Abstract:
BACKGROUND:Patients with ischemic cerebrovascular diseases are more likely to suffer from intracranial aneurysms, and their surgical treatment has a growing controversy in this condition. The current case series was aimed at exploring surgical treatment and perioperative management of intracranial aneurysms in Chinese patients with ischemic cerebrovascular diseases. METHODS:Minimally invasive surgical approach through small pterion or inferolateral forehead was applied in 31 patients. Anti-platelet drugs were withdrawn 1 week before surgical operation. Systolic blood pressure was controlled to be more than 110 mmHg and increased by 20% after the clipping of intracranial aneurysms. Branches of external carotid artery were spared to ensure collateral circulation. Temporary blocking was minimized and ischemic time was shortened during surgical operation. RESULTS:Patients had an average age of 66 (46-78) years, and proportion of males was 39% (12 males). There were 35 unruptured intracranial aneurysms with a diameter more than 5 mm. There were 20 posterior communicating and anterior choroidal aneurysms (57%), seveb middle cerebral aneurysms (20%), and eight anterior communicating aneurysms (23%), with 21 lobular aneurysms (60%). Twenty-nine patients had normal neurological function (Glasgow Outcome Scale [GOS] 5), one patient with mild neurological defect (GOS 4), and one patient with severe neurological defect (GOS 3) at discharge. Meanwhile, there were 26 patients with modified Rankin Scale (MRS) 0-1, 4 patient with MRS 2, and one patient with MRS 3 at discharge. There were four patients lost during the follow-up. During the follow-up, 26 patients had normal neurological function (GOS 5), and one patient with severe neurological defect (GOS 3). Meanwhile, there were 25 patients with MRS 0-1, one patient with MRS 2, and one patient with MRS 3. All patients had no recurrence of intracranial aneurysms after operation. CONCLUSIONS:The current case series found that minimally invasive surgical approach and intraoperative monitoring, supplemented by effective management of cerebrovascular perfusion, circulation and coagulation, can promote the treatment of intracranial aneurysms and prevent the development of cerebral ischemia and aneurysm rupture in Chinese patients with ischemic cerebrovascular diseases. Future studies with large sample size will be needed to confirm the results from the current case series.
journal_name
BMC Neuroljournal_title
BMC neurologyauthors
Zheng Y,Wu Cdoi
10.1186/s12883-018-1147-8subject
Has Abstractpub_date
2018-09-14 00:00:00pages
142issue
1issn
1471-2377pii
10.1186/s12883-018-1147-8journal_volume
18pub_type
杂志文章相关文献
BMC Neurology文献大全abstract:BACKGROUND:Chronic fatigue syndrome (CFS) is a disabling condition that affects approximately 800,000 adult Americans. The pathophysiology remains unknown and there are no diagnostic markers or characteristic physical signs or laboratory abnormalities. Most CFS patients complain of unrefreshing sleep and many of the po...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-4-6
更新日期:2004-04-19 00:00:00
abstract:BACKGROUND:The clinical impact of neutralizing antibodies against interferon-beta (NAb) is controversial. Their presence can lead to a decrease in interferon-beta (IFNβ) efficacy. Fatigue reported in patients with multiple sclerosis (MS) may be associated with an unfavorable clinical course. We conducted a prospective ...
journal_title:BMC neurology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12883-014-0215-y
更新日期:2014-11-30 00:00:00
abstract:BACKGROUND:This study aimed to determine the risk of thromboembolic events in patients with junctional bradycardia(JB). METHODS:We retrospectively reviewed electrocardiograms(ECGs) for 380,682 patients. Those with JB on an ECG at least twice over a ≥3-month interval were included for analysis. We additionally included...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0645-9
更新日期:2016-07-25 00:00:00
abstract:BACKGROUND:The WHOQOL-BREF is a frequently used instrument for the assessment of health-related quality of life. Unlike other generic instruments used for the assessment of this construct, little is known about its properties in individuals with headache disorders. The present study examines the reliability and factori...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-01845-7
更新日期:2020-07-03 00:00:00
abstract:BACKGROUND:Autosomal recessive cerebellar ataxias (ARCA) are a group of neurodegenerative disorders characterized by early onset of gait impairment, disturbed limb coordination, dysarthria, and eye movement abnormalities, most likely due to the degeneration of cerebellum, brainstem, and spinal cord. Despite of the rari...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0696-y
更新日期:2016-09-20 00:00:00
abstract:BACKGROUND:Complications after stroke have been associated with poor outcome. Modern stroke treatment might reduce the occurrence of complications. The aim of this study was to investigate whether the frequency and type of complications during the first week after stroke has changed in patients treated in a stroke unit...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0654-8
更新日期:2016-08-11 00:00:00
abstract:BACKGROUND:Complaints of unrefreshing sleep are a prominent component of chronic fatigue syndrome (CFS); yet, polysomnographic studies have not consistently documented sleep abnormalities in CFS patients. We conducted this study to determine whether alterations in objective sleep characteristics are associated with sub...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-7-40
更新日期:2007-12-05 00:00:00
abstract:BACKGROUND:The production of inflammatory cytokines resulting from amyloid β (Aβ) is associated with the initiation of Alzheimer's disease (AD). Atorvastatin (ATV) has been reported to improve AD, however, it is unclear how the anti-inflammatory mechanism is linked with its protection against the impairment of spatial ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0533-3
更新日期:2016-02-04 00:00:00
abstract:BACKGROUND:Migraine is a highly prevalent disorder. The disability provoked by its attacks results in suffering as well as considerable economic and social losses. The objective of migraine acute treatment is to restore the patient to normal function as quickly and consistently as possible. There are numerous drugs ava...
