Influenza D Virus: Serological Evidence in the Italian Population from 2005 to 2017.

abstract：:We mapped the hemagglutinin-esterase (HE) antigenic epitopes of the influenza C virus on the three-dimensional (3D) structure of the HE glycoprotein using 246 escape mutants that were selected by a panel of nine anti-HE monoclonal antibodies (MAbs), including seven of the C/Ann Arbor/1/50 virus and two of the C/Yamaga...

journal_title：Viruses

authors： Matsuzaki Y,Sugawara K,Furuse Y,Shimotai Y,Hongo S,Mizuta K,Nishimura H

更新日期：2018-08-09 00:00:00

abstract：:African swine fever (ASF) has become the major threat for the global swine industry. Furthermore, the epidemiological situation of African swine fever virus (ASFV) in some endemic regions of Sub-Saharan Africa is worse than ever, with multiple virus strains and genotypes currently circulating in a given area. Despite ...

journal_title：Viruses

authors： Lopez E,van Heerden J,Bosch-Camós L,Accensi F,Navas MJ,López-Monteagudo P,Argilaguet J,Gallardo C,Pina-Pedrero S,Salas ML,Salt J,Rodriguez F

更新日期：2020-12-21 00:00:00

abstract：:The chikungunya virus (CHIKV) is an emerging pathogen with widespread distribution in regions of Africa, India, and Asia that threatens to spread into temperate climates with the introduction of its major vector, Aedes albopictus. CHIKV causes a disease frequently misdiagnosed as dengue fever, with potentially life-th...

journal_title：Viruses

authors： Mishra P,Furey C,Balaraman V,Fraser MJ

更新日期：2016-06-10 00:00:00

abstract：:Live attenuated influenza vaccines (LAIV) have prevented morbidity and mortality associated with influenza viral infections for many years and represent the best therapeutic option to protect against influenza viral infections in humans. However, the development of LAIV has traditionally relied on empirical methods, s...

journal_title：Viruses

authors： Martínez-Sobrido L,Peersen O,Nogales A

更新日期：2018-10-15 00:00:00

abstract：:During the past ten years, several new hepatitis E viruses (HEVs) have been identified in various animal species. In parallel, the number of reports of autochthonous hepatitis E in Western countries has increased as well, raising the question of what role these possible animal reservoirs play in human infections. The a...

journal_title：Viruses

authors： Doceul V,Bagdassarian E,Demange A,Pavio N

更新日期：2016-10-03 00:00:00

abstract：:There is an ongoing global pandemic of human respiratory syncytial virus (RSV) infection that results in substantial annual morbidity and mortality. In Australia, RSV is a major cause of acute lower respiratory tract infections (ALRI). Nevertheless, little is known about the extent and origins of the genetic diversity...

journal_title：Viruses

authors： Di Giallonardo F,Kok J,Fernandez M,Carter I,Geoghegan JL,Dwyer DE,Holmes EC,Eden JS

更新日期：2018-09-06 00:00:00

abstract：:Human influenza A(H2N2) viruses emerged in 1957 and were replaced by A(H3N2) viruses in 1968. The antigenicity of human H2N2 viruses has been tested by using ferret antisera or mouse and human monoclonal antibodies. Here, we examined the antigenicity of human H2N2 viruses by using human plasma samples obtained from 50...

journal_title：Viruses

authors： Matsuzawa Y,Iwatsuki-Horimoto K,Nishimoto Y,Abe Y,Fukuyama S,Hamabata T,Okuda M,Go Y,Watanabe T,Imai M,Arai Y,Fouchier RAM,Yamayoshi S,Kawaoka Y

更新日期：2019-10-23 00:00:00

abstract：:Hematopoietic stem cell transplantation from anti-cytomegalovirus immunoglobulin G (anti-CMV-IgG) positive donors facilitated immunological recovery post-transplant, which may indicate that chronic CMV infection has an effect on the immune system. This can be seen in the recipients after reconstitution with donor lymp...

journal_title：Viruses

authors： Jaskula E,Dlubek D,Tarnowska A,Lange J,Mordak-Domagala M,Suchnicki K,Sedzimirska M,Borowik A,Mizia S,Lange A

更新日期：2015-03-23 00:00:00

abstract：:Viral outbreaks of varying frequencies and severities have caused panic and havoc across the globe throughout history. Influenza, small pox, measles, and yellow fever reverberated for centuries, causing huge burden for economies. The twenty-first century witnessed the most pathogenic and contagious virus outbreaks of ...

journal_title：Viruses

authors： Soman Pillai V,Krishna G,Valiya Veettil M

更新日期：2020-04-20 00:00:00

abstract：:Despite tremendous efforts over the course of many years, the quest for an effective HIV vaccine by the classical method of active immunization remains largely elusive. However, two recent studies in mice and macaques have now demonstrated a new strategy designated as Vectored ImmunoProphylaxis (VIP), which involves p...

