Co-morbidity of progressive supranuclear palsy and amyotrophic lateral sclerosis: a clinical-pathological case report.

abstract：BACKGROUND:Multiple sclerosis is a chronic, incurable, demyelinating disease that requires long-term treatment. Rates of non-adherence to prescribed therapy of up to 50% have been reported for chronic diseases. Strategies to improve treatment adherence are therefore of the utmost importance. This study will evaluate th...

journal_title：BMC neurology

authors： Zettl UK,Bauer-Steinhusen U,Glaser T,Hechenbichler K,Limmroth V,Study Group.

更新日期：2013-09-06 00:00:00

abstract：BACKGROUND:Limb Girdle Muscular Dystrophy (LGMD), caused by defective α-dystroglycan (α-DG) glycosylation, was recently associated with mutations in Isoprenoid synthase domain-containing (ISPD) and GDP-mannose pyrophosphorylase B (GMPPB) genes. The frequency of ISPD and GMPPB gene mutations in the LGMD population is un...

journal_title：BMC neurology

authors： Magri F,Colombo I,Del Bo R,Previtali S,Brusa R,Ciscato P,Scarlato M,Ronchi D,D'Angelo MG,Corti S,Moggio M,Bresolin N,Comi GP

更新日期：2015-09-24 00:00:00

abstract：BACKGROUND:It has been recently demonstrated that in Frontotemporal Lobar Degeneration (FTLD) memory deficits at presentation are commoner than previously thought. Apolipoprotein E (ApoE) genotype, the major genetic risk factor in sporadic late-onset Alzheimer Disease (AD), modulates cerebral perfusion in late middle-a...

journal_title：BMC neurology

authors： Borroni B,Perani D,Archetti S,Agosti C,Paghera B,Bellelli G,Di Luca M,Padovani A

更新日期：2006-08-24 00:00:00

abstract：BACKGROUND:The etiologic determinants of stroke in young adults remain a diagnostic challenge in up to one-fourth of cases. Increasing evidences led to consider Fabry's disease (FD) as a possible cause to check up. We aimed at evaluating the prevalence of unrecognized FD in a cohort of patients with juvenile stroke in ...

journal_title：BMC neurology

authors： Fancellu L,Borsini W,Romani I,Pirisi A,Deiana GA,Sechi E,Doneddu PE,Rassu AL,Demurtas R,Scarabotto A,Cassini P,Arbustini E,Sechi G

更新日期：2015-12-12 00:00:00

abstract：BACKGROUND:Susac syndrome (SuS) is a rare condition characterized by a clinical triad of sensorineural hearing loss, branch artery occlusion and encephalopathy. This study reports an increased incidence of SuS in Israel. We describe the clinical characteristics of these patients, diagnostic procedures and the use and s...

journal_title：BMC neurology

authors： Wilf-Yarkoni A,Elkayam O,Aizenstein O,Oron Y,Furer V,Zur D,Goldstein M,Barequet D,Hallevi H,Karni A,Habot-Wilner Z,Regev K

更新日期：2020-09-02 00:00:00

abstract：BACKGROUND:"Anarchic hand" is a rare condition characterised by non-volitional, goal-directed movements of one arm. We report a case with analysis of structural and functional connectivity. CASE PRESENTATION:A 15 year old girl developed intermittent symptoms of intermanual conflict or anarchic hand as a result of trau...

journal_title：BMC neurology

authors： Basu AP,Taylor PN,Lowther E,Forsyth EO,Blamire AM,Forsyth RJ

更新日期：2015-11-14 00:00:00

abstract：BACKGROUND:Human serum paraoxonase 1 (PON1) plays a major role in the metabolism of several organophosphorus compounds. The enzyme is encoded by the polymorphic gene PON1, located on chromosome 7q21.3. Aiming to identify genetic variations related to the risk of developing brain tumors, we investigated the putative ass...

journal_title：BMC neurology

authors： Martínez C,Molina JA,Alonso-Navarro H,Jiménez-Jiménez FJ,Agúndez JA,García-Martín E

更新日期：2010-08-19 00:00:00

abstract：BACKGROUND:The number of patients suffering post-stroke seizure after ischemic stroke (PSSi) is quite considerable, especially because ischemic stroke is more prevalent than hemorrhage in the general population. This study aimed to determine the predicting factors for seizure recurrence in ischemic stroke survivors and...

journal_title：BMC neurology

authors： Kim HJ,Park KD,Choi KG,Lee HW

更新日期：2016-11-05 00:00:00

abstract：BACKGROUND:Neuromuscular electrical stimulation (NMES) is commonly used to activate skeletal muscles and reverse muscle atrophy in clinical populations. Clinical recommendations for NMES suggest the use of short pulse widths (100-200 μs) and low-to-moderate pulse frequencies (30-50 Hz). However, this type of NMES cause...

