Delayed minocycline but not delayed mild hypothermia protects against embolic stroke.

abstract：BACKGROUND:Sarcoidosis is a multi-organ disease of unknown etiology characterised by the presence of epithelioid granulomas, without caseous necrosis. Systemic sarcoidosis is rare among children, while neurosarcoidosis in children is even rarer whether it is systemic or not. CASE PRESENTATION:We described the case of ...

journal_title：BMC neurology

authors： Shijo K,Moro N,Sasano M,Watanabe M,Yagasaki H,Takahashi S,Homma T,Yoshino A

更新日期：2018-05-29 00:00:00

abstract：BACKGROUND:Although free radicals have been reported to play a role in the expansion of ischemic brain lesions, the effect of free radical scavengers is still under debate. In this study, the temporal profile of ischemic stroke lesion sizes was assessed for more than one year to evaluate the effect of edaravone which m...

journal_title：BMC neurology

authors： Nakase T,Yoshioka S,Suzuki A

更新日期：2011-03-30 00:00:00

abstract：BACKGROUND:Intracranial hemorrhage in central nervous system lymphoma is extremely rare. T2*-weighted gradient-echo magnetic resonance imaging is of particularly use in detecting silent hemorrhage as hypointense signals due to the deposition of paramagnetic hemosiderin or mineralization. Multifocal hemosiderin depositi...

journal_title：BMC neurology

authors： Yang XZ,Ni J,Cui LY

更新日期：2014-09-25 00:00:00

abstract：BACKGROUND:Gall bladder cancer (GBC) is associated with abdominal pain, lump, nausea, vomiting, and jaundice due to either gall bladder mass or the involved adjacent peritoneal structures. Gall bladder cancer presenting as refractory epilepsy is rare. Here we report a young female GBC patient who presented with an atyp...

journal_title：BMC neurology

authors： Pandey S,Garg RK,Malhotra HS,Uniyal R,Kumar N

更新日期：2019-05-10 00:00:00

abstract：BACKGROUND:Facioscapulohumeral muscular dystrophy (FSHD) is a dominantly-inherited progressive muscular dystrophy caused by de-repression of the DUX4 gene, which causes disease by a toxic-gain-of-function. As molecularly targeted drugs move from preclinical testing into human trials, it is essential that we validate cl...

journal_title：BMC neurology

authors： LoRusso S,Johnson NE,McDermott MP,Eichinger K,Butterfield RJ,Carraro E,Higgs K,Lewis L,Mul K,Sacconi S,Sansone VA,Shieh P,van Engelen B,Wagner K,Wang L,Statland JM,Tawil R,ReSolve Investigators and the FSHD CTRN18.

更新日期：2019-09-10 00:00:00

abstract：BACKGROUND:The use of vestibular rehabilitation principles in the management of gaze and postural stability impairments in people with multiple sclerosis (PwMS) has shown promise in pilot work completed in our lab and in a recently published randomized clinical trial (RCT). However, further work is needed to fully quan...

journal_title：BMC neurology

authors： Loyd BJ,Fangman A,Peterson DS,Gappmaier E,Schubert MC,Thackery A,Dibble L

更新日期：2019-06-10 00:00:00

abstract：BACKGROUND:Prediction of clinical outcome in the acute stage of ischaemic stroke can be difficult when based on patient characteristics, clinical findings and on non-contrast CT. CT perfusion and CT angiography may provide additional prognostic information and guide treatment in the early stage. We present the study pr...

journal_title：BMC neurology

authors： van Seeters T,Biessels GJ,van der Schaaf IC,Dankbaar JW,Horsch AD,Luitse MJ,Niesten JM,Mali WP,Kappelle LJ,van der Graaf Y,Velthuis BK,DUST investigators.

更新日期：2014-02-25 00:00:00

abstract：BACKGROUND:The X-linked form of Charcot-Marie-Tooth disease type 1 (CMTX1) is an inherited peripheral neuropathy that arises in patients with mutations in the gap-junction beta-1 gene (GJB1). CASE PRESENTATION:Three young male patients from Southern China with pes cavus experienced multiple episodes of transient centr...

journal_title：BMC neurology

authors： Liang Y,Liu J,Cheng D,Wu Y,Mo L,Huang W

更新日期：2019-12-16 00:00:00

abstract：BACKGROUND:Chronic low back pain (CLBP) has been shown to be associated with various pathophysiological changes at several level of the sensorimotor system, pointing to a general hypersensitivity in CLBP patients. The aim of the present study was to investigate signs of generalized mechanical pain hypersensitivity in C...

journal_title：BMC neurology

authors： Puta C,Schulz B,Schoeler S,Magerl W,Gabriel B,Gabriel HH,Miltner WH,Weiss T