journal_title：Viruses

authors： Yang L,Wang P

更新日期：2014-01-27 00:00:00

abstract：:The APOBEC3 family of proteins in mammals consists of cellular cytosine deaminases and well-known restriction factors against retroviruses, including lentiviruses. APOBEC3 genes are highly amplified and diversified in mammals, suggesting that their evolution and diversification have been driven by conflicts with ancie...

journal_title：Viruses

authors： Uriu K,Kosugi Y,Ito J,Sato K

更新日期：2021-01-17 00:00:00

abstract：:Avian influenza virus (AIV) is a highly diverse and widespread poultry pathogen. Itsevolution and adaptation may be affected by multiple host and ecological factors, which are stillpoorly understood. In the present study, a turkey-origin H9N2 AIV was used as a model toinvestigate the within-host diversity of the virus...

journal_title：Viruses

authors： Świętoń E,Tarasiuk K,Olszewska-Tomczyk M,Iwan E,Śmietanka K

更新日期：2020-03-16 00:00:00

abstract：:The begomoviruses (BGVs) are plant pathogens that evolved in the Old World during the Cretaceous and arrived to the New World (NW) in the Cenozoic era. A subgroup of NW BGVs, the "Squash leaf curl virus (SLCV) lineage" (S-Lin), includes viruses with unique characteristics. To get clues on the evolutionary origin of th...

journal_title：Viruses

authors： Torres-Herrera SI,Romero-Osorio A,Moreno-Valenzuela O,Pastor-Palacios G,Cardenas-Conejo Y,Ramírez-Prado JH,Riego-Ruiz L,Minero-García Y,Ambriz-Granados S,Argüello-Astorga GR

更新日期：2019-07-13 00:00:00

abstract：:One of the major obstacles that must be overcome in the design of effective lentiviral vaccines is the ability of lentiviruses to evolve in order to escape from neutralizing antibodies. The primary target for neutralizing antibodies is the highly variable viral envelope glycoprotein (Env), a glycoprotein that is essen...

journal_title：Viruses

authors： Hosie MJ,Pajek D,Samman A,Willett BJ

更新日期：2011-10-01 00:00:00

abstract：:While 25 compounds have been formally licensed for the treatment of HIV infection (AIDS), only seven licensed products are currently available for the treatment of chronic hepatitis B virus (HBV) infection: interferon-α, pegylated interferon-α, lamivudine, adefovir (dipivoxil), entecavir, telbivudine and tenofovir (di...

journal_title：Viruses

authors： De Clercq E,Férir G,Kaptein S,Neyts J

更新日期：2010-06-01 00:00:00

abstract：:Temperate bacteriophages possess a molecular switch, which regulates the lytic and lysogenic growth. The genomes of the temperate telomere phages N15, PY54 and ɸKO2 harbor a primary immunity region (immB) comprising genes for the prophage repressor, the lytic repressor and a putative antiterminator. The roles of these...

journal_title：Viruses

authors： Hammerl JA,Roschanski N,Lurz R,Johne R,Lanka E,Hertwig S

更新日期：2015-06-02 00:00:00

abstract：:Lassa virus (LASV) and Mopeia virus (MOPV) are two closely related Old-World mammarenaviruses. LASV causes severe hemorrhagic fever with high mortality in humans, whereas no case of MOPV infection has been reported. Comparing MOPV and LASV is a powerful strategy to unravel pathogenic mechanisms that occur during the c...

journal_title：Viruses

authors： Baillet N,Krieger S,Journeaux A,Caro V,Tangy F,Vidalain PO,Baize S

更新日期：2019-03-23 00:00:00

abstract：:Preclinical infection model systems are extremely valuable tools to aid in our understanding of Human Papillomavirus (HPV) biology, disease progression, prevention, and treatments. In this context, rodent papillomaviruses and their respective infection models are useful tools but remain underutilized resources in the ...

journal_title：Viruses

authors： Uberoi A,Lambert PF

更新日期：2017-11-27 00:00:00

abstract：:Nipah virus (NiV) is an emerging zoonotic virus that is transmitted by bats to humans and to pigs, causing severe respiratory disease and often fatal encephalitis. Antibodies directed against the NiV-glycoprotein (G) protein are known to play a major role in clearing NiV infection and in providing vaccine-induced prot...

journal_title：Viruses

authors： Kalodimou G,Veit S,Jany S,Kalinke U,Broder CC,Sutter G,Volz A

更新日期：2019-12-24 00:00:00

abstract：:Kobuviruses comprise three species, the Aichivirus A, Aichivirus B, and Aichivirus C (porcine kobuvirus). Porcine kobuvirus is endemic to pig farms and is not restricted geographically but, rather, is distributed worldwide. The complete genomic sequences of four porcine kobuvirus strains isolated during a diarrhea out...

