Effect of Germinated Pigmented Rice "Superjami" on the Glucose Level, Antioxidant Defense System, and Bone Metabolism in Menopausal Rat Model.

Abstract:

:Women experience physical, mental, and social changes during menopause. It is important to maintain a healthy diet for effective menopause management. The effect of germinated Superjami, a deep violet colored rice cultivar, on the body weight, glucose level, antioxidant defense system, and bone metabolism in a menopausal rat model was investigated. The animals were randomly divided into three groups and fed with a normal diet (ND), a control diet supplemented with 20% (w/w) non-germinated Superjami flour (NGSF), or germinated Superjami flour (GSF) for eight weeks. The NGSF and GSF groups exhibited significantly lower body weight and fat, glucose and insulin contents, adipokine concentrations, and bone resorption biomarker levels, and higher antioxidant enzyme activities and 17-β-estradiol content than the ND group (p < 0.05). The GSF group showed greater glucose homeostasis, antioxidative, and bone metabolism-improving effects compared with the NGSF group. These findings demonstrate that germination could further improve the health-promoting properties of Superjami and that this germinated pigmented rice cultivar could be useful in the treatment and management of menopause-induced hyperglycemia, oxidative stress, and bone turnover imbalance.

journal_name

Nutrients

journal_title

Nutrients

authors

Chung SI,Ham TH,Kang MY

doi

10.3390/nu11092184

subject

Has Abstract

pub_date

2019-09-11 00:00:00

issue

9

issn

2072-6643

pii

nu11092184

journal_volume

11

pub_type

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