journal_title:BMC neurology
pub_type: 杂志文章,评审
doi:10.1186/1471-2377-4-4
更新日期:2004-01-28 00:00:00
abstract:BACKGROUND:The mechanisms underlying the interictal habituation deficit of cortical visual evoked potentials (VEP) in migraine are not well understood. Abnormal long-term functional plasticity of the visual cortex may play a role and it can be assessed experimentally by light deprivation (LD). METHODS:We have compared...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-11-91
更新日期:2011-07-27 00:00:00
abstract:BACKGROUND:Dorsolateral medullary infarction is a typical cerebral infarction which is characterized by Wallenberg's syndrome. Neurotrophic keratopathy is an uncommon consequence of dorsolateral medullary infarction. At present, the protocol is aimed to study the dynamic changes in corneal innervation and the ocular su...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-02030-6
更新日期:2021-01-12 00:00:00
abstract:BACKGROUND:The COVID-19 pandemic, which broke out in Wuhan in 2019, has become the global health crisis of our time. Elderly patients with certain fundamental diseases are more likely to develop severe cases. The secondary lesion following viral infection have only rarely been reported. CASE PRESENTATION:We here repor...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-02033-3
更新日期:2021-01-05 00:00:00
abstract:BACKGROUND:Epigenetics underlying refractory epilepsy is poorly understood. DNA methylation may affect gene expression in epilepsy patients without affecting DNA sequences. Herein, we investigated the association between Carbamazepine-resistant (CBZ-resistant) epilepsy and EPHX1 methylation in a northern Han Chinese po...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-019-1308-4
更新日期:2019-06-04 00:00:00
abstract:BACKGROUND:Taste disorder is a common symptom in the general population. Several studies have shown that patients with neurological disorders, such as amyotrophic lateral sclerosis and Parkinson's disease, develop taste disturbance. Facial onset sensory and motor neuronopathy (FOSMN) is a rare disease characterized by ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-020-01639-x
更新日期:2020-02-29 00:00:00
abstract:BACKGROUND:There is conflicting information as to whether antiretroviral drugs with better central nervous system (CNS) penetration (neuroHAART) assist in improving neurocognitive function and suppressing cerebrospinal fluid (CSF) HIV RNA. The current review aims to better synthesise existing literature by using an inn...
journal_title:BMC neurology
pub_type: 杂志文章,评审
doi:10.1186/1471-2377-11-148
更新日期:2011-11-22 00:00:00
abstract:BACKGROUND:The cognitive consequences of carbon monoxide (CO) poisoning are well described. However, most studies have been carried out without an ad-hoc group of control subjects. The main aim of this study was to evaluate cognitive and psychiatric outcome after CO exposure during the storm Klaus in the South West of ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-14-153
更新日期:2014-07-21 00:00:00
abstract:BACKGROUND:Almost 40% of stroke patients have a poor outcome at 3 months after the index event. Predictors for stroke outcome in the early acute phase may help to tailor stroke treatment. Infection and inflammation are considered to influence stroke outcome. METHODS:In a prospective multicenter study in Germany and Sp...