journal_title：BMC neurology

authors： Bochkezanian V,Newton RU,Trajano GS,Vieira A,Pulverenti TS,Blazevich AJ

更新日期：2017-05-02 00:00:00

abstract：BACKGROUND:The disease burden of human immunodeficiency virus (HIV)--acquired immunodeficiency syndrome (AIDS) is highest in sub-Saharan Africa but there are few studies on the associated neurocognitive disorders in this region. The objectives of this study were to determine whether Western neuropsychological (NP) meth...

journal_title：BMC neurology

authors： Kanmogne GD,Kuate CT,Cysique LA,Fonsah JY,Eta S,Doh R,Njamnshi DM,Nchindap E,Franklin DR Jr,Ellis RJ,McCutchan JA,Binam F,Mbanya D,Heaton RK,Njamnshi AK

更新日期：2010-07-13 00:00:00

abstract：BACKGROUND:Only a few case reports and case series dealing with oral and dental health care are available in literature until now. The aim of the present pilot study was to determine the status of dental health in comparison to matched controls and to heighten the neurologists' and dentists' awareness of the oral aspec...

journal_title：BMC neurology

authors： Saft C,Andrich JE,Müller T,Becker J,Jackowski J

更新日期：2013-09-03 00:00:00

abstract：BACKGROUND:In Asia, stroke incidence varies dramatically from country to country. Little is known about stroke incidence in Asians/Pacific Islanders in the US, where regional heterogeneity in Asian/Pacific Islander sub-populations is great. We sought to characterize both the national and regional incidences of first an...

journal_title：BMC neurology

authors： Nguyen-Huynh MN,Johnston SC

更新日期：2005-11-10 00:00:00

abstract：BACKGROUND:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a clinically heterogeneous disorder characterized by epileptic seizures, psychosis, dyskinesia, consciousness impairments, and autonomic instability. Symptoms are always various. Sometimes it presents in milder or incomplete forms. We report 4 cases ...

journal_title：BMC neurology

authors： Qin K,Wu W,Huang Y,Xu D,Zhang L,Zheng B,Jiang M,Kou C,Gao J,Li W,Zhang J,Wang S,Luan Y,Yan C,Xu D,Zheng X

更新日期：2017-01-05 00:00:00

abstract：BACKGROUND:Osteogenesis imperfecta (OI) is a heterogeneous group of inherited disorders that occur owing to the abnormalities in type 1 collagen, and is characterized by increased bone fragility and other extraskeletal manifestations. We report the case of a patient who was diagnosed with OI following subarachnoid hemo...

journal_title：BMC neurology

authors： Hirohata T,Miyawaki S,Mizutani A,Iwakami T,Yamada S,Nishido H,Suzuki Y,Miyamoto S,Hoya K,Murakami M,Matsuno A

更新日期：2014-07-23 00:00:00

abstract：BACKGROUND:Overweight is reported as a side effect of SDR. The aims were to study the development of weight, height and body mass index (BMI) during five years after SDR. METHODS:This prospective, longitudinal and practice-based study included all 56 children with CP spastic diplegia undergoing SDR from the start in M...

journal_title：BMC neurology

authors： Westbom L,Lundkvist Josenby A,Wagner P,Nordmark E

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Dorsolateral medullary infarction is a typical cerebral infarction which is characterized by Wallenberg's syndrome. Neurotrophic keratopathy is an uncommon consequence of dorsolateral medullary infarction. At present, the protocol is aimed to study the dynamic changes in corneal innervation and the ocular su...

journal_title：BMC neurology

authors： Wang J,Liu P,Liu Z,Tian Y,Zhang G,Guo J,Li L,Liu Z,Han Z,Lin W,Lin X,Lu Q,Liu Y,Chang Q,Wu S

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND:Surgery is a potential trigger of Guillain-Barré syndrome (GBS), a disorder which leads to an autoimmune-mediated attack of peripheral nerves. The present study was designed to explore clinical features of post-surgical GBS compared with those of general GBS in order to provide better clinical advice to pati...

journal_title：BMC neurology

authors： Gong Q,Liu S,Liu Y,Yao J,Fu X,Xiao Z,Lu Z

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND:The insular cortex is not routinely removed in modified functional hemispherectomy due to the risk of injury to the main arteries and to deep structures. Our study evaluates the safety and usefulness of applying intraoperative electrocorticography (ECoG) on the insular during the hemispherectomy. METHODS:We...

journal_title：BMC neurology

authors： Kim GH,Seo JH,Baumgartner JE,Ajmal F,Lee KH

更新日期：2017-08-25 00:00:00

abstract：BACKGROUND:Multiple pathogenic factors may contribute to the pathophysiology of Alzheimer's disease (AD). Peripheral blood markers have been used to assess biochemical changes associated with AD and mild cognitive impairment (MCI) and involved in their pathophysiology. METHODS:Plasma samples and clinical data were obt...

journal_title：BMC neurology

authors： Kim SM,Song J,Kim S,Han C,Park MH,Koh Y,Jo SA,Kim YY

更新日期：2011-05-12 00:00:00

abstract：BACKGROUND:The autophagic vacuolar myopathies (AVM) are a group of inherited myopathies defined by the presence of autophagic vacuoles in pathological muscle specimens. AVM can be categorized into three groups: acid maltase deficiency, myopathies characterized by autophagic vacuoles with unique sarcolemmal features, an...