更新日期：2012-09-21 00:00:00

abstract：BACKGROUND:Patients with acute stroke are particularly vulnerable to delirium episodes. Although delirium detection is important, no evidence-based recommendations have been established to date on how these patients should be routinely screened for delirium or which tool should be used for this purpose in this populati...

journal_title：BMC neurology

authors： Mansutti I,Saiani L,Palese A

更新日期：2019-12-02 00:00:00

abstract：BACKGROUND:Robotic devices are expected to be widely used in various applications including support for the independent mobility of the elderly with muscle weakness and people with impaired motor function as well as support for nursing care that involves heavy laborious work. We evaluated the effects of a hybrid assist...

journal_title：BMC neurology

authors： Maeshima S,Osawa A,Nishio D,Hirano Y,Takeda K,Kigawa H,Sankai Y

更新日期：2011-09-27 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea is a common sleep disorder in stroke patients. Obstructive sleep apnea is associated with stroke severity and poor functional outcome. Continuous positive airway pressure seems to improve functional recovery in stroke rehabilitation. To date, the effect of continuous positive airway p...

journal_title：BMC neurology

authors： Aaronson JA,van Bennekom CA,Hofman WF,van Bezeij T,van den Aardweg JG,Groet E,Kylstra WA,Schmand BA

更新日期：2014-02-25 00:00:00

abstract：BACKGROUND:To evaluate the relationship between the flow signal intensity of branch arteries distal to the stenosis on 3-dimensional (3D) time-of-flight (TOF) magnetic resonance angiography (MRA) and the risk of stroke recurrence in patients with severe middle cerebral artery (MCA) trunk stenosis. METHODS:We prospecti...

journal_title：BMC neurology

authors： Chen H,Li Z,Hong H,Xing S,Liu G,Zhang A,Tan S,Zhang J,Zeng J

更新日期：2015-09-16 00:00:00

abstract：BACKGROUNDS:Glioma is the most fatal primary brain glioma in central nervous system mainly attributed to its high invasion. Prucalopride, a Serotonin-4 (5-HT4) receptor agonist, has been reported to regulate neurodevelopment. This study aimed to investigate the influence of the Prucalopride on glioma cells and unveil u...

journal_title：BMC neurology

authors： Qiao H,Wang YB,Gao YM,Bi LL

更新日期：2018-06-04 00:00:00

abstract：BACKGROUND:Spinal muscular atrophy (SMA) is an autosomal recessive disorder that affects the motoneurons of the spinal anterior horn, resulting in hypotonia and muscle weakness. The disease is caused by deletion or mutation in the telomeric copy of SMN gene (SMN1) and clinical severity is in part determined by the copy...

journal_title：BMC neurology

authors： Darbar IA,Plaggert PG,Resende MB,Zanoteli E,Reed UC

更新日期：2011-03-24 00:00:00

abstract：BACKGROUND:Room tilt illusion (RTI) is a rare symptom of higher vestibular dysfunction, consisting of a transient vertical rotation of the visual scene in the sagittal or coronal plane, most often 90o or 180o, without any alteration in shape, size and color of objects. CASE PRESENTATION:A 63-year-old woman with a hist...

journal_title：BMC neurology

authors： Arntzen K,Alstadhaug KB

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:Clinical trials are the hallmark of evidence-based medicine, but recruitment is often challenging, especially in stroke trials investigating patients not being able to give informed consent. In some nations, ethics committees will not approve of inclusion in a clinical study via consent of a legal representa...

journal_title：BMC neurology

authors： Hotter B,Ulm L,Hoffmann S,Katan M,Montaner J,Bustamante A,Meisel A

更新日期：2017-12-04 00:00:00

abstract：BACKGROUND:Evidence indicates that the continuation of therapy among community-dwelling stroke survivors improves physical function. Community rehabilitation programmes often face limitations in terms of resources. It is imperative to include new motivational interventions to encourage some level of non-clinician manag...

journal_title：BMC neurology

authors： Singh DK,Mohd Nordin NA,Abd Aziz NA,Lim BK,Soh LC

更新日期：2013-12-13 00:00:00

abstract：BACKGROUND:Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants for the treatment of depression in patients with Parkinson's Disease (PD) but data on their efficacy are controversial. METHODS:We conducted a systematic review and meta-analysis of randomized controlled trials ...

journal_title：BMC neurology

authors： Skapinakis P,Bakola E,Salanti G,Lewis G,Kyritsis AP,Mavreas V

更新日期：2010-06-21 00:00:00

abstract：BACKGROUND:Acceptance and Commitment Therapy (ACT), as a type of behavioral therapy, attempts to respond to changes in people's performance and their relationship to events. ACT can affect sleep quality by providing techniques to enhance the flexibility of patients' thoughts, yet maintaining mindfullness. Therefore, fo...

