradient-echo magnetic resonance imaging is of particularly use in detecting silent hemorrhage as hypointense signals due to the deposition of paramagnetic hemosiderin or mineralization. Multifocal hemosiderin depositi...

journal_title：BMC neurology

authors： Yang XZ,Ni J,Cui LY

更新日期：2014-09-25 00:00:00

abstract：BACKGROUND:Dementia has been associated with an increased risk of hip fracture. However, little research has been conducted on the impact of dementia on wrist or vertebral fracture development. The aim of this study was to investigate whether dementia is a risk factor for different types of fracture in Taiwan. METHODS...

journal_title：BMC neurology

authors： Wang HK,Hung CM,Lin SH,Tai YC,Lu K,Liliang PC,Lin CW,Lee YC,Fang PH,Chang LC,Li YC

更新日期：2014-09-12 00:00:00

abstract：BACKGROUND:Multiple pathogenic factors may contribute to the pathophysiology of Alzheimer's disease (AD). Peripheral blood markers have been used to assess biochemical changes associated with AD and mild cognitive impairment (MCI) and involved in their pathophysiology. METHODS:Plasma samples and clinical data were obt...

journal_title：BMC neurology

authors： Kim SM,Song J,Kim S,Han C,Park MH,Koh Y,Jo SA,Kim YY

更新日期：2011-05-12 00:00:00

abstract：BACKGROUND:Tinnitus is a result of hyper-activity/hyper-synchrony of auditory neurons coding the tinnitus frequency, which has developed to synchronous mass activity owing the lack of inhibition. We assume that removal of exactly these frequency components from an auditory stimulus will cause the brain to reorganize ar...

journal_title：BMC neurology

authors： Pantev C,Rudack C,Stein A,Wunderlich R,Engell A,Lau P,Wollbrink A,Shaykevich A

更新日期：2014-03-02 00:00:00