journal_title：BMC neurology

authors： Bokuda K,Sugaya K,Tamura S,Miyamoto K,Matsubara S,Komori T

更新日期：2012-11-21 00:00:00

abstract：BACKGROUND:Effective control of (upright) body posture requires a proper representation of body orientation. Stroke patients with pusher syndrome were shown to suffer from severely disturbed perception of own body orientation. They experience their body as oriented 'upright' when actually tilted by nearly 20 degrees to...

journal_title：BMC neurology

authors： Johannsen L,Broetz D,Karnath HO

更新日期：2006-08-23 00:00:00

abstract：BACKGROUND:Although free radicals have been reported to play a role in the expansion of ischemic brain lesions, the effect of free radical scavengers is still under debate. In this study, the temporal profile of ischemic stroke lesion sizes was assessed for more than one year to evaluate the effect of edaravone which m...

journal_title：BMC neurology

authors： Nakase T,Yoshioka S,Suzuki A

更新日期：2011-03-30 00:00:00

abstract：BACKGROUND:Intravenous thrombolysis has been recently introduced in Nepal for the management of acute ischemic stroke. Pre-hospital delay is one of the main reasons that hinder thrombolytic therapy. The objective of this study was to evaluate the status of prehospital delay and thrombolysis in Nepal. METHODS:Data were...

journal_title：BMC neurology

authors： Nepal G,Yadav JK,Basnet B,Shrestha TM,Kharel G,Ojha R

更新日期：2019-07-09 00:00:00

abstract：BACKGROUND:Sciatica is a condition that is characterised by radicular pain in the leg and primarily caused by a herniated lumbar intervertebral disk. In addition to leg pain, patients can experience back pain, leg numbness and leg weakness resulting in decreased productivity and social activity. The majority of sciatic...

journal_title：BMC neurology

authors： Verheijen E,Munts AG,van Haagen O,de Vries D,Dekkers O,van den Hout W,Vleggeert-Lankamp C

更新日期：2019-09-03 00:00:00

abstract：BACKGROUND:Anti-epileptic drugs (AEDs) are frequently prescribed to persons with HIV/AIDS receiving combination antiretroviral therapy (cART) although the extent of AED use and their interactions with cART are uncertain. Herein, AED usage, associated toxicities and immune consequences were investigated. METHODS:HIV re...

journal_title：BMC neurology

authors： Lee K,Vivithanaporn P,Siemieniuk RA,Krentz HB,Maingat F,Gill MJ,Power C

更新日期：2010-06-17 00:00:00

abstract：BACKGROUND:Infectious basilar artery (BA) aneurysm has been occasionally reported to be generated from meningitis following transcranial operation. However, infectious BA aneurysm formed by intracranial infection after endoscopic endonasal operation has never been reported. CASE PRESENTATION:A 53-year-old man who was ...

journal_title：BMC neurology

authors： Wang X,Chen G,Li M,Liang J,Guo H,Song G,Bao Y

更新日期：2020-03-14 00:00:00

abstract：BACKGROUND:A number of emerging studies have evaluated clot composition in acute ischemic stroke. Studies of clot composition of embolic strokes of undetermined strokes are lacking. OBJECTIVES:We sought to analyze the RBC to platelet ratios in clots and correlated our findings with stroke etiology. METHODS:This was a...

journal_title：BMC neurology

authors： Nouh A,Mehta T,Hussain M,Song X,Ollenschleger M

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:Internal jugular vein stenosis (IJVS), characterized by a series of clinical manifestations, such as head and neck symptoms, visual and ear symptoms, as well as sleep disorder, has been receiving attention in recent years. However, its' etiologies are not fully understood. CASE PRESENTATION:We report a case...

journal_title：BMC neurology

authors： Li M,Sun Y,Chan CC,Fan C,Ji X,Meng R

更新日期：2019-06-04 00:00:00

abstract：BACKGROUND:Spastic paraplegia, optic atrophy and neuropathy (Spoan syndrome) is an autosomal recessive disease with approximately 70 cases recorded in Brazil and Egypt. METHODS:This is a prospective longitudinal study performed with 47 patients affected with Spoan syndrome of seven communities of Rio Grande do Norte (...

journal_title：BMC neurology

authors： Galvão CRC,Cavalcante PMA,Olinda R,Graciani Z,Zatz M,Kok F,Santos S,Lancman S

更新日期：2019-10-27 00:00:00

abstract：BACKGROUND:Acute ischemic stroke attack with and without a recent TIA may differ in clinical risk factors, and this may affect treatment outcomes following thrombolytic therapy. We examined whether the odds of exclusion or inclusion for thrombolytic therapy are greater in ischemic stroke with TIA less than 24 h precedi...

journal_title：BMC neurology

authors： Poupore N,Strat D,Mackey T,Snell A,Nathaniel T

更新日期：2020-05-19 00:00:00