Abstract:
BACKGROUND:Gall bladder cancer (GBC) is associated with abdominal pain, lump, nausea, vomiting, and jaundice due to either gall bladder mass or the involved adjacent peritoneal structures. Gall bladder cancer presenting as refractory epilepsy is rare. Here we report a young female GBC patient who presented with an atypical and refractory frontal lobe seizures as the first manifestation of gall bladder cancer. CASE PRESENTATION:A 46 years young female presented first time to the hospital with uncontrolled seizures and headache in 5 months duration. Seizures were very atypical in semiology with ptosis and mydriasis to either side along with ipsilateral ocular deviation. The episodes were bilateral but right eyelid ptosis, mydriasis and right horizontal conjugate deviation were frequent. MRI brain showed encephalomalacia in the left frontal region on axial T2 and coronal T1 weighted images without any enhancement on gadolinium contrast. CECT abdomen revealed a heterogeneously enhancing gall bladder mass with the evidence of lung metastasis from chest CT scan. CSF for malignant cytology was negative. Seizures were refractory to the treatment. CONCLUSION:Though CNS involvement is uncommon but it can be the only presentation in gall bladder cancer.
journal_name
BMC Neuroljournal_title
BMC neurologyauthors
Pandey S,Garg RK,Malhotra HS,Uniyal R,Kumar Ndoi
10.1186/s12883-019-1318-2subject
Has Abstractpub_date
2019-05-10 00:00:00pages
95issue
1issn
1471-2377pii
10.1186/s12883-019-1318-2journal_volume
19pub_type
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