Kidney Disease in HIV Infection.

Abstract:

:Antiretroviral therapy (ART) has significantly improved life expectancy of infected subjects, generating a new epidemiological setting of people aging withHuman Immunodeficiency Virus (HIV). People living with HIV (PLWH), having longer life expectancy, now face several age-related conditions as well as side effects of long-term exposure of ART. Chronic kidney disease (CKD) is a common comorbidity in this population. CKD is a relentlessly progressive disease that may evolve toward end-stage renal disease (ESRD) and significantly affect quality of life and risk of death. Herein, we review current understanding of renal involvement in PLWH, mechanisms and risk factors for CKD as well as strategies for early recognition of renal dysfunction and best care of CKD.

journal_name

J Clin Med

authors

Alfano G,Cappelli G,Fontana F,Di Lullo L,Di Iorio B,Bellasi A,Guaraldi G

doi

10.3390/jcm8081254

subject

Has Abstract

pub_date

2019-08-19 00:00:00

issue

8

issn

2077-0383

pii

jcm8081254

journal_volume

8

pub_type

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