journal_title：BMC neurology

authors： Salari N,Khazaie H,Hosseinian-Far A,Khaledi-Paveh B,Ghasemi H,Mohammadi M,Shohaimi S

更新日期：2020-08-13 00:00:00

abstract：BACKGROUND:There is much discourse in healthcare about the importance of client-centred rehabilitation, however in the realm of community-based therapy post-stroke there has been little investigation into the efficacy of goal-directed practice that reflects patients' valued activities. In addition, the effect of active...

journal_title：BMC neurology

authors： Graven C,Brock K,Hill K,Ames D,Cotton S,Joubert L

更新日期：2011-06-18 00:00:00

abstract：BACKGROUND:Ventral intermediate thalamic nucleus (VIM) deep brain stimulation (DBS) is an effective treatment for tremor, but there is limited data on long-term efficacy and mortality after VIM-DBS. Here we report the analysis of patient satisfaction and mortality in all patients treated in our center 1996-2010 with VI...

journal_title：BMC neurology

authors： Børretzen MN,Bjerknes S,Sæhle T,Skjelland M,Skogseid IM,Toft M,Dietrichs E

更新日期：2014-06-05 00:00:00

abstract：BACKGROUND:The time from injury to surgery (TIS) is critical in the functional recovery of individuals with traumatic acute subdural hematoma (TASDH). However, only few studies have confirmed such notion. METHODS:The data of TASDH patients who were surgically treated in Chia-Yi Christian Hospital between January 2008 ...

journal_title：BMC neurology

authors： Chen SH,Sun JM,Fang WK

更新日期：2020-06-04 00:00:00

abstract：BACKGROUND:Data from different studies suggest a favourable association between pretreatment with statins or hypercholesterolemia and outcome after ischaemic stroke. We examined whether there were differences in in-hospital mortality according to the presence or absence of statin therapy in a large population of first-...

journal_title：BMC neurology

authors： Arboix A,García-Eroles L,Oliveres M,Targa C,Balcells M,Massons J

更新日期：2010-06-18 00:00:00

abstract：BACKGROUND:The WHOQOL-BREF is a frequently used instrument for the assessment of health-related quality of life. Unlike other generic instruments used for the assessment of this construct, little is known about its properties in individuals with headache disorders. The present study examines the reliability and factori...

journal_title：BMC neurology

authors： Brzoska P

更新日期：2020-07-03 00:00:00

abstract：BACKGROUND:Effective control of (upright) body posture requires a proper representation of body orientation. Stroke patients with pusher syndrome were shown to suffer from severely disturbed perception of own body orientation. They experience their body as oriented 'upright' when actually tilted by nearly 20 degrees to...

journal_title：BMC neurology

authors： Johannsen L,Broetz D,Karnath HO

更新日期：2006-08-23 00:00:00

abstract：BACKGROUND:This study aims to investigate the clinical value of two kinds of vestibular-evoked myogenic potentials in patients with sudden sensorineural hearing loss (SSNHL). METHODS:A total of 82 patients were divided into two groups: vertigo group and non-vertigo group. All patients underwent examinations for pure t...

journal_title：BMC neurology

authors： Wang Y,Gu ST,Bao XL,Guo JL

更新日期：2019-12-21 00:00:00

abstract：BACKGROUND:Amongst Sardinians the human leukocyte antigen (HLA) DRB1-DQB1 haplotypes *15:02-*06:01, *16:01-*05:02, *14:01-4-*05:03 are protective for multiple sclerosis (MS), while *13:03-*03:01, *04:05-*03:01, *03:01-*02:01, *15:01-*06:02 and Mycobacterium avium subspecies paratubercolosis (MAP) are predisposing facto...

journal_title：BMC neurology

authors： Frau J,Cossu D,Sardu C,Mameli G,Coghe G,Lorefice L,Fenu G,Tranquilli S,Sechi LA,Marrosu MG,Cocco E

更新日期：2016-08-23 00:00:00

abstract：BACKGROUND:Overweight is reported as a side effect of SDR. The aims were to study the development of weight, height and body mass index (BMI) during five years after SDR. METHODS:This prospective, longitudinal and practice-based study included all 56 children with CP spastic diplegia undergoing SDR from the start in M...

journal_title：BMC neurology

authors： Westbom L,Lundkvist Josenby A,Wagner P,Nordmark E

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Adrenomyeloneuropathy (AMN) is one of several phenotypes of the adrenoleukodystrophy spectrum caused by mutations in the ABCD1 gene on the X chromosome. An inflammatory component is part of the disease complex ranging from severe childhood CNS demyelination to spinal cord and peripheral nerve degeneration. ...

journal_title：BMC neurology

authors： Jønch AE,Danielsen ER,Thomsen C,Meden P,Svenstrup K,Nielsen JE

更新日期：2012-09-26 00:00:00