journal_title:BMC neurology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12883-019-1375-6
更新日期:2019-07-03 00:00:00
abstract:BACKGROUND:Volume isotropic turbo spin-echo acquisition (VISTA) is a new method similar to the 3D black-blood imaging method that enables visualization of a intramural hematoma. T1-VISTA has recently been applied in the diagnosis of intracranial arterial dissection. However, the identification of an intramural hematoma...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0637-9
更新日期:2016-07-29 00:00:00
abstract:BACKGROUND:Patients with acute stroke are particularly vulnerable to delirium episodes. Although delirium detection is important, no evidence-based recommendations have been established to date on how these patients should be routinely screened for delirium or which tool should be used for this purpose in this populati...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-019-1547-4
更新日期:2019-12-02 00:00:00
abstract:BACKGROUND:Recent exercise guidelines for people with multiple sclerosis (MS) recommend a minimum of 30 min moderate intensity aerobic exercise and resistance exercise twice per week. This trial compared the secondary outcomes of a combined 10-week guideline based intervention and a Social Cognitive Theory (SCT) educat...
journal_title:BMC neurology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12883-017-0898-y
更新日期:2017-06-24 00:00:00
abstract:BACKGROUND:Overweight is reported as a side effect of SDR. The aims were to study the development of weight, height and body mass index (BMI) during five years after SDR. METHODS:This prospective, longitudinal and practice-based study included all 56 children with CP spastic diplegia undergoing SDR from the start in M...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-10-57
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Cerebral amyloid angiopathy (CAA) refers to the deposition of β-amyloid (Aβ) peptides in the wall of brain vasculature, commonly involving capillaries and arterioles. Also being considered a part of CAA is the Aβ deposition in leptomeninge. The cellular origin of angiopathic Aβ and the pathogenic course of C...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0327-z
更新日期:2015-05-02 00:00:00
abstract:BACKGROUND:Previous epidemiologic studies have examined the association of smoking with amyotrophic lateral sclerosis (ALS) incidence, but their results have been inconsistent. Moreover, limited information exists on the association between smoking and survival in ALS patients. We evaluated the association of smoking w...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-10-6
更新日期:2010-01-14 00:00:00
abstract:BACKGROUND:Anti-Myelin oligodendrocyte glycoprotein (MOG) antibodies are detected in various demyelinating diseases, such as pediatric acute disseminated encephalomyelitis (ADEM), recurrent optic neuritis, and aquaporin-4 antibody-seronegative neuromyelitis optica spectrum disorder. We present a patient who developed a...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-017-0858-6
更新日期:2017-04-19 00:00:00
abstract:BACKGROUND:Clinical reasoning in Neurology is based on general associations which help to deduce the site of the lesion. However, even "golden principles" may occasionally be deceptive. Here, we describe the case of subacute flaccid tetraparesis due to motor cortical lesions. To our knowledge, this is the first report ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-017-0814-5
更新日期:2017-02-10 00:00:00
abstract::Following publication of the original article [1], the authors reported an error in Table 2 wherein the item numbering in the first column is wrong. ...
journal_title:BMC neurology
pub_type: 已发布勘误
doi:10.1186/s12883-019-1454-8
更新日期:2019-09-13 00:00:00
abstract::In clinical neurology, a comprehensive understanding of consciousness has been regarded as an abstract concept--best left to philosophers. However, times are changing and the need to clinically assess consciousness is increasingly becoming a real-world, practical challenge. Current methods for evaluating altered level...
journal_title:BMC neurology
pub_type: 杂志文章,评审
doi:10.1186/1471-2377-10-11
更新日期:2010-01-29 00:00:00
abstract:BACKGROUND:Many migraineurs who seek care in headache clinics are refractory to treatment, despite advances in headache therapies. Epidemiology is poorly characterized, because diagnostic criteria for refractory migraine were not available until recently. We aimed to determine the frequency of refractory migraine in pa...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-11-94
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:The study of muscle metabolism by near-infrared spectroscopy (NIRS) has been poorly implemented in multiple sclerosis (MS). Aims of the study were to compare resting muscle oxygen consumption (rmVO2) at gastrocnemius in MS patients and in age-matched healthy controls (HC) measured using NIRS, and to evaluate...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/1471-2377-13-52
更新日期:2013-05-29 00:00:00
abstract:BACKGROUND:Rett syndrome (RTT) is a severe neurodevelopmental disorder mainly affecting females. One of the main clinical manifestations is hand stereotypies, which is presumed to based on dysfunction rather than on structural impairment. Reflex interictal discharge precipitated by tapping-lips in electroencephalogram ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-019-1296-4
更新日期:2019-05-01 00:00:00