journal_title：Viruses

authors： Fan S,Sun H,Ying Y,Gao X,Wang Z,Yu Y,Li Y,Wang T,Yu Z,Yang S,Zhao Y,Qin C,Gao Y,Xia X

更新日期：2013-10-18 00:00:00

abstract：:Bombyx mori bidensovirus (BmBDV) is a single-stranded DNA (ssDNA) virus from the genus Bidensovirus of the Bidnaviridae family, which, thus far, solely infects insects. It has a unique genome that contains bipartite DNA molecules (VD1 and VD2). In this study, we explored the detailed transcription mapping of the compl...

journal_title：Viruses

authors： Li R,Chang P,Lü P,Hu Z,Chen K,Yao Q,Yu Q

更新日期：2019-04-03 00:00:00

abstract：:The bacteriophage lambda replication initiation protein P exhibits a toxic effect on its Escherichia coli (E. coli) host, likely due to the formation of a dead-end P-DnaB complex, sequestering the replicative DnaB helicase from further activity. Intracellular expression of P triggers SOS-independent cellular filamenta...

journal_title：Viruses

authors： Hayes S,Wang W,Rajamanickam K,Chu A,Banerjee A,Hayes C

更新日期：2016-06-22 00:00:00

abstract：:Gammaherpesviruses like Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) subvert the ubiquitin proteasome system for their own benefit in order to facilitate viral gene expression and replication. In particular, viral tegument proteins that share sequence homology to the formylglycineamide r...

journal_title：Viruses

authors： Full F,Hahn AS,Großkopf AK,Ensser A

更新日期：2017-10-21 00:00:00

abstract：:For the past two decades, norovirus pandemic variants have emerged every 3⁻5 years, and dominate until they are replaced by alternate strains. However, this scenario changed in 2016 with the co-circulation of six prevalent viruses, three of which possessed the pandemic GII.4 Sydney 2012 capsid. An increased number of ...

journal_title：Viruses

authors： Lun JH,Hewitt J,Yan GJH,Enosi Tuipulotu D,Rawlinson WD,White PA

更新日期：2018-10-09 00:00:00

abstract：:The human cytomegalovirus (HCMV)-encoded protein kinase, pUL97, is considered a cyclin-dependent kinase (CDK) ortholog, due to shared structural and functional characteristics. The primary mechanism of CDK activation is binding to corresponding cyclins, including cyclin T1, which is the usual regulatory cofactor of CD...

journal_title：Viruses

authors： Graf L,Webel R,Wagner S,Hamilton ST,Rawlinson WD,Sticht H,Marschall M

更新日期：2013-12-18 00:00:00

abstract：:Bovine viral diarrhea virus (BVDV) is an important pathogen belonging to the Pestivirus genus, Flaviviridae family, which comprises viral species that causes an economic impact in animal production. Cattle are the natural host of BVDV and the main source of infection for pigs and other animal species. Due to its antig...

journal_title：Viruses

authors： de Oliveira LG,Mechler-Dreibi ML,Almeida HMS,Gatto IRH

更新日期：2020-05-31 00:00:00

abstract：:In this review, we describe the distribution and genetic diversity of sapoviruses detected among humans, animals and the environment in African countries. Databases were searched for studies conducted in African countries and published between Jan 2005 and Mar 2019. Only studies where RT- PCR was used for initial dete...

journal_title：Viruses

authors： Makhaola K,Moyo S,Kebaabetswe LP

更新日期：2020-04-27 00:00:00

abstract：:The morbillivirus genus comprises major human and animal pathogens, including the highly contagious measles virus. Morbilliviruses feature single stranded negative sense RNA genomes that are wrapped by a plasma membrane-derived lipid envelope. Genomes are encapsidated by the viral nucleocapsid protein forming ribonucl...

journal_title：Viruses

authors： Sourimant J,Plemper RK

更新日期：2016-09-10 00:00:00

abstract：:Food security is currently a global socio-political pressure point that is exacerbated by the everincreasing world population[...]. ...

journal_title：Viruses

authors： Mahony J,Casey E,van Sinderen D

更新日期：2020-02-13 00:00:00

abstract：BACKGROUND:Zika virus is a mosquito-borne flavivirus responsible for recent outbreaks of epidemic proportions in Latin America. Sexual transmission of the virus has been reported in 13 countries and may be an important route of infection. Sexual transmission of ZIKV has mostly been male-to-female, and persistence of vi...

journal_title：Viruses

authors： Mlera L,Bloom ME

更新日期：2019-01-09 